Fri.Nov 24, 2023

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Flu Vaccine May Protect Against Heart Attack, Cardiovascular Events

Drug Topics

Study authors recommend that healthcare personnel consider prioritizing influenza vaccination for patients with recent cardiovascular diseases (CVDs) in light of new evidence.

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Holiday Gift Ideas for Pharmacists and Pharmacy Technicians

Pharmacy Times

For pharmacists and pharmacy technicians, who work diligently to ensure our health and well-being, choosing the perfect holiday gift can be a thoughtful way to express gratitude and brighten their season.

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Prepregnant Energy Drink Consumption Increases Gestational Hypertension Risk

Drug Topics

Reproductive-aged women who consume energy drinks should be aware of the potential risks, as energy drink consumption has been linked to adverse pregnancy outcomes.

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Pandemic-related immunity gap in kids explains surge of respiratory infections in children in China, says WHO

STAT

Reports this week that China is experiencing a surge in respiratory infections in young children triggered flashbacks of the start of the Covid-19 pandemic among infectious disease watchers. But a rapidly organized meeting Thursday between the World Health Organization and health officials in China assuaged much of that concern. The evidence presented to the WHO team pointed to what’s sometimes called an immunity gap that was created by the pandemic.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Addressing Burnout: When the Body Says ‘Enough’

Pharmacy Times

In part 2 of this series, trauma-informed pharmacist Helen Sairany, PharmD, MBA, discusses the physical manifestations of burnout.

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STAT+: Antitrust lawsuit alleges UnitedHealth’s Optum pressured a California hospital to stop competing over physicians

STAT

UnitedHealth Group’s Optum division is already the largest employer of physicians in the United States, but allegations in a new lawsuit suggest Optum is hungry for more. Emanate Health, a nonprofit group of hospitals and physicians in California, filed a federal lawsuit Monday, alleging Optum pushed it to agree not to compete for primary care physicians, a violation of antitrust law.

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Opinion: Hospices can’t handle the growing number of patients who need wound care

STAT

A few years ago, I worked with a patient close to 100 years old. She had diabetes for most of her adult life, which affected circulation in her foot. Without circulation to her foot, it turned black, and then her calf turned black. In this stage of deterioration, no one is talking about treating metabolic disease; often, patients even stop checking their blood sugar.

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New Amgen immunotherapy could treat common solid tumour

European Pharmaceutical Review

Amgen’s new immunotherapeutic agent Tarlatamab has been shown in a Phase II trial to provide sustained anti-tumour activity in 40 percent of the small cell lung cancer patients. The international DeLLphi-301study was investigated as a new anti-cancer treatment option for patients previously considered to be beyond treatment. Results from the trial were published in the New England Journal of Medicine.

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Opinion: I grew up in one of Africa’s largest informal settlements. Now I’m helping heal it

STAT

I had only lived in Kibera for 15 minutes when I saw a police officer and was arrested. But it would be years before I saw a real doctor. In 2001, at the age of 13, I had come to Kenya’s largest informal settlement on the outskirts of Nairobi with my sister. When we arrived at 3 a.m., we dutifully called my uncle from a phone booth to pick us up.

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Alladapt Immunotherapeutics gains FDA Fast Track Designation for ADP101 as food allergy treatment

Pharmafile

Alladapt Immunotherapeutics has announced that ADP101 has received Fast Track Designation from the US Food and Drug Administration (FDA) as a treatment for one or more food allergens. ADP101 is currently the most advanced multi-food oral immunotherapy (mOIT) candidate in development, and there are currently no FDA-approved OIT treatments for multi-food allergy to foods other […] The post Alladapt Immunotherapeutics gains FDA Fast Track Designation for ADP101 as food allergy treatment appea

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Novo Nordisk to expand French production facilities

European Pharmaceutical Review

Novo Nordisk is investing over €2.1 billion (16 billion Danish kroner) to expand its production site in Chartres, France, supporting manufacture of its products for serious chronic diseases. Novo Nordisk’s multi-billion facility expansion This financial commitment will greatly strengthen manufacturing capacity, more than doubling the site’s footprint.

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Bayer expands German manufacturing facilities to fulfill supply demand

Pharmaceutical Technology

Bayer announced the launch of a Berlin, Germany-based manufacturing facility to meet future demands from the US, China and Europe.

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Vertex scores European cystic fibrosis medicine approval

European Pharmaceutical Review

The European Commission has granted a label expansion of the combination treatment KAFTRIO ® (ivacaftor/tezacaftor/elexacaftor) with ivacaftor, for children aged two to five years old with cystic fibrosis. The treatment from Vertex Pharmaceuticals is indicated for individuals who have at least one F508del mutation in the cystic fibrosis transmembrane conductance regulator ( CYSTIC FIBROSISTR ) gene.

