article thumbnail

Oral COVