Sat.Jun 10, 2023 - Fri.Jun 16, 2023

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340B program reaches $100 billion in sales, while patients are left behind

PhRMA

The 340B Drug Pricing Program has grown yet again , exceeding $100 billion in sales in 2022 when 340B-priced medicines are measured at wholesale acquisition cost. Recent data from IQVIA shows 340B grew 12.2% year-over-year in 2022, continuing a trend in which 340B sales have almost doubled since 2018, outpacing growth of the total U.S. drug market.

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How Has Independent Pharmacy Evolved, and Where is it Heading Next?

Drug Topics

Drug Topics spoke to father and son pharmacist duo Grant and Austin Brown for a conversation about the evolution of the practice, the importance of holding elected officials accountable, and more.

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‘The drug bust paradox’: Study shows opioid deaths double after police action

STAT

Police drug busts are strongly associated with a large and sudden spike in overdose deaths, according to a new study. In the week following a major opioid bust, fatal overdoses in the same neighborhood in Indianapolis doubled, the analysis showed. Calls to 911 and the use of naloxone , the overdose-reversal medication, also spiked.

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BioNTech to defend itself against COVID-19 vaccine injury claim in Germany

Fierce Pharma

Two years after the initial COVID-19 vaccine push swept across the globe, Pfizer’s COVID-19 vaccine partner BioNTech is heading to court in its home country of Germany to defend itself against alle | The drugmaker will defend itself against claims from a German healthcare worker who sued the company for at least 150,000 euros ($161,500). The plaintiff alleges she suffered bodily harm resulting from Pfizer and BioNTech's Comirnaty vaccine.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Biopharmaceutical science powered by PRIDE

PhRMA

This June marks Lesbian, Gay, Bisexual, Transgender and Queer (LGBTQ+) Pride Month. At PhRMA, we’re proud to celebrate the diversity and inclusion of our LGBTQ+ colleagues and the patients our companies aim to help. As an industry driven by science, we believe diversity in the lab drives greater collaboration, scientific advancement and groundbreaking medicines impacting the lives of patients.

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Generative AI Framework Could Help Create Better Medicine Faster

Drug Topics

G2Retro, developed by investigators from Ohio State University, can produce hundreds of new reaction predictions in just a few minutes.

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More Trending

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Bayer needs 'midsize acquisition' to reach $10B oncology sales goal, exec says

Fierce Pharma

Bayer recently laid out its ambition | Bayer recently laid out its ambition to achieve $10 billion in sales from its oncology business by 2030 and become a top 10 cancer drug player. To get there, the company is looking outside for a “midsize acquisition,” Bayer’s oncology chief Christine Roth said.

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AMA asks doctors to de-emphasize use of BMI in gauging health and obesity

STAT

CHICAGO — The American Medical Association on Tuesday strongly criticized the body mass index , urging doctors to de-emphasize its use in assessing health and obesity and acknowledging that the measurement has been used for “racist exclusion” and has caused “historical harm.” The AMA, one of the largest medical groups in the U.S., voted to adopt this policy during its annual meeting here.

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Pharmacists Applaud New Bionic Pancreas for Type 1 Diabetes

Drug Topics

The iLet Bionic Pancreas combines data from the Dexcom G6 CGM with different algorithms to deliver insulin throughout the day.

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Management of Clostridoides Difficile: A Focus on the Pharmacist's Role in the Care Continuum

Pharmacy Times

Patient education and counseling play a critical role in preventing C. difficile recurrence, and pharmacists are uniquely positioned to provide treatment recommendations, educate patients and health care providers, optimize transitions of care, and reduce the risk of recurrent CDI.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Merck's Keytruda aims for updated stomach cancer label with positive data

Fierce Pharma

Merck’s cancer star Keytruda could be on its way to an updated label in HER2-positive stomach cancer after showing it can stave off tumor progression in a combination study. | After scoring accelerated approval to treat HER2-positive stomach cancer in 2021, the drug has now shown it can stave off tumor progression in patients with PD-L1 positive tumors.

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Teens seeking addiction care unlikely to be offered standard medication

STAT

Adolescents who seek treatment for opioid addiction at an inpatient facility are more likely to be offered horseback riding than given full access to a common, highly effective addiction medication. According to a new research paper, just one out of every eight residential treatment facilities open to patients ages 16 or 17 offers full access to buprenorphine.

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Why Are Pharmacogenomics Not Fully Implemented in Health Care?

Drug Topics

A look at how the genetics-based research field can become more fully integrated in all areas of health care going forward.

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Have Children Truly Ever Been ‘Therapeutic Orphans?’

Pharmacy Times

Imposing the FDA on-label/off-label framework on administratively defined "children" resulted in a regulatory demand for pediatric studies that had no basis in clinical medicine, with the exception of the small group of preterm newborns.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Eli Lilly's Mounjaro is primed to surpass Novo Nordisk's popular diabetes and obesity duo: report

Fierce Pharma

In the battle for superiority in the field of next-gen diabetes and obesity treatments, Novo Nordisk holds the lead as the developer of the metabolism-regulating treatment semaglutide. | In the battle for diabetes and obesity superiority, Novo Nordisk holds a head start as the original developer of the metabolism-regulating treatment semaglutide. But Eli Lilly is quickly gaining ground and is primed to become the market leader with its GLP-1 treatment Mounjaro, according to GlobalData.

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The vast majority of Americans want to age in place. Assistive technologies are helping them pull it off

Fierce Healthcare

Over 90% of respondents to a recent U.S. News and World Report survey said their goal is to age in place. | More than 90% of respondents to a recent U.S. News and World Report survey said their goal is to age in place. A whopping 88% also reported that assistive or health-related technologies have improved their quality of life.

