Mon.Aug 28, 2023

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Cannabis Effective at Reducing Symptoms in Children With Cancer, but More Research Needed

Drug Topics

A recent systematic review found no serious adverse events related to the use of cannabis for the management of cancer-related symptoms in children.

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Transforming Medication Safety into a Value-Driver

Pharmacy Times

Advanced technology can automate many pharmacovigilance tasks to build workflow efficiencies, reduce manual intervention, and free up team members for more strategic activities.

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Evaluating Pharmacist-Driven CGM Services in Community, Ambulatory Care Settings

Drug Topics

A recent study found that there was a lack of strong evidence supporting the use of continuous glucose monitor programs in community pharmacies.

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Study: Non-O Blood Type Transfusions, Higher Intravenous Immunoglobulin Lead to Increased Risk of Hemolytic Reactions

Pharmacy Times

Although the patient demographics are similar for the 3 categories of hemolytic reactions with intravenous immunoglobulin, the reaction with delayed hemolytic transfusion reactions was highest compared to the other 2 hemolytic reactions.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Better Neighborhood Conditions Associated With Lower Asthma Rates in Children

Drug Topics

Researchers believe a recent study shows how living in neighborhoods with high and very high levels of opportunity in early life is associated with lower asthma incidence in childhood.

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The Growth of Biosimilars Continues to Create Hope for Lower Drug Costs

Pharmacy Times

Perhaps the most significant development in the pharmaceutical industry in decades, crops of biosimilars are being approved and are ready for distribution. What lies next, in terms of legislation and the impact on pharmacists, remains to be seen.

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Keeping Empathy Alive in the Health Care Industry With Help From AI

Pharmacy Times

With the help of new and complex algorithms and self-learning models, we are currently privy to what we may look back on as the golden era of AI.

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Meet the exec aiming to improve consumer experience for BCBSMA members

Fierce Healthcare

Blue Cross Blue Shield of Massachusetts announced< | Blue Cross Blue Shield of Massachusetts tapped Paul Long to serve as the health plan’s chief consumer experience officer.

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Researchers Announce Positive Results from Phase 2 At-Home Ketamine Trial

Pharmacy Times

KET01 could successfully treat treatment-resistant depression while limiting adverse effects in the home environment, according to the study.

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Rite Aid reportedly plans bankruptcy filing to restructure debt, halt pending opioid lawsuits

Fierce Healthcare

Rite Aid is reportedly preparing to file for bankruptcy within a few weeks to help restructure its debt and potentially halt ongoing lawsuits. | The bankruptcy would reportedly pause the many legal claims against the retailer and allow it to consolidate and resolve them in one place.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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The Evolving role of the Pharmacist in Addressing the Opioid Epidemic

Pharmacy Times

Pharmacists' expertise is invaluable to prescribers who are unfamiliar with opioid use disorder treatment protocols.

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After Catalent rumors, Danaher strikes $5.7B deal to acquire antibody specialist Abcam

Fierce Pharma

It’s a sale. Two months after Abcam launched a strategic review of the company, the British antibody research expert has revealed that it’s being bought by Danaher. | Danaher Corporation is picking up all outstanding shares of Abcam for $24 apiece. Both companies’ boards unanimously approved the decision, Danaher and Abcam said Monday. The deal is expected to close in mid-2024.

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FDA Announces Delayed Enforcement of DSCSA to 2024

Pharmacy Times

The start date of the package-level electronic tracking system will shift from November 27, 2023 to November 27, 2024.

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AstraZeneca uses Farxiga's versatility to guide pipeline work, exec says

Fierce Pharma

With seven posters and nine presentations on Farxiga over the weekend at the European Society of Cardiology (ESC) scientific sessions in Amsterdam, AstraZeneca made it clear that it has lots to say | As AstraZeneca's Farxiga has added four indications over the last five years—on top of its initial 2014 approval for Type 2 diabetes—its spillover benefits have become apparent and yielded a better understanding of the interconnections between Type 2 diabetes, heart failure and chronic kidney d

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: Feds fine Medicare Advantage plans for overcharging their members

STAT

The federal government has started penalizing Medicare Advantage insurers that have one common, glaring problem: Faulty technology systems are leading to people paying more for care and coverage than they should be. The Centers for Medicare and Medicaid Services fined three different Medicare Advantage plans this month, each one getting dinged differently for the way they overcharged their members.

