Fri.Jul 28, 2023

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Pfizer's New Migraine Treatment Now Available in US Pharmacies: What You Need to Know

Drug Topics

Zavegepant (Zavzpret) is the first and only calcitonin gene-related peptide (CGRP) receptor antagonist nasal spray approved by the FDA for acute migraine treatment in adults.

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The Price of Avoiding Death at All Costs Is Steep

Pharmacy Times

Author of the book The Journey’s End discusses how extending life at all costs takes away time that patients could be spending with their families during the last moments of their life.

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HPV Vaccination Rates Could Improve With Increased Reimbursement

Drug Topics

According to the CDC, HPV is the most commonly sexually transmitted infection in the US, with a prevalence of 45.2% of men and 39.9% of women aged 18-59 in 2013-2014.

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Tirzepatide Demonstrates Significant Weight Loss Compared to Placebo

Pharmacy Times

A new study indicates that adults with obesity or who are overweight with weight-related comorbidities can help manage their weight with lifestyle changes in conjunction with specified treatment.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Skin Cancer Screening Not Enough to Solve Racial Disparities in Melanoma Diagnosis

Drug Topics

A recent study determined over 12,000 screenings would need to be done to identify 1 case of melanoma in racial and ethnic minority populations.

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Intravenous Immunoglobulin Effective Controlling Neuromuscular Disease in Patients with Cancer Treated with Immune Checkpoint Inhibitors

Pharmacy Times

It was previously undetermined whether the combination of IVIG and ICI would lead to patient complications or reduced efficacy of the cancer treatment, but 2 successful case reports dispel that belief.

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Cap on Out-of-Pocket Insulin Costs in Inflation Reduction Act Increased Prescription Fills

Pharmacy Times

Thousands more people filled their insulin prescriptions following the introduction of the cap in January 2023, especially compared to those who were not enrolled in Medicare, a new study finds.

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His book on the opioid crisis flopped in 2003. It now has a new life on Netflix

STAT

A new Netflix TV show about the origins and consequences of the opioid epidemic is coming to the small screen. The show, “Painkiller,” is a fictional story based on real events that transpired around the Sackler family, Purdue Pharma, and the marketing and distribution of their drug, OxyContin. It adds to the growing list of television shows and movies around America’s opioid crisis, including Netflix’s own “The Pharmacist,” Hulu’s “Dopesic

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Community Pharmacists and Technicians: Impacting Public Health One Service at a Time

Pharmacy Times

Community-based pharmacy services are reaching new heights as pharmacists and pharmacy technicians are able to have a larger impact on patient care than ever before.

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Biogen, amid layoffs, ponies up $7.3B for rare disease specialist Reata and potential blockbuster Skyclarys

Fierce Pharma

On Monday during a quarterly earnings call, when Biogen CEO Chris Viehbacher was asked about the company’s potential to execute M&A, he randomly offered “we’ve got, I think, about $7.3 billion | Biogen has revealed a proposal to acquire Reata Pharmaceuticals for $7.3 billion. The Texas-based rare disease specialist brings newly approved Skyclarys, the first treatment for the neurologic disorder Friedreich’s ataxia with peak sales potential of $1.5 billion.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Second OTC Opioid Overdose Reversal Medication Approved by FDA

Pharmacy Times

The approval of RiVive naloxone hydrochloride nasal spray for nonprescription use provides another tool to help quickly reverse the effects of opioid overdose.

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Opinion: Doctors in states that ban abortion can still refer patients elsewhere. Why are so few doing that?

STAT

For now, abortion remains accessible even in states where it’s banned — at least for those who know where to look. It’s still legal in two-thirds of the country, and numerous websites explain how to order medications from international pharmacies to end early pregnancies at home. But not all patients have equal access to reliable information.

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Menstrual Migraines: Overview, Treatment, and Prevention

Pharmacy Times

Pharmacists play a key role in migraine management, therefore, awareness of menstrual migraine-specific prophylaxis is important.

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AHA, BCBSA urge CMS to ditch 'conflicting' requirements in prior authorization reform proposal

Fierce Healthcare

Lobbying groups representing different camps of the healthcare industry have come together to urge the Centers for Medicare & Medicaid Service (CMS) to reconsider “conflicting regulatory propos | The American Hospital Association, American Medical Association and Blue Cross Blue Shield Association penned a joint letter highlighting "conflicting" prior authorization electronic standards and workflows they say will bring industry confusion and unnecessary burden.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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13 ways to raise your blood pressure

The Checkup by Singlecare

When your healthcare provider places the blood pressure cuff around your arm, you likely hope you won’t have high blood pressure. Hypertension is a common medical condition, but did you know there’s also a possibility your blood pressure could be too low? Turns out, a lot can be revealed as that cuff tightens around your biceps. Blood pressure is a measure of heart and vascular health, specifically the force of blood force flowing through blood vessels.

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'The danger is great and growing': Healthcare experts call on industry to reduce the risks of nuclear war

Fierce Healthcare

The time is now 90 seconds to midnight, according to the Doomsday Clock, which scientists use to estimate how close humanity might be to blowing itself up with nuclear weapons. | The world hasn't been this close to nuclear war since the Cold War, say experts. Editors of prestigious medical journals sound a call to disarm.

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AstraZeneca forecasts stronger China sales as CEO tries to clear the air on spinoff report

Fierce Pharma

Is AstraZeneca planning to peel off its China business? By CEO Pascal Soriot’s response to that question, it may only a contingency plan. | Is AstraZeneca planning to peel off its China business? By CEO Pascal Soriot’s response to that question, it may only be a contingency plan.

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AI, nurses protesting, another hospital shooting—Stakeholders debate how to make hospitals safe

Fierce Healthcare

This week, a visitor opened fire at Legacy Good Samaritan Medical Center in Portland, killing a security guard and injuring a nurse. | Following increases in both aggression towards nurses and mass shootings, stakeholders are debating whether new tech or old solutions can make a difference.

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STAT+: AstraZeneca buys early-stage gene therapies from Pfizer in boon for struggling field

STAT

AstraZeneca said Friday it will buy up a group of early-stage gene therapies from Pfizer, bucking a trend of drugmakers axing programs and exiting a field that had once captured the imagination — and checkbooks — of many pharmaceutical executives. AstraZeneca will pay Pfizer up to $1 billion plus royalties for the portfolio of treatments, none of which has entered clinical trials yet.

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Discharge medication errors in England could be cut by around 40%, study finds

Hospital Pharmacy Europe

Medication errors when people go into or are discharged from hospital in England could be reduced by nearly 40% with the introduction of new digital information standards being rolled out this year, say researchers. Analysis by a team at the University of Manchester found that medication errors would be cut from 1.8 million to 1.1 million (39%) by the easier sharing of information across hospital and GP systems.

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Teva CEO Francis poaches business development head Angus Grant from BeiGene

Fierce Pharma

Teva’s CEO Richard Francis is adding to his constellation of new executives with a fresh business development hire from BeiGene. | Teva has enlisted BeiGene's Angus Grant, Ph.D, as its EVP of business development, the Israeli-American generics giant announced Friday. It was during Grant's tenure as chief business executive that BeiGene signed the high-profile PD-1 and TIGIT pacts with Novartis.

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Message from the Chair: Why Attend the 2023 ISPE Pharma 4.0™ & Aseptic Conference

ISPE

Message from the Chair: Why Attend the 2023 ISPE Pharma 4.0™ & Aseptic Conference Trudy Patterson Fri, 07/28/2023 - 10:40 iSpeak Blog iSpeak Message from the Chair: Why Attend the 2023 ISPE Pharma 4.0™ & Aseptic Conference Jörg Zimmermann 28 July 2023 I have been active in ISPE for many, many years, but when I attended my first ISPE Pharma 4.0™ and Annex 1 Conference in Manchester back in 2019, I was surprised by how few people I knew.

