Thu.Oct 26, 2023

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Reproducibility of Consecutive CGM Results in Cystic Fibrosis-Related Diabetes

Drug Topics

Researchers assessed the reproducibility of at-home CGM acquisitions with mixed meal tolerance tests among patients with CF-related diabetes who were not treated with insulin.

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Why Data Point to Hospital At-Home Care as Next Evolution of Clinical Medicine

Pharmacy Times

With health systems undergoing a necessary reevaluation of how they allocate their funding into the future, initial data support the need for them to offer a hospital-at-home option for patients they serve.

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Industry Voices—The beginning of the end for Alzheimer’s Dementia?

Fierce Healthcare

The approval of Leqembi by the Food and Drug Administration marks an exciting turning point for Alzheimer’s disease. | The approval of Leqembi by the FDA marks an exciting turning point for Alzheimer’s disease. There are big questions around costs, access, risk and efficacy in certain populations. The most urgent, overarching question is: How can we find patients who will benefit from the drug before their condition progresses outside of the treatment window?

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Meeting the Challenges in Behavioral Health Care With Hybrid Pharmacy Approach

Pharmacy Times

The hybrid pharmacy model represents a significant step forward in providing the best possible care for individuals struggling with behavioral health conditions, ultimately improving their outcomes and overall well-being.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Discovery that chimpanzees go through menopause challenges ‘grandmother hypothesis’

STAT

Chimpanzees — they’re just like us. Female chimps, it turns out, go through menopause, and go on to live long (and, one hopes, fulfilling) lives afterward. A new paper published today in Science describes the discovery of the onset of menopause in a community of wild chimpanzees around the age of 50, with an overall decline in fertility starting at age 30.

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CVS, Mayo Clinic, Spark Capital back Abridge's $30M round to scale up generative AI in healthcare

Fierce Healthcare

Abridge, a startup that developed artificial intelligence-based documentation solutions for healthcare, has seen rapid growth in the past year, propelled by a "tornado of tailwinds," according to c | Abridge, a startup that developed artificial intelligence-based documentation solutions for healthcare, has seen rapid growth in the past year, propelled by a "tornado of tailwinds," according to company CEO Shivdev Rao, M.D.

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Expert: The Growth of the 340B Drug Pricing Program Has Influenced the Landscape of Cancer Care

Pharmacy Times

The vice president of pharmacy operations at American Oncology Network discusses the 340B Drug Pricing Program and its growth and impact on community oncology.

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One-third of Americans burdened by medical debt: study

Fierce Healthcare

Insurance coverage often fails to help Americans avoid medical debt, a new survey from the Commonwealth Fund revealed. | Even with health insurance, people are feeling the effects of high medical costs, often cutting back on necessities or delaying care. A new survey shows half of Americans struggle to avoid their healthcare.

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FDA Approves Vosoritide for Children With Achondroplasia

Pharmacy Times

Vosoritide is a daily injection for children with achondroplasia who have open epiphyses, given under the skin and administered by a caregiver.

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Increased Risk for Lung Cancer May Be Linked With Metabolic Syndrome

Drug Topics

Study results suggest an association between lung cancer, low high-density lipoprotein cholesterol, waist circumference, and glycated hemoglobin.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Subcutaneous Lecanemab Found Equally Effective as IV Version in Alzheimer Disease Treatment

Pharmacy Times

A weekly dose of injectable lecanemab-irmb (Leqembi) could allow patients with Alzheimer disease to receive the drug at home instead of visiting an infusion center twice per month.

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New multispecialty advocacy group wants to protect independent practices from hospitals' buyouts

Fierce Healthcare

A new national, multispecialty advocacy organization representing independent practices launched last week. | The American Independent Medical Practice Association says it is the first advocacy organization of its kind focused on supporting private medicine across specialties. It is made up of 5,000 physicians collectively treating 10 million U.S. patients.

