Wed.Jun 21, 2023

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Insurance Coverage is Lagging in a Golden Age of Obesity Treatment

Drug Topics

Antiobesity medications are considered to be 'vanity drugs' by many private insurers, and the refusal to cover obesity treatment is counterproductive because of obesity's many health consequences.

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Common Antibiotics Associated with C. difficile Infection Include Piperacillin, Meropenem

Pharmacy Times

Antibiotics that were found to be most commonly associated with clostridium difficile infection are piperacillin/tazobactam, meropenem, vancomycin, ciprofloxacin, ceftriaxone, and levofloxacin, according to a recent study.

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Front-End Strategies for Consumer Convenience

Drug Topics

Beauty and household items topped the list of what customers want to buy in the pharmacy.

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CMS 2024 Final Rule Includes Surprises, Opportunities for Pharmacies and Payers

Pharmacy Times

Among health care professionals, pharmacists are best suited to serve as trusted partners for patients to help ensure they understand their medication regimen, identify medication-related problems, and work with prescribers to close gaps in care.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Xylazine, or ‘tranq,’ is making opioid overdoses harder to reverse

STAT

For years, public health guidance about opioid overdoses has been relatively simple: Administer naloxone , then call 911. But the days of simply spraying naloxone into an overdose victim’s nose, then watching that person resume breathing and wake up within minutes, are over.

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Breaking: CDC ACIP Recommends RSV Vaccination for Older Adults

Drug Topics

The first RSV vaccines were approved by the FDA earlier this year.

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STAT+: After promising early data, gene therapy trial for Huntington’s takes puzzling turn

STAT

Last year, after a string of high-profile trial failures , the Huntington’s disease community got positive news in the form of very early data from an experimental gene therapy for the rare neurodegenerative condition. On Wednesday, however, the company behind the drug released updated figures that were more mixed — even befuddling. The study from Uniqure, a Dutch biotech, randomized early stage Huntington’s patients to receive low-dose treatment, a high-dose treatment, or a

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Healthcare dealmaking 'resilient' despite regulatory, economic headwinds: PwC

Fierce Healthcare

Even in the face of substantial headwinds, dealmaking in the healthcare industry hasn't fallen off, according to a new analysis from PwC. | Even in the face of substantial headwinds, dealmaking in the healthcare industry hasn't fallen off, according to a new analysis from PwC.

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Novavax Protein-based Monovalent XBB COVID-19 Vaccine Ready for Fall Immunization Campaign

Pharmacy Times

Novavax announced the development of a protein-based monovalent XBB COVID-19 vaccine with the intention of it being manufactured and available for the fall vaccination campaign.

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Commonwealth Fund gives healthcare in southeastern states failing grades across the board

Fierce Healthcare

The southeastern region of the U.S. | The southeastern region of the U.S. scored worst across the board in the Commonwealth Fund’s annual scorecard on states' healthcare system performance.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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First adult anti-inflammatory cardiovascular drug approved

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved LODOCO ® , the “first drug to target cardiovascular inflammation,” reported Dr Paul Ridker, MPH, Professor of medicine at Harvard Medical School and Director of the Center for Cardiovascular Disease Prevention, Brigham and Women’s Hospital. It is the first anti-inflammatory cardiovascular treatment demonstrated to reduce the risk of myocardial infarction (MI), stroke, coronary revascularization, and cardiovascular death in adults with establ

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FDA Approves First SGLT2 Inhibitor for Use in Children With Type 2 Diabetes

Pharmacy Times

Jardiance and Synjardy approved as an addition to diet and exercise to improve blood sugar control in children aged 10 years and older with type 2 diabetes.

