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Intratumoural viral delivery improves glioblastoma survival

European Pharmaceutical Review

The viral therapy “aims to awaken the patient’s immune system and trigger a healing from within,” Dr Fueyo commented. After injection, patients that respond well develop inflammation inside the tumour, triggering an immune response that first kills the virus.” This makes it difficult to treat the cancer with immunotherapy.

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First CAR T-cell therapy recommended on NHS

European Pharmaceutical Review

CAR T-cell therapy engineers a patient’s own immune cells (T-cells) to detect, target and destroy cancer cells. Could CAR T therapies be manufactured in one day?

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Keytruda approved as first-line advanced cervical cancer therapy

pharmaphorum

Keytruda (pembrolizumab) can be used in combination with chemotherapy, with or without bevacizumab, to treat patients with persistent, recurrent or metastatic cervical cancer where the tumour expresses a certain level of PD-L1. Some cancer cells contain large amounts of PD-L1, which helps them to evade the body’s immune system.

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Jiashu Xie, PhD

Blog: Ask a Student Pharmacist

2016; 13(1): 1-12. 2016; 26(21): 5177-5181. 2016; 7: 225-229. 2016; 59(13): 6136-6148. 2016; 24(11): 2410-2422. 2016; 59(7): 2928-2941. 2016; 60(4): 2318-2325. 2016; 24(4): 686-692. Publications He T, Edwards TC, Majima R, Jung E, Kankanala J, Xie J , Geraghty RJ, Wang Z. Retrovirology.

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A history of blood cancer treatment

pharmaphorum

Crucially, he observed a connection between certain tumours and inflammation, noting that neoplastic tissues were often covered with leukocytes of the immune system. 1942 – Chemotherapy moves from trenches to treatment . 1942 – Chemotherapy moves from trenches to treatment . 1907 – The magic bullet of immunotherapy.

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Amitriptyline for NERVE PAIN (REVIEWED)

Druggist

Diseases , on the other hand, are known causes of nerve pain, for example, obesity, diabetes, stroke (ibid) or chemotherapy-induced neuropathic pain in cancer patients. 2003) and additionally may affect the immune system which plays a big part in neuropathic pain (Fornasari, 2017). Epub 2016 Dec 29. Sommer C, Cruccu G.

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Nicolas Paquette-Lamontagne, VP, Medical Affairs at Blueprint Medicines Shares his Views on Clinical Data of Ayvakit for Patients with Systemic Mastocytosis

PharmaShots

In SM, activated mast cells release histamine and other proteins that promote allergic reactions, inflammation, and other immune responses, and people living with the disease. Traditional therapies have included multi-kinase inhibitors, chemotherapy, and symptom-directed treatments.