Tue.Mar 19, 2024

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Novavax COVID-19 Vaccine Shows Lasting Protection Against Delta Variant

Drug Topics

The biotechnology company’s recombinant spike protein-based vaccine demonstrated an efficacy of 88% after 40 days, 82% after 120 days, and 77% after 180 days during the PREVENT-19 trial.

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FDA Issues Paper on the Responsible Use of Artificial Intelligence in Medical Research

Pharmacy Times

The agency will focus on collaboration to protect public health; advancing regulatory approaches; developing standards, guidelines, and best practices; and supporting research that evaluates and monitors AI performance.

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Trending Sources

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Vaccines to Watch in 2024

Drug Topics

Moderna, Merck, and Pfizer-BioNTech are leading the charge with new vaccines for respiratory viruses in development.

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A study says intermittent fasting is making people drop dead. Oh, come on

STAT

The news is everywhere in my social news feeds this morning: A popular fad diet is apparently lethal, scientific research says. Specifically, a study found that caloric restriction, also known as intermittent fasting, has a 91% risk of death due to cardiovascular disease. Except scientific research doesn’t say that — and not only should you not be worried about this study, you shouldn’t be wasting brain glucose thinking about it.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Google's healthcare AI ambitions: New model for personal health coaching and next steps for gen AI

Fierce Healthcare

Google is doubling down on its ambitions for healthcare AI by exploring how generative AI can help clinicians in medical decision-making, understand lab and imaging information and provide con | Google is hyper-focused on generative AI in healthcare, pushing forward research to advance gen AI capabilities that can help clinicians in medical decision-making, understand lab and imaging information and provide consumers with personalized health insights based on their wearable data.

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Opinion: The evidence is clear: A liquid-only diet before a colonoscopy is unnecessary

STAT

Since colorectal cancer is on the rise in people younger than age 50, national guidelines have recently pushed the starting age for colorectal cancer screening down to 45. We need to spread the word. Yet we specialists continue to provide outdated and disproven recommendations on colonoscopy bowel preparation that make the process more difficult for the millions of patients who undergo colonoscopy every year: We tell them to adopt a clear liquid diet the day before their procedure.

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More Trending

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STAT+: As targeted radiation field heats up, AstraZeneca to pick up Fusion Pharmaceuticals in $2 billion deal

STAT

LONDON — AstraZeneca said Tuesday it would acquire Fusion Pharmaceuticals in a deal worth more than $2 billion, picking up a company focused on the booming area of targeted radiation therapies for cancer. AstraZeneca will pay $2 billion in cash upfront for Fusion, a price that at $21 a share is nearly double Fusion’s closing share price on Monday.

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Google Health, Stanford Medicine unveil open-access dataset of diverse dermatology images

Fierce Healthcare

Google Health unveiled an open-access dataset of real-world dermatology images in partnership with Stanford Medicine. | Thousands of people contributed their images of skin, hair and nail conditions to the Skin Condition Image Network (SCIN) for a diverse dataset reflecting various skin tones, ages, settings and condition severities.

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Riding GLP-1 wave, Novo Nordisk lays out $560M to boost drug production in China

Fierce Pharma

This year marks Novo Nordisk’s 30th anniversary in China, and it could also be the year the company's red-hot weight loss injection Wegovy (semaglutide) wins approval in the populous East Asian nat | 2024 marks Novo Nordisk’s 30th anniversary in China, and it could also be the year the Danish drugmaker’s red-hot weight loss injection Wegovy (semaglutide) wins approval in the populous East Asian nation.

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CDC releases field-tested guidance for hospital CEOs tackling their workers' mental health

Fierce Healthcare

The Centers for Disease Control and Prevention (CDC)’s campaign against healthcare worker burnout took a step forward this week with the release of a new instructional guide for executive-level hos | The free resource was developed alongside the Dr. Lorna Breen Heroes' Foundation and informed by a six-month, six-hospital pilot across CommonSpirit Health facilities.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: UnitedHealth appears to be upping loan offers to providers, after Change cyberattack

STAT

UnitedHealth Group appears to be offering some providers more substantial loans in the wake of the cyberattack on Change Healthcare, according to three doctors who each saw their advances increase up to seven figures. The apparent change comes as hospitals, doctors, and lobbying groups have for weeks complained about low offers from the company, in some cases less than 1% of their typical weekly billing.

