Mon.Jun 26, 2023

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More than 60 researchers ask Congress to support innovation

PhRMA

Earlier this month, 62 researchers from our member companies came to Washington, DC to meet with congressional offices during our annual fly-in event. This year included a record-breaking number of meetings — 145 over the course of the day.

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Opioid Use Disorder Treatment Inconsistent Around United States

Drug Topics

At the state level, medication treatment rates ranged from 17.7% in Kansas to 82.8% in Maine.

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Trending Sources

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STAT+: Illumina to lay off 10% of research and development team in bid to cut costs by $100 million

STAT

SAN DIEGO — Months after announcing plans to cut costs by $100 million, DNA sequencing giant Illumina has begun to lay off 10% of its research and development team, according to internal emails obtained and reviewed by STAT. The layoffs, which began last Wednesday, impact research teams across the company’s California sites in San Diego and Foster City, as well as locations in Madison, Wisconsin; Singapore; and the United Kingdom.

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FDA Approves Pfizer’s Ritlecitinib for Treatment of Alopecia Areata in Adolescents

Pharmacy Times

This approval makes ritlecitinib, in the 50 mg dosage, the first and only treatment approved by the FDA for adolescents aged 12 years and older with severe alopecia areata.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: STAT-Harris Poll: Nearly half of U.S. adults would spend $100 a month for Ozempic, other weight-loss drugs

STAT

Almost half of Americans would be willing to spend up to $100 a month for new weight-loss medicines such as Wegovy, and one-third say they would indefinitely pay whatever they can afford to get the drugs, according to a new survey by STAT and The Harris Poll. Although 47% say they would only spend the money up to a point — such as losing a certain amount of weight, or up until a special event — demand is so great that nearly one-quarter said they would pay up to $250 each month.

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Final Data From SURMOUNT-2 Show Superior Weight Loss With Tizepatide for Diabetes

Pharmacy Times

The results of the study were presented at the 83rd Scientific Sessions of the American Diabetes Association in San Diego, California and were also published in The Lancet.

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More Trending

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Expert: Advocacy, Support for LGBTQ+ Pharmacy Colleagues Is Crucial to Improving Representation

Pharmacy Times

Liam Volk, MPharm, discussed the recent end of the FDA’s ban on gay and bisexual men donating blood, saying it’s a good step, although more must be done.

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UnitedHealth outbids Option Care Health for Amedisys in $3.3B deal

Fierce Healthcare

UnitedHealth Group has once again flexed its muscles and outbid a competitor to pick up another home health asset. | Amedisys on Monday agreed to be acquired by UnitedHealth's Optum unit in an all-cash deal while also scraping a previous all-stock deal offer from previous suitor Option Care Health.

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Employees Frequently Using AI Systems Are More Likely to Experience Loneliness, Insomnia

Pharmacy Times

Employees who did frequently use AI systems were more than likely to offer help to fellow employees, though it could have been a response to their loneliness.

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RPhCast, Episode Three: Avoiding Burnout And Still Achieving Your Goals

Drug Topics

Shawn and Tammy from RPhAlly talk about burnout, trying to "overachieve", and how to avoid overworking yourself and your brain in this industry.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Employers seek guidance on mental health benefits: survey

Fierce Healthcare

Employers give themselves poor marks in terms of providing mental health services to their employees but high scores for supporting initiatives to improve diversity, equity and inclusion among thei | Employers recognize the importance of mental health benefits but feel that they might be falling short in providing them, according to a new survey.

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Lundbeck replaces retiring CEO Dunsire with UCB exec after breaking sales record

Fierce Pharma

Lundbeck CEO Deborah Dunsire is stepping down on a high note in the neuroscience company’s history. | Lundbeck CEO Deborah Dunsire is retiring on a high note in the neuroscience company’s history. After hitting the company's highest quarterly revenue in the first quarter, the five-year Lundbeck chief executive will pass the baton to UCB's neurology head.