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International Health Partners' Christmas campaign: Working with pharma for patients worldwide

pharmaphorum

International Health Partners' Christmas campaign: Working with pharma for patients worldwide Nicole.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Calliditas Therapeutics' partner Everest Medicines' announces kidney drug approval

Outsourcing Pharma

Calliditas Therapeutics AB announced today (November 24) that its partner Everest Medicines has revealed that China's National Medical Products Administration (NMPA) has approved Nefecon.

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How to optimise commercial-scale ATMP manufacturing through automation

pharmaphorum

How to optimise commercial-scale ATMP manufacturing through automation Mike.

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Progress for Johnson & Johnson's lung cancer drug as extension submitted to EMA

Outsourcing Pharma

The Janssen Pharmaceutical Companies of Johnson & Johnson announced last week (November 23) the submission of a type 2 extension of indication application to the European Medicines Agency (EMA).

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Syncona to acquire Freeline Therapeutics for $28.3m

Pharmafile

Freeline Therapeutics has announced that it has entered into a definitive agreement with newly established portfolio company Syncona, in which Syncona will acquire Freeline in an all-cash transaction. Syncona will pay $6.50 per share, or an approximate total of $28.3m. The acquisition is expected to close in the first quarter of 2024, although it is […] The post Syncona to acquire Freeline Therapeutics for $28.3m appeared first on Pharmafile.

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Progress for Johnson & Johnson's lung cancer drug as extension submitted to EMA

Outsourcing Pharma

The Janssen Pharmaceutical Companies of Johnson & Johnson announced last week (November 23) the submission of a type 2 extension of indication application to the European Medicines Agency (EMA).

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Vertex obtains EC approval for combination therapy to treat CF

Pharmaceutical Technology

Vertex Pharmaceuticals has obtained approval from EC) for the label expansion of Kaftrio plus ivacaftor to treat children with CF.

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NHS Confederation, ABPI say break down barriers to partnerships and change the lives of millions

pharmaphorum

NHS Confederation, ABPI say break down barriers to partnerships and change the lives of millions Nicole.

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Sosei to regain rights to IBD drug after GSK discontinues programme

Pharmaceutical Technology

The Sosei Heptares oral IBD drug was first licensed to GSK in 2020 and is currently in Phase I clinical development.

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DSCSA Compliance for Independent Pharmacies

DiversifyRx

While DSCSA (the Drug Supply Chain Security Act) enforcement is postponed until November 2024, it is critical to move forward in becoming compliant sooner rather than later. In the world of running a pharmacy, patient safety is Everything. To achieve this, the U.S. pharmaceutical industry is wrapped up in a web of regulations, and one of the most significant in recent years is the Drug Supply Chain Security Act (DSCSA).

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Johnson & Johnson sees highest patent filings and grants during August in Q3 2023

Pharmaceutical Technology

Access and buy GlobalData’s databook on the latest filings and grants activity for Johnson & Johnson here.

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Why We Were Not Properly Winterized for RSV Season

BioPharm

Looking at the role that RSV and pediatric medical practices play in drug shortages.

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F. Hoffmann-La Roche sees highest patent filings and grants during August in Q3 2023

Pharmaceutical Technology

Access and buy GlobalData’s databook on the latest filings and grants activity for F. Hoffmann-La Roche here.

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Lithuania Set to Become Home to Largest Biotech City

BioPharm

The largest biotech hub is set to be built in Lithuania by Northway Group.

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Bristol-Myers Squibb sees highest patent filings and grants during August in Q3 2023

Pharmaceutical Technology

Access and buy GlobalData’s databook on the latest filings and grants activity for Bristol-Myers Squibb here.

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Intellectual property: Striking the balance

pharmaphorum

Intellectual property: Striking the balance Mike.

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What’s in a name: Agencies struggle to keep up with expanding drug space 

Pharmaceutical Technology

With more approved drugs coming through than ever before, the need to avoid confusing names to ensure patient safety is important.

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NHS urges individuals to take up cervical screening invitations

Pharma Times

Around 3,200 new cases of cervical cancer are diagnosed in the UK every year - News - PharmaTimes

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Novo Nordisk expands site to manufacture GLP-1 drugs

Pharmaceutical Technology

The expansion comes as Novo is trying to maintain strong growth in T2D after the launch of Eli Lilly’s Zepbound this month.

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Study suggests cognitive decline could be linked to hippocampus shrinkage

Pharma Times

The findings could benefit patients living with neurodegenerative conditions - News - PharmaTimes

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Novartis sees highest patent filings and grants during August in Q3 2023

Pharmaceutical Technology

Access and buy GlobalData’s databook on the latest filings and grants activity for Novartis here.

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