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Pharmacovigilance deep dive: risk minimisation measures

European Pharmaceutical Review

This can be achieved by reducing the burden of adverse reactions or by optimising benefits through patient selection (eg, contraindications, recommendations of use, warnings, concomitant medicine[s], or certain test parameters) and treatment management (eg, specific dosing regimen, relevant testing, patient follow-up).

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Mounjaro interactions to avoid

The Checkup by Singlecare

Drug interactions | Food interactions | Other interactions | Avoiding interactions | When to see a doctor Mounjaro (tirzepatide) is gaining popularity as a treatment for Type 2 diabetes mellitus and off-label for weight management. The ones that it does have are important, though. It is best to have everyone on the lookout for interactions.

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Can you use metronidazole for cats?

The Checkup by Singlecare

Although not FDA-approved for animals, metronidazole is used off-label in cats when prescribed in veterinary medicine. She says metronidazole is a viable treatment option for a cat with no previous adverse reactions to the antimicrobial medication. There are times when metronidazole may not be suited for your cat.

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Mupirocin side effects and how to avoid them

The Checkup by Singlecare

According to the drug label , the most common side effects of mupirocin cream are headache, skin rash, and nausea. Mupirocin interactions The mupirocin drug label doesn’t list any drug interactions. In those that do, the effects are usually mild or moderate. In clinical trials, only 8% of participants complained of side effects.

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Sulfamethoxazole-trimethoprim interactions to avoid

The Checkup by Singlecare

Levels of the drug in our bloodstream play a role in determining how much adverse effect risk is present. SMX-TMP can increase the risk of methotrexate adverse reactions , particularly when it comes to bone marrow suppression, which leads to anemia and low platelets (clotting cells).

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Nextstellis®: A new drug update 

Birth Control Pharmacist

Adverse Reactions. The most common adverse reactions (>2%) were bleeding irregularities, dysmenorrhea, headaches, mood disturbance, increase weight, acne, decrease libido and breast symptoms. Breakthrough bleeding was present in 33.8% Managing Adverse Effects of Hormonal Contraceptives.”

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FDA Unveils Its Own Medical Queries—A Standardized Approach for Grouping MedDRA Preferred Terms that Will Impact NDA/BLA Safety Analyses and Drug Labeling

The FDA Law Blog

By Ellis Unger, Principal Drug Regulatory Expert — On September 14, 2022, FDA/CDER/Office of New Drugs, in collaboration with the Duke-Margolis Center for Health Policy, hosted a virtual meeting on advancing premarket safety analytics , including sessions on new FDA Medical Queries and standardized presentations of safety data.