STAT

JANUARY 30, 2024

A pain relief drug developed by Vertex Pharmaceuticals succeeded in late-stage clinical trials, the company announced Tuesday, bringing the biopharma giant a step closer to launching what observers believe could be a potential blockbuster and upending decades of pharma failure in a complicated field.

128

128

Outsourcing Pharma

MARCH 11, 2024

On March 7, Celadon Pharmaceuticals plc, a leading UK-based pharmaceutical company specializing in cannabis-based medicines, unveiled promising findings from an early economic analysis of its chronic pain clinical trial, dubbed CANPAIN.

Pharmaceutical Companies 123

Pharmaceutical Companies Pharmaceutical Companies 123

Outsourcing Pharma

APRIL 18, 2024

as a space where partners can come together to collaborate, innovate, and ideate on solutions to the biggest clinical supply chain pain points. Yesterday, Thermo Fisher Scientific opened its first Innovation Lab in Center Valley, Pennsylvania.,

85

85

STAT

APRIL 8, 2024

A fully independent clinical trial researchers thought might disprove a cardiac device made by Shockwave Medical, the company that Johnson & Johnson is buying for $13 billion, ended up providing some support for the device’s utility. but was previously rejected by the U.S.

FDA 113

FDA 113

Drug Topics

DECEMBER 4, 2023

Three poster presented at the ASHP Midyear Clinical Meeting delved deeper into perioperative pain management.

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123

STAT

JANUARY 2, 2024

Here is STAT’s biotech scorecard, our regular ledger of stock-moving biotech events, for the first quarter: In December, Vertex Pharmaceuticals announced results from a mid-stage clinical trial showing its experimental, non-opioid drug reduced pain in people with diabetes who have chronic pain.

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107

The Checkup by Singlecare

APRIL 14, 2024

Ibuprofen , on the other hand, is a generic nonsteroidal anti-inflammatory drug (NSAID) that’s used to treat pain from various conditions. They are sometimes used together, particularly for people who struggle to sleep due to pain. Ibuprofen helps with the pain, and melatonin works to improve sleep quality.

Mayo Clinic 98

Mayo Clinic Labelling FDA 98

The Checkup by Singlecare

APRIL 4, 2024

Also known as period cramps, they are caused by contractions of the uterus during menstruation and triggered by the release of prostaglandins, hormone-like substances that cause pain and inflammation. This means regular exercise can go a long way toward improving symptoms if you want to relax period pains.

Hospitals 105

Hospitals 105

European Pharmaceutical Review

JANUARY 11, 2024

chronic neuropathic pain is at present, mainly managed with antidepressants… antiepileptic drugs… as well as opioids” Neuropathic pain affects over 400 million people worldwide, according to Hoba Therapeutics. What are the key current challenges in the development of pain medicines?

Medical Schools 84

Medical Schools 84

European Pharmaceutical Review

SEPTEMBER 15, 2023

Dercum’s disease is characterised by painful lipomas developing primarily on the trunk in the body. As a primary endpoint, painful lipomas dimension in the high-dose group was reduced by 51.3 As a primary endpoint, painful lipomas dimension in the high-dose group was reduced by 51.3 percent and 54.7 percent and 54.7

Compounding 119

Compounding 119

STAT

NOVEMBER 7, 2023

doctors scale back their use of  opioid painkillers , a new option for hard-to-treat pain is taking root: ketamine, the decades-old surgical drug that is now a  trendy psychedelic therapy. WASHINGTON (AP) — As U.S.

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114

STAT

FEBRUARY 15, 2024

Are 11th-hour changes ominous for clinical trials? And what’s next in pain medicine? We also discuss the latest news in the life sciences, including a twist in the future of Alnylam Pharmaceuticals, competition to Vertex Pharmaceuticals’ pain drug, and Gilead Sciences’ latest acquisition.

