Tue.Jun 18, 2024

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Value-Based Care Models Can Help Pharmacies Improve Operations

Drug Topics

Sandra C. Canally, RN, founder and CEO of The Compliance Team, discussed the goals, benefits, and opportunities of value-based care in pharmacy.

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Opinion: Long Covid feels like a gun to my head

STAT

I have spent my career studying infectious diseases that fall under the heading of neglected tropical diseases. Now I have a neglected disease — long Covid — an incurable (for now and for me) disease. As a medical anthropologist working in global health, I thought I understood the despair of poor health. I didn’t. I join 7% of the U.S. adult population — or about 18 million Americans — who have experienced long Covid.

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Meeting Preview: McKesson ideaShare 2024

Drug Topics

From the Health Mart Pharmacy of the Year award presentation to general sessions covering pharmacy profitability, community impact, and much more, see what’s to come at this year’s meeting in New Orleans.

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Opinion: With the threat of H5N1 bird flu, hospitals must stay prepared

STAT

A third case of mammal-to-human transmission of the highly pathogenic H5N1 bird flu virus has been reported in the United States. This latest case, involving a dairy worker in Michigan , raises concerns due to the individual exhibiting respiratory symptoms, highlighting the pandemic potential of this virus. U.S. hospitals need to prepare for the worst and hope for the best.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Study Finds Asthma Severity is Not Associated With Reactivity to Allergen Skin Testing

Pharmacy Times

The findings also show that skin testing positivity for perennial allergens was higher in patients with childhood-onset asthma compared with those with adult-onset asthma.

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Another heat wave is hitting the U.S. Here’s what you need to know

STAT

Extreme heat is coming this week in many parts of the United States. The Midwest and Northeast in particular will see weather that puts them in the National Weather Service’s highest heat risk category — when lack of cooling or hydration can put almost anyone in harm’s way. It’s a new labeling system for the NWS, which launched the experimental rating at the end of April with the Centers for Disease Control and Prevention in response to the growing danger of extreme h

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STAT+: How a tweet about a gene discovered long ago led to a $190 million startup and, maybe, hope for heart disease

STAT

A 10-person startup called Marea said Tuesday that it had raised $190 million to help develop a drug to lower a type of cholesterol — what scientists call “remnant cholesterol” — that could represent a new way of attacking cardiovascular disease. The story of that drug, the protein that it targets, and the gene that codes for that protein (both are called ANGPTL4) says a lot about why medicines are so tough to develop and why heart disease remains the bigges

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FDA Approves Pembrolizumab With Chemotherapy to Treat Adult Patients With Endometrial Carcinoma

Pharmacy Times

The indication is for adult patients with primary advanced or recurrent endometrial carcinoma and is the third indication that pembrolizumab has received for this disease state.

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On the road to eliminate rabies, Gavi announces plan to improve human vaccination

STAT

Rabies has been in global health’s crosshairs for years. Around the world, the viral infection kills about 70,000 people a year — and since as early as 2015, groups including Gavi, the Vaccine Alliance, have had plans to shore up vaccine efforts to reduce the number. At one point, Gavi planned to include human rabies vaccines in its 2021 investment strategy — but then the Covid-19 pandemic got in the way.

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Kansas AG accuses Pfizer of misrepresenting COVID vaccine, hiding safety risks in lawsuit

Fierce Pharma

Kansas Attorney General is accusing Pfizer of "misrepresenting" its vaccine's safety and efficacy in a 179-page civil suit.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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To treat obesity in children, task force favors behavioral therapy over drugs like Wegovy

STAT

A national advisory organization has come down on the side of behavioral interventions, not obesity medications, to help children 6 and older with high BMI improve their health, wading into the debate over prescribing the blockbusters for kids before their long-term consequences are better understood. On Tuesday, the United States Preventive Services Task Force issued recommendations encouraging clinicians to provide or refer children and adolescents 6 years or older with a high body mass index

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Q&A: How Will the FDA Panel's Decision on MDMA Impact the Future of Psychedelic Medicine?

