Fri.Apr 07, 2023

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ICYMI: PhRMA President and CEO Stephen J. Ubl discusses patient affordability

PhRMA

PhRMA president and CEO Stephen J. Ubl spoke recently at The Hill’ s event, “ Pathways to Patient Affordability.” He spotlighted patients’ affordability challenges, the unintended consequences we’re already seeing from the government price setting provisions in the Inflation Reduction Act (IRA) and how policymakers can address harmful pharmacy benefit manager (PBM) practices.

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Examining the Link Between Infections and Cognitive Decline in Older Adults

Drug Topics

Both acute and chronic infection can increase the risk of cognitive decline and dementia in older adults.

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Federal judge suspends FDA approval of abortion pill

STAT

In a case that could reshape pregnancy in America, a federal judge on Friday sided with anti-abortion groups seeking a nationwide ban on abortion pills, ruling that the Food and Drug Administration acted improperly in approving mifepristone in 2000. The ruling will go into effect in seven days if a stay is not granted by an appeals court or by the Supreme Court.

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Dupilumab Safety Evaluated in Patients With Erythrodermic AD

Drug Topics

Dupilumab monotherapy plus concomitant topical corticosteroids can improve signs, symptoms, and patient health-related quality of life.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Opinion: I declined to share my medical data with advertisers at my doctor’s office. One company claimed otherwise

STAT

I care deeply about privacy, and as a professional researcher, I take meticulous notes. During my recent maternity leave, I spent most of my hands-free time trying to figure out why my doctors were trying to give my medical data away to advertisers — even after I opted out.

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Updates on 503A Compounding: Legal and Regulatory Developments

Pharmacy Times

Part 1 of this 2-part series examines USP and revisions for sterile and nonsterile compounding, veterinary compounding, FDA inspections of 503A pharmacies, and the interstate distribution of compounded prescriptions post Wellness Pharmacy v. FDA.

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Eye Drops: Treatment Options and Infection Risks

Pharmacy Times

Eye drops come in many forms and for many indications, such as redness, itchiness, dryness, allergies, dilating drops, glaucoma drops, lubricants, numbing agents, antibiotics, and to lower pressure.

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STAT+: Liver disease researchers are hoping AI can improve their trial design

STAT

Liver disease researchers, stumped by a complex disease, are looking for new investigative tools. Artificial intelligence might be one of them.  At a small conference of the American Association for the Study of Liver Diseases in Los Angeles last month, experts gathered to compare notes on nonalcoholic steatohepatitis, a form of nonalcoholic fatty liver disease commonly known as NASH.

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Eli Lilly Invests Heavily in Debut Mounjaro TV Ad Campaign for Diabetes

PharmExec

Eli Lilly debuts its first Mounjaro TV commercial amid high demand for the diabetes injection, which also shows promise in weight loss applications and outperformed rivals Ozempic and Wegovy in clinical trials.

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Wellness Support Group Shows Promise in Reducing Burnout

Pharmacy Times

Discussions are led by a variety of experienced preceptors to provide insight, strategies, and resources for pharmacy residents.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Enanta secures FDA fast track designation for EDP-323 to treat RSV

Pharmaceutical Technology

Enanta Pharmaceuticals has secured the US Food and Drug Administration’s (FDA) fast track designation for EDP-323 to treat respiratory syncytial virus (RSV). In vitro data of EDP-323 showed a significant reduction in RSV replication with picomolar potency in primary human bronchial epithelial cells against RSV A and B. Consistent potency was also observed across a range of RSV clinical isolates in several cell types.

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STAT+: A new AI tool aims to help surgeons quickly analyze brain tumor mutations during surgery

STAT

When it comes to treating brain tumors, sometimes less is more in the operating room. If it’s a lymphoma, a doctor might want to just get enough tissue to confirm the diagnosis and get out. If it’s an astrocytoma, a surgeon will want to cut out every possible piece of the tumor. The same goes for oligodendroglioma, though for these tumors, getting out the last of a tumor may not be worth damaging the patient’s ability to walk or speak.

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Cancer and heart disease vaccines ‘ready by end of the decade’

The Guardian - Pharmaceutical Industry

Exclusive: Pharmaceutical firm says groundbreaking jabs could save millions of lives ‘A silver lining’: how Covid ushered in a vaccines golden era Millions of lives could be saved by a groundbreaking set of new vaccines for a range of conditions including cancer, experts have said. A leading pharmaceutical firm said it is confident that jabs for cancer, cardiovascular and autoimmune diseases, and other conditions will be ready by 2030.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.   That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Watch DSN: CVS Health works to make clinical research more accessible

Drug Store News

DSN interviewed Omar Abdelsamad, executive director of patient recruitment, clinical trial services at CVS Health, about the company’s entry into a new therapeutic space—chronic kidney disease.

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Digital pathology experts say that human-centered augmented intelligence will remain the standard for pathology, radiology

Fierce Healthcare

Digital pathology experts say that human-centered augmented intelligence will remain the standard for pathology, radiology aburky Fri, 04/07/2023 - 16:13

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Costco’s March sales driven by consumers seeking essential items

Drug Store News

In line with perceptions that consumers are less prone to buying bigger-ticket items in today’s economy, Costco’s March sales report showed resilience in food and downturns in nonfoods.

