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Minimizing Anticholinergic Adverse Effects – Case Study

Med Ed 101

If you work in geriatrics to any extent at all, you’re likely familiar with anticholinergic activity. If you’ve learned anything, you know that more is NOT better when it comes to anticholinergic adverse effects. Let me share […].

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Promethazine interactions to avoid

The Checkup by Singlecare

It works by blocking the receptors and effects of histamine, dopamine, and acetylcholine chemicals. While promethazine can be an effective medication, it may interact with prescription drugs, over-the-counter medications, and herbal supplements. Oversedation, respiratory depression, and other serious side effects can occur.

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Olanzapine interactions to avoid

The Checkup by Singlecare

Olanzapine interacts with medications that impact the central nervous system, like antidepressants, other medications that lower the seizure threshold, and medications with anticholinergic effects. Anticholinergic medications block the activity of the neurotransmitter acetylcholine in both the central and peripheral nervous systems.

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Donepezil interactions to avoid

The Checkup by Singlecare

However, donepezil use comes with a risk of side effects including cardiac effects, loss of appetite resulting in weight loss, and the development of muscle cramps. Donepezil interacts with anticholinergic agents, antipsychotic agents, medications that slow the heart rate, and other medications that impact cardiac conduction.