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Can you give cats Benadryl?

The Checkup by Singlecare

Benadryl , or diphenhydramine hydrochloride in its generic form, is an antihistamine commonly prescribed to treat allergy symptoms like a runny nose, sneezing, or itching. Additionally, brand-name Benadryl is an antiemetic, which means it can help reduce nausea and vomiting, and it can be used as a sleep aid or anti-anxiety medication (thanks to its side effect of drowsiness).

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What do new weight loss drugs mean for the future of bariatric surgery?

STAT

Over the past year, weight loss drugs have captured the public’s imagination but also raised existential questions about the future of bariatric surgery. For obesity, surgery has long been — and continues to be — the most effective treatment, reducing patients’ risk of sleep apnea, diabetes, cancer, cardiovascular disease, and death.

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L.A. Care invests $4M in street medicine to expand unhoused's access to care

Fierce Healthcare

L.A. Care Health Plan is investing $4.05 million in a street medicine initiative to expand access to care for unsheltered people. | Nine organizations offering street medicine services will each receive up to $500,000 from the health plan. The program aims to beef up street medicine teams serving LA, as well as to ensure people without stable housing do not drop off Medi-Cal amid Medicaid redeterminations.

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Opinion: Psychiatrists like us cannot keep up with their inboxes

STAT

When you’re a psychiatrist, there’s no such thing as a typical day. But if you’re working in a clinic setting (like one of us, Jessi, is currently, and the other, Simone, has done previously), one thing is for sure: You’re busy. And it’s not just about seeing patients — it’s the seemingly ever-increasing electronic messages.

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Bon Secours Mercy Health sues Anthem over $93M in alleged unpaid claims

Fierce Healthcare

Bon Secours Mercy Health took its ongoing spat with regional Elevance Health plans to the next level on Monday, filing suit against the insurer alleging that it owed more than $93 million in unpaid | Bon Secours Mercy Health took its ongoing spat with regional Elevance Health plans to the next level on Monday, filing suit against the insurer alleging that it owed more than $93 million in unpaid claims.

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After UAE expansion, Resilience plants production flag in Saudi Arabia

Fierce Pharma

Echoing an earlier move in the United Arab Emirates, CDMO National Resilience is again growing its presence in the Middle East. | CDMO National Resilience the latest drugmaker to set down roots in Saudi Arabia, following in the footsteps of Sanofi and Merck KGaA.

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'Tsunami of exclusion': Patients shut out while payers cut obesity drug coverage

Fierce Healthcare

As health plans drop costly GLP-1 drugs, controversially leaving people without access to potentially life-changing therapies, health companies are hoping to fill the marketplace void to provide be | Obesity impacts roughly 40% of Americans, but insurers are becoming less willing to cover weight loss drugs for the disease. Health companies are looking to bridge the gap.

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Listen: Housing is health care

STAT

Long Island is in the midst of a housing crisis. Just like in many other parts of the country, Long Islanders are having a tough time finding affordable housing — an issue that is intimately connected with health.  Earlier this year, New York Gov. Kathy Hochul put forth a plan to deal with the housing challenges. Her ambitious goal: to construct 800,000 new homes and apartment units throughout the state over the next decade.

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FTC pauses litigation, mulls settlement as industry rallies around Amgen's $28B Horizon deal

Fierce Pharma

After filing a closely watched lawsuit to block Amgen's proposed takeover of Horizon Therapeutics, the Federal Trade Commission (FTC) is pausing those efforts to consider whether it should settle t | The Federal Trade Commission has paused its challenge of the $27.8 billion merger between Amgen and Horizon Therapeutics to rethink whether it should settle the case.

