Drug Topics

DECEMBER 5, 2023

The CDC first released opioid prescribing guidelines in 2016.

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STAT

DECEMBER 5, 2023

WASHINGTON — Pfizer has decided to leave the Biotechnology Innovation Organization, according to two sources familiar with the decision. The departure is a blow to BIO, which represents members ranging from small biotech startups to massive pharmaceutical companies. The group on Tuesday announced its new CEO, rare disease advocate and biotech executive John Crowley.

Pharmaceutical Companies 145

Pharmaceutical Companies Pharmaceutical Companies 145

Drug Topics

DECEMBER 5, 2023

Updated guidance from the United States Preventive Services Task Force advises against low-dose aspirin use as a primary prevention of atherosclerotic cardiovascular disease in certain populations who have bleeding risks.

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STAT

DECEMBER 5, 2023

CVS Health is promising to simplify how its pharmacies get paid for drugs. But that doesn’t mean the drugs will get cheaper. The country’s biggest pharmacy chain said it’s switching to a system where pharmacy benefit managers, employers, and other insurers pay for drugs based on the cost of the drug plus a set markup and dispensing fee.

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Insurance 145

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

Pharmacy Times

DECEMBER 5, 2023

In the first-line setting, inavolisib plus palbociclib and fulvestrant improved PFS in patients with HR-positive breast cancers; however, further research is needed to understand the trends in OS.

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STAT

DECEMBER 5, 2023

Eight months into his tenure, Johnson & Johnson’s R&D chief is putting a big emphasis on medicines for cancer, treatment-resistant depression, and autoimmune disease. To sharpen that focus, R&D chief John Reed told STAT that the company is de-emphasizing two areas that have been mainstays for the drug and medical device giant: infectious disease and vaccines, as well as medicines targeting kidney disease and rare eye conditions.

Vaccines 145

Vaccines 145

STAT

DECEMBER 5, 2023

Here are two things that are true. The world needs more effective flu vaccines. And pharmaceutical companies that learned of the vaccine-making power of the messenger RNA platform during the Covid-19 pandemic need new markets for their technology.

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Vaccines Pharmaceutical Companies Pharmaceutical Companies 145

Fierce Healthcare

DECEMBER 5, 2023

Nonprofit hospitals will continue to operate under a cloud of labor supply shortages and “pressured” margins into 2024, setting the coming 12 months up as another “make or break year” for the secto | Fitch Ratings' pessimistic 2024 outlook highlighted labor shortages, an uptick in union activity and potential second year of debt service covenant violations.

Hospitals 133

Hospitals 133

STAT

DECEMBER 5, 2023

The concept of fetal surgery captures the imagination when, from time to time, it makes the headlines. Few pregnant mothers will need the assistance of fetal medicine specialists; fewer still will need a fetal surgeon to save their children. But it can offer parents-to-be a sense of hope: In the appropriate circumstances, doctors may be able to help before the child is even born.

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Pharmacy Times

DECEMBER 5, 2023

Chia seeds are a nutrient dense product that are rich in fiber and omega-3 fatty acids, and could have a hypocholesterolemic effect when ingested.

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Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

FDA

STAT

DECEMBER 5, 2023

WASHINGTON — The Biotechnology Innovation Organization has chosen longtime biotech executive and rare disease advocate John Crowley as its new CEO, the organization announced Tuesday. Crowley came to biotech when his children were diagnosed with a rare genetic neuromuscular disease. He started working at Bristol-Myers Squibb, and started Novazyme, which was eventually successful in creating an enzyme replacement therapy for Pompe disease.

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Pharmacy Times

DECEMBER 5, 2023

Patients enrolled in the study had substantial absolute risks and elevated relative risks, suggesting that AKs may be a clinical marker of UV exposure and increased skin cancer risk.

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Fierce Healthcare

DECEMBER 5, 2023

Blue Shield of California members will no longer be covered across 17 Adventist Health hospitals, the hospital system recently announced. | Blue Shield of California and Adventist Health were unable to reach a new contract agreement, leaving members without coverage since Dec. 1. The hospital system says they remain open to future discussions.

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Hospitals 124

Fierce Pharma

DECEMBER 5, 2023

As Johnson & Johnson places a magnifying glass on its pharmaceutical business, the focus for the remainder of the decade rests on the shoulders of some 25 new and upcoming drugs.

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Pharmacy Management Software

STAT

DECEMBER 5, 2023

Biotech startup ReNAgade Therapeutics is cutting staff just seven months after raising the largest Series A round in the industry this year. ReNAgade launched in May with hopes of becoming a one-stop shop for medicines targeting RNA, the genetic blueprints that cells use to make proteins instrumental in numerous diseases. These types of medicines are in high demand following the advent of mRNA vaccines for Covid and RNA-silencing therapies made by companies like Alnylam Pharmaceuticals.

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Vaccines 124

Drug Topics

DECEMBER 5, 2023

A poster presented at ASHP Midyear 2023 highlighted the positive impact of including pharmacists in the care of postpartum women at risk of persistently elevated blood pressure (BP), particularly in cases of portopulmonary hypertension (PPHTN).

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Pharmacy Times

DECEMBER 5, 2023

The study authors note that increasing education, implementing online services, and removing stigma can help improve the uptake of PrEP in this population.

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Drug Topics

DECEMBER 5, 2023

According to a poster abstract presented at the ASHP Midyear Clinical Meeting & Exhibition, specialty pharmacy services were used for a variety of conditions that have been reported in adult populations.

