Wed.Feb 21, 2024

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Stealing With Our Eyes Open

Drug Topics

How much longer can independent pharmacists survive with the current method of reimbursement?

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NIH study of ME/CFS points to immune dysfunction and brain abnormalities at core of long-dismissed disease

STAT

Alison Sbrana was in the belly of an opera when her life changed. Down in the pit, surrounded by fellow orchestra members, she’d been straining to play her flute for half the show. As performers overhead enveloped the audience in arias, Sbrana felt like the Hulk was pulling on the tendons in the right side of her neck. “I begged anybody for meds at intermission,” she said.

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Trending Sources

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Elranatamab-bcmm Approved for Adult Patients With Relapsed or Refractory Multiple Myeloma

Drug Topics

The novel drug elranatamab-bcmm (Elrexfio) received accelerated FDA approval on August 14, 2023, for treating adults with relapsed or refractory multiple myeloma.

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Meet the fetal surgeon forging CRISPR’s next frontier: curing diseases in the womb

STAT

SAN FRANCISCO — Outside, the August sun wasn’t yet visible through the thick folds of fog blanketing the San Francisco skyline. Its warmth did not reach the operating room tucked into the sprawling Parnassus Heights hospital complex. In there, the light was all cold and blue fluorescence washing over the sea of scrub caps huddled around an anesthetized young woman on a gurney.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Differentiate Your Pharmacy With Unique Product, Service Offerings

Drug Topics

Offering services such as point-of-care testing and bundled products marketed as recovery kits can increase customer loyalty.

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Small study adds to growing hope CAR-T cell therapy could revolutionize autoimmune disease treatment

STAT

People with autoimmune disorders don’t usually get to talk about a cure. There’s symptom management, hopeful periods of remission often followed by relapses, but rarely a lasting fix for the way their immune system attacks healthy cells. If the immune system is an army, then those with conditions like lupus, multiple sclerosis, or rheumatoid arthritis are often fighting a never-ending war of friendly fire.

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STAT+: Scientists take a (small) step toward universal antivenom

STAT

Antivenom, like Mexican Coke or grandma’s cookies, is still made the old-fashioned way. In antivenom’s case, the recipe is straightforward: Pump a horse full of sub-lethal doses of venom from various local snakes, wait for them to develop an immune response, tap their blood, purify out antibodies, bottle, and freeze. This vampiric, century-old process still reigns because of the unique scientific challenge posed by snake venoms.

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UnitedHealth, HAC study: How social health factors impact employer plans

Fierce Healthcare

Given the impact that social factors have on overall health, employers can better manage costs and outcomes by embracing deeper, population-level data analysis, according to a new white paper. | Given the impact that social factors have on overall health, employers can better manage costs and outcomes by embracing deeper, population-level data analysis, according to a new white paper.

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Opinion: How Medicare leaves Puerto Ricans behind

STAT

When I accompany my father to his regular cardiologist appointment in Puerto Rico, worry and sadness always come along with us. While treatment has kept his health stable, I am still troubled that he always has to ask his doctor for medication samples. If he lived in any of the 50 states, Medicare would have provided coverage for his medical needs. But because he lived in Puerto Rico, Medicare is far less useful to him.

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Novavax dodges COVID vaccine refund by settling Gavi arbitration for up to $400M

Fierce Pharma

On the heels of a turbulent 2023 in which Novavax’s very existence was at stake, the beleaguered vaccine maker has new reason to be optimistic about the future. | Novavax has reached a settlement with Gavi, the Vaccine Alliance ending arbitration tied to a 2021 advance purchase agreement around its prototype COVID-19 vaccine NVX-CoV2373. Had Novavax lost the arbitration, the company might have had to refund nearly $700 million.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Hospitals race to adopt generative AI, even as regulators struggle to keep up with the risks

STAT

Usually the words generative AI in health are followed by a bold claim. The technology will transform some aspect of care delivery, save gobs of money, or automate administrative tasks crucial to connecting patients with timely services. Rohit Chandra, chief digital officer of the Cleveland Clinic, said generative AI can accomplish all these things.

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Novo Nordisk, Eli Lilly lead industrywide sales surge in Q4

Fierce Pharma

In a year that started with more than two-thirds of biopharma companies posting | While Novo Nordisk and Eli Lilly continued to be the biopharma industry growth leaders in the fourth quarter of 2023, many other drugmakers also delivered big gains, including Daiichi Sankyo, Amgen, Teva, GSK and Novartis.

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The evolution of clinical research: embracing new delivery models in the UK

pharmaphorum

Explore the evolution of clinical research in the UK, including the role of NIHR and Direct Delivery Teams in embracing new delivery models. Join our informative webinar to learn more.

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Emerging Markets Offer Pharma Its Next Growth Opportunity

Pharmacy Times

National governments and global non-governmental organizations are trying to expand access to essential medicines and treatments in developing countries.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Novo, Novartis, BMS and J&J win judge's blessing to combine arguments in upcoming IRA hearing

Fierce Pharma

Four major drugmakers are joining forces as they prepare to battle certain aspects of the Inflation Reduction Act (IRA) in court next month. | A federal judge in New Jersey agreed to let Bristol Myers Squibb, Novo Nordisk, Novartis and J&J present oral arguments together in their bid to challenge the government's new Medicare negotiations framework.

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FDA Approves sBLA for Reduced Dosing Frequency of Teclistamab-cqyv for Patients With RRMM

Pharmacy Times

Teclistamab was previously approved in October 2022 for the treatment of adult patients with relapsed or refractory multiple myeloma who received at least 4 prior therapies.

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Long-Acting Injectable Cabenuva Found More Effective Than Daily ART at Suppressing HIV in Patients With Adherence Challenges

Pharmaceutical Commerce

Cabenuva (cabotegravir + rilpivirine) showed superior efficacy in maintaining viral load suppression in patients with HIV compared with standard of care daily oral antiretroviral treatment.