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FDA withdraws approval of preterm birth drug Makena

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has rescinded its approval for Swiss drug maker Covis Pharma’s (Covis) Makena drug and its generic versions , the only approved treatments aimed at reducing the risk of premature birth. The decision was made after studies did not prove the effectiveness of the drug in preventing preterm birth. Makena was approved by the FDA under the accelerated approval pathway in 2011 to reduce the risk of preterm birth in women with a singleton pregnancy who hav

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Can you take Zyrtec and Benadryl at the same time?

The Checkup by Singlecare

Over-the-counter medications may provide an illusion of safety since they are available without a prescription. However, taking more than one OTC treatment at a time can have very serious consequences. Benadryl (diphenhydramine) and Zyrtec (cetririzine) are the brand names of common oral antihistamines. Here is what providers say about mixing these two over-the-counter allergy medications.

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FDA withdraws approval of preterm birth drug Makena

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has rescinded its approval for Swiss drug maker Covis Pharma’s (Covis) Makena drug and its generic versions , the only approved treatments aimed at reducing the risk of premature birth. The decision was made after studies did not prove the effectiveness of the drug in preventing preterm birth. Makena was approved by the FDA under the accelerated approval pathway in 2011 to reduce the risk of preterm birth in women with a singleton pregnancy who hav

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Sweeping new study analyzes maternal health outcomes with SDOH, finds Black mothers at much higher risk

Fierce Healthcare

Sweeping new study analyzes maternal health outcomes with SDOH, finds Black mothers at much higher risk agliadkovskaya Fri, 04/07/2023 - 15:50

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STAT+: Pharmalittle: Genentech finds no evidence of fraud in paper by former top exec; FDA withdraws approval for premature-birth drug

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is, once gain, rather modest. We plan to promenade with the official mascot and his stay-over playmate, catch up on our reading, and hold another listening party with Mrs. Pharmalot — the rotation will include this , this and this.

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Pneumonia Drug Recalled Due to Potential Bacillus cereus Contamination

Drug Topics

The drug, called Atovaquone, has been voluntarily recalled due to possible Bacillus cereus contamination.

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A Brand Game-Changer? TikTok and Pharma Marketing

PharmExec

It’s time for pharma brands to recognize the potential of TikTok as a promotional platform and develop a strategy to not only stand out but make an impact.

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Wella Professionals revitalizes damaged hair with Ultimate Repair collection

Drug Store News

The collection features an intensive repair solution that rebuilds broken bonds inside the hair while replenishing the outside barrier, the company said.

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Industry Voices—As healthcare's labor shortages worsen, masking remains critical

Fierce Healthcare

Industry Voices—As healthcare's labor shortages worsen, masking remains critical pminemyer Fri, 04/07/2023 - 16:03

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Sustained-release chemotherapy has potential for bladder cancer

European Pharmaceutical Review

A new, sustained-release chemotherapy delivery device inserted into the bladder, facilitated tumour response, a study has reported. The treatment was given to elderly patients with advanced bladder cancer who were medically unfit for standard treatment. The intravesical device, TAR-200, provides continuous, low-dose, local delivery of gemcitabine chemotherapy. “TAR-200 was generally safe, well tolerated, and had beneficial effects on bladder cancer outcomes,” commented lead author Dr

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Layoffs are ramping up among hospitals and health systems. Here are 34 examples from 2023

Fierce Healthcare

Layoffs are ramping up among hospitals and health systems.

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The Ascendancy of Social Media: Fitting Pharma Brand Teams Into the Conversation Mix

PharmExec

Marketing leaders discuss the powerful role life sciences companies can play in the expanding digital landscape for healthcare communications—as “one of the helpful voices” in driving the customer and patient conversations that matter most.

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What’s New With Continuous Glucose Monitors

Drug Topics

Continuous glucose monitors are poised to change diabetes management for patients.

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Happy Easter Weekend!

OctariusRx

Happy Easter Weekend from all of us at OctariusRx! Wishing you a season filled with peace, joy, and beautiful weather. Happy Easter! The Consultant Pharmacists at OctariusRx provide guidance on safe medication management, survey readiness and cost savings to ambulatory healthcare facilities/surgery centers , senior care facilities and pharmacies.

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Walmart to expand electric vehicle charging network

Drug Store News

Walmart plans to install new fast-charging stations at thousands of Walmart and Sam’s Club locations across the country.

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Clovis sells off remaining assets—including cancer drug Rubraca—for $70M-plus

Fierce Pharma

Clovis sells off remaining assets—including cancer drug Rubraca—for $70M-plus kdunleavy Fri, 04/07/2023 - 10:33

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Baylis & Harding launches Kindness+ at Target

Drug Store News

The Kindness+ line includes two plant-based hand cleansers and moisturizers infused with hyaluronic acid and vitamin C.

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