Tue.Aug 08, 2023

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Zuranolone Approved as First, Only Oral Medication to Treat Postpartum Depression

Drug Topics

Approximately 1 in 8 women in the United States experience postpartum depression.

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Nose Picking Among Health Care Workers Associated With Increased Risk of SARS-CoV-2

Pharmacy Times

Study results showed no significant association between those who bite their nails and SARS-CoV-2 infection, in addition to a lower rate of infection for those who wear glasses compared to those who don’t wear glasses.

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Morning RX: August 8, 2023

Drug Topics

Omicron EG.5 COVID-19 Variant takes hold in the US, new inclusive blood donation guidance goes into effect, and the national uninsured rate reaches a new all-time low.

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Inappropriate Medication Use Among Older Adults On-The-Rise in Outpatient Setting

Pharmacy Times

Adults aged 80 years and older and those living in areas with worse economic conditions are more likely to receive potentially inappropriate medications in the outpatient setting, which may be associated with cognitive impairment.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Chronic Pain Prevalence High Among Women With HIV

Drug Topics

Chronic pain is among the comorbidities for people diagnosed with HIV, but there has been a lack of data on the prevalence and risk factors in women.

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Depression, Anxiety Linked to Increased Risk of Developing Lung, Smoking-Related Cancers

Pharmacy Times

Though an association was found between depression and anxiety and lung cancers, there were no connections found to overall, breast, prostate, colorectal, and alcohol-related cancers.

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More Trending

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Structured Surveillance Rarely Used for Patients with Subsegmental Pulmonary Embolism Despite Recommendations

Pharmacy Times

In addition to the low use of structured surveillance overall, modified CHEST criteria only identified a small portion of patients with subsegmental pulmonary embolism eligible to receive structural surveillance.

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Senators push IRS to launch nonprofit hospital probe

STAT

WASHINGTON — A bipartisan group of senators wants federal tax regulators to probe nonprofit hospitals’ compliance with community benefit requirements, ratcheting up a longtime campaign to hold the tax-exempt providers accountable. Nonprofit hospitals are often subsidized by state or federal funding and exempt from many taxes. In exchange, they are required to aid their surrounding area through public health programs and providing free or discounted care to low-income patients.

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Study: School Districts With Greater Social Vulnerability Show Higher Rates of SARS-CoV-2

Pharmacy Times

The findings suggest that varying precautions and factors affected the transmission rates in schools in different periods of the pandemic.

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Half of people worldwide at risk of developing mental health condition by age 75, per new study

STAT

By the age of 75, half of people worldwide can expect to experience a mental health disorder, according to the finding of a large study of more than 156,000 people across 29 countries. The study, published last week in The Lancet Psychiatry , analyzed answers that participants provided between 2001 and 2022 in response to a World Health Organization survey designed to assess the prevalence of major mental health disorders.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Burden of Aging-Related Comorbidities Higher in Women, Those with HIV

Pharmacy Times

The burden of aging-related comorbidities was higher across every age category in women compared to men, and increased with age.

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Mint.com founder's health tech company launches AI tool to translate medical jargon for patients

Fierce Healthcare

Most patients have had those moments when they try to decipher their doctor's medical notes. Myalgia? Epistaxis? F/U? It can seem like a foreign language to a layperson. | Health tech company Vital launched an AI-powered doctor-to-patient translator to instantly turn highly technical medical terminology into plain language.

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Proposed FDA Rule on Patient Medication Information Seeks to Address Prescription Misuse, Nonadherence

Pharmacy Times

Improved prescription information could help consumers make better health care decisions and result in cost savings.

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Are there foods to avoid when taking Cymbalta?

The Checkup by Singlecare

Cymbalta ( duloxetine ) is a type of antidepressant known as a serotonin and norepinephrine reuptake inhibitor (SNRI). It’s used to treat depression and anxiety as well as chronic pain conditions like fibromyalgia and nerve pain caused by diabetes. SNRIs work similarly to selective serotonin reuptake inhibitors (SSRIs), but they also increase the amount of the neurotransmitter norepinephrine in the brain (SSRIs only increase serotonin).

