Fri.Mar 22, 2024

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Psilocybin Side Effects Found to be Tolerable, Resolve Within 2 Days

Drug Topics

Results from a meta-analysis on the side of effects of the psychedelic psilocybin were presented at the 2024 American Pharmacists Association Annual Meeting & Exposition.

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FDA Expands Label for Bempedoic Acid to Reduce Cardiovascular Risk, With or Without Statins

Pharmacy Times

Bempedoic acid (Nexletol; Esperion) and bempedoic acid and ezetimibe (Nexlizet; Esperion) are the only LDL-C lowering non-statin drugs indicated for primary prevention patients.

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FDA authorizes new drug to protect immune compromised from Covid-19

STAT

The Food and Drug Administration on Friday authorized a new antibody to protect immunocompromised individuals against Covid-19.  The drug, known as Pemgarda and marketed by the biotech Invivyd, is the first such drug to become available since the agency pulled AstraZeneca’s Evusheld off the market in January 2023. New Omicron variants had rendered Evusheld ineffective.

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As Cannabis Use Increases, Pharmacists Must Be Prepared to Counsel Patients

Pharmacy Times

As more states have legalized cannabis use—both medicinal and recreational—Sera said pharmacists’ roles in counseling will become even more important.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Veterans Reported Loss of Everyday Functioning After COVID-19 Pandemic

Drug Topics

Researchers aimed to address the adverse effects of veterans with COVID-19 diagnoses 18 months after infections were documented.

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Navigating Cannabis in Pharmacy Practice: State Legislation and Contraindications for Patient Use

Pharmacy Times

Pharmacists can educate patients on current clinical evidence of cannabis’s therapeutic benefit, as well as cannabis’s complexities, risks, and potential adverse effects.

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Pharmacists Address Their Role in Adolescent Vaping Education

Drug Topics

According to posters presented at the 2024 American Pharmacists Association Annual Meeting and Exposition, pharmacists wish to play a bigger role in educating young people about the risks of vaping.

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Pregnancy increases biological age — but recovery and breastfeeding can undo the damage, study finds

STAT

Pregnancy is a known stressor on the body. But a new study published on Friday in Cell Metabolism found that while pregnancy accelerates the body’s biological clock, much of that effect is reversed after delivery, especially in people who breastfeed. The results add to growing evidence that molecular aging, a process by which our cells accrue damage and dysfunction over time, doesn’t progress in a linear fashion — nor only forward.

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SXSW24: Better communication, collaboration, reimbursement needed to improve cancer care

Fierce Healthcare

Uncomfortable waiting rooms. Revealing hospital gowns. Confusing insurance. Exhausting travel between appointments. | Oncology was a major focus at this year’s SXSW conference. Across multiple sessions, clinicians and patient advocates called for better access to specialty care, more thoughtful communication with patients and continued collaboration across stakeholders.

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STAT+: Drug development was once a marathon. New tools and timelines are turning it into a sprint

STAT

Drug development is more of a sprint than a marathon these days, thanks to more and better ways to target underlying biology and a more nuanced interpretation of precision medicine, three biotech leaders said at the STAT Breakthrough Summit East in New York Thursday. “We used to say, well, you may spend five years in the research phase, another five in development.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Novo Nordisk closes in on EU approval for its once-weekly insulin Awiqli

Fierce Pharma

Sales are booming for Novo Nordisk’s GLP-1 treatments for diabetes and obesity. But that doesn’t mean the Danish company has moved on from its previous generation of blood sugar modulators. | With a positive recommendation from Europe’s Committee for Medicinal Products for Human Use (CHMP), Novo has come a step closer to bringing its revolutionary Awiqli (once weekly basal insulin icodec) to the market.

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STAT+: Despite new Wegovy coverage, Medicare patients may face high drug costs and other hurdles

STAT

Medicare confirmed this week that it will cover Novo Nordisk’s obesity drug Wegovy if prescribed to prevent heart problems, but policy experts said Medicare patients are still likely to encounter significant barriers getting access to the highly popular and expensive drug. Medicare previously wasn’t reimbursing for Wegovy, since the federal payer is legally barred from covering weight loss drugs.

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St. Louis' SSM Health, BJC Health System launch joint venture to iron out the wrinkles of laundry service

Fierce Healthcare

Though it may sound benign, unexpected laundry service interruptions can leave a deep stain on hospital care delivery. | The large nonprofit systems will jointly own and operate a regional laundry facility that will deliver 80 community jobs and 35 million pounds of clean hospital linens per year.

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Male birth control research wins audience over at STAT Madness event

STAT

What happens when too many excellent, pioneering researchers enter a room? A little madness. That’s what attendees at the Breakthrough Summit East in New York had on their hands Thursday, as four participants presented their work in this year’s STAT Madness competition — an annual March Madness bracket-style battle to find the best innovation in science and medicine.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Slideshow: Assessing the COVID-19 Pandemic After its 2020 Peak

Drug Topics

Four posters presented at the American Pharmacists Association Annual Meeting and Exposition explored how individuals and health care providers have been handling the COVID-19 pandemic.

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Arches Medical Partners buys 11 primary care clinics from VillageMD

Fierce Healthcare

Walgreens-owned VillageMD sold 11 primary care clinics in Rhode Island to Boston-based Arches Medical Partners. | Walgreens-owned VillageMD sold 11 primary care clinics in Rhode Island to Boston-based Arches Medical Partners.

