Tue.Dec 26, 2023

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Slideshow: 2023 Biologic Product Approvals

Drug Topics

Biologic approvals ranged from gene therapies for hemophilia A to a cellular therapy to treat type 1 diabetes.

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STAT+: Complications spiked 25% in hospitals bought by private equity

STAT

There’s ample evidence that private equity buyouts in health care drive up costs. A new study shows quality declines, too. Hospitals acquired by private equity saw a 25% uptick in adverse events compared with controls, according to a new study released today in the Journal of the American Medical Association. The findings add to an accumulating body of literature underscoring the harm that occurs when financial investors take over health care providers — not only hospitals, but nur

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What are potassium-rich foods?

The Checkup by Singlecare

About potassium | Daily intake of potassium | Potassium-rich fruits | Vegetables | Meat and seafood | Nuts and legumes | Other potassium-rich foods | Meal plan Have you ever woken up in the middle of the night with an awful leg cramp or felt faint after a light workout? These may be signs that your body is missing an important mineral: potassium. The good news for those with low potassium levels is that you can find it in many of the foods at your local grocery store.

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STAT+: 3 CRISPR advances to watch in 2024

STAT

Life in the CRISPR lane tends to move at lightning speed. This year saw the first-ever approval of a medicine based on the gene editing technology, barely more than a decade after publication of its first demonstration by Nobel laureates Jennifer Doudna and Emmanuelle Charpentier. The landmark decision paves the way for in vivo therapies, which edit cells inside the body, to reach patients, as well as treatments based on more efficient genome editors with fancier DNA-altering tricks up their sle

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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What causes lower back pain and black stool? Related conditions and treatments

The Checkup by Singlecare

Lower back pain and black stool causes are not usually connected. Lower back pain is very common and can be caused by poor posture, heavy lifting, osteoarthritis, menstrual cramps, and more. Black stool can be caused by certain medications, foods, or supplements, but it can also be a sign that you’re bleeding from inside your gastrointestinal (GI) tract.

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STAT+: New weight loss drugs have proven their effectiveness. Now researchers want to know how to best use them

STAT

LONDON — Starting in the new year, a team of researchers in the U.K. and Denmark will begin recruiting patients for a study driven by a pressing question in medicine: How should new obesity medications be incorporated into regular practice? Trials have demonstrated that the powerful drugs can help people shed weight in dramatic ways, but clinicians are still trying to sort out how to best use them.

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STAT+: Bristol Myers will pay $4.1 billion for cancer startup RayzeBio

STAT

Bristol Myers Squibb will pay $4.1 billion for RayzeBio, the companies said Tuesday, buying into the fast-growing field of using targeted doses of radiation to treat cancer. RayzeBio, which raised about $350 million in a September initial public offering, is working in radiopharmaceuticals , which pair the tumor-killing power of radiation with the precision of targeted cancer therapies.

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BMS agrees to acquire Karuna Therapeutics for $14bn

Pharmaceutical Technology

Bristol Myers Squibb (BMS) has signed a definitive agreement for the acquisition of Karuna Therapeutics for $14bn in cash.

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Opinion: Does food as medicine help patients with diabetes? Here’s what a new clinical trial says

STAT

Food-as-medicine programs that address food insecurity and diet-related chronic diseases have drawn widespread attention from policymakers , payers, and health care providers. But what is the evidence that such programs work as intended? Some research suggests that food as medicine can improve health and lower health care costs, but until now there has been little evidence from randomized clinical trials.

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Unilever set to acquire K18

Drug Store News

Unilever announced the signing of an agreement to acquire biotech hair care brand K18.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: 3 medtech trends to watch in 2024

STAT

It’s been a slow year for medtech. Major deals in 2023 were scarce, funding was hard to come by, and valuations were down. On the policy side, the industry grappled with changing AI regulations, reimbursement woes, and device sterilization rules. Here are three political and market forces that shaped the medtech industry last year, and are worth paying attention to in 2024: Lobbying power of AI, software-enabled devices Medtech lobby AdvaMed announced earlier this month that the major med

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Investing in healthspan: A prescription for prosperity

pharmaphorum

Exploring the powerful collaborations between scientists, investors, and the medical community in finding breakthrough treatments for major diseases, and the notion of 'healthspan'

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COTA's real-world dataset aims to capture accurate cancer mortality rates

Fierce Healthcare

Knowing patient survival rates is critical to informing research and care delivery, particularly in the oncology space. But what if survival data is inaccurate or incomplete? | In a recent study, COTA looked at how its data compares to that of the National Death Index and found exact date concordance in 88% of patients.

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Exploring the reasons behind increasing burdens on clinical research sites

pharmaphorum

In the first of a five-part festive instalment of the pharmaphorum podcast, web editor Nicole Raleigh speaks with Advarra’s chief product officer, Elisa Cascade, about the reasons behind increasing burdens on clinical research sites over the last five years.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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MRI costs: What you’ll pay with and without insurance

The Checkup by Singlecare

In the United States, healthcare pricing isn’t often straightforward. To fix this issue, the Centers for Medicare and Medicaid Services (CMS) introduced a new hospital price transparency rule that went into effect on January 1, 2021. The ruling requires hospitals to publish their pricing in a consumer-friendly format. Despite this ruling, finding and understanding a hospital’s pricing information is still challenging.

