Tue.Nov 21, 2023

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Unveiling Progress and Challenges: C diff Awareness Among Medical Professionals

Pharmacy Times

Christian John Lillis, co-founder and executive director at Peggy Lillis Foundation, discusses the role of the pharmacist in education that advances C diff awareness in the medical community.

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Racial Discrimination in Cancer Care Setting Impacts Black Patients Long-Term

Drug Topics

Black patients reported associating negative emotions with experiences of racial discrimination long after the experience concluded, raising concerns about long-term health outcomes.

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Prevention, Treatment for Migraine Rapidly Evolves, Calling for Development of Novel Drugs

Pharmacy Times

Zavegepant (Zavzpret; Pfizer) is the first and only only CGRP receptor antagonist as a nasal spray for the acute treatment of migraine in adults with and without aura approved by the FDA.

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Moderna loses a COVID vaccine patent in Europe amid heated clash with BioNTech, Pfizer

Fierce Pharma

With litigation spanning many countries, the COVID-19 vaccine giants remain engaged in a heated patent war. | Moderna pledged to appeal after the European Patent Office ruled one of its patents invalid in the intellectual property battle that spans multiple countries.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Current Trends, Treatment Strategies for C diff Infection

Pharmacy Times

Paul Feuerstadt, MD, FACG, AGAF, discusses insights in current treatment practices for CDI at the Peggy Lillis Foundation’s 2023 State of C diff Virtual Town Hall.

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How the shakeup at OpenAI underscores the need for AI standards in health care

STAT

The leadership turmoil within OpenAI, the maker of ChatGPT, is triggering calls for stepped-up efforts to establish standards for how generative AI is used across the health care industry, where experts worry that one or two companies could end up with too much control. Microsoft was already a driving force behind efforts to deploy generative AI in health care.

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Opinion: Filling 12-month prescriptions is one practical way to help the pharmacist crisis

STAT

Pharmacies could be called the most “rock solid” entity in our health care system. Even before Covid, pharmacies were held in high esteem; during the pandemic, they raised their game by making it easy for tens of millions of Americans to get vaccinated, fulfilling a long-standing ambition of pharmacists to provide more expansive clinical services.

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How Prisma Health unified digital health tech to boost patient engagement, slash no-shows

Fierce Healthcare

Navigating the healthcare system often requires using different websites, mobile apps and phone calls to find providers and make appointments. | The health system has seen a 10x increase in downloads of the Prisma Health Go app, from 40 to up to 400 downloads per day. The health system also reports a 33% reduction in patient no-shows in one year and estimates $8 million in cost savings as a result of slashing the no-show rates.

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Opinion: What Rosalynn Carter understood about mental health

STAT

Few people leave the world with as much grace or influence as Rosalynn Smith Carter, who died Sunday at the age of 96. While she called her autobiography “The First Lady of Plains,” to many she was also the first lady of mental health reform. Decades ago, she took bold stances on mental health topics that, today, have become conventional wisdom: Mental health is health, stigma is deadly, and people with mental illness deserve to be part of society instead of hidden away in overcrow

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Texas accuses Pfizer and contract manufacturer of providing ineffective ADHD drug to state's Medicaid program

Fierce Pharma

Texas has accused Pfizer and manufacturer Tris Pharma of knowingly providing compromised ADHD medicine to a state Medicaid program for children of low-income families. | In its lawsuit, Texas says the companies knew that deficient manufacturing processes compromised the effectiveness of Quillivant XR. The lawsuit further accuses the companies of manipulating quality-control testing from 2012 to 2018 to ensure samples received passing grades.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: How the CEO of the largest medical device accelerator molds medtech startups

STAT

If Paul Grand weren’t the CEO of MedTech Innovator, the largest medical device accelerator in the world, he might have been a keychain salesman. Maybe a producer of the X-Files. Or even invented Quizlet. The son of a teacher and a dentist, Grand graduated from selling neighbors keychains and washing cars as a little kid to programming software that made his parents’ lives easier.

