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Avatrombopag (Doptelet; Sobi) has been approved by the FDA for the treatment of pediatric patients aged 1 year and older with persistent or chronic immune thrombocytopenia (ITP) who have had an insufficient response to a prior therapy. The decision is based on clinically meaningful data from the AVA-PED-301 study (NCT04516967).
2 Pharmacists can play a large role in the management of IBD, especially because medication nonadherence is common, leading to increased flares, hospitalizations, and complications. Additionally, pharmacists can make sure that patients have updated immunizations, especially for patients who are on immunosuppressive therapy.
In an interview with Pharmacy Times at the 2025 Oncology Pharmacists Connect (OPC) meeting, Scott Soefje, PharmD, MBA, BCOP, director of pharmacy at MayoClinic, focused on the evolving role of pharmacists in healthcare, highlighting their increasing presence in outpatient settings to enhance efficiency and patient care.
1 “Eligible outcomes included changes in health-related quality of life, medication adherence, hospitalization rates, inhalation techniques, or disease-related knowledge." " Finally, pharmacist-led interventions were all conducted in community pharmacies, outpatient clinics, or hospital settings. MayoClinic Staff.
MayoClinic. RAD 2025: Long-term data on Nemluvio® (nemolizumab) demonstrate its favorable safety profile and sustained and increased improvements in itch and skin lesions in patients with atopic dermatitis up to two years. News release. June 6, 2025. Accessed June 16, 2025. Atopic Dermatitis. News release. May 15, 2024. Ferruggia K.
Have you observed these immune-related toxicities in your practice, and if so, how are they being managed? All patients should have immunotherapy first. Pharmacy Times : As immunotherapies expand into the solid tumor space, clinicians are reporting cases of ICANS and CRS. It was approved last year.
This act…allowed a pathway for manufacturers to create a ‘copy’ of a licensed patent product to make it cheaper and more discounted,” Soefje, director of pharmacy cancer care services and associate professor of pharmacy at MayoClinic in Rochester, Minnesota, said at the HOPA conference.
MayoClinic. link] Newsletter Stay informed on drug updates, treatment guidelines, and pharmacy practice trends—subscribe to Pharmacy Times for weekly clinical insights. Sirtex Medical’s SIR-Spheres ® Y-90 Resin Microspheres Receive FDA Approval for the Treatment of Unresectable Hepatocellular Carcinoma. News release.
These treatments are already in widespread use across health systems, from MayoClinic’s 9 active and 5 pending to University of California (UC) San Diego Health’s 12 active and 5 under review. At Children’s Hospital of Philadelphia (CHOP), eligible patients can access 12 advanced therapeutics and 8 more in the pipeline.
MayoClinic. FDA approves updated label for Lilly's Kisunla (donanemab-azbt) with new dosing in early symptomatic Alzheimer's disease. Eli Lilly and Company. News release. July 9, 2025. Accessed July 9, 2025. Alzheimer’s Disease. News release. November 8, 2024. Accessed July 9, 2025. link] Gallagher A. Pharmacy Times.
In an interview with Pharmacy Times , Shaji Kumar, MD, consultant and research chair of the Division of Hematology in the Department of Internal Medicine at MayoClinic, discussed emerging data from the phase 2 RedirecTT-1 study (NCT04586426).
MayoClinic. link] Newsletter Stay informed on drug updates, treatment guidelines, and pharmacy practice trends—subscribe to Pharmacy Times for weekly clinical insights. FDA Grants Fast Track Designation for TRE-515 in Combination with Radiation Therapy for the Treatment of Metastatic Castration Resistant Prostate Cancer.
LN is a complication of SLE that occurs when the immune system mistakenly attacks the kidneys, leading to inflammation and potential organ damage. 1 With this approval, belimumab is now accessible for patients and their caregivers at home, rather than needing to travel to a hospital or clinic to receive treatment.
1 “Having the Benlysta autoinjector provides a much-needed option that can help reduce the burden of frequent clinic visits for treatment and add greater flexibility for children and their families when considering continuity of care and routines of daily life." MayoClinic. REFERENCES 1. News release. June 24, 2025.
1 "Immunotherapy given neoadjuvantly may not be the appropriate treatment strategy for patients with high fusion,” said Kaushal Parikh, MD, from MayoClinic. “In Mandatory ALK fusion testing should become part of the standard of care to better personalize treatments to a patient’s specific ALK variant.