Drug Topics

Sam Clark, MD, PhD, founder and CEO of Terran Biosciences, discusses what the future looks like for psychedelic treatments.

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STAT+: To feed an AI that designs new enzymes, Basecamp hunts rare proteins at the world’s end

STAT

Not many AI companies have expeditions to the rainforest on the calendar, or need scientists who’ve lived in Antarctica on the payroll. “One of them was the diving instructor for Jason Momoa,” said Philipp Lorenz, chief technology officer at Basecamp Research. “She’s one of our field scientists.” Basecamp, headquartered in London, positions itself as the “bridge between biodiversity and biotech.

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AHIP 2024: Not just a buzzword—payers envision AI’s future

Fierce Healthcare

You can’t spell AHIP without AI. | Health insurance executives are captivated by artificial intelligences' use cases. Here's where they see advancements on the horizon.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Diabetes and the Skin: Complications and Prevention Tips

Drug Topics

Skin complications are common in patients with diabetes, but pharmacists can recommend several easy measures to help.

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Novant Health gives up $320M hospital deal after FTC secures appeals court injunction

Fierce Healthcare

Novant Health is throwing in the towel on its $320 million plan to purchase two Community Health Systems hospitals after the Federal Trade Commission (FTC) scored an injunction on the deal from an | "With the FTC’s continued roadblocks we do not see a way to finalize this transaction," a spokesperson for the nonprofit system said Tuesday.

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AstraZeneca's Truqap misses the mark in late-stage triple-negative breast cancer trial

Fierce Pharma

While AstraZeneca’s Truqap bears the distinction of being the first AKT inhibitor to pass muster with the U.S. | In the late-stage CAPItello-290 study, Truqap plus the chemotherapy paclitaxel failed to help extend the lives of patients with locally advanced or metastatic triple-negative breast cancer (TNBC) over paclitaxel and placebo alone, AstraZeneca said Tuesday.

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FDA Approves Pneumococcal 21-Valent Conjugate Vaccine Capvaxive

Drug Topics

The vaccine covers 8 serotypes not currently covered by any FDA-approved pneumococcal vaccines.

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Avoiding the pharma ‘junk pile’ with launch readiness, pipeline rigor and ‘quick kills’

PharmaVoice

Drug launches have underperformed expectations at a high rate, and pharmas need to get better at thinning the pipeline to make room for the real wins, says a life sciences consultant.

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The 2024 Smarter Purchasing Report

Drug Topics

SureCost's annual Smarter Purchasing Report offers a comprehensive, anonymized analysis of customer data to monitor trends and create a vital resource for pharmacies navigating an increasingly complex industry. This user-friendly report, based on insights from hundreds of pharmacies, provides a holistic view of emerging trends and persistent challenges.

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12 Questions with Caroline Phillips

pharmaphorum

Dive into an exclusive Medscape interview with HCP Caroline Phillips as she shares her insights, experiences, and advice. Discover the key takeaways that can benefit your medical practice.

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Intra-Cellular's Caplyta scores again in major depressive disorder as blockbuster expansion comes within reach

Fierce Pharma

Intra-Cellular Therapies’ surging antipsychotic Caplyta has scored again with remarkable trial results, fueling its bid for a third and potentially most lucrative indication—major depressive disord | Intra-Cellular Therapies’ surging antipsychotic Caplyta has scored again with remarkable trial results, fueling its bid for its third and potentially most lucrative indication—major depressive disorder.

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Neuroplastogens: A novel approach to treat neurological diseases

pharmaphorum

Learn about the innovative approach of using neuroplastogens, including psychedelics, to treat neurological diseases. Explore the potential benefits and risks of this novel treatment method.

