article thumbnail

Pluvicto™ offers survival benefits for metastatic prostate cancer

European Pharmaceutical Review

PSMAfore, is a Phase III, open-label, multi-centre, 1:1 randomised study comparing the efficacy and safety of Pluvicto to a change in ARPI in 469 patients with PSMA–positive mCRPC. Pluvicto is an intravenous radioligand therapy that combines a ligand, a targeting compound with lutetium-177, a therapeutic radionuclide.

article thumbnail

Novel oral chemotherapeutic holds potential for stomach cancer patients

European Pharmaceutical Review

The availability of oral chemotherapy treatments would provide stomach cancer patients with the option of more efficacious drugs with improved tolerability in a more convenient dosage format” The poor clinical outcomes of stomach cancer make it a key target for drug development. Benefits of daily oral chemotherapy over IV.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

MHRA approves Pluvicto® and Locametz® for prostate cancer

European Pharmaceutical Review

Radioligand therapy (RLT), which combines a targeting compound (ligand) with a therapeutic radioactive atom (radioisotope), is an emerging treatment approach that may offer an alternative treatment option for some cancer patients. Its licensing makes it the first diagnostic PSMA imaging tracer to receive this status in Great Britain.

article thumbnail

Novartis’ Pluvicto presents survival benefit for castration-resistant prostate cancer

pharmaphorum

Pluvicto becomes the first PSMA-targeted intravenous radioligand therapy – combining a targeting compound or ligand with a therapeutic radionuclide or radioactive particle (in this case, lutetium-177) – to demonstrate clinical benefit in mCRPC patients before receiving taxane-based chemotherapy.

article thumbnail

Astellas, Seagen seek speedy reviews of Padcev in bladder cancer

pharmaphorum

One of the filings is to convert the ADC’s current conditional approval as a later-line therapy for urothelial cancer in patients previously treated with PD-1/L1 checkpoint inhibitors and platinum-based chemotherapy into a full approval. Both have been granted an FDA priority review with an action date of 17 August.

article thumbnail

Mirtazapine for dogs: Dosage and safety

The Checkup by Singlecare

For this reason, its use in dogs is off-label. Veterinarians may use it in a cat to prevent nausea and vomiting due to chemotherapy. So, read labels carefully. Pet parents will use tablets made for humans or mirtazapine custom-made by a compounding pharmacy. Its use as an antiemetic in dogs hasn’t been studied.

Dosage 52
article thumbnail

Who should not take probiotics?

The Checkup by Singlecare

These compounds may trigger headaches and migraines in some people. If your immune system is compromised due to medication, chemotherapy, or radiation therapy, probiotics may increase the risk of developing a bacterial or fungal infection. Biogenic amines have been found to a much lower degree in some yogurts as well.