Following, HR+, HER2- early breast cancer is a common subtype where the cancer cells have estrogen and progesterone receptors but do not have excessive amounts of the HER2 protein, according to MayoClinic. MayoClinic. Clinicaltrials.gov: NCT05306340. Updated April 15, 2025. Accessed June 13, 2025. News release.
READ MORE: COVID-19 Hospitalizations Disproportionately Impacted Black, Hispanic Children “Resilience is the extent to which we can bounce back from adverse events, cope with stress, or succeed in the face of adversity,” said Cindy Bergeman, PhD, MS, professor of developmental psychology at the University of Notre Dame. MayoClinic.
MayoClinic. Akkooi A, Mandala M, Kicinski M, Primary analysis of the EORTC-2139-MG/Columbus-AD trial: A randomized trial of adjuvant encorafenib and binimetinib versus placebo in high-risk stage II melanoma with a BRAF-V600E/K mutation. J Clin Oncol. 43, 2025 (suppl 17; abstr LBA9500). doi:10.1200/JCO.2025.43.17_suppl.LBA9500.
MayoClinic. link] Newsletter Stay informed on drug updates, treatment guidelines, and pharmacy practice trends—subscribe to Pharmacy Times for weekly clinical insights. JAMA Netw Open. 2025;8(7):e2520011. doi:10.1001/jamanetworkopen.2025.20011 2025.20011 2. Long-term obesity and biological aging in young adults. EuerkAlert!
MayoClinic. " 1 REFERENCES 1. Boston Scientific receives FDA approval for expanded labeling of FARAPULSE™ Pulsed Field Ablation System. News release. July 7, 2025. Accessed July 7, 2025. Atrial fibrillation. Accessed July 7, 2025. Boston Scientific. FARAPULSE™ Pulsed Field Ablation System. Accessed July 7, 2025.
The antibody – called lenzilumab – targets colony stimulating factor 2 (CSF2) and granulocyte-macrophage colony stimulating factor (GM-CSF), two cytokines that are linked to the runaway immune response that can result in serious lung damage in COVID-19.
But young children, older adults, and individuals with weakened immune systems are at high risk of severe, potentially life-threatening RSV illness. Infants have a high risk because their airways may be small enough to close up when inflamed and their immune systems aren’t yet fully developed. Is there a vaccine for RSV?
Reasons you would not have a thyroid When you visit your primary care provider for an annual physical, they will likely feel the front of your neck to check for nodules or other abnormalities, says Eric Ascher, DO , family medicine physician at Northwell Health’s Lenox Hill Hospital in New York.
This is a common medical condition: Sinus infections affect about 35 million Americans annually and are responsible for almost 16 million hospital visits each year. These foods will not necessarily cure sinus infections but complement other therapies by providing benefits such as solid immunity and reduced inflammation.
The immune system releases histamine in response to unfamiliar proteins (allergens), including pollen, mold, dust mites, and pet dander. Antihistamines work by blocking the action site of a chemical in the body called histamine,” says Dr. Joseph.
“Allergies are a condition in which the immune system reacts abnormally to a foreign substance,” explains David Henry Hiltzik, MD , the interim chair of otolaryngology at Northwell Health’s Staten Island University Hospital in New York.
Allergens, he explains, trigger the release of chemicals like histamine from our mast cells (immune cells), leading to congestion and other inflammatory symptoms. Instead of taking vitamin C when you get sick, Dr. Husain says it’s a good idea to take a vitamin C supplement preventively because it boosts the immune system.
Watchful waiting allows the immune system to fight the infection. MayoClinic recommends that individuals with recurrent swimmer’s ear hold a blow dryer at least 1 foot from their ear, with the blow dryer on the lowest setting to remove all traces of moisture.
While diverticulitis is not always serious, severe cases may require hospitalization or surgical intervention. Celiac disease is an immune system-related response to gluten that can cause sharp pain in the belly, diarrhea, weight loss, gas, and very bad-smelling stools. appeared first on The Checkup.
There are risk factors that increase the chance of developing a UTI, including using diaphragms or spermicidal agents for birth control, menopause, blockages in the urinary tract such as kidney stones, sexual activity, recent catheter use, and a suppressed immune system. However, some severe cases may require treatment in a hospital.
A complicated UTI may require a longer course of antibiotics and may require treatment in the hospital. According to the MayoClinic , up to 75% of women will have at least one yeast infection in their lives, with some women experiencing two or more. A kidney infection is an example of a complicated UTI.
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