Study: Chemotherapy to Treat Breast Cancer Increases Risk of Lung Cancer
Pharmacy Times
APRIL 19, 2024
Individuals treated with chemotherapy following a breast cancer diagnosis were more at risk of developing second primary lung cancer.
cancer 
IRA Impacts: Cancer treatment research and development
PhRMA
MARCH 23, 2023
Last month marked the one-year anniversary of the reignited Cancer Moonshot, the White House’s ambitious goal of reducing the death rate from cancer by at least 50% over the next 25 years. But more needs to be done.
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STAT+: Cancer vaccines gain momentum, after years of disappointing results
STAT
APRIL 10, 2024
SAN DIEGO — Cancer vaccines have traveled a potholed road over the last decade. But as researchers from different companies and academic institutions presented promising early data at the American Association for Cancer Research annual meeting in San Diego this week, experts said there’s a collective feeling of turning a corner.
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Opinion: Balancing hope and reality: The promise and peril of blood-based colorectal cancer screening
STAT
APRIL 24, 2024
As a gastroenterologist and cancer researcher, my mission is to help my patients live longer, healthier, and cancer-free lives. A rise in the number of younger Americans diagnosed with colorectal cancer worries me — early-age onset colorectal cancer is expected to surge by more than 140% by 2030.
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Blood-Based Test Demonstrates High Sensitivity for Colorectal Cancer
Drug Topics
MARCH 15, 2024
A blood-based cell-free DNA (cfDNA) test was able to find patients at increased risk of colorectal cancer (CRC), advanced neoplasia, and advanced precancerous lesions.
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Majority of Cancer Drugs with Accelerated FDA Approval Did Not Show Clinical Benefit After 5 Years
Drug Topics
APRIL 17, 2024
Researchers were unable to find a significant benefit for patients for the majority of cancer medications given accelerated FDA approval.
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New OTC Colon Cancer Test Makes Screening More Accessible, Affordable
Drug Topics
MARCH 25, 2024
Jeffrey Reese, president at Reese Pharmaceutical, discusses what sets ColoTest apart from other at-home colorectal cancer screening tests.
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STAT+: New liquid biopsy screening test for pancreatic cancer shows promise in early data
STAT
APRIL 8, 2024
For the vast majority of pancreatic cancer cases, the tumor grows undetected until it has already spread locally or to distant parts of the body. That’s why we have such a high degree of mortality,” said Ajay Goel, a cancer researcher at the Beckman Research Institute of City of Hope.
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Opinion: Cancer is a killer. So is the fear of it
STAT
APRIL 10, 2024
The widespread attention to the recent revelations of cancer diagnoses by Princess Catherine , actress Olivia Munn , and King Charles , among others, demonstrate yet again that cancer is a feared disease. For good reason: It is a cruel killer, the second leading cause of death in the U.S. and a top killer around the world.
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American Cancer Society expands lung cancer screening guidelines for cigarette smokers
STAT
NOVEMBER 1, 2023
Most lung cancer screening guidelines hinge on how much people smoked tobacco and when they last smoked, but the American Cancer Society now says it doesn’t matter how long ago they quit. That means the equivalent of a pack a day for 20 years, which includes two packs a day for 10 years or four packs a day for five years.
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Cancer Research UK and CRIS fund lung cancer vaccine research
Pharmaceutical Technology
MARCH 25, 2024
Cancer Research UK and the CRIS Cancer Foundation have awarded a £1.7m ($2.1m) grant for developing the lung cancer vaccine LungVax.
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STAT+: Cancer is rising among the young. Study suggests it’s because their cells are aging faster
STAT
APRIL 7, 2024
SAN DIEGO — Cancer cases among younger people have been rising for years, a trend researchers have struggled to explain. Sharing results on Sunday here at the American Association for Cancer Research annual meeting, they found that people born after 1965 were more likely to have a biological age that outpaced their chronological age.
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ADRIATIC buoys Imfinzi’s prospects in early lung cancer
pharmaphorum
APRIL 5, 2024
ADRIATIC trial finds AstraZeneca's cancer immunotherapy Imfinzi improves survival in patients with limited-stage small cell lung cancer (SCLC)
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STAT+: When a cancer drug fails, oncologists often fly blind. A precision technique might light the way
STAT
APRIL 11, 2024
Diagnosed at age 3 with acute myeloid leukemia, an aggressive blood cancer, Logan happened to have a targetable mutation that occurs in a small minority of childhood AML cases, making it possible for him to receive a precision therapy drug that — with chemotherapy — got him to a point where he could receive a bone marrow transplant.
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Researchers Develop ADC Combination Therapy to Target TRBC1-Expressed Hematologic Cancers
Pharmacy Times
APRIL 11, 2024
The antibody drug conjugate was used in combination with the anti-cancer drug SG3249, and demonstrated efficacy in mouse models after 1 week.
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FDA clears ImmunityBio’s bladder cancer drug at 2nd attempt
pharmaphorum
APRIL 23, 2024
After rejecting ImmunityBio’s Anktiva last year, the FDA has now cleared the drug as a treatment for bladder cancer, making it the biotech's first commercial-stage product
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STAT+: About half of cancer drugs given accelerated approval don’t improve survival or quality of life
STAT
APRIL 7, 2024
But about half of cancer drugs approved via this route fail to improve patient survival or quality of life in subsequent clinical trials after more than five years of follow-up , according to new findings presented Sunday at the American Association for Cancer Research annual meeting. In 2013, it took an average of 9.9
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Health Canada approves Merck’s KEYTRUDA for gastric cancer treatment
Pharmaceutical Technology
APRIL 22, 2024
Health Canada has approved Merck’s KEYTRUDA (pembrolizumab), an anti-programmed cell death protein 1 (PD-1) therapy for use in combination with fluoropyrimidine- and platinum-containing-chemotherapy as a first-line treatment for adult gastric cancer patients.
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FDA approves ImmunityBio’s Anktiva bladder cancer treatment
Pharmafile
APRIL 23, 2024
ImmunityBio has announced that the US Food and Drug Administration (FDA) has approved Anktiva (N-803, or nogapendekin alfa inbakicept-pmln) plus Bacillus Calmette-Guérin (BCG) for the treatment of patients with BCG-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS), with or without papillary tumours.
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‘Stiffness’ of cells could give early warning of cancer
pharmaphorum
APRIL 16, 2024
Researchers from the UK have developed an endoscopic device that uses 3D imaging to look at the stiffness of cells and could diagnose cancer earlier.
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Datopotamab deruxtecan by Daiichi Sankyo for Non Muscle Invasive Bladder Cancer (NMIBC) (Superficial Bladder Cancer): Likelihood of Approval
Pharmaceutical Technology
APRIL 22, 2024
Datopotamab deruxtecan is under clinical development by Daiichi Sankyo and currently in Phase I for Non Muscle Invasive Bladder Cancer (NMIBC) (Superficial Bladder Cancer).
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NCI director expresses optimism about next era of cancer research, despite shrinking budget and brain drain
STAT
APRIL 10, 2024
SAN DIEGO — Kimryn Rathmell, director of the National Cancer Institute, gestured toward the screen and asked an audience of clinicians, researchers, and patient advocates what they thought they were looking at. Projected behind her was a patchwork of purple, red, pink, and blue squares. ” Read the rest…
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Roche snags postsurgery FDA nod for Alecensa, eyes even broader lung cancer use
Fierce Pharma
APRIL 19, 2024
Roche isn’t content with Alecensa being the best-selling ALK inhibitor in metastatic lung cancer. Roche isn’t content with Alecensa being the best-selling ALK inhibitor in metastatic lung cancer.
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AACR Releases Annual Cancer Progress Report, Urges Expansion in Cancer Research
Pharmacy Times
SEPTEMBER 13, 2023
AACR has urged Congress to provide billions more in funding for cancer research, prevention efforts, and expedited review of cancer-related medical products.
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Experimental AI predicts whether cancer drugs will work
pharmaphorum
APRIL 19, 2024
Researchers in the US have developed an artificial intelligence tool that can predict how a patient will respond to cancer treatment
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HPV vaccine study finds zero cases of cervical cancer among women vaccinated before age 14
STAT
JANUARY 25, 2024
A historic new study out of Scotland shows the real-world impact of vaccines against the human papillomavirus: The country has detected no cases of cervical cancer in women born between 1988-1996 who were fully vaccinated against HPV between the ages of 12 and 13. Read the rest…
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Study: Statin Use Associated With Reduced Breast Cancer Mortality
Pharmacy Times
JANUARY 3, 2024
Investigators found that those who used statins post-breast cancer diagnosis had a lower risk of breast cancer death when the median total cholesterol decreased.
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AstraZeneca’s Imfinzi tackles another type of lung cancer with latest trial win
Fierce Pharma
APRIL 5, 2024
AstraZeneca's Imfinzi has delivered positive clinical data in another type of lung cancer, building on the immunotherapy’s existing FDA clearance in stage 3 non-small cell lung cancer and extensive | AstraZeneca's Imfinzi has delivered positive clinical data in another type of lung cancer, building on the immunotherapy’s existing FDA clearance (..)
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NICE recommends Novartis precision brain cancer treatment
European Pharmaceutical Review
APRIL 24, 2024
According to NICE, gliomas are the most common type of brain cancer in children and young people. Individuals with this aggressive brain cancer have limited treatment options, which include surgery, radiotherapy, chemotherapy, and best supportive care. Dabrafenib is administered orally twice per day as tablets.
