Fri.Feb 16, 2024

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FDA Approves Omalizumab to Reduce Food-Based Allergic Reactions in Adult and Pediatric Patients

Pharmacy Times

This marks omalizumab’s fourth FDA-approved indication for allergic and inflammatory conditions, such as severe persistent allergic asthma, with its initial approval being in 2003.

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STAT+: In ‘major milestone,’ FDA approves first cell therapy for solid tumors

STAT

Nearly four decades after its first conception, the first TIL therapy, an immunotherapy that harvests cancer-fighting immune cells from the patient’s own body, received accelerated approval from the Food and Drug Administration for advanced melanoma. The therapy, called Amtagvi or lifileucel from Iovance, is the first cell therapy approved for a solid tumor.

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FDA approves Iovance’s Amtagvi as first T-cell therapy for a solid tumor

Fierce Pharma

The T-cell therapy treatment class, which has transformed the treatment of certain blood cancers, has now reached the solid tumor field thanks to an FDA approval for a first-of-its-kind immunothera | The T-cell therapy treatment class, which has transformed the treatment of certain blood cancers, has now reached the solid tumor field thanks to an FDA approval for a first-of-its-kind immunotherapy developed by Iovance Biotherapeutics.

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STAT+: For unlucky mountaineers, tundra explorers and the unhoused, a new drug could avert the ravages of frostbite

STAT

Two days after his right hand froze, Hart Bezner realized for the first time that he might lose it.  The retired physics professor was sitting in an emergency room in Whitehorse, the capital of Canada’s Yukon territory, where two doctors and a pharmacist were taking an unusual amount of interest in the appendage and the pink blisters that now covered it.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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FDA approves Roche, Novartis' Xolair to prevent severe outcomes from common food allergies

Fierce Pharma

People with food allergies finally have a drug that can help prevent severe outcomes—and it’s a drug that’s been on the market for two decades. | People with food allergies finally have a drug that can help prevent severe outcomes—and it’s a drug that’s been on the market for two decades. The FDA has blessed Roche and Novartis’ Xolair as the first medicine to reduce allergic reactions that can occur with accidental exposure to certain foods.

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Solving astronauts’ health challenges in deep space could have payoffs on Earth

STAT

Space is famously known as the final frontier for human exploration. It may also be the final frontier for human medicine. That’s what Dorit Donoviel, executive director of the Translational Research Institute for Space Health, and her team are working towards. TRISH is a consortium between Baylor College of Medicine, Caltech, and the Massachusetts Institute of Technology that partners with NASA to solve the health challenges of humans exploring deep space.

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Pharmacists Can Help to Optimize the Total Health of Patients with Heart Conditions

Pharmacy Times

Pharmacists can host community events and try different marketing efforts to drive community awareness about heart health and total health.

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'New set of digital table stakes': Most executives see tech as worthy investment, EY survey finds

Fierce Healthcare

Nearly all healthcare executives believe new digital health technologies are worth the cost, even though they have yet to see a financial return from it, a new survey reveals. | Nearly all healthcare executives believe technology is worth the cost, even though they have yet to see a financial return from it, according to a new survey from EY. Most believe in its power to reduce costs and boost provider credibility.

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STAT+: Medicare Advantage enrollment races past 33 million

STAT

Roughly 33.4 million adults older than 65 and people with disabilities were enrolled in a Medicare Advantage plan as the calendar flipped to 2024 — another year of steady, albeit slower, growth for the taxpayer-funded program. Enrollment increased 7.1% year over year, which would make this year’s annual growth rate identical to last year’s , according to new federal Medicare Advantage enrollment data analyzed by STAT.

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J&J consumer health spinoff Kenvue telegraphs 100-plus layoffs in California, New Jersey

Fierce Pharma

While Johnson & Johnson’s consumer health spinoff Kenvue prepares to move into a swanky new headquarters in Summit, New Jersey, it appears some staffers won’t be joining the company in the tran | While Johnson & Johnson’s consumer health spinoff Kenvue prepares to move into a new headquarters in Summit, New Jersey, it appears some staffers won’t be joining the company in the transition.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Leading MD Anderson oncologist disputes junior scientist’s claims in lawsuit over research credit

STAT

Prominent immunologist and oncologist Padmanee Sharma defended herself in court on Friday against a lawsuit that alleges she threatened to undermine a junior faculty member’s career, made defamatory comments about the younger scientist, and attempted to take credit for work that she didn’t do. In legal filings submitted to the Harris County District Court, Sharma said that she made substantial contributions to an immunotherapy project that were ignored, and that a third-party asses

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Novartis, zeroing in on innovative meds, launches strategic review of India outfit

Fierce Pharma

A Novartis subsidiary in India has become the target of a strategic review as the Swiss pharma focuses its efforts on newer medicines. | A Novartis subsidiary handling old products in India has become the target of a strategic review as the Swiss pharma focuses its efforts on newer medicines.

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Study backs safety of Gilead CAR-T as outpatient therapy

pharmaphorum

CAR-T therapies can achieve remarkable efficacy in the treatment of haematological cancers, but the risk of side effects means that the cell infusions are almost always administered to inpatients under close supervision in clinics.

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Replacing Salt With Substitute May Lower Hypertension Risk in Older Adults

Drug Topics

Study results indicate that using salt substitutes can be a viable population-wide strategy in preventing cardiovascular disease and controlling hypertension.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Freenome raises $254m for cancer tests, and other financings

pharmaphorum

Recent biotech financings include a $245m raise for cancer blood test company Freenome, plus big rounds for Cogent Biosciences, BioAge Labs, Latigo Biotherapeutics, ProfoundBio, and Firefly Bio

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Half of shoppers would break up with a business over incorrect online details, study finds

Drug Store News

SOCi's Consumer Behavior Index shows consumers have little patience for online inaccuracies, including incorrect store hours, website information, contact details and more.