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STAT+: FDA delays enforcement of a pharmaceutical supply chain law to stop counterfeit drugs

STAT

In response to growing complaints, the U.S. Food and Drug Administration has postponed its plans to enforce a law designed to thwart counterfeit or diverted medicines passing through the pharmaceutical supply chain. The law was supposed to be fully enforced in late November, but the agency now says it will not take action until November 2024. At issue is the Drug Supply Chain Security Act, which has been implemented in steps over the past decade.

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Novo Nordisk set to launch weight loss drugs in more countries but in constrained fashion, CEO says

Fierce Pharma

It’s been well documented how Novo Nordisk has had difficulty in meeting the soaring demand for its GLP-1 weight loss treatments. | Amid supply problems, Novo Nordisk plans to launch its GLP--1 drugs in “more and more” countries, CEO Lars Fruergaard Jørgensen said at a recent Reuters event, though he added that the launches will be "constrained.

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ProMED issues ultimatum to striking moderators, as questions about site’s future persist

STAT

Striking moderators of the infectious diseases surveillance website ProMED have been given an ultimatum: Signal their interest in remaining with the program by Wednesday and return to work on Friday, or they will be considered to have “moved on” from the organization. The moderators, subject matter experts who are paid a nominal stipend for curating and contextualizing the numerous infectious diseases reports ProMED posts to its website and pumps out to its mailing list daily, have

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Alnylam to appeal COVID-19 vaccine patent ruling in Moderna case

Fierce Pharma

As Alnylam persists in its COVID-19 patent litigation, the RNAi specialist has been dealt a blow in one of its lawsuits against Moderna. | As Alnylam persists in its COVID-19 patent litigation, the RNAi specialist has been dealt a blow in one of its lawsuits against Moderna. But Alnylam says it'll appeal the recent ruling.

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A broad genetic test saved one newborn’s life. Research suggests it could help millions of others

STAT

CINCINNATI — Brynn Schulte nearly died twice when she was a baby, at one point needing emergency surgery for massive bleeding in her brain. No one knew what was wrong until a test that looked at her full genetic blueprint found a rare bleeding disorder called factor XIII deficiency — an early diagnosis that saved her life.

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siRNA therapy shows long-term potential in lowering LDL-C

European Pharmaceutical Review

Novartis has announced that Leqvio ® (inclisiran) , the first and only small interfering RNA (siRNA) therapy indicated to reduce low-density lipoprotein cholesterol (LDL-C), has demonstrated promising long-term results. This is based on three-year follow up data from a Phase III trial, presented at the European Society of Cardiology (ESC) Congress 2023.

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Hospitals' operating margins fell in July as fewer patients sought care

Fierce Healthcare

Nationwide hospital finances hit a rough patch in July as reduced patient volumes, a bump in bad debt and charity care whittled operating margins. | Patient volumes, particularly in outpatient settings, saw a steep month-over-month decline while Medicaid redetermination appears to have sparked a bump in bad debt and charity care, per Kaufman Hall.

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Rite Aid reportedly preparing to file for bankruptcy

Drug Store News

Rite Aid is reportedly planning to file for bankruptcy to address federal and state lawsuits it is facing over its alleged role in the sale of opioids, per a WSJ report.

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Pfizer telegraphs 4th-quarter production restart at North Carolina plant damaged by tornado

Fierce Pharma

With many medicines from Pfizer’s Rocky Mount, North Carolina, production plant relegated to an emergency ordering list following a devastating tornado last month, hospitals and government health o | With many medicines from Pfizer’s Rocky Mount, North Carolina, production plant relegated to an emergency ordering list following a devastating tornado last month, hospitals are likely eager for the massive injectables facility to restart production.

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Novel Spray Technique Has Potential to Deposit Bioactive Materials With 100% Efficiency

Pharmacy Times

This technique may be applied to transdermal applications, such as shot-free vaccines.

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