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Specialty Pharmacies 98

STAT

DECEMBER 5, 2023

NEW YORK — Will the world actually soon spend $100 billion a year on the new obesity medicines? Plenty of people in pharma and at the banks that invest in it seem to think so. Goldman Sachs, Barclays, BMO Capital Markets and Pfizer have all arrived at the glossy, cut-for-headline number for spending by around 2030. Yet Jared Holz, a healthcare strategist at Mizuho, is skeptical.

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Fierce Healthcare

DECEMBER 5, 2023

CVS Health is overhauling the way it reimburses its pharmacies for prescription medications as the healthcare industry faces increased scrutiny for high drug prices. | CVS Health is overhauling the way it reimburses its pharmacies for prescription medications as the healthcare industry faces increased scrutiny on high drug prices.

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STAT

DECEMBER 5, 2023

About a decade ago, Mike Jensen, a pediatric oncologist at Seattle Children’s hospital, licensed to a startup his designs for a powerful new type of therapy, called CAR-T, that would re-engineer a child’s own immune cells to target cancer. The deal proved be a mixed blessing. The therapy eventually reached market as Breyanzi, one of three CAR-Ts approved for adult leukemia.

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Immunization Hospitals 118

Fierce Healthcare

DECEMBER 5, 2023

Nearly 60% of doctors who practice as employees of hospitals and other corporate entities say that non-physician practice ownership results in lower quality patient care, per a new survey. | Most docs surveyed cited decreased time with patients and greater focus on financial success as elements negatively affecting quality at non-physician-owned medical practices, with 70% saying their employer uses incentives or penalties to have them see more patients a day.

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Patient Care Hospitals 118

Pharmacy Times

DECEMBER 5, 2023

Trastuzumab deruxtecan and elacestrant both represent important new treatment options for subgroups of patients with breast cancer.

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FDA 130

PharmExec

DECEMBER 5, 2023

TAR-200 has a novel targeted releasing system for the treatment of patients with Bacillus Calmette-Guérin-unresponsive high-risk non-muscle-invasive bladder cancer who are ineligible for bladder removal surgery.

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FDA 116

pharmaphorum

DECEMBER 5, 2023

In a new episode of the pharmaphorum podcast, web editor Nicole Raleigh speaks with Ari Tulla, CEO and co-founder of Elo Health, about his ‘big vision’ to transform food – changing it from a leading cause of disease to the medicine it can be.

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Fierce Pharma

DECEMBER 5, 2023

Travere Therapeutics will reduce its workforce by 20%, with the jo | Travere Therapeutics will reduce its workforce by 20%, with the job cuts focused on “non-field-based employees,” the company said on Tuesday. The layoffs are part of a shake-up of the San Diego-based company as it focuses on its launch of kidney drug Filspari and develops pegtibatinase as a potential treatment for the metabolic disorder homocystinuria (HCU).

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STAT

DECEMBER 5, 2023

WASHINGTON — Members of the Senate Finance Committee took their first steps today toward using Medicare payment policy to fix drug shortages. Drug shortages are particularly vexing because they’re mostly caused by policies within the control of the government, as opposed to outside shocks such as natural disasters. Instead, it’s economic factors — the complicated way Medicare pays hospitals or the dominance of group purchasing organizations that buy hospital drugs &#x

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Hospitals 109

The Checkup by Singlecare

DECEMBER 5, 2023

People in the U.S. fill more than 6 billion prescriptions per year, so it’s only natural that we start to see a few similarities in certain states. In 2023, nine drugs made our annual list of top prescriptions by state, with vitamin D being the most filled. With two out of five Americans deficient in the nutrient, this ranking makes a lot of sense. Other medications that top the list treat conditions like high blood pressure, erectile dysfunction, or common infections.

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Mayo Clinic Department of Veterans Affairs Labelling Medical Schools 105

Drug Store News

DECEMBER 5, 2023

DSN spoke to Dr. Clive Fields, co-founder and chief medical officer at VillageMD, to discuss the challenges that lie ahead for the healthcare space.

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The Checkup by Singlecare

DECEMBER 5, 2023

Ozempic became one of the most talked about drugs in 2023. Popular media outlets like Variety and Fortune caught onto this secret to celebrity weight loss and made this medication a viral sensation. The #ozempic tag on TikTok has amassed over 1 billion views to date. Elon Musk posted his endorsement of Ozempic on X. Jimmy Kimmel joked about it in his monologue at the 2023 Oscars.

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Insurance Prescription Filling FDA Dosage 105

pharmaphorum

DECEMBER 5, 2023

The pharma industry and the UK government may have reached an accord on the voluntary scheme of rebates used to limit rises in medicines spending in the UK, but the alternative statutory scheme remains a prickly subject.

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Drug Store News

DECEMBER 5, 2023

CVS is introducing CVS CostVantage and CVS Caremark TrueCost to drive aligned incentives and deliver a more transparent and sustainable reimbursement model while launching the CVS Healthspire brand for its health services segment.

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European Pharmaceutical Review

DECEMBER 5, 2023

Results from Geron’s Phase III IMerge trial evaluating its first-in-class investigational telomerase inhibitor imetelstat, have shown long-term and durable response in participants with a rare haematologic malignancy. Efficacy of the treatment was compared to placebo in patients with lower risk myelodysplastic syndromes (MDS) relapsed/refractory or ineligible for erythropoiesis stimulating agents (ESAs).

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Hospitals FDA 103

Fierce Pharma

DECEMBER 5, 2023

As antibody-drug conjugates (ADCs) grow their importance in the oncology treatment space, efforts are underway to combine them with other agents. Enter Seagen. | Seagen unveiled detailed data showing its Tukysa could offer additional tumor progression benefit on top of Roche’s ADC Kadcyla. But with a negative early trend in overall survival, Seagen seems not ready to knock on the FDA’s door.

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FDA 101