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Can Simulation Training Help Pharmacists be More Prepared for Emergencies?

Drug Topics

Over 90% of survey respondents said they believed emergency response simulation training should be required annually.

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Expert: Immunotherapies, Targeted Therapies Show Promise in Melanoma

Pharmacy Times

Heidi Finnes, PharmD, BCOP, FHOPA, director of clinical ambulatory pharmacy practice at Mayo Clinic, discussed updates in melanoma and the use of immunotherapies and targeted therapies.

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Game on, AbbVie. Roche's Columvi nabs FDA nod as 2nd bispecific for large B-cell lymphoma

Fierce Pharma

Less than a month after AbbVie and Genmab won FDA approval for Epkinly, Roche has crossed the finish line with its bispecific answer to large B-cell lymphoma. | Less than a month after AbbVie and Genmab won FDA approval for Epkinly, Roche has crossed the finish line with its bispecific answer to large B-cell lymphoma, though with a narrower label.

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Stanford Medicine launches initiative to advance responsible AI in healthcare

Fierce Healthcare

With the release of ChatGPT, what had long been science fiction became a reality, leaving healthcare wondering where medicine meets machine. | This week, Stanford Medicine and Stanford Institute for Human-Centered Artificial Intelligence (HAI) launched Responsible AI for Safe and Equitable Health (RAISE-Health) with the goal of addressing critical ethical and safety issues regarding the technology.

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Meeting Preview: McKesson ideaShare 2023

Drug Topics

Meet this year’s Pharmacy of the Year nominees and preview some of the sessions available at this year’s meeting.

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FDA Approves Supplemental New Drug Application To Expand Mavacamten Label for Obstructive Hypertrophic Cardiomyopathy

Pharmacy Times

VALOR HCM is the second study to show that mavacamten can significantly reduce symptoms of obstructive hypertrophic cardiomyopathy, which includes left ventricular outflow tract.

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Sanofi goes 'all in' on AI with new app to support company's manufacturing, R&D and more

Fierce Pharma

Sanofi is jumping on the artificial intelligence boat with a new app and a pledge to become “the first pharma company powered by artificial intelligence at scale.” | Sanofi's new app, plai, provides teams with a “360° view" to aid decision-making. The platform is one step in the company's digital transformation and goal to become the "first pharma powered by AI at scale.

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Digital health should brace for 'significant amount of churn' as hospitals reconsider COVID-era tech contracts

Fierce Healthcare

Digital health companies should brace for a shake-up as COVID-era contracts inked with hospitals will soon be up for renewal, according to the results of a recent survey. | Numerous digital health contracts signed by hospitals reacting to COVID-19 are nearing their conclusion, giving many providers a chance to reevaluate their options, a recent executive survey suggests.

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Contraceptives, Gender-Affirming Care, and Other Hot Topics for Pharmacists

Drug Topics

What is the state of OTC contraception, what’s next for IUDs, and why are so many transgender people denied care?

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AmerisourceBergen Corporate Partnerships Team Aims to Support, Guide Pharmacy Customers

Pharmacy Times

Claire Biermaas, president of Corporate Partnerships at AmerisourceBergen, discussed the Corporate Partnerships Team, which works closely with pharmacy customers to guide their processes and help execute their vision.

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Johnson & Johnson inks another Stelara patent settlement, this time with Alvotech and Teva

Fierce Pharma

Another biosimilar product copying Johnson & Johnson’s top-selling drug Stelara may enter the U.S. market without a patent infringement challenge by early 2025 thanks to a new settlement. | Following a deal with Amgen, J&J has granted Alvotech and Teva a license to launch their Stelara biosimilar no later than Feb. 21, 2025.

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Walgreens inks another deal for clinical trials business as CVS exits research recruitment

Fierce Healthcare

Retail pharmacy giant Walgreens inked another partnership to recruit participants for research as it continues to build out its clinical trials business. | Retail pharmacy giant Walgreens inked another partnership to recruit participants for research as it continues to build out its clinical trials business.

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Pharmacy Compounders Defend Semaglutide Compounding Amid Continued Shortages

Drug Topics

Novo Nordisk is the only company with FDA-approved products containing semaglutide.

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FDA Grants Accelerated Approval to Glofitamab-gxbm for Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Pharmacy Times

Glofitamab targets CD3, a protein found on the surface of immune T cells in patients with relapsed or refractory diffuse large B-cell lymphoma, and CD20, a healthy or malignant protein that lines the surfaces of B cells.

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Obesity impairs brain responses to nutrients, even after weight loss, study finds

STAT

Brain responses to nutrients in the gut are impaired in people with obesity, and that doesn’t change even after they lose weight through changes in diet, a new study finds, adding to mounting research showing the complexity and persistence of the biological effects of obesity. Using brain imaging, researchers saw that when people without obesity received nutrients, they experienced reduced activity in areas of the brain involved in food intake, suggesting the brain is signaling to them th

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Biogen refreshes board as chairman departs, adding a Langer while leaving 2 empty seats

Fierce Pharma

Biogen has taken a step to “significantly refresh” its board of directors, departing chair Stelios Papadopoulos, Ph.D., said. | Biogen has taken a step to “significantly refresh” its board of directors, departing chair Stelios Papadopoulos, Ph.D., said. But the reported romantic relationship between a new nominee and a departing member raises questions about one appointment.

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Recapping The First Two Days Of ASHP Summer Meetings 2023

Drug Topics

What stood out on Sunday and Monday at the 2023 ASHP Summer Meetings in Baltimore?

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New Therapies Show Significant Efficacy in Breast Cancer

Pharmacy Times

Both immunotherapies and targeted therapies are showing significant promise in these areas, offering patients new treatment options.

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