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STAT

AUGUST 18, 2023

Over the course of five months, women underwent egg retrievals without any pain medication. Although this procedure is typically done under heavy sedation, a nurse at the clinic had replaced fentanyl with saline. This is not the first time a health care worker has diverted pain medications away from patients.

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98

The Checkup by Singlecare

DECEMBER 26, 2023

Lower back pain and black stool causes are not usually connected. Lower back pain is very common and can be caused by poor posture, heavy lifting, osteoarthritis, menstrual cramps, and more. Most of the time, the causes of lower back pain and black stool are not the same, so experiencing both symptoms could be coincidental.

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105

The Checkup by Singlecare

JANUARY 17, 2024

Nerve pain, also known as neuropathic pain , is a type of pain that results from nerve damage to your nervous system, which includes your brain, spinal cord, and peripheral nerves. Whatever the cause, nerve pain can be uncomfortable and disruptive. “As These are the different prescription nerve pain options.

Dosage 98

Dosage FDA 98

Fierce Healthcare

OCTOBER 18, 2023

Bicycle Health, a virtual provider of opioid use disorder (OUD) care, is teaming up with Override Health, a virtual chronic pain management clinic, for a bidirectional patient referral relationship | Bicycle will refer patients to Override for chronic pain care, while Override will refer patients in need of OUD treatment to Bicycle.

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89

Hospital Pharmacy Europe

FEBRUARY 16, 2024

The importance of multidisciplinary working to address specific gender needs in pain management is highlighted in a new literature review published by the International Pharmaceutical Federation (FIP). Collaborative working can facilitate a comprehensive approach to pain management that can lead to better patient outcomes, it said.

Hospitals 52

Hospitals 52

Outsourcing Pharma

AUGUST 1, 2023

The National Health Service (NHS) research ethics committee has approved a non-cancer chronic pain clinical trial being rolled out by private health clinic LVL Health.

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94

Outsourcing Pharma

AUGUST 1, 2023

The National Health Service (NHS) research ethics committee has approved a non-cancer chronic pain clinical trial being rolled out by private health clinic LVL Health.

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93

STAT

APRIL 19, 2023

The Food and Drug Administration’s latest plan to study whether opioids are effective as a chronic pain treatment is facing significant resistance from addiction and pain care experts.

FDA 103

FDA 103

The Checkup by Singlecare

JANUARY 10, 2024

If you have pain under the right rib cage, it can be alarming, but it is quite common. Pain under the right rib cage, also known as the right upper quadrant (RUQ) of the ribs, could be due to a variety of conditions, considering this is where the pancreas, right kidney, gallbladder, liver, and part of the intestines are located.

Mayo Clinic 98

Mayo Clinic 98

STAT

FEBRUARY 1, 2024

We explain the debate over Vertex Pharmaceuticals’ novel pain drug, whose success in clinical trials comes with a sizable caveat. We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast.

FDA 95

FDA 95

The Checkup by Singlecare

DECEMBER 12, 2023

During pregnancy, women can and often do experience all sorts of aches and pains from carrying around a little—or a lot—of extra weight. Unfortunately, during pregnancy, you can’t just pop over-the-counter painkillers like ibuprofen to knock out back pain or headaches like you did before.

Immunization 105

Immunization FDA 105

The Checkup by Singlecare

MARCH 12, 2024

If you are in the market for a pain medication like Advil , you’ve probably wondered: “Is Advil ibuprofen?” In other words, Advil is a pain reliever with ibuprofen as its main ingredient. Other pain medications have branded versions. NSAIDs are FDA-approved pain medications that can decrease fever and inflammation.

Labelling 97

Labelling FDA Medication Labelling 97

pharmaphorum

NOVEMBER 2, 2022

Ben Hargreaves discovers how chronic pain could be a key area for digital therapeutics, as they offer non-addictive and effective relief from the condition. The struggle to manage pain for individuals has been one that goes back a long way in history, with one of the earliest recorded medical prescriptions being for opium.