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The Gut Microbiome Looks Different for People With Treatment-Resistant Schizophrenia

Pharmacy Times

Investigators suggested that this difference is caused by a common medication for treatment-resistant schizophrenia.

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MA enrollees constrained by prior auth but docs more likely to ask about health assessments: report

Fierce Healthcare

Medicare Advantage (MA) beneficiaries are more likely than traditional Medicare enrollees to experience delays in care while they wait for prior authorization approval, but MA members are likely to | Medicare Advantage and traditional Medicare enrollees experience similar access to services and similar challenges, a report from the Commonwealth Fund concluded.

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Mobile ADHD awareness game launches in Germany

pharmaphorum

Attention-deficit hyperactivity disorder (ADHD) in adults is not well understood and highly underdiagnosed, but the developers of a mobile game designed to raise awareness hope to shine a light on the struggles of people struggling with the condition.

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Joseph Papa, after leaving Bausch, begins another turnaround project as CEO of Emergent BioSolutions

Fierce Pharma

Joseph Papa has reemerged nearly a year after stepping down as head honcho of Bausch + Lomb. | Joseph Papa has re-emerged nearly a year after stepping down as head honcho of Bausch + Lomb. The former Valeant helmsman is now tasked with turning around Emergent BioSolutions as its new CEO.

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STAT+: DarioHealth acquires Twill, hoping it’s a shortcut to profitability

STAT

DarioHealth, which makes apps for managing chronic diseases, today announced it will acquire digital mental health company Twill for $10 million in cash plus stock valued at over $20 million at the end of Tuesday trading. The move is a bet that a consolidated offering can attract a critical mass of large customers in a market where profits have been elusive.

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PhRMA, navigating turbulence, taps Gilead CEO to helm board of directors

Fierce Pharma

Following the exodus of several prominent drugmakers and some surprising drug pricing setbacks in Washington, the influential industry lobbying group PhRMA has been busy navigating new challen | PhRMA revealed that Gilead CEO Daniel O’Day has donned the mantle as chair of the board of directors, replacing Novartis chief Vas Narasimhan, who held the position for much of 2023.

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Is it safe to take omeprazole during pregnancy?

The Checkup by Singlecare

Pregnancy can be an exciting time, but it’s not without an unpleasant side effect or two. Up to half of pregnant women experience gastroesophageal reflux disease (GERD) , also known as indigestion or heartburn. There are many medications and natural remedies for acid reflux. Prilosec ( omeprazole ) is a commonly used over-the-counter (OTC) heartburn medication.

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Laura Geller Beauty ushers in new era on the heels of product milestone

Drug Store News

DSN spoke to Laura Geller about its "Let’s Face It” campaign, the 20th anniversary of the Baked Balance-n-Brighten Color Correcting Foundation and a new summer product launch.

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7 foods to avoid while taking pantoprazole

The Checkup by Singlecare

Pantoprazole, also known by the brand name Protonix, is used to prevent and treat stomach ulcers and gastroesophageal reflux disease (GERD). GERD is a medical condition that occurs when there is a backflow of stomach acidic content into the esophagus (also called acid reflux), causing heartburn, injury to the lining of the esophagus, and other gastrointestinal symptoms.

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What are consumers’ attitudes about OTCs?

Drug Store News

Recent data from YouGov Profiles reveals that nearly half of Americans (47%) buy OTC drugs as required rather than stocking up, followed by 39% who keep a stock of medications but buy others when necessary.

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Celebrating Thank a Resident Day 

Board Vitals - Pharmacist

Medical residents play an important role in healthcare, from providing patient care to conducting research and collaborating with healthcare teams. To honor residents and their contributions and sacrifices, we celebrate Thank a Resident Day—a day dedicated to expressing gratitude for these remarkable individuals. What is Thank a Resident Day? Medical residency is a demanding journey filled with long hours, challenging cases, and constant learning.

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Many disproportionate share hospitals face lower Medicaid payments under new final rule

Fierce Healthcare

Medicaid disproportionate share hospital (DSH) payments are being cut by $8 billion annually during the current and next four federal fiscal years under a new Centers for Medicare and Medicaid Serv | Published Tuesday and set to go into effect in two months, the final rule limits the calculation of a hospitals Medicaid shortfall to beneficiaries with Medicaid as their primary payer.

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US, EU regulators start swift reviews of Servier glioma drug

pharmaphorum

FDA and EMA start speedy reviews of Servier’s vorasidenib for IDH-mutated low-grade glioma, hoping to end decades of stagnation in therapies for the brain cancer.

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Aetna Better Health of Illinois continues to address health disparities

Drug Store News

Aetna Better Health of Illinois is hosting Community Health Councils and introducing new benefits to eliminate barriers to achieving better physical and mental health.

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United sues FDA to try to block rival’s drug application

pharmaphorum

United sues FDA for allowing a marketing application for a competitor to its top-seller Tyvaso, filed by Liquidia, that sidesteps established procedures

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Watch: What is in utero gene editing?

STAT

Recently approved gene therapies offer patients one-time, potentially curative treatments for genetic diseases such as sickle cell anemia and beta thalassemia. But “one-time” miracle solutions can often be multi-month affairs, require millions of dollars, and cause painful side effects. What if that doesn’t have to be the case? In utero gene editing , or prenatal somatic cell genome editing, envisions treating a fetus diagnosed with a genetic disease before birth, thereby pr

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An Interview with Dr. Daled Serrano-Bahri

Drug Topics

Dr. Daled Serrano-Bahri, PharmD, is the associate director of MSL Training, and Inflammation & Autoimmunity at Incyte.

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