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Opinion: Many immigrants are ineligible for important U.S. maternal health initiatives

STAT

In the U.S., about 16%  of Black birthing people are immigrants. But even as the federal government and states take steps to improve national maternal health, particularly among Black birthing parents, many immigrant parents are left out of new policy initiatives to provide access to postpartum care. Worsening maternal health in the U.S. and stark racial disparities have set in motion new policy efforts to increase access to postpartum care during the year following childbirth.

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Message from the Chair: Why Attend the 2023 ISPE Pharma 4.0™ & Annex 1 Conference

ISPE

Message from the Chair: Why Attend the 2023 ISPE Pharma 4.0™ & Annex 1 Conference Trudy Patterson Fri, 07/28/2023 - 10:40 iSpeak Blog iSpeak Message from the Chair: Why Attend the 2023 ISPE Pharma 4.0™ & Annex 1 Conference Jörg Zimmermann 28 July 2023 I have been active in ISPE for many, many years, but when I attended my first ISPE Pharma 4.0™ and Annex 1 Conference in Manchester back in 2019, I was surprised by how few people I knew.

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STAT+: Biogen to acquire Reata Pharmaceuticals in $7 billion deal

STAT

Biogen on Friday said it would acquire Reata Pharmaceuticals, the maker of an approved therapy for a rare neurological condition, in a deal worth $7.3 billion. The transaction price of $172.50 per share is a nearly 60% premium from Reata’s share price at Thursday’s close. The deal is expected to close by the end of the year. Reata, based in Plano, Texas, won its first approval in February for a drug that treats Friedreich’s ataxia.

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Rite Aid shares progress on sustainability efforts

Drug Store News

​​​​​​​Rite Aid shared its progress across its four key pillars, focused on areas such as environmental sustainability, responsible sourcing, employee benefits and more.

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STAT+: Pharmalittle: Pharma hopes reformulated drugs will skirt Medicare negotiations; Biogen to acquire Reata for $7.3 billion

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is rather modest. We plan to take in a football match, catch up on our reading, and promenade with the official mascots. And if time permits, we may hold a listening party, where the rotation would include this , this , this and this.

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Sanofi posts 'solid' Q2 performance with 3 launches underway and Dupixent headed for €10B mark

Fierce Pharma

Even as Aubagio generics chip away at Sanofi’s sales in the U.S.—and soon, in Europe, too—the company is relying on a trio of new medicines to bring home at least €5 billion in peak sales in the co | As Aubagio generics chip away at Sanofi’s sales in the U.S.—and soon, in Europe, too—the company is relying on a trio of new medicines to bring home at least €5 billion in peak sales in the coming years.

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A Surge in Mpox Cases Could Occur This Summer

Drug Topics

Demetre Daskalakis, MD, MPH, urged those in the LGBTQ+ community to get fully vaccinated against the disease.

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Novel pill could aid postpartum depression symptoms

European Pharmaceutical Review

Publication of results of the Phase III SKYLARK study “is a pinnacle moment in treating postpartum depression ( PDD ),” stated Dr Kristina M Deligiannidis, Professor at the Institute of Behavioral Science at the Feinstein Institutes, the trial’s principal investigator, lead author of the paper. The study investigated oral 50mg, 14-day neuroactive steroid zuranolone pill as a treatment for perinatal or postpartum depression.

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STAT+: With profitability in sight, Talkspace is budding into a digital health success story

STAT

Virtual mental health company Talkspace on Thursday added to its run of promising earnings reports, with the once-embattled company continuing to project it would break even by early 2024. Analyst groups like William Blair nodded along approvingly at Talkspace’s latest “step in the right direction” as the company, whose main business is providing therapy over text chat and audio and video connections, beat expectations by posting $35.6 million in revenue, for a $4.7 million

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Vaccination Amid Limited RSV Therapy Options for Adults

Pharmacy Times

Medical experts discuss the lack of RSV treatment leading to the importance of immunization.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.  That’s right. Send us your changes, and we’ll find a home for them.  Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Brain Health Watch

Pharmacy Times

PT staff discusses health outcomes involving SABI, reduced vascular function, and OBA.

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