FDA 135

FDA Dosage 135

The Checkup by Singlecare

SEPTEMBER 25, 2023

These versatile medications are used for everything from treating cold and flu symptoms to reducing fevers and relieving pain. When alternating Tylenol and Motrin, they can decrease more severe pain, such as those associated with toothaches, migraine headaches , certain surgery recoveries, sinus pain, and back pain.

Mayo Clinic 111

Mayo Clinic Dosage Labelling FDA 111

STAT

AUGUST 2, 2023

Vertex Pharmaceuticals has spent decades trying to develop molecules that reduce pain safely and potently, searching for success in a field its own executives have dubbed a graveyard for drug discovery. The drug, VX-548, blocks signals from pain-sensitive neurons before those electrical messages reach the brain.

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97

The Checkup by Singlecare

DECEMBER 1, 2023

Here’s what you need to know if you develop pain in your right shoulder blade. What causes right shoulder blade pain? Although many peptic ulcers don’t cause any noticeable symptoms , they can cause gastrointestinal symptoms as well as abdominal, chest, or back pain. Should I be worried about right shoulder blade pain? “If

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98

The Checkup by Singlecare

APRIL 18, 2024

BCPS, BCACP, a clinical pharmacist practitioner in Minneapolis. An irritated bladder could exacerbate UTI symptoms such as painful urination or a frequent urge to urinate. The reason is that spicy food can cause or aggravate indigestion and stomach pain—common side effects of nitrofurantoin.

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pharmaphorum

JULY 23, 2021

Could virtual reality tools be effective in helping patients ‘unlearn’ their chronic pain? p harmaphorum speaks to Professor Christopher Eccleston from the University of Bath’s Centre of Pain Research to find out how digital therapeutics are shaping the future of pain management. Clinical trial success.

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145

The Checkup by Singlecare

JANUARY 12, 2024

It might be a sharp, piercing pain. The permutations of pain in the lower left abdomen in men can vary, and so can the causes of the pain. The key is learning about the causes of pain in the lower abdomen in men—specifically when it occurs on the left side—and when to take action. It might be something in between.

Mayo Clinic 52

Mayo Clinic 52

Fierce Healthcare

AUGUST 17, 2023

Healthcare Outcomes Performance Company, a national leader in musculoskeletal practice and clinical outcomes management solutions, has partnered with Provider Network Solutions to establish a joint | Under a new joint venture with Provider Network Solutions (PNS) in Florida, HOPCo Network Solutions will add 1,100 new orthopedic, pain management and (..)

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98

Hospital Pharmacy Europe

JULY 6, 2023

Using opioid analgesics for patients with acute low back or neck pain offers no significant pain relief advantage compared to placebo, according to a recent randomised trial. The OPAL trial, recently published in The Lancet , investigated the efficacy and safety of a short course of an opioid analgesic for acute low back and neck pain.

Hospitals 52

Hospitals 52

Pharma Times

NOVEMBER 4, 2022

Funding will be used to broaden partnerships with the NHS and improve patient experience

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47

The Checkup by Singlecare

DECEMBER 11, 2023

If you have pain anywhere in your head, your first question is likely, “How do I make it stop?” And if the pain is in the back of your head, you may worry it’s cause for concern. There are many different types of headaches that can cause pain and pressure in the back of the head.

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105

The Checkup by Singlecare

JANUARY 23, 2024

Spasms are those painful, involuntary twitches in your muscles that typically result from an injury or overexertion. In fact, many times, your healthcare provider may recommend a combination of medications, physical therapy, or lifestyle modifications to treat pain, inflammation, and spasming.

FDA 105

FDA Labelling 105

The Checkup by Singlecare

JANUARY 26, 2024

Lower abdominal pain on the left side can be caused by an injury, inflammation, or infection of one of the following organs : Colon Small intestine Ovaries Uterus Ureters Bladder Peritoneum The kidneys are located closer to the back of the torso, but their proximity to the abdomen means kidney issues can also cause lower abdominal pain.

Mayo Clinic 52

Mayo Clinic Immunization Hospitals 52