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Scientists successfully unfroze rat organs and transplanted them — a ‘historic’ step that could someday transform transplant medicine

STAT

The rat kidney was peculiarly beautiful — an edgeless viscera about the size of a quarter, gemstone-like and gleaming as if encased in pure glass. It owed its veneer to a frosty, minus 150-degree Celsius plunge into liquid nitrogen, a process known as vitrification, that shocked the kidney into an icy state of suspended animation. Then researchers at the University of Minnesota restarted the kidney’s biological clock, rewarming it before transplanting it back into a live rat ȁ

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First Anti-Inflammatory Drug for Cardiovascular Disease Approved by FDA

Drug Topics

Lodoco (colchicine) approval was based on a clinical trial with 5,522 patients with chronic coronary disease, which was published in Circulation in February 2022.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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PhRMA joins legal battle over Inflation Reduction Act's 'price-setting' measures

Fierce Pharma

After Merck and Bristol Myers Squibb took shots at the Inflation Reduction Act (IRA) in separate lawsuits, influential trade group Pharmaceutical Research and Manufacturers of America (PhRMA)—plus | Trade group PhRMA is the latest to go after the IRA in a lawsuit claiming violations of the Fifth and Eighth amendments. The suit follows similar legal efforts by Merck and Bristol Myers Squibb.

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‘I’m Not Crazy, I’m Sick’: A film dives deep into chronic Lyme disease

STAT

Elle Brooks-Tao, a filmmaker, got thrust into the confusing world of Lyme disease when a family member became infected and had debilitating symptoms for over eight years before being diagnosed. The reported cases of tick-borne illnesses like Lyme in the U.S. had risen “to a scary degree” she said. Even more alarming was learning it was possible to transmit spirochetes — bacteria that cause Lyme and other diseases — from a mother to a fetus through the placenta.

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Pfizer's Talzenna snags broader prostate cancer nod than AstraZeneca and Merck's rival PARP med

Fierce Pharma

The PARP inhibitor class is welcoming its second FDA approval in prostate cancer in the span of several weeks. The new approval, for Pfizer, is broader than the first but still limited. | The PARP inhibitor class is welcoming its second FDA approval in prostate cancer in the span of several weeks. The new approval, for Pfizer, is broader than the first but still limited.

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Migraine Treatments: Past, Present, and Future

Pharmacy Times

Migraines can be a primary diagnosis or a symptom of an underlying medical or psychological condition.

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Opinion: Pregnancy-related death, like Tori Bowie’s, is a far too common occurrence among Black women

STAT

The horror stories of Black women dying or coming close to death in childbirth never seem to stop coming. The most recent headlines have been about the tragic case of three-time Olympian Tori Bowie , who died in her home from childbirth complications. Her teammate Tianna Madison wrote on Instagram , “THREE (3) of the FOUR (4) of us who ran on the SECOND fastest 4x100m relay of all time, the 2016 Olympic Champions have nearly died or died in childbirth.

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AGEPHA Pharma’s LODOCO gets US FDA approval for cardiovascular disease

Pharmaceutical Technology

AGEPHA Pharma has received approval from the US Food and Drug Administration (FDA) for LODOCO (colchicine, 0.5 mg tablet) to treat cardiovascular disease. LODOCO is indicated for reducing the risk of stroke, myocardial infarction and cardiovascular death in adults with established atherosclerotic cardiovascular disease (ASCVD) or with multiple risk factors for the disease.

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STAT+: Drug middlemen catch flak at another congressional hearing

STAT

Drug middlemen once again were on the hot seat at a congressional hearing on Wednesday. The hearing by the House Education and Workforce health subcommittee was about consolidation in the hospital and health insurance sectors. No hospital or insurance company representatives testified, but JC Scott, president of the pharmacy benefit manager lobbying group Pharmaceutical Care Management Association was tapped as a witness.

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CDC advisory panel examines GSK and Pfizer RSV vaccines, set to vote today on recommended use

Fierce Pharma

The Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) will vote this afternoon on recommendations for the use of new respiratory syncytial virus (RSV) | The Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) will vote this afternoon on recommendations for the use of new RSV shots from GSK and Pfizer.

