Thu.Feb 01, 2024

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2-Dose HPV Vaccine Postpartum Equally Effective as 3-Dose

Drug Topics

Approximately 330,000 cases of precancerous cervical dysplasia and 12,000 cases of cervical cancer in the United States per year are attributed to HPV.

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Navigating Life’s Challenges: A Pharmacist’s Transformative Journey of Dedication and Compassion

Pharmacy Is Right For Me

Adversities and life’s trials often serve as catalysts that guide individuals toward their destined paths, unveiling unforeseen opportunities. Such is the transformative journey of Dr. Jorie Kreitman, a dedicated pharmacy manager at Walgreens. Early Inspiration Dr. Kreitman’s passion for pharmacy ignited at the tender age of 7 when she was diagnosed with Supraventricular Tachycardia (SVT), a condition characterized by irregularly fast or erratic heartbeats.

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Researchers Highlight Need for Greater Research Into RSV Among Older Adults, Vaccine Management

Pharmacy Times

The burden of RSV in the older population is becoming highly recognized as studies have assessed higher-risk individuals in industrialized and developing countries.

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Updated Covid vaccine has 54% effectiveness, new data suggest

STAT

New data released Thursday by the Centers for Disease Control and Prevention suggest that the most recent Covid-19 booster offers about 54% percent protection against infection with the virus. A study published in the CDC’s online journal Morbidity and Mortality Weekly Report showed that the updated vaccine was essentially equally effective at protecting against the strain targeted by the vaccine — called XBB.1.5 — and the JN.1 subvariant, which emerged after the vaccin

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Study: Hydroxyurea Reduces Severe, Invasive Infections by 60% in Children with Sickle Cell Disease

Pharmacy Times

The findings suggest that further research on additional intervention methods and expanding access to hydroxyurea in Africa could benefit young patients with sickle cell disease.

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Opinion: Why I left the editorial board of the prestigious scientific journal NeuroImage — and helped start something new

STAT

Last spring, I joined a rebellion. The entire editorial board of the prestigious scientific journal NeuroImage, of which I was a member, resigned after its publisher refused to take steps to ease the high costs scientists are required to pay for publication in the journal. While this decision threw the brain imaging research community into a frenzy, the rest of the world barely noticed.

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Clues from mice could help explain why women face a higher risk of autoimmune disorders

STAT

Researchers have long known that women are more likely to develop autoimmune disorders than men, though they’ve struggled to fully understand why. Now a new study in mice suggests a key part of the answer may be that an RNA molecule that’s indispensable for female survival steers the body toward immune friendly fire. A team led by Stanford scientists found that Xist, a molecule that teams up with proteins to keep female cells from activating a double (and deadly) dose of X chromoso

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Understand the Differences in Carbidopa/Levodopa Formulations for Parkinson Disease

Pharmacy Times

Understanding differences in the various levodopa formulations and assisting with medication therapy management is a crucial role for pharmacists.

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Opinion: Where do we go from here on digital therapeutics?

STAT

South Korea is the only country to officially recognize digital therapeutics as a category. Nevertheless, the concept of software-based tools designed to manage or treat medical conditions has received enormous attention in the U.S. as proponents tout their potential to both widen access to care and improve patient outcomes. This optimism has driven significant financial investment in the sector, which ballooned to $3.4 billion in 2021.

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FDA Grants Orphan Drug Designation to ‘1104, First-In-Class Peptide for Eosinophilic Esophagitis

Pharmacy Times

The designation offers support in developing potential new medicines, treatment, and diagnosis to prevent rare conditions, like EoE.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Hospital-backed proposal would make insurers reveal prior auth denial rates

Fierce Healthcare

A recommendation on the 2024 Measures Under Consideration list, brought forward by the Federation of American Hospitals (FAH), would add a quality measure in the Medicare Advantage (MA) star rating | The Federation of American Hospitals is pushing CMS for the inclusion of a star ratings quality measure that shows how often insurers overturn or uphold prior authorization denials.

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Strategies for Positive Change in Opioid Prescribing

Pharmacy Times

A panel of experts share insights on overcoming challenges in responsible opioid prescribing and explore emotional responses, aversion to change, and the role of interdisciplinary collaboration in addressing the opioid crisis.