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: Novo’s obesity drug Wegovy lowers cardiovascular risk by 20%, landmark trial finds

STAT

Novo Nordisk’s obesity drug Wegovy cut the risk of major heart complications by 20% in a closely watched trial, results that could streamline insurance coverage and spur even greater demand for the highly popular therapy. The milestone Select trial of about 17,500 patients with obesity and heart disease is the first to show that a weight loss medication leads to long-term cardiovascular benefits.

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Novo Nordisk posts 'best-case scenario' cardio outcomes data for star obesity drug Wegovy

Fierce Pharma

Novo Nordisk has been riding the momentum of weight loss drug Wegovy ever since it stormed onto the market in 2021, creating widespread hype and even some supply shortfalls. | In a large phase 3 trial, Wegovy cut the risk of major adverse cardiovascular events by 20% compared with placebo and standard of care, Novo said Tuesday. Specifically, investigators measured Wegovy's 2.4-mg dose for its ability to cut the risk of a cardio death, heart attack or stroke.

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Opinion: What ‘The Bear’ can teach us about hospitality in medicine

STAT

The FX/Hulu show “The Bear” transports viewers inside the tense world of restaurants.  In Season 2’s seventh episode, “Forks” (no real spoilers here, I promise), the uncooperative and defensive Richie (Ebon Moss-Bachrach), who has mostly worked in a no-frills sandwich shop, is given the opportunity to stage (basically a short unpaid internship) in a fancy restaurant.

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With sales in free fall, Bayer's new CEO Anderson considers structural change

Fierce Pharma

It took Bayer’s new CEO Bill Anderson about 20 seconds into his first quarterly conference call to go against the grain. | In his first quarterly earnings call since taking over as CEO at Bayer, Bill Anderson faced several questions about the structure of the company. He said to stay tuned until early 2024. The company reported a 14% decline in revenue for the quarter, with all three business sectors seeing a drop in sales.

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More US counties have become maternity care deserts since 2020, March of Dimes finds

Fierce Healthcare

There has been a 2% rise in maternity care deserts since 2020—meaning 1,119 additional counties, a new analysis suggests. | More than a third of all U.S. counties were classified as maternity care deserts. Nationwide, 5% of counties have less maternity access than two years ago, the report found.

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Ransomware attack shuts down hospital emergency rooms in several states

STAT

You’re reading the web edition of STAT Health Tech, our guide to how tech is transforming the life sciences.  Sign up to get this newsletter  delivered in your inbox every Tuesday and Thursday.

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Health system execs on board with generative AI, but few have a plan in place

Fierce Healthcare

Health system executives say they’ve been convinced by generative AI and its potential to shoulder some of healthcare’s biggest burdens, yet very few have a plan in place to make it happen, Bain &a | A new poll outlines health systems' highest priority use cases for the trendy technology as well as some of the hurdles leadership says are hampering implementation at their organizations.

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Embracing Programmatic Advertising to Enhance Targeting of HCPs

PharmExec

The precision of programmatic advertising is reshaping the way life sciences brands engage with healthcare professionals, offering enhanced personalization, scale, and optimization in today's digital landscape.

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Industry Voices—Meet the 5th 'C' of primary care: Corporate America

Fierce Healthcare

In 2021, Walgreens Boots Alliance acquired VillageMD for $5.2 | By 2030, it is projected that 30% of U.S. primary care will be owned by non-traditional players like Amazon and Walmart.

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STAT+: More regulation could be coming for drug ads

STAT

WASHINGTON — Government regulators may soon decide whether to crack down on distracting visuals in television drug commercials or require subtitles about side effects, a regulation that’s been 13 years in the making. White House budget experts are reviewing changes to the regulation of broadcast drug advertisements that the Food and Drug Administration proposed in 2010 , according to the Office of Management and Budget website.

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Emergent to lay off 400 staffers, eliminate executive position in pivot away from contract manufacturing

Fierce Pharma

Big changes are brewing at Emergent BioSolutions, as the beleaguered contract manufacturer puts its CDMO business on the back burner in a bid to shore up its core medical countermeasures and Narcan | Emergent is de-emphasizing its focus on its CDMO services business. As part of the move, Emergent will scale back operations at its Bayview facility in Baltimore, Maryland, as well as its plants in Canton, Massachusetts, and Rockville, Maryland.

