Remove tag immune-tolerance
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ASH: Argenx cues up a second use for efgartigimod

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Dutch biotech Argenx is on course to add another rare disease indication to the label of its FcRn blocker Vyvgart – primary immune thrombocytopenia (ITP) – thanks to new data reported at the ASH annual meeting.

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Roche nabs breakthrough tag for TIGIT cancer immunotherapy

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Like PD-L1, TIGIT is thought to act as a molecular brake that stops T cells from attacking tumours, and tiragolumab is currently leading the pack among drugs targeting the immune checkpoint. The post Roche nabs breakthrough tag for TIGIT cancer immunotherapy appeared first on.

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After a slow start for expensive CAR-T therapies, drug developers revisit oral therapies for blood cancer

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In the last few years, the first generation of cell therapies has offered a powerful new way of treating blood cancers, with CAR-T technology reprogramming patients’ immune system to fight cancer. Treatment has been generally well-tolerated, with the majority of on-target toxicities being mild or moderate in severity.