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BIPOC Experience More Negative Effects After COVID-19 Infection

Drug Topics

A new study found that Hispanic patients were more likely to report fair or poor health and reduced activity compared to non-Hispanic patients at 3 months.

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STAT+: Can gene therapies make for a profitable business? Keep your eye on Bluebird Bio

STAT

Happy Groundhog Day eve. Some takes and thoughts on Bluebird Bio’s quest for gene therapy profits, a reality check on Vertex’s highly touted pain drug, and more ADC investor FOMO. Bluebird and the case for gene therapy profits Genetic treatments that are potential cures for inherited diseases are a huge medical advance, but can these transformational (and expensive) products become a profitable business?

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Who's No. 1? With $25B in sales, Merck's Keytruda looks to be the top-selling drug of 2023

Fierce Pharma

With Merck reporting a whopping $25 billion sales haul for | With Merck reporting a whopping $25 billion sales haul for Keytruda on Thursday, the PD-1 cancer superstar appears to be the world’s top-selling drug in 2023. Keytruda looks set to take over the top spot from Pfizer and BioNTech’s Comirnaty, which ruled the previous two years, scoring sales of $55.9 billion in 2022 and $55.1 billion in 2021.

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STAT+: General Catalyst wants to take over a safety-net health system in Akron. The city has questions

STAT

General Catalysts’s grand vision for a venture capital-owned hospital system seamlessly blending AI and tech into everyday appointments and rewarding staff for keeping patients healthy might sound alluring. But the firm’s bold experiment is facing hurdles even before it has started as the community served by the health system it hopes to buy is pushing back.

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The Pharmacist Can Assist Patients With Diabetes To Manage A New Lifestyle

Pharmacy Times

A growing number of adult and pediatric patients are being diagnosed with type 2 diabetes, despite increases in care modalities.

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STAT+: Biden administration makes opening offers in Medicare drug price negotiations

STAT

WASHINGTON  — The Biden administration is making its opening offers to pharmaceutical companies in its brand-new Medicare drug price negotiation program on Thursday, administration officials said. And that’s about all they said. The offers will not be made public unless a manufacturer chooses to publicly disclose information about the talks, a senior administration official said.

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At inaugural food-as-medicine summit, HHS announces partnerships to bolster the movement

Fierce Healthcare

The U.S. Department of Health & Human Services (HHS) announced new private-public partnerships to support the food as medicine movement at its first-ever summit on the topic on Wednesday. | HHS will be teaming up with Instacart, a grocery delivery company and two nonprofits, the Rockefeller Foundation and Feeding America. They will share research, communication and program implementations to advance the collective understanding of food as medicine.

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Novavax is on thin ice, and the latest update isn’t exactly encouraging

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up to get our biotech newsletter in your inbox. Hello, everyone. Damian here with the latest twist in biotech’s recovery, a close look at Bluebird Bio, and the uncertain future of a Covid-19 player. The need-to-know this morning Merck   reported  earnings for the fourth-quarter and 2023.

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Tenet Healthcare shares M&A updates, projects above-guidance 2023 earnings

Fierce Healthcare

Tenet Healthcare has disclosed a pair of new and completed hospital transactions alongside projections that next week’s 2023 financial report “will be above the high end” of its guidance. | The for-profit disclosed a new $1 billion deal to sell four California hospitals to UCI Health and said it has wrapped a previously announced $2.4 billion sale of three South Carolina hospitals to Novant Health.

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Sanofi expects RSV antibody to ?breach blockbuster status in 2024, even as supply hitch drags on

Fierce Pharma

As Sanofi strives to become a global immunology leader, it's also busy making the most of a crucial respiratory launch with partner AstraZeneca. | As Sanofi strives to become a global immunology leader, it's also busy making the most of a crucial respiratory launch with partner AstraZeneca. On both fronts, Sanofi expects to see dividends in 2024.