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STAT+: Cancer vaccine startup launches with $54 million, Spark veteran as CEO
STAT
APRIL 18, 2024
A new startup focused on creating vaccines for cancers, influenza, and potentially even HIV launched Thursday with $54 million in funding. Corner Therapeutics’ Series A round was led by Ziff Capital Partners, a little-known family office started by billionaire Dirk Ziff.
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Quitting alcohol — or even drinking less — reduces risk of oral cavity and esophageal cancer, per new analysis
STAT
DECEMBER 27, 2023
Reducing or eliminating alcohol consumption reduces the risk of developing oral cavity and esophagus cancers, according to a special report from the International Agency for Research on Cancer. But more data are needed to conclude whether the same is true for several other cancer types, including colorectal, breast, and liver cancer.
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GSK’s Jemperli accepted for FDA review for endometrial cancer treatment
Pharmafile
APRIL 24, 2024
GSK has announced that the US Food and Drug Administration (FDA) has accepted its supplemental Biologics License Application (sBLA) for Jemperli (dostarlimab) in combination with standard-of-care chemotherapy (carboplatin and paclitaxel) to expand its use to the treatment of adult patients with primary advanced or recurrent endometrial cancer.
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India’s Tata Institute develops tablet for cancer recurrence prevention
Pharmaceutical Technology
FEBRUARY 29, 2024
India’s Tata Institute has developed a tablet combining resveratrol and copper that has the potential to prevent the recurrence of cancer.
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Pharmacist Role in Breast Cancer Treatment
Pharmacy Times
SEPTEMBER 22, 2023
Heather Moore, CPP, PharmD, highlights key contributions from pharmacists in breast cancer treatment and identifies current unmet needs in the treatment landscape.
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STAT+: Small studies offer hope CAR-T can fight an aggressive brain cancer
STAT
MARCH 13, 2024
A series of new studies are raising hopes that CAR-T , a process in which treatments are made by genetically editing a patient’s own white blood cells, can eventually be used to treat an incurable and deadly type of brain cancer, called glioblastoma multiforme, or GBM.
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Deep learning model ‘detects 90% of lymphatic cancer cases’
pharmaphorum
MARCH 14, 2024
Researchers have developed an artificial intelligence algorithm to assist in the diagnosis of lymph node cancer from medical images that has an accuracy of around 90%.
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Roche’s Alecensa approved by FDA as lung cancer treatment
Pharmafile
APRIL 19, 2024
Roche has announced that the US Food and Drug Administration (FDA) has approved Alecensa (alectinib) for the adjuvant treatment following tumour resection for patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC).
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STAT+: In large trial, Guardant Health’s blood test detects colon cancer, but less reliably at earliest or precancerous stages
STAT
MARCH 13, 2024
Doctors have been eagerly waiting for data on Guardant Health’s new blood-based colorectal cancer screening test, the Shield test. The hope has been that Guardant would be able to achieve an elusive goal in colorectal cancer screening: catch incipient or early colorectal cancer using nothing more than two vials of blood.
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How providers are leveraging patient engagement tools to close gaps in cancer screenings
Fierce Healthcare
MARCH 6, 2024
Millions of cancer screenings were missed during the COVID-19 pandemic. Cancer is the second leading cause of death in the U.S. As providers try to get more patients into preventive screenings, they lean on patient engagement tools to reach them.
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CureVac and MD Anderson Cancer Center Collaborate on mRNA Cancer Vaccines
BioPharm
APRIL 16, 2024
The collaboration will focus on differentiated cancer vaccine candidates in hematological and solid tumor indications to treat unmet medical needs.
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STAT+: FDA clears AI skin cancer detector for primary care doctors to use
STAT
JANUARY 17, 2024
The Food and Drug Administration cleared an AI-powered device for detecting skin cancer on Wednesday, giving primary care physicians a new way to evaluate troubling skin spots. Around 5 million skin cancers are diagnosed each year in the United States. Skin cancer is common, but most types are not that deadly when caught early.
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Opinion: Liquid biopsy for cancer recurrence creates a new kind of patient-in-waiting
STAT
OCTOBER 29, 2023
My husband’s cancer came back this summer after not being evident for almost two years. With advances in cancer surveillance, we now speak of cancer survivors being cancer-free far less frequently.
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‘Where you live shouldn’t determine how you get cancer’: An oncologist on global disparities
STAT
FEBRUARY 5, 2024
The prediction is dire: Cancer cases around the world are expected to surge 77% by 2050, a new report from the World Health Organization estimates. Women living in low-income countries are less likely to develop breast cancer (1 in 27) than if they lived in a wealthier country (1 in 12).
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MSD, Moderna cancer vaccine aces melanoma study
pharmaphorum
DECEMBER 15, 2023
MSD and Moderna’s individualised cancer vaccine mRNA-4157 has shown impressive efficacy in a phase 2b trial in skin cancer melanoma, leaving the partners speculating about a possible regulatory filing.
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