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Six months after authorization, what do we know about Paxlovid?

pharmaphorum

As COVID-19 cases rise once again and the federal government gears up to increase distribution of Paxlovid, we thought we’d take this opportunity to review information about the drug and share new information that has come to light since it was first approved. What is Paxlovid and how was it developed? What are its side effects?

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A doctor’s humbling journey treating long Covid: ‘The second we think we know what we are doing, we fall flat on our face’

STAT

I first met Wes Ely in 2016, when I wrote about ICU delirium and Ely’s attempts, as a critical-care physician at Vanderbilt University Medical Center, to urge fellow health care workers to rethink the use of heavy sedation in ICUs.

Hospitals 116
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Opinion: After 20 years in rehabilitation research, my young daughter’s traumatic brain injury transformed my mind and my career

STAT

Returning home after five months in the hospital, the real journey began : How do we best care for and support our daughter, who cannot do any daily activities on her own, cannot walk or talk, and has become cognitively impaired? What used to be the organized chaos of caring for three young children became just chaos.

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Advice For New Pharmacists: Lessons Form The Front Lines

IDStewardship

Ask yourself, if I do not make this improvement to this drug regimen, will someone else do it and will the patient have a worse time without the improvement? See if they do not mind sharing which plan they have and what they have learned from it. It is a totally different game now. ” mentality.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? Learning Objectives: Dose-response curves and patient treatment: How do pharmacologic and toxicologic principles apply to the dosing of drugs in clinical development? A recent draft from the FDA provides valuable insight.

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STAT+: Mount Sinai’s responses to STAT’s questions about the Living Brain Project

STAT

Can you describe for us what the Living Brain Project has accomplished, to date, and what promise the investigators feel it holds for future brain research? As part of its reporting on Mount Sinai and the Living Brain Project, STAT sent a list of written questions to Mount Sinai. Below is a copy of the questions and responses.

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STAT+: Patient advocates clash over wisdom of ‘approving drugs faster and faster’

STAT

We basically put access out there as this talisman of hope, but we don’t compel the companies that give us answers about what these drugs do in our bodies.” These days, though, Gonsalves sounds uneasy — if not mournful — of the world he helped build. 

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