Sat.Nov 04, 2023

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Various Cancer Types, Drugs May Cause Thrombotic Microangiopathy, Impact Kidney Health

Pharmacy Times

Leung discusses that various cancer types and drugs can cause thrombotic microangiopathy and impact kidney health and the renal complications connected to hematologic malignancies.

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STAT turns 8: A letter from the executive editor

STAT

Today STAT turns 8. In these annual letters, I usually talk proudly about all we have accomplished, from our singular coverage of the Covid pandemic to our years-in-the-making court victory to force Purdue Pharma to release documents about its OxyContin marketing efforts, to our success at becoming the go-to media outlet covering health and medicine.

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New Weight Loss Drugs May Have Cardiorenal Benefits for Patients with Kidney Disease

Pharmacy Times

Understanding the mechanisms leading to weight loss could help identify potential benefits for cardiorenal health in patients with chronic kidney disease.

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AMCP Poster Suggests Cutting Back GLP-1, DPP4 Duplicative Prescribing to Reduce Drug Spending

Drug Topics

A poster presented at AMCP Nexus 2023 outlined how a Pharmacy Therapeutics program yielded $7,500 in savings per patient and $3.5 million in savings overall by reducing patients' incretin therapy prescriptions from two to one.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Navigating Medication Challenges in Kidney Disease, Updating Prior Drug Dosing Consensus

Pharmacy Times

Awdishu describes the implementation of new equations to accurately drug dose in patients as well as provide updated guidance on the dosing of older medications.

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To Receive or Not to Receive, That is the Question with Patient Gifts

Board Vitals - Pharmacist

Ah, the holidays – the season of giving. It’s the time of year when patients want to express their gratitude for your care with gifts that may range from the ridiculous to the sublime. They are all given with good intentions, but should you accept them? And if you do, are all gifts created equal? Is a tin of cookies the same as a gift certificate or a day of golf?

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QL-325 by QLSF Biotherapeutics for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia): Likelihood of Approval

Pharmaceutical Technology

QL-325 is under clinical development by QLSF Biotherapeutics and currently in Phase I for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia).

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Common Medications for Diabetic Kidney Disease May Be Linked to Increased Risk of Hyperkalemia

Pharmacy Times

Sodium-glucose cotransporter-2 inhibitors and sodium zirconium cyclosilicate may be paired with these kidney disease medications to reduce high serum potassium.

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MBX-1416 by MBX Biosciences Inc for Hypoglycemia: Likelihood of Approval

Pharmaceutical Technology

MBX-1416 is under clinical development by MBX Biosciences Inc and currently in Phase II for Hypoglycemia.

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D3L-001 by D3 Bio for Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+ Breast Cancer): Likelihood of Approval

Pharmaceutical Technology

D3L-001 is under clinical development by D3 Bio and currently in Phase I for Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+ Breast Cancer).

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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D3L-001 by D3 Bio for Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+ Breast Cancer): Likelihood of Approval

Pharmaceutical Technology

D3L-001 is under clinical development by D3 Bio and currently in Phase I for Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+ Breast Cancer).

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Debio-4127 by Debiopharm International for Neuroendocrine Gastroenteropancreatic Tumors (GEP-NET): Likelihood of Approval

Pharmaceutical Technology

Debio-4127 is under clinical development by Debiopharm International and currently in Phase II for Neuroendocrine Gastroenteropancreatic Tumors (GEP-NET).

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Debio-4127 by Debiopharm International for Neuroendocrine Gastroenteropancreatic Tumors (GEP-NET): Likelihood of Approval

Pharmaceutical Technology

Debio-4127 is under clinical development by Debiopharm International and currently in Phase II for Neuroendocrine Gastroenteropancreatic Tumors (GEP-NET).

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QL-325 by QLSF Biotherapeutics for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia): Likelihood of Approval

Pharmaceutical Technology

QL-325 is under clinical development by QLSF Biotherapeutics and currently in Phase I for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia).

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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D3L-001 by D3 Bio for Gastroesophageal (GE) Junction Carcinomas: Likelihood of Approval

Pharmaceutical Technology

D3L-001 is under clinical development by D3 Bio and currently in Phase I for Gastroesophageal (GE) Junction Carcinomas.

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D3L-001 by D3 Bio for Gastroesophageal (GE) Junction Carcinomas: Likelihood of Approval

Pharmaceutical Technology

D3L-001 is under clinical development by D3 Bio and currently in Phase I for Gastroesophageal (GE) Junction Carcinomas.

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HUC-3443 by Huons for Idiopathic (Essential) Hypertension: Likelihood of Approval

Pharmaceutical Technology

HUC-3443 is under clinical development by Huons and currently in Phase II for Idiopathic (Essential) Hypertension.

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HUC-3443 by Huons for Idiopathic (Essential) Hypertension: Likelihood of Approval

Pharmaceutical Technology

HUC-3443 is under clinical development by Huons and currently in Phase II for Idiopathic (Essential) Hypertension.

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RPA-601 by Rocket Pharmaceuticals for Cardiomyopathy: Likelihood of Approval

Pharmaceutical Technology

RPA-601 is under clinical development by Rocket Pharmaceuticals and currently in Phase I for Cardiomyopathy.

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RPA-601 by Rocket Pharmaceuticals for Cardiomyopathy: Likelihood of Approval

Pharmaceutical Technology

RPA-601 is under clinical development by Rocket Pharmaceuticals and currently in Phase I for Cardiomyopathy.

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MBX-1416 by MBX Biosciences Inc for Hypoglycemia: Likelihood of Approval

Pharmaceutical Technology

MBX-1416 is under clinical development by MBX Biosciences Inc and currently in Phase II for Hypoglycemia.

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Melpida by Elpida Therapeutics for Paraplegia: Likelihood of Approval

Pharmaceutical Technology

Melpida is under clinical development by Elpida Therapeutics and currently in Phase II for Paraplegia.

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PHIN-214 by PharmaIN for Portal Hypertension: Likelihood of Approval

Pharmaceutical Technology

PHIN-214 is under clinical development by PharmaIN and currently in Phase I for Portal Hypertension.

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PHIN-214 by PharmaIN for Portal Hypertension: Likelihood of Approval

Pharmaceutical Technology

PHIN-214 is under clinical development by PharmaIN and currently in Phase I for Portal Hypertension.

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HUC-3443 by Huons for Hypercholesterolemia: Likelihood of Approval

Pharmaceutical Technology

HUC-3443 is under clinical development by Huons and currently in Phase II for Hypercholesterolemia.

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HUC-3443 by Huons for Hypercholesterolemia: Likelihood of Approval

Pharmaceutical Technology

HUC-3443 is under clinical development by Huons and currently in Phase II for Hypercholesterolemia.

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