Pharmaceutical Technology

MAY 12, 2023

The agent is a human epidermal growth factor receptor 2 (HER2)-targeting ADC that utilises Eisai’s chemotherapy Halaven (eribulin) as its payload. The drug became a blockbuster last year, with sales reaching $1.9bn, up from $599m in 2021. The company generated almost $2bn in revenue in 2022, a close to 25% increase from 2021.

Chemotherapy

Pharmaceutical Technology

AUGUST 12, 2022

billion in 2021 and is forecast to reach $2.4 By 2028, the market is expected to reach $25 billion, with a compound annual growth rate (CAGR) of 46.6%. According to GlobalData’s Epidemiology database, there were 5,446 incident cases of DLBCL in the UK in 2021. billion by the end of 2022.

Immunization

Pharmaceutical Technology

FEBRUARY 13, 2023

This makes early R&D less risky, as many lead compounds are discontinued due to inadequate pharmacokinetic profiles and require excessively high dosages to be pharmaceutically active. Both degraders, ARV-110 (bavdegalutamide) and ARV-766, are being developed by Arvinas.

Chemotherapy

Blog: Ask a Student Pharmacist

JUNE 21, 2023

Jiashu Xie, PhD eomizowh Wed, 06/21/2023 - 10:11 Expand all + Biography Research Summary Current research in the Pharmacokinetics (PK) lab has focused on profiling the in vitro ADME (absorption, distribution, metabolism, and excretion) and in vivo PK properties of lead compounds from medicinal chemistry efforts. 2021; 13(12): 2508.

Compounding

The Thyroid Pharmacist

SEPTEMBER 20, 2024

Chemotherapy agents: Chemotherapy agents can lead to constipation in a variety of ways such as slowing the movements of the intestinal tract or creating inflammation that disrupts digestive function. 2021 Dec 28;14(1):122. 2021 Jan 28;13(2):421. Published 2021 Apr 13. doi: 10.3390/nu14010122. J Am Coll Nutr.

Health and Personal Care Stores

European Pharmaceutical Review

JULY 5, 2022

The availability of oral chemotherapy treatments would provide stomach cancer patients with the option of more efficacious drugs with improved tolerability in a more convenient dosage format” The poor clinical outcomes of stomach cancer make it a key target for drug development. Benefits of daily oral chemotherapy over IV.

Chemotherapy

pharmaphorum

DECEMBER 23, 2020

While Trodelvy is already conditionally approved in the US, the data showing the drug improved overall survival compared with chemotherapy could be enough for it to clinch a permanent licence in the US. months in patients treated with chemotherapy. In the 500 patient trial, patients treated with Trodelvy lived for a median of 12.1

Chemotherapy

pharmaphorum

AUGUST 5, 2021

The interface is highly hydrophobic, hence any compounds containing water would be repelled. It is a popular method in systems biology, requiring fewer compounds to be screened in bioassays, reducing time and cost. The surface of PPIs, known as the interface, is typically flat with a limited number of grooves.

Compounding

Druggist

APRIL 29, 2021

Eliquis is still protected by patent rights in the UK, with exclusive availability rights until 2026 (IPO, 2021). . Apixaban stops the production of enzymes (chemicals) required for the production of fibrin , a compound (protein) that plays a role in the clotting of the blood. Patients who have cancer or receive chemotherapy.

Chemotherapy

The Thyroid Pharmacist

SEPTEMBER 1, 2023

The fluorine anion (negatively charged ion), or any of the compounds containing the anion, are termed fluorides. 26] A study published in 2021 which examined 446 children aged 7 to 12 years, found that thyroid volumes increased in accordance with the volume of fluoride in their urine. [27]

Adverse Reactions

Pharmaceutical Technology

MARCH 29, 2023

AlgoTx remains on track to start enrolling subjects of a Phase II study of its compound ATX01 for the rare condition erythromelalgia in Q2 2023, says CEO Stéphane Thiroloix. Stéphane Thiroloix, CEO of AlgoTx Alongside erythromelalgia, the company is testing ATX01 in a Phase II study in chemotherapy-induced peripheral neuropathy (CIPN).

Chemotherapy

The Checkup by Singlecare

DECEMBER 1, 2023

A meta-analysis of six studies evaluating the relationship between fat intake and male testosterone levels published in 2021 revealed that low-fat diets moderately decrease T-levels in men via a reduction in testicular testosterone production. However, the review did note that more controlled trials are needed to confirm the findings.

Mayo Clinic

The Thyroid Pharmacist

JULY 8, 2022

It’s important to note that selenium may also interact with other supplements and medications, such as cholesterol-lowering statin drugs, antacids, chemotherapy drugs, corticosteroids, niacin, and even birth control pills. 17 November 2021 | [link]. Institute of Medicine (US) Panel on Dietary Antioxidants and Related Compounds.

Dosage

The FDA Law Blog

FEBRUARY 11, 2024

Potency has increased since the last scheduling review, with the average tetrahydrocannabinol (“THC”) potency of marijuana seized by DEA spiking from 3.96% in 1995 to 15.34% in 2021. Studies have found that marijuana access has public health benefits by reducing the rates of opioid use and opioid deaths.

Controlled Substances