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Elevance Health to acquire Kroger Specialty Pharmacy

Fierce Healthcare

Elevance Health has inked a deal to acquire Kroger Specialty Pharmacy. | The grocery chain announced Monday that an agreement is in place, saying it's expected to close in the back half of 2024 pending regulatory approvals.

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STAT+: Q&A: Mark Parrino says it’s time to ‘completely re-examine’ methadone treatment for opioid addiction

STAT

Nobody has made more of an impact on methadone treatment than Mark Parrino. For decades, he’s served as the founder and president of the American Association for the Treatment of Opioid Dependence, a nationwide advocacy group representing methadone clinics. Before AATOD, he ran a statewide advocacy group in New York, having made the jump to politics and policy after working as a clinic director and, before that, as an addiction counselor.

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Improving patient engagement and drug development through AI and enhanced medical affairs roles

pharmaphorum

Learn how AI and enhanced medical affairs roles are transforming the landscape of drug development and patient engagement in the health industry. Explore the benefits and advancements in this exciting field.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: In small study, baby aspirin cuts fat buildup in liver disease patients

STAT

Low-dose aspirin led to a reduction in liver fat among patients with metabolic-associated liver disease, a small study out of Boston found.  The clinical trial, led by Tracey Simon of Massachusetts General Hospital and Harvard Medical School, compared two groups of patients with metabolic dysfunction-associated steatotic liver disease, or MASLD.

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The unmentionables: Challenging inequalities in women’s health

pharmaphorum

As Women’s History Month continues, pharmaphorum web editor Nicole Raleigh welcomed a group of expert individuals onto the podcast to discuss not just the inequalities in women’s health, but female leaders within life sciences, too.

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Gilead CEO Daniel O'Day collects 5% pay raise to $22.6M, his largest compensation package in years

Fierce Pharma

After a year marked by Gilead's oncology push and an ongoing focus on CAR-T therapies, CEO Daniel O’Day collected his largest total compensation package since the year he arrived at the Califo | The CEO collected his highest total compensation package since his first year in the role in 2019.

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Managing the challenges and embracing the opportunities of EU-wide HTA

pharmaphorum

Discover the key strategies for managing the challenges and embracing the opportunities of EU-wide Health Technology Assessment (HTA) in partnership with the European Medicines Agency (EMA) and prospective market authorisation holders (pMAHs).

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In his final full year as AbbVie's CEO, Richard Gonzalez collects $25.7M in total pay

Fierce Pharma

Guiding AbbVie through an extraordinary decade-plus, riding the success of juggernaut inflammatory disease drug Humira and softening the landing upon its decline, Richard Gonzalez continues to reap | In his final full year as AbbVie’s CEO, Richard Gonzalez pulled down a compensation package worth $25.7 million, according to the company’s proxy filing.

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How long does a UTI last?

The Checkup by Singlecare

A urinary tract infection (UTI) can cause significant discomfort, from a nagging ache in your lower abdomen to a burning sensation that makes urinating feel excruciating. A UTI is most often caused by bacteria in the colon that enter the urinary system, a UTI can affect the urethra, bladder, kidneys, or ureters. Risk factors include being female, engaging in sexual intercourse, having a history of UTIs, using certain types of birth control (like diaphragms or spermicide), and decreasing estrogen

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STAT+: Pharmalittle: We’re reading about an AstraZeneca deal, a WHO pandemic pact, and more

STAT

Rise and shine, everyone, another busy day is on the way. Already, the official mascots are racing about the Pharmalot campus in search of breakfast and a steady stream of traffic can be heard nearby. As for us, we are engaged in the usual rituals, starting with brewing cups of stimulation. Our choice today is salted caramel, a veritable whiff of the Jersey shore.