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Keeping Our Infant and Older Adult Populations RSV-Free This Season

Pharmacy Times

It will be interesting to see RSV hospitalization rates over this upcoming season following the rollout of RSV vaccines and monoclonal antibody administration.

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STAT+: Delay of eye drop recall highlights FDA’s impotence on the issue

STAT

WASHINGTON — It took nearly three weeks for a maker of eye drops to recall its products after the Food and Drug Administration requested a recall. There have been no reports of injuries, but some key lawmakers are arguing the time it took the FDA to coax a voluntary recall shows the agency should be given the power to force them. Eye drops must be sterile because drugs applied to eyes bypass some of the body’s natural defenses.

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Talkspace inks $26M contract with NYC to provide free mental health services to teens

Fierce Healthcare

Online therapy company Talkspace with provide free virtual mental health services to more than 400,000 adolescents and teens in New York City. | Talkspace CEO Jon Cohen, M.D. believes the company has a "moral imperative" to help address teen mental health. There's also a smart business case for building out its virtual mental health offerings for adolescents and teens.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Texas AG sues Pfiz­er and Tris Phar­ma for adul­ter­at­ed ADHD drug

Pharmaceutical Technology

Texas AG has sued Pfizer and Tris Pharma for providing adulterated attention-deficit/hyperactivity disorder drug, Quillivant XR, to children.

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GSK aims to slash carbon emissions with next-generation inhaler

Fierce Pharma

Joining drugmakers like AstraZeneca and Novo Nordisk, GSK is making big strides in its quest to clean up its carbon footprint. | GSK plans to start late-stage trials of a low-carbon version of its metered dose inhaler (MDI) Ventolin utilizing a next-generation propellant in 2024. If the new product proves successful, it has the potential to slash greenhouse gas emissions from Ventolin use by roughly 90%.

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Poor Environmental Quality Associated With Higher Rates of Breast Cancer

Drug Topics

In counties with poor land quality, particularly urban counties, there was a higher incidence of early-stage disease and total breast cancer.

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Publix names new executive chairman, CEO and president

Drug Store News

Effective Jan. 1, CEO Todd Jones will become executive chairman, President Kevin Murphy will be promoted to CEO and Senior Vice President John Goff will be promoted to president.

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Wound care manufacturer controversy calls attention to shady dealings

Fierce Healthcare

Legacy Medical Consultants, a wound care manufacturer, is under fire for its business practices that critics say are another example of companies in the industry exploiting the Medicare system. | An independent investigation has shed light on one wound care manufacturer's rebate scheme that puts the onus on providers to report payments correctly.

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Bayer's trial flop, courtroom setback could restrict CEO's options amid strategic review: analyst

Fierce Pharma

After suffering setbacks in the clinic and in court over the last week, Bayer’s ability to overhaul its corporate structure is becoming more constricted, one group of analysts contends. | After suffering setbacks in the clinic and in court this week, Bayer’s ability to overhaul its corporate structure is becoming more constricted, one group of analysts contends.

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Why Medicare Advantage is lacking on cancer care

Fierce Healthcare

A City of Hope analysis found that Medicare Advantage members faced a delay of two weeks or more between diagnosis and their first course of therapy.

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Immunometabolism: Providing a new era of targeted medicine

pharmaphorum

In a new episode of the pharmaphorum podcast, web editor Nicole Raleigh speaks with Neil Weir, CEO of Sitryx Therapeutics, a smaller biotech that specialises in immunometabolism – a rapidly emerging and exciting area of investigation into the role of intracellular metabolic pathways in immune cells.

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STAT+: Mixed study results for MorphoSys blood-cancer drug raise questions about approval

STAT

LONDON — An experimental blood cancer drug from MorphoSys hit its primary target in a pivotal trial, the company announced late Monday, but the drug faltered in addressing patient symptoms, causing the company’s stock to fall in early Tuesday trading. In the Phase 3 trial, the German company was testing its drug candidate pelabresib combined with the drug Jakafi against a Jakafi-placebo duo in patients with newly diagnosed myelofibrosis, a type of rare blood cancer.