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Pharmacy Focus: Oncology Edition - A Look Into Psychedelic Medicines for Oncology Care

Pharmacy Times

This month, we have a special crossover episode between Pharmacy Focus: Oncology Edition and the Psychedelic Pharmacy podcast.

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‘I felt like I was dying’: How women with postpartum depression fall through the cracks of U.S. health care

STAT

Five and a half months after Kristina Dulaney had her second daughter, she developed postpartum psychosis. One day, she spontaneously quit her job as a nurse — which she doesn’t remember doing. Soon after, she began to quote scripture, grabbed her kids, and begged God to save them all. Then she passed out, and her husband called 911. Dulaney spent two nights in a behavioral health emergency room before being sent to a general inpatient unit that had both men and women in Greensboro

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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ADA: Novo Nordisk, Eli Lilly show progress for oral GLP-1 treatments for obesity

Fierce Pharma

The potential advantages of a daily-pill version of popular GLP-1 drugs for Type 2 diabetes and obesity are obvious compared to the weekly-injection routine most patients taking these drugs undergo | The potential advantages of a daily-pill version of popular GLP-1 drugs for Type 2 diabetes and obesity are obvious compared to the weekly-injection routine most patients taking these drugs undergo.

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2024 DIR Changes May Bring Financial Challenges to Independent Pharmacies

Pharmacy Times

Pharmacies should start to prepare for cash flow challenges when the direct and indirect remuneration changes in 2024.

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Over Half of At-Home Ketamine Users Misuse the Treatment

Drug Topics

A new report recommended that ketamine therapy be used only in combination with psychotherapy under the supervision of a clinician.

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NASH drugs race to cross the finish line

Pharmaceutical Technology

After Intercept’s Ocaliva rejection, multiple companies are taking aim at becoming the first US-approved NASH therapy.

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Six-Month Survival Following Heart Transplant After Donor Circulatory Death Is Noninferior to Transplant After Donor Brain Death

Pharmacy Times

Notably, donor hearts from those who underwent circulatory death were able to be preserved and analyzed in situ.

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STAT+: Fatty liver disease was alleviated by Lilly’s ‘triple-G’ obesity drug in small study

STAT

SAN DIEGO — An experimental obesity drug from Eli Lilly significantly reduced liver fat in a small analysis, supporting further studies of the treatment against nonalcoholic fatty liver disease, an increasingly common condition that lacks approved treatments. Among 98 patients with nonalcoholic fatty liver disease, those on the highest dose tested of the drug, retatrutide, experienced an 86% decrease in liver fat over 48 weeks, with most of the reduction occurring early on in treatment, a

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In approving Sarepta's DMD gene therapy, FDA's Peter Marks overruled reviewers' rejection

Fierce Pharma

The FDA's review teams were moving against an approval of Sarepta's Duchenne muscular dystrophy gene therapy. | The FDA's review teams were moving against an approval of Sarepta's Duchenne muscular dystrophy gene therapy. But Peter Marks, director of the agency's Center for Biologics Evaluation and Research, disagreed with the staffers' interpretations, coming to a "different conclusion" that led to an eventual approval, a memo shows.

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Watch DSN: ASHP’s Ganio highlights ongoing medication shortages

Drug Store News

Michael Ganio, senior director of pharmacy practice and quality at The American Society of Health-System Pharmacists, highlights current shortages of medications in certain therapeutic categories.

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Pfizer's Litfulo enters the scene in alopecia with adolescent nod to rival Lilly's Olumiant

Fierce Pharma

On the heels of Eli Lilly’s landmark approval last summer, Pfizer is stepping up to the plate in alopecia areata—and it’s coming equipped with an adolescent nod to put the pressure on Olumiant. | Late last week, the FDA gave a green light to Pfizer’s once daily oral JAK inhibitor ritlecitinib—now christened Litfulo—in adults and children ages 12 and over with severe alopecia areata.