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Methadone Dispensing at Discharge Can Help Shorten Hospital Stays for Patients with OUD

Drug Topics

A posted presented at ASHP 2024 examined if improved access to methadone could decrease hospital length of stay and readmission rates.

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FDA Approves V116 for Prevention of Invasive Pneumococcal Disease and Pneumonia

Pharmacy Times

V116 (Capvaxive; Merck) elicited higher immune responses than the comparator for the serotypes that are unique to the vaccine, according to studies submitted to the FDA.

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NIH awards Cellibre $2M to advance sustainable cannabinoid ingredient production

Outsourcing Pharma

Cellibre, a pioneer in sustainable biochemical manufacturing, has received a $2 million grant from the National Center for Complementary and Integrative Health (NCCIH) at the National Institutes of Health (NIH).

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CDC: Uninsured rate fell by 26% between 2019 and 2023

Fierce Healthcare

The uninsured rate in the U.S. has declined by 26% over the past several years, according to new data from the Centers for Disease Control and Prevention. | The uninsured rate in the U.S. has declined by 26% over the past several years, according to new data from the Centers for Disease Control and Prevention.

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FDA says yes to MSD’s 21-valent adult pneumococcal jab

pharmaphorum

The rivalry between Pfizer and MSD in pneumococcal vaccines has dialled up a notch with the FDA approval of MSD’s new shot Capvaxive, the first to be aimed specifically at adults.The 21-valent product – formerly known as V116 – covers a wider range of Streptococcus pneumoniae serotypes than any of MSD’s earlier vaccines and eight that are not covered by any other approved pneumococcal vaccine.

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Slideshow: Exploring Dementia Risk, Hot Flashes, Oral Health in Postmenopausal Women

Drug Topics

Four posters presented at ENDO 2024 explored the interplay of hormones and other factors in postmenopausal women.

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STAT+: Boston Scientific to buy vascular device maker for $1.16 billion

STAT

Boston Scientific said on Tuesday it will buy Silk Road Medical, a medical device company treating stroke, for $1.16 billion.  Silk Road Medical sells technology meant to prevent stroke in patients with carotid artery disease, a condition creating blockages in the major blood vessels connected to the brain. The company’s core products enable a procedure that temporarily sends blood flow away from the brain to prevent plaque from blocking the vessel.

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7 health benefits of green beans

The Checkup by Singlecare

Green beans are a staple of American diets—as a daily side dish or in a Thanksgiving casserole. These nutritious legumes (part of the genus Phaseolus vulgaris ) have a savory, earthy taste along with a tender-crisp texture. They go by many other names, such as the common bean, string beans, snap beans, and French beans. Whatever you call them, green beans contain a ton of beneficial nutrients, such as dietary fiber and antioxidants.

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FDA clears Roche digital pathology platform for diagnosis

pharmaphorum

Roche’s move into the digital pathology category has been boosted by FDA approval of a lab instrument and toolkit for use as an aid to clinical diagnosis.The clearance covers Roche’s Ventana DP 200 slide scanner, digital pathology workflow software, and a display that can be used to review and interpret digital images of scanned pathology slides.

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How long does Trintellix withdrawal last?

The Checkup by Singlecare

Trintellix (vortioxetine) is a brand-name prescription medication that’s approved by the Food and Drug Administration (FDA) to treat major depressive disorder (MDD) in adults. Some healthcare providers also prescribe it off-label for anxiety. Although it’s classified as an atypical antidepressant, Trintellix works similarly to selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine or paroxetine.

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STAT+: Freespira bets on slow and steady, amid spectacular digital health collapses

STAT

Many digital health companies have crashed and burned after promising investors speedy adoption and huge revenues. Freespira, maker of a software- and device-based treatment for panic and post-traumatic stress disorders, has taken a different strategy: Slowly build to profitability a few thousand patients at a time. Freespira CEO Joe Perekupka told STAT the company believes it will break even by the end of 2025 and will become cash flow positive in 2026.

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