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WuXi AppTec still sees sales growing and expansions rolling in 2024 despite concerns over US biosecurity bill

Fierce Pharma

In moments of great uncertainty, sometimes the best approach is to just press on. | CDMO WuXi AppTec reported solid performance in 2023 and expects good things for the coming year, too. Still, the Chinese contract manufacturer finds itself embroiled in a national security crackdown in the U.S., where a proposed law threatens to upend WuXi's business.

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Match Day 2024: Record number of applicants, residency positions

Fierce Healthcare

The upcoming crop of soon-to-be physicians learned on Friday where they would spend their residencies. Match Day 2024 saw record-high applicants and residency positions offered. | The upcoming crop of soon-to-be physicians learned on Friday where they would spend their residencies. Match Day 2024 saw record-high applicants and residency positions offered.

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Pharmacist Education, Knowledge Key to Fostering Biosimilar Adoption

Drug Topics

Despite the significant growth of biosimilars, their adoption across various therapeutic areas has remained slow.

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PAP 2024: John Hoffman Discusses the Health Equity Spotlight Panel

Pharmaceutical Commerce

In an interview with Pharma Commerce Associate Editor Don Tracy, John Hoffman, Principal, Advocate for Success, LLC talks about his 'Health Equity Spotlight' panel and advocacy accomplishments.

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IFF, after brief leadership stint under Merck's Frank Clyburn, pawns off pharma solutions business for $2.85B

Fierce Pharma

After a two-year stint under Merck & Co. veteran Frank Clyburn, New York’s International Flavors & Fragrances (IFF) is stripping away a major component of its healthcare persona. | New York's IFF—which dabbles in food, beverage, beauty and pharmaceutical supply chains, among others—has agreed to sell its pharma solutions business to French plant-based ingredient maker Roquette for up to $2.85 billion.

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Wellness Trends Worth Watching Among Younger Patients

Digital Pharmacist

Younger patients are already beginning to dictate the course of modern healthcare, yet they are rarely the focus of pharmacies’ marketing efforts. Their focus on holistic health and lifestyle-based solutions have contributed to an emphasis on mental health and to recent upticks in organic and wellness trends. Pharmacies can take a long-term approach to marketing by closely looking at who their younger patients are and what they need from their local pharmacy.

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Novartis acquisition to address inflammation-driven diseases

European Pharmaceutical Review

Under a new deal, Novartis has agreed to acquire US-based biopharma company IFM Therapeutics, for a total of up to $835 million. As part of this new agreement, Novartis has exercised its option to acquire all outstanding capital stock of IFM Due, a subsidiary company of IFM. Therefore, under the acquisition, Novartis has full rights to IFM Due’s portfolio of small molecule Stimulator of Interferon Genes (STING) antagonists, IFM confirmed.

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Takeda's Iclusig wins first-line FDA nod to treat rare Philadelphia chromosome-positive ALL

Fierce Pharma

Twelve years after Takeda's Iclusig (ponatinib) earned a restricted FDA approval to treat certain patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL), the U.S. | Twelve years after Takeda's Iclusig earned a restricted FDA approval to treat certain patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL), the U.S. regulator has signed off on a wider use.

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Bayer cues up filings for rival to Astellas’ menopause drug

pharmaphorum

New phase 3 data sets up filings for Bayer's non-hormonal menopause symptom treatment elinzanetant and a challenge to Astellas’ first-to-market Veozah

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Burnout at Work: How to Manage Pharmacy Fatigue in 2024

PioneerRx

Pharmacy work is demanding. One minute you’re at the drive thru. The next, you’re answering phone calls or submitting vaccination claims. A day in the pharmacy.

Vaccines 105
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FDA Approves Expanded Indications for Spesolimab-sbzo Injection for the Treatment of Generalized Pustular Psoriasis

Pharmacy Times

To date, this is the only targeted therapy indicated for the treatment of generalized pustular psoriasis.

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AZ agrees $2bn deal to buy radiopharma firm Fusion

pharmaphorum

AstraZeneca upgrades its radiopharma alliance with Fusion Pharma, opting to buy the biotech outright in a deal worth around $2 billion

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Wegovy and Zepbound get primetime treatment

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, everyone. Damian here with a look at a pioneering new gene therapy, the plight of WuXi AppTec, and a rough month for biotech’s neuroscience renaissance.

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