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Opinion: Want to end historic health care strikes? Fix a broken, outdated reimbursement model

STAT

History was made this month as more than 75,000 workers staged the largest health care strike to ever take place in the United States. The Kaiser strike is over, for now, but there is no clear resolution in place, and other strikes are still under way or on the horizon. At the same time, we are in the midst of a nurse staffing crisis. About 800,000 nurses plan to leave the workforce by 2027, and more than half of newly graduated nurses are leaving the profession within two years.

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Novartis claims ex-staffer jumped to Takeda with 'thousands' of sensitive files

Fierce Pharma

Novartis believes a former employee of its Egyptian affiliate made off with thousands of files before jumping ship to Takeda. | Novartis believes a former employee of its Egyptian affiliate made off with thousands of files before jumping ship to Takeda. Now, the Swiss pharma giant wants a peek at Takeda’s business records to find out whether its confidential information has been used improperly.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Why Price Transparency is Important for Consumers in Veterinary Medicine

Drug Topics

Jason Reed, PharmD, Senior Director of Product Management at FTB Vella, discusses the importance of drug price transparency for both consumers and veterinarians.

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FDA Approves Vamorolone for Treatment of Duchenne Muscular Dystrophy in Patients Aged 2 Years and Older

Pharmacy Times

The drug’s mode of action is different than other types of corticosteroids because it’s based in the differential effects on glucocorticoid and mineralocorticoid receptors.

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Eisai, Biogen's injectable Leqembi clears toxic protein in Alzheimer's disease. What about safety?

Fierce Pharma

With concerns growing over the burden Leqembi could impose on healthcare infrastructure, Eisai and Biogen have trotted out data for an under-the-skin version of the Alzheimer’s disease drug that ma | Eisai and Biogen have trotted out data for a subcutaneous version of the Alzheimer’s disease drug Leqembi. The self-injected version showed an encouraging efficacy result but a seemingly increased risk of ARIA, which analysts said shouldn't be too much of a concern.

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Embracing Opportunities: Reflections and Advice From a Fourth-Year Student

Pharmacy Times

From finding mentors to maintaining a balanced lifestyle, these insights will empower students to navigate the ever-evolving world of pharmacy.

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Employers should be finding ways to invest in workers' vitality, Cigna says. Here's why

Fierce Healthcare

Despite reporting slightly worse physical and mental health, Americans are feeling more optimistic about their vitality, according to a new analysis from the Cigna Group, which concludes that emplo | Despite reporting slightly worse physical and mental health, Americans are feeling more optimistic about their vitality, according to a new analysis from the Cigna Group, which concludes that employers can play a key role in addressing these challenges.

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STAT+: FDA approves Lilly ulcerative colitis treatment with a new approach to tamping down inflammation

STAT

The Food and Drug Administration on Thursday approved an Eli Lilly drug that takes a new approach to treating ulcerative colitis, a chronic inflammatory disease that can cause intense gastrointestinal pain and distress. The therapy, dubbed Omvoh, is an antibody that blocks IL-23p19, an immune signaling molecule that plays a key role in sustaining the disease.

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Best Cost Isn’t Always the Lowest Cost: How to Drive Strategic Pharmacy Purchasing Decisions

Drug Topics

Unlock pharmacy success with our in-depth White Paper. Explore strategies to overcome rising operational costs, tackle DIR fee challenges and understand that best cost isn't always the lowest. Gain sights into vendor management, primary vendor, GPO and buying group compliance, maximizing rebates and more to optimize your pharmacy’s financial health.

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Tirzepatide With Diet and Exercise Could Boost Weight Loss

Pharmacy Times

Long lasting weight reduction was reported in individuals that were treated with tirzepatide with diet and exercise, compared to placebo.

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The Ultimate Guide to Achieving DSCSA Compliance for Pharmacies

Drug Topics

Unlock DSCSA compliance insights with SureCost's latest white paper where it navigates the complex landscape of regulations, such as the upcoming shift to T2 data. Learn about traceable items, exemptions and importance of data centralization. Dive into the impact of drug shortages and the risks of non-compliance. Discover the power of SureCost in streamlining DSCSA compliance processes and maximizing efficiency.