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Amid the AI gold rush, a new company forms to vet models and root out weaknesses

STAT

The market for artificial intelligence in health care is about as transparent as a brick wall. New tools achieve impressive results in published studies. But it is often difficult to compare them head to head with similar products, or tell whether they will work on different kinds of patients. A new company is promising to change that — if it can convince AI developers to expose their products to more rigorous testing.

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Merck consolidates New Jersey operations at 'reimagined' headquarters in Rahway

Fierce Pharma

Merck is back home again in Rahway, New Jersey, at the site that it established 90 years ago as Merck Research Laboratories. | Merck is back home again in Rahway, New Jersey, at the site that it established 90 years ago as Merck Research Laboratories. After being headquartered for eight years, seven miles to the north in Kenilworth, and before that, for 23 years in Whitehouse Station, 35 miles to the west, Merck has returned to its “reimagined” Rahway facility.

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New DNA test aims to make cervical cancer screening more accessible in low-income countries

STAT

A genomic test for the human papillomavirus has shown promise in early-stage trials, raising hopes that it could bolster cervical cancer screening among women living in sub-Saharan Africa, the region with the highest rates of cervical cancer deaths worldwide. The trials were documented in a study , published Wednesday in Science Translational Medicine, led by researchers from Rice University.

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ASCO 2023 – Jennifer Elliott

pharmaphorum

Pharmaphorum Editor-in-Chief Jonah Comstock spoke with Jennifer Elliott, global solid tumour lead at Takeda, about the company’s Fruquintinib product in late-stage metastatic colorectal cancer, in-licensed from HUTCHMED, and how it could provide new hope for patients with few options.

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CDC advisory panel recommends seniors ‘may’ get RSV vaccine

STAT

A panel of experts  that advises the Centers for Disease Control and Prevention on vaccinations opted Wednesday not to recommend that all seniors get a vaccine to protect against RSV. Instead, the Advisory Committee on Immunization Practices said that anyone 60 and older should be able to get one of the new vaccines — being brought to market by GSK and Pfizer — if they and their physicians think it would be worthwhile.

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“I Want Everyone to Walk in and Say, ‘Wow!’ "

Pharmacy Times

Mama Village Rx & Wellness cares for Mamaroneck community, owner considers patients like family.

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STAT Virtual Event: The Next Frontier of Drug Pricing Reform

STAT

Editor’s note: A livestream of the event will be embedded below at 1 p.m. ET. Pharmacy benefit managers are intermediaries that are supposed to negotiate lower drug costs. But does the system work for patients? And how can we fix it when it doesn’t?

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Empagliflozin, Empagliflozin Plus Metformin for Pediatric Type 2 Diabetes Approved by FDA

Drug Topics

According to the FDA, the approvals “provide a new class of medicines taken by mouth to treat pediatric T2D.

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STAT+: European companies outline opposition to proposed overhaul of pharma policy

STAT

BRUSSELS — Leaders of European pharmaceutical companies on Wednesday said that a proposed overhaul of the E.U.’s medicines policies  could render the region’s industry less competitive, the latest step in their opposition to legislation that could shorten the exclusivity period they have to sell their drugs. “A competitive industry will play a key role in a healthier Europe,” Novo Nordisk CEO Lars Fruergaard Jørgensen said at a press briefing held by

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Country Life Vitamins unveils Metabolism Reboot

Drug Store News

The supplement is designed to increase resting energy metabolism while reducing body fat, abdominal fat, waist size and visible cellulite, the company said.

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STAT+: One of biotech’s biggest financiers launches small-molecule startup, in spite of IRA’s looming shadow

STAT

It’s been nearly a year since Congress passed the Inflation Reduction Act, raising a chorus of drug executive and investor complaints that it would decimate the development of small-molecule medicines. After all, it opens the door for Medicare to negotiate the price of small-molecule drugs after nine years on the market (as opposed to 13 years for biologic drugs like vaccines, cell therapies, or gene therapies).

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Target to offer next-day delivery to customers located away from city centers

Drug Store News

​​​​​​​Target is testing an extension facility that helps it get online orders to more shoppers the day after they buy.

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