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Slideshow: Pharmacist Interventions Are Key in Addressing the Mental Health Crisis

Drug Topics

Four posters presented at this year’s American Pharmacists Association Annual Meeting & Exposition assessed the potential impact of pharmacist interventions on improving mental health outcomes.

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The 3 biggest mistakes we keep making in clinical operations

pharmaphorum

Explore the three major mistakes commonly made in clinical operations that impact patient care, clinical research, and data integrity. Learn how to avoid these pitfalls for successful clinical operations.

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Italfarmaco nabs FDA approval for new Duchenne med, teeing up sparring match with Sarepta

Fierce Pharma

At a watershed moment for Duchenne muscular dystrophy (DMD) treatment, privately held Italian drugmaker Italfarmaco has added a new therapeutic option to the armamentarium against the debilitating | At a watershed moment for Duchenne muscular dystrophy treatment, privately held Italian drugmaker Italfarmaco has added a new therapeutic option to the armamentarium against the debilitating muscle-wasting disorder.

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Pharmacists Make Positive Impact Through Clinical Interventions

Pharmacy Times

Providing evidence-based literature and resolving medication-related problems are strategies for improving acceptance of clinical recommendations

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Opinion: STAT+: Medical devices makers are trying to take a page from Uber’s playbook

STAT

In a recent survey of U.S. companies, medical device makers reported spending $31 million on average to bring a new product to market under the Food and Drug Administration’s 510(k) pathway for those similar to devices already approved. These costs balloon to more than $90 million for new Class III devices that progress through the more rigorous premarket approval pathway.

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Lilly CEO reaffirms commitment to Chinese market amid US threat against local biotechs

Fierce Pharma

At a time of heightened geopolitical tensions between the U.S. and China, Eli Lilly’s CEO said the Indianapolis-based company remains committed to the Chinese market. | David Ricks’ visit to China comes as Lilly has several key drug applications under review at local regulators.

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STAT+: How biotech investors spot opportunity when stocks are down — and up

STAT

Following a blockbuster year of dealmaking and a recent uptick in biotech stocks, top investors see more good news on the horizon. Driving the momentum? Economics 101. Biotechs rely on borrowing capital, which is a more tenuous task when interest rates are high. But interest rates have most likely peaked, with Federal Reserve officials signaling earlier this week they expected to make three cuts this year.

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Comprehensive Medication Reviews Can Help Improve Adherence in Patients With T2D

Drug Topics

Medication therapy management can also increase the likelihood of using statins in this population.

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STAT+: How a for-profit health system’s push to expand ended in disappointment for a tiny island nation

STAT

Protesters in the tiny Mediterranean nation of Malta converged last October on the 18th-century Baroque palace housing the prime minister’s offices chanting “thieves,” and unfurled a massive banner on the steps emblazoned with the words: “Bring back the €400 million now.” The object of their furor wasn’t just the government.

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How "Scope Creep" Can Save Health Care

Drug Topics

In its ongoing campaign against “scope creep,” the American Medical Association argued that pharmacists don’t receive enough training. Physicians and pharmacists alike disagree.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.  That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Does Lexapro make you tired?

The Checkup by Singlecare

Lexapro , the brand name for escitalopram, is an antidepressant that is approved by the U.S. Food and Drug Administration (FDA) for the treatment of mental health conditions, including major depressive disorder and generalized anxiety disorder in adults, young adults, and pediatric patients. It is a selective serotonin reuptake inhibitor (SSRI) that works by blocking the reabsorption of serotonin into the brain—increasing the amount present.

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FDA approves Idorsia’s Tryvio for treatment of high blood pressure

Pharmafile

Idorsia has announced that the US Food and Drug Administration (FDA) has approved Tryvio (aprocitentan) for the treatment of hypertension in combination with other antihypertensive drugs, to lower blood pressure in adult patients who are not adequately controlled on prior treatments. The drug is an ‘endothelin receptor antagonist that inhibits the binding of endothelin (ET)-1 […] The post FDA approves Idorsia’s Tryvio for treatment of high blood pressure appeared first on Pharmafile.

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Oral medication for eczema: Types, benefits & side effects

The Checkup by Singlecare

Eczema is a type of dermatitis, a group of medical conditions that cause inflammation of the skin. People with eczema have dry, itchy skin. There are several types of eczema, the most common of which is atopic dermatitis. According to Cleveland Clinic , eczema is common and affects 31 million people in the United States. Anyone of any age can be affected, although symptoms generally start in childhood and persist through lifetime.

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Heart claims unlock Medicare coverage of obesity drugs

pharmaphorum

Medicare has loosened restrictions on the reimbursement of obesity drugs, thanks to clinical data showing they can improve cardiovascular outcomes, but their price could be up for negotiation.

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EU adviser says Illumina merger was not problematic

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hi, it’s Meghana. Today, Illumina finally finds an advocate in the EU, a CRISPRed pig kidney is transplanted into a living human, and more.

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Digital diabetes tools ‘of little benefit and raise costs’

pharmaphorum

First report from PHTI concludes that digital health technologies for diabetes management deliver minimal clinical benefit and raise healthcare costs

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Abortion law emergency-exemption guidance proposed by Texas Medical Board

STAT

The Texas Medical Board, responding to pressure from the state Supreme Court and widespread uncertainty among physicians, proposed draft guidance Friday in an attempt to clarify what constitutes emergency grounds for a legal abortion. A summary of the proposed rules were read out by board president Sherif Zaafran, who summarized the proposed rules at a regularly scheduled meeting.

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