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Dexpramipexole found to significantly lower absolute eosinophil count in asthma

Hospital Pharmacy Europe

Oral dexpramipexole significantly reduced blood absolute eosinophil count (AEC) after 12 weeks compared to placebo in patients with eosinophilic asthma, highlighting the potential value of oral therapy for these patients. The EXHALE trial, published in the Journal of Allergy and Clinical Immunology , was a randomised, double-blind, placebo-controlled proof-of-concept trial, in adults with inadequately controlled moderate to severe asthma and an AEC greater than or equal to 300/μL.

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Doximity lays off 10% of workforce, stock slides as company downgrades revenue guidance

Fierce Healthcare

Doximity, a digital platform for medical professionals, cut its workforce by 10%, or 100 employee positions, and downgraded its revenue guidance as it faces economic pressures and slowing sales am | Doximity, a digital platform for medical professionals, cut its workforce by 10%, or 100 employee positions, and downgraded its revenue guidance as it faces economic pressures and slowing sales among its pharmaceutical customers.

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From windows to wall art, hospitals use virtual reality to design more inclusive rooms for kids

STAT

BERKELEY, Calif. — For many young patients, harsh lights, bare walls, and windows facing parking lots or brick buildings make already painful hospital visits more unpleasant, stoking fear and uncertainty instead of hope. Often, those patients say, it makes recovery harder. Their perspectives — historically overlooked in hospital design — are at the heart of a budding movement to make architecture more inclusive for the people who actually spend time there.

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Semaglutide demonstrates cardiovascular benefit

European Pharmaceutical Review

Headline results from Novo Nordisk’s “landmark” SELECT trial in cardiovascular outcomes has demonstrated a 20 percent reduction in major adverse cardiovascular events (MACEs) for semaglutide 2.4mg (Wegovy ® ) compared to a placebo. “People living with obesity have an increased risk of cardiovascular disease but to date, there are no approved weight management medications proven to deliver effective weight management while also reducing the risk of heart attack, stroke or cardio

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STAT+: Wegovy cardiovascular study has doctors seeing new possibilities in weight loss drug

STAT

The momentum around weight loss drugs is about to get even bigger in the wake of Novo Nordisk’s announcement that its semaglutide drug Wegovy cut the risk of cardiovascular disease by 20% in its large SELECT trial. The full results of the study, funded by Novo, will be presented at the American Heart Association meeting in November. Doctors and researchers say they expect the findings to have a big impact on how clinicians approach the treatment of both obesity and cardiovascular disease,

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Hims & Hers plans to launch weight loss business by year-end as revenue growth streak continues in Q2

Fierce Healthcare

Hims & Hers saw its top line jump 83% in the second quarter, driven by strong growth of its online health and wellness business. | Hims & Hers boosted the lower end of its revenue guidance by $20 million to between $830 million and $850 million for the year and also announced it was jumping into the booming weight loss market.

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STAT+: Pharmalittle: Novo’s Wegovy obesity drug lowers cardiovascular risk in key trial; Nektar accuses Lilly of ‘misconduct’ in development deal

STAT

Top of the morning to you. Gray skies are hovering over the Pharmalot campus right now, but our spirits remain sunny, nonetheless. Why? We will trot out a bit of insight from the Morning Mayor, who would say “Every new day should be unwrapped like a precious gift.” To celebrate the notion, we are brewing still more cups of stimulation and invite you to join us.

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Viatris plans to reveal 'significant' divesture this quarter as it moves ahead with strategic revamp

Fierce Pharma

As Viatris looks to shed its reputation as a company focused solely on generics and reach $1 billion in eye care sales, the drugmaker has laid out a near-term goal to close three divestitures. | The company expects to announce three divestures this year, with one coming in the current quarter. After that, Viatris believes it can move into phase 2 of its return to growth strategy, which includes building out its growing eye care business.

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Engagement Ring Q&A

The Luxe Pharmacist

Hi loves! First, I just wanted to say thank you from the bottom of our hearts for the outpouring of love and well wishing surrounding our engagement! We couldn’t be happier or more excited and we are so blessed to share it with you. Also, huge thank you to everyone who submitted questions on Instagram, this post is based on everything you asked!

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