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GSK propels its progress to Net Zero

European Pharmaceutical Review

Phase III trials of a low carbon version of GSK’s metered dose inhaler, Ventolin (salbutamol), using a next generation, lower carbon propellant, are set to start in 2024. The pharma company stated that if successful, it has the potential to reduce greenhouse gas emissions from use of the inhaler by approximately 90 percent. According to GSK, thirty-five million patients with respiratory conditions globally relying on its metered dose inhaler.

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Pharmacists Can Educate Patients About Smoking Cessation Technology Options

Pharmacy Times

Free apps can help patients track cravings, monitor triggers, and stay motivated

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Lost in the mix of Medicaid 'unwinding': Kentucky cut off her healthcare over a clerical error

Fierce Healthcare

The day her Medicaid coverage ended, Beverly Likens was in the hospital after a scary trip to the emergency room. | Millions of people nationwide have lost Medicaid benefits after a pandemic-era mandate for coverage expired in March—most of them for administrative reasons unrelated to their actual eligibility.

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STAT+: Flagship Pioneering launches Quotient, a new biotech, in two countries

STAT

Flagship Pioneering, the venture capital firm behind Moderna, on Tuesday unveiled a new biotech called Quotient Therapeutics that will have offices in Massachusetts and the United Kingdom. Quotient, which was founded last year and had operated in stealth mode, wants to develop drugs that target illnesses caused by genetic changes that occur as people age.

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Watch DSN: GNC Health ventures into virtual health care

Drug Store News

Allison Bentley, senior director of strategic programs at GNC Health, shares why now is the right time for the global wellness brand to expand into digitized health care.

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STAT+: Pharmalittle: Texas sues Pfizer over ADHD drugs; Merck buys a neuro startup

STAT

Hello, everyone. Damian Garde here, filling in for Ed Silverman on what is an abbreviated work week here in the U.S., where the holiday discourse has pivoted from how to deal with quarrelsome relatives to whether a certain overexposed obesity treatment is ruining the apparently hallowed tradition of consuming more food than you need. If your personal geography spares you from all this, perhaps consider giving some thanks.

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BRUKINSA® granted significant EU approval in follicular lymphoma

European Pharmaceutical Review

BRUKINSA ® (zanubrutinib) in combination with the anti-CD20 monoclonal antibody obinutuzumab, has been approved by the European Commission (EC) to treat relapsed or refractory follicular lymphoma in individuals who have received at least two prior lines of systemic therapy. The oral treatment is now “the first Bruton’s tyrosine kinase (BTK) inhibitor approved in this indication and has the broadest label of any medicine in its class globally,” stated Dr Mehrdad Mobasher, Chief Medical Officer, H

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Experts Believe Gene Therapy Offers Potential to Impact Gaucher Disease Market

Pharmaceutical Technology

According to several key opinion leaders (KOLs) interviewed by GlobalData, pipeline gene therapy holds the greatest potential to transform the Gaucher disease landscape

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Expert: Working Together, Sharing Information Is Crucial to PBM Reform

Pharmacy Times

Cheryl Larson, president and CEO of the Midwest Business Group on Health, discussed the employers’ perspectives on pharmacy benefit manager (PBM) reform efforts and how they can dovetail with the concerns of pharmacies.

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More focus on precision medicine than ever before and what makes iSpecimen different

Outsourcing Pharma

OSP had a discussion with Tracy Curley, CEO of iSpecimen, and Eric Langlois, chief revenue officer of iSpecimen and Michael Howell,founder of Mountaineer Biosciences, Inc. to discuss a number of issues those working in precision medicine still face.

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Bayer’s new CEO was dealt a duo of ‘clearing events.’ Tough choices lie ahead

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, everyone. Damian here with a look at an ambitious genomics startup, some cautious optimism on Wall Street, and a rough day for an American in Germany.