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Top 5 Pharmacy Times Clostridioides difficile Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read Clostridioides difficile-related articles on Pharmacy Times in 2023.

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A Record Year for Disease Elimination

BioPharm

WHO provides a look at the world’s health as the agency turns 75.

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Top 5 Pharmacy Times Cardiovascular Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read cardiovascular-related articles on Pharmacy Times in 2023.

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7 potential benefits of dandelion root

The Checkup by Singlecare

You would almost certainly recognize a wild plant belonging to the Taraxacum genus that has been used for centuries in traditional medicine. You probably know it by a different name, however: dandelion. People have long used different parts of this flowering plant for a variety of medicinal purposes. In fact, the root has different benefits than the benefits of the leaves and flowers.

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Top 5 Pharmacy Times Heart Failure Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read heart failure-related articles on Pharmacy Times in 2023.

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What causes eyebrow headaches? Related conditions and treatments

The Checkup by Singlecare

Have you ever felt pain specifically around or behind one or both eyebrows? Eyebrow pain can be associated with various conditions, such as inflamed sinuses or migraine, among others. Eyebrow headaches due to sinus infections may be temporary, while eyebrow headaches caused by an underlying medical condition may recur. This article will discuss various causes of eyebrow pain, as well as treatment options.

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AZ makes another cell therapy play with $1.2bn Gracell buy

pharmaphorum

AstraZeneca agrees a $1.

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Right temple headache: Most likely causes and treatment

The Checkup by Singlecare

Getting relief from a headache requires figuring out what’s causing it in the first place. The location of your headache can help you determine its type, which in turn helps determine the underlying cause and how to find relief. Headaches on the right side of the head can be caused by muscle tension, migraine, sinus inflammation, and more. They can be remedied by over-the-counter (OTC) painkillers, prescription migraine medication, stretching, or hot or cold compresses.

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AstraZeneca buys Chinese cancer therapy firm Gracell for $1.2bn

The Guardian - Pharmaceutical Industry

Gracell Biotechnologies acquisition marks China’s growing importance to the Anglo-Swedish drugmaker AstraZeneca has struck a deal to buy a Chinese cancer therapy company for up to $1.2bn (£950m), as Britain’s biggest drugmaker expands its footprint in its second-largest market. The Anglo-Swedish pharmaceutical firm announced on Tuesday it would acquire Gracell Biotechnologies, which is focused on a type of cancer therapy known as CAR-T that modifies a patient’s cells to fight the disease.

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Why does my scalp hurt? Related conditions and treatments

The Checkup by Singlecare

The most common causes of scalp pain and tenderness are inflammation, headaches, nerve-related diseases, and fungal infections. And, in people who have a sensitive scalp, some irritants in hair products like shampoos, relaxers, soaps, oil, dyes, and even changes in weather can contribute to that feeling of pain. Depending on the cause, scalp pain may feel like pressure or a numbing, stabbing, or burning pain.

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Wisp intros Lift for Him and Her

Drug Store News

Wisp Lift for Him and Her is a doctor-formulated libido booster that works to help elevate desire and drive, the company said.

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How much is Keppra (levetiracetam) without insurance?

The Checkup by Singlecare

Is Keppra covered by insurance? | How much does Keppra cost without insurance? | How to get Keppra without insurance Keppra is a brand-name prescription anticonvulsant. The generic version is levetiracetam. Both are FDA-approved to treat partial or generalized tonic-clonic seizures in adults and some children. They’re also used to treat children with myoclonic seizures.

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Top 5 AI Stories of 2023

PharmExec

As this exciting technology exploded in 2023, Pharm Exec was there to cover it all.

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6 common patient questions about insulin biosimilars

The Checkup by Singlecare

For many patients with diabetes, particularly those with Type 1 diabetes, insulin is a key part of managing glucose levels and preventing complications. However, many patients may have trouble getting the insulin they need, whether due to high costs or limited options. While many brand-name medications are widely available as cheaper generic alternatives, such options are often less accessible for insulin products.

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Columbia Skincare reformulates antiseptic powders, debuts sun care line

Drug Store News

Columbia Skincare announced a patented new formula of its talc-free antiseptic powders and a collection of sun care products.

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ABBV-400 by AbbVie for Head And Neck Squamous Cell Carcinoma (HNSC): Likelihood of Approval

Pharmaceutical Technology

ABBV-400 is under clinical development by AbbVie and currently in Phase I for Head And Neck Squamous Cell Carcinoma (HNSC).

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Top 5 Most Popular Cold Chain Articles of 2023

Pharmaceutical Commerce

Items in this sector ranged touched on topics such as pharma shipping, container technology, and sustainability.

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Exarafenib by Kinnate Biopharma for Non-Small Cell Lung Cancer: Likelihood of Approval

Pharmaceutical Technology

Exarafenib is under clinical development by Kinnate Biopharma and currently in Phase I for Non-Small Cell Lung Cancer.

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Top Social Media Trends of 2023

PharmExec

Five trends in pharmaceutical marketing from the past year.

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