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Opinion: Health misinformation is rampant in youth baseball. Why isn’t MLB doing more to help?

STAT

“W e all know that we are in the middle of an epidemic with our youth throwers,” an orthopedic specialist opined in a March editorial. The sports medicine professionals and readers of the journal Arthroscopy may know this, but it is far from common knowledge among parents and coaches in youth baseball leagues. As scientists and sports fans, we are particularly interested in a scientific, evidence-based approach to injury prevention and sports medicine.

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FDA Approves Ritlecitinib for Alopecia Areata for Adolescents, Adults

Drug Topics

The once-daily oral medication is the first and only treatment approved by the agency for adolescents with the disease.

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Understanding Generational Differences Can Help Independent Pharmacies Retain Top Talent

Pharmacy Times

Common assumptions about each generation are often incorrect, according to an expert in generational research.

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Watch DSN: ASHSP’s Ganio highlights ongoing medication shortages

Drug Store News

Michael Ganio, senior director of pharmacy practice and quality at The American Society of Health-System Pharmacists, highlights current shortages of medications in certain therapeutic categories.

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STAT+: Pharmalittle: Nearly half of U.S. adults would spend $100 a month for weight loss drugs; Pfizer scraps an obesity pill

STAT

Good morning, everyone. and welcome to another working week. We hope the weekend respite was restful and invigorating because now that familiar routine of online meetings, deadlines, and what-not has predictably returned. But what can you do when the world, such as it is, keeps spinning? As you might expect, we are coping by quaffing a few cups of welcome stimulation — our flavor today is Southern Pecan — and, as always, we invite you to join us.

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Regulators and Industry Discuss Digital Transformation and Pharma 4.0™

ISPE

Regulators and Industry Discuss Digital Transformation and Pharma 4.0™ Trudy Patterson Mon, 06/26/2023 - 10:37 iSpeak Blog iSpeak Regulators and Industry Discuss Digital Transformation and Pharma 4.0™ Thomas ZIMMER, PhD 26 June 2023 The upcoming challenges and opportunities of digital transformation were the topic of a panel discussion held on 9 May 2023 at the 2023 ISPE Europe Annual Conference in Amsterdam, The Netherlands.

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Low-dose aspirin increases anaemia risk among elderly patients

Hospital Pharmacy Europe

The risk of anaemia is higher among patients aged 70 years and older taking a daily dose of 100 mg of enteric-coated aspirin, according to a post hoc analysis of the ASPREE randomised controlled trial. The Aspirin in Reducing Events in the Elderly (ASPREE) trial was designed to examine whether a daily dose of 100 mg of aspirin would prolong the healthy life span of older adults.

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STAT+: Shareholders elect director’s romantic partner to Biogen’s board

STAT

Biogen shareholders voted to add biotech executive Susan Langer, who is the romantic partner of departing director Alex Denner, to its board of directors on Monday, concluding a weeklong episode that led some investors to question the company’s leadership. Langer, 32, will join the eight-member board for a one-year term. Denner, who nominated her, did not stand for reelection.

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Biogen shareholders vote in Susan Langer as director despite relationship with former board member

Fierce Pharma

Despite the controversy surrounding a relationship with departing director Alex Denner, Susan Langer has secured enough investor support to join Biogen’s board. | Despite the controversy surrounding a relationship with departing director Alex Denner, Susan Langer has secured enough investor support to join Biogen’s board.

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RK Pharma completes acquisition of VGYAAN Pharmaceuticals

Drug Store News

RK Pharma said the acquisition will give the company an exciting product portfolio, meaningful partnerships and a proven team with an impressive track record.

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After early win in type 1 diabetes, Vertex joins forces with Lonza on new cell therapy production plant where it plans to employ 300

Fierce Pharma

After early win in type 1 diabetes, Vertex joins forces with Lonza on new cell therapy production plant where it plans to employ 300 fkansteiner Mon, 06/26/2023 - 10:05

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