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Pfizer’s twice daily pill for obesity hopes to rival Wegovy and Mounjaro

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, all. Damian here with a glimpse at the next big thing in Alzheimer’s disease, Pfizer’s future in treating obesity, and the downstream effects of a biotech slump.

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Drug Transparency Can Help Patients Make Better, More Informed Decisions

Drug Topics

Lathe Bigler, Vice President of Clinical Network Services at FDB and General Manager at FDB Vela, discusses drug transparency and why it's important for patients to shop around for their prescriptions.

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Merck raises revenue guidance thanks to a surprising bump from COVID-19 pill Lagevrio

Fierce Pharma

It’s been grounded in Europe and reduced to irrelevancy in the U.S., but Merck’s COVID-19 pill Lagevrio somehow remains a force. | It’s been grounded in Europe and reduced to irrelevancy in the U.S., but Merck’s COVID-19 pill Lagevrio somehow remains a force. The antiviral treatment racked up sales of $640 million in the third quarter, shocking analysts who figured it would generate $120 million.

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What Smoking Cessation Strategies are Most Effective for Pregnant Women?

Drug Topics

Researchers said the most effective smoking cessation method was counseling, which could be boosted with financial incentives and doctor/nurse feedback interventions.

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Transition From Analog to Digital Has Allowed Pharmacists to Explore New Opportunities

Pharmacy Times

Craig Sastic, PharmD, MBA, BCPS, discussed how he has seen the pharmacy field change throughout his career.

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Future Preventive Strategies to Reduce RSV Burden in Pediatric Health Care

Drug Topics

Recognizing the challenges and needs associated with combating and preventing RSV may help reduce health care and patient burdens.

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6 supplements that boost testosterone

The Checkup by Singlecare

Testosterone is a hormone produced by the testicles that affects many types of bodily functions in men, including the development of the reproductive system, the building of lean muscle mass and red blood cells, and healthy sexual functioning. An insufficient amount of testosterone is often called male hypogonadism or “low T.” There are many causes of low testosterone levels , from simple aging to serious illness to chronic health conditions like obesity and diabetes.

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Bristol Myers' incoming CEO plots turnaround for struggling new launches

Fierce Pharma

On outgoing chief executive Giovanni Caforio’s last earnings call, Bristol Myers Squibb had some tough questions to answer about a roster of underperforming new products. | On outgoing chief executive Giovanni Caforio’s last earnings call, Bristol Myers Squibb had some tough questions to answer about a roster of underperforming new products. But according to CEO-elect Chris Boerner, it’s a question of “when, not if” those drugs rise to meet expectations.

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Listen: ESMO highlights, Roivant’s big deal, & biotech VC on the rise

STAT

How do cancer drugs work? What makes biotech stocks go up? And why are venture capitalists so optimistic? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. Our colleague Andrew Joseph joins us to explain the decades-old cancer-treating technology that had its star turn at this week’s big oncology conference in Europe.

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Takeda takes $770M in write-downs after Alofisel flop, Exkivity withdrawal decision

Fierce Pharma

After one Takeda drug flunked a phase 3 trial and as the company pulls another from the market, the drugmaker is taking some hefty impairment charges. | The write-downs were attributed to stem cell Alofisel's recent flunk in a phase 3 trial in Crohn's disease fistulas, plus the withdrawal of cancer med Exkivity worldwide. Takeda also cut its profit forecast for the year by a sizable amount.

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CVS and Walgreens Walkouts: What Independent Pharmacies Should Know

Digital Pharmacist

In recent weeks, the pharmacy industry has been shaken up as staff walkouts at CVS and Walgreens captured the attention of pharmacy teams and patients alike. These walkouts have left many curious about the reasons behind them and what implications these events may have on the future of the pharmacy profession. By understanding what led retail pharmacy team members to take these drastic actions, we can look at what independent pharmacies can do to avoid similar issues and also how independents ca