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Medication abortions over telehealth effective and safe, researchers share ahead of major SCOTUS case

Fierce Healthcare

The effectiveness and safety of medication abortions obtained via telehealth are on par with those delivered in person, with no differences in outcomes between synchronous and asynchronous communic | Both synchronous and asynchronous approaches to medication abortion led to outcomes on par with in-person prescribing, a finding that addresses one of the key issues SCOTUS is scheduled to consider next month.

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More people die after smoking drugs than injecting them, study finds

STAT

NEW YORK — Smoking has surpassed injecting as the most common way of taking drugs in U.S. overdose deaths, a new government study suggests. The Centers for Disease Control and Prevention called its study published Thursday the largest to look at how Americans took the drugs that killed them.

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Industry can support clinicians with prescribing decisions

pharmaphorum

The ABPI has released a new guide on how the industry can support clinicians with prescribing decisions. Find out more about how pharmaceutical companies can assist healthcare professionals in providing optimal patient care.

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Following FDA rejection, Sanofi and Regeneron's Dupixent gains Japanese approval in hives condition

Fierce Pharma

Four months after the FDA rejected Sanofi and Regeneron’s Dupixent to treat chr | Four months after the FDA rejected Sanofi and Regeneron’s Dupixent to treat chronic spontaneous urticaria, Japan’s health regulators have signed off on the drug in the indication.

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Pharmacy Technicians Play Key Role in Avoiding Medication Errors

Pharmacy Times

Taking a few seconds to double-check a prescription can have significant impacts on patient safety

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STAT+: Flagship Pioneering startup lays off a third of staff

STAT

Sonata Therapeutics, a startup created two years ago through the merger of two Flagship Pioneering companies, has laid off about a third of its staff. The biotech laid off 21 employees in recent weeks, according to employee posts on social media and a company spokesperson. Sonata had around 63 employees before the layoffs. Sonata is just the latest in a series of startups laying off employees in order to stretch out their cash runways.

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Gilead’s CD47 woes continue, this time in solid tumours

pharmaphorum

Gilead Sciences has paused enrolment in clinical trials of its CD47 drug magrolimab in solid tumours, a week after dropping it for blood cancers.

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Study: Chronic worker shortages in nursing homes must be addressed to help lessen patient risk

Fierce Healthcare

The now chronic problem of more expensive agency staff and potentially lower quality care in nursing homes needs to be addressed as part of calls for increased oversight of the sector, according to | The now chronic problem of more expensive agency staff and potentially lower quality care in nursing homes needs to be addressed as part of calls for increased oversight of the sector, according to a recent academic study in Health Affairs.

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Astellas pledges $800m to Kelonia CAR-T alliance in cancer

pharmaphorum

Astellas has signed a deal with Kelonia Therapeutics that aims to push the boundaries of what can be achieved with CAR-T therapies in immuno-oncology

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Research Examines Disparities in Mental Health Care for Some Gender Identities

Pharmacy Times

One significant difference was an increased rate of bupropion prescriptions for transgender females.

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Patentability and predictability in AI-assisted drug discovery

pharmaphorum

Explore the role of artificial intelligence and machine learning in drug discovery and the challenges associated with patentability and predictability. Learn how AI is revolutionising the pharmaceutical industry.

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STAT+: Louisiana, Oregon deals show health insurer acquisitions aren’t a sure thing anymore

STAT

A deal is never really done until it’s done. On Tuesday, two different proposed insurance plan acquisitions on different sides of the country called it quits — one of them for the second time. California-based Medicare Advantage insurer SCAN Group has been trying to buy CareOregon, an insurer offering coverage to half a million people in Oregon’s state health plan, since January 2023.

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JP Morgan 2024 – Xavier Duportet

pharmaphorum

In this interview, Jonah Comstock speaks with Xavier Duportet, the founder and CEO of the biotech company, Eligo Bioscience, about the future of CRISPR gene editing at JP Morgan in 2024. Dive into the discussion to gain insights into this cutting-edge technology and its potential impact on the healthcare industry.

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Common heart health drugs now available under $30 through GoodRx

Fierce Healthcare

GoodRx is offering 30 common heart health medications for less than $30 at more than 70,000 pharmacies across the country. | Cardiovascular disease is the leading cause of death in the U.S. Thirty common generic and brand medications for heart health are now available across more than 70,000 U.S. pharmacies through GoodRx.

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STAT+: Bipartisan group of lawmakers warns of a rising Chinese threat to U.S. biotech

STAT

CAMBRIDGE, Mass. — The increasingly adversarial relationship between the United States and China has raised national security concerns about Chinese penetration into key sectors of the U.S. economy, such as technology, manufacturing, and clean energy. Now, some in Congress are raising alarms about China’s threat to another vital industry: biotechnology.

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Patterns of behaviour: Using AI-based algorithms to improve outcomes for patients with atrial fibrillation

pharmaphorum

Patterns of behaviour: Using AI-based algorithms to improve outcomes for patients with atrial fibrillation Mike.

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STAT+: Pharmalittle: We’re reading about kids taking Wegovy, telehealth for abortion pills, and more

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is still shaping up, but we expect to promenade with the official mascots, check in on the Pharmalot ancestors, and hold another listening party, where the rotation will likely include this , this , this , this and this.

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Cosset, PurelifeBiotics awarded Buyers’ Choice Awards

Drug Store News

Cosset Bath & Body won the Drug Store News Buyers’ Choice Award for its Therapy Bombs and PurelifeBiotics was a finalist for its Shower Steamers.

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