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Making connections and getting noticed as a biotech start-up

pharmaphorum

On today's podcast, brought to you by Kadans Science Partners, host Jonah Comstock is joined by Bradley Hardiman, Astellas Pharma’s Senior Director of Business Development; Mike Murray, head of Murray International Partners Ltd; and Mairi Dillon, Kadans' Ecosystem Manager for UK & Ireland.

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Merck still in the market for deals in the $1B to $15B range, CEO says

Fierce Pharma

Even after the acquisitions of Prometheus and Acceleron, Merck is ready to make more deals in the $1 to $15 billion range, according to CEO Rob Davis.

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Healthcare sector cybersecurity retrospective and the year ahead

pharmaphorum

As cyberattacks continue to target the healthcare sector, it is crucial to look back at cybersecurity incidents from the past year and prepare for the challenges that lie ahead. This retrospective discusses the impact on patients, health systems, insurers, and vendors, and highlights the importance of cybersecurity measures in protecting sensitive healthcare information.

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GSK inks another Zantac settlement ahead of trial in California

Fierce Pharma

After GSK spent the latter half of 2023 warding off concerns about the swelling Zantac product liability litigation, the company is back at the settlement table in 2024. | After GSK spent the latter half of 2023 warding off concerns about the swelling Zantac product liability litigation, the company is back at the settlement table in 2024.

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In-person, hybrid, or digital? State of pharma meetings and events in 2024

pharmaphorum

Explore the current state of pharmaceutical meetings and events in 2024, including the shift from in-person to virtual and hybrid formats. Discover how the industry is embracing diversity, equity, and inclusion in these gatherings.

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In Medicare negotiation process, HHS sends 1st price offers as industry blasts lack of transparency

Fierce Pharma

Despite litigation and denouncements from the biopharma industry, Medicare price negotiations under the Inflation Reduction Act are rolling on. | Despite litigation and denouncements from the biopharma industry, Medicare price negotiations under the Inflation Reduction Act are rolling on. And today, the government is sending out its first round of offers on affected drugs.

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Lundbeck study knocks confidence in alpha-syn as CNS target

pharmaphorum

A phase 2 trial of Lundbeck’s alpha-synuclein-targeting drug Lu AF82422 has failed to reach statistical significance in patients with multiple system atrophy (MSA), although the company says there are encouraging “signals of efficacy” in the data.

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Despite Roche's sharp COVID sales decline, eye drug Vabysmo powers major revenue win, CEO says

Fierce Pharma

As Roche CEO Thomas Schinecker sees it, the Swiss pharma made a “major achievement” in 2023. Despite a sharp decline in COVID-related sales, the company was able to grow overall revenues | As Roche CEO Thomas Schinecker sees it, the Swiss pharma made a “major achievement” in 2023. Despite a sharp decline in COVID-related sales, the company was able to grow overall revenues thanks in large part to the performance of eye disease drug Vabysmo.

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Walmart plans on adding more than 150 larger format stores

Drug Store News

Walmart plans to build or convert more than 150 larger-format stores during the next five years while also continuing its program to remodel existing locations.

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New Jersey's Atlantic Health System, Saint Peter's Healthcare System plan to merge

Fierce Healthcare

New Jersey providers Saint Peter’s Healthcare System and Atlantic Health System have taken the first step toward a merger they said would include “significant investments” in the Catholic system’s | The nonprofit systems promise new synergies and "significant investments" in the Catholic system's service area. The pair hope to hammer out a definitive agreement "within the coming months.

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STAT+: Raleigh-Durham challenges Boston as biomanufacturing hub of the future

STAT

MORRISVILLE, N.C. — Ten minutes from the Raleigh airport, the future of biotech is under construction. On either side of a new stretch of four-lane highway sit two $1 billion biomanufacturing campuses, which will bring a combined 2.5 million square feet of research and development and advanced manufacturing space to a region that has become the No. 1 place where North America makes prescription drugs.

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What to do if diabetes makes your feet swell

The Checkup by Singlecare

When someone is diagnosed with diabetes , they must keep a close eye on their blood sugar levels—but, surprisingly, they must also keep a close eye on their feet. People with diabetes are more prone to swelling in the lower legs and feet, a condition called lower extremity edema. Essentially, this is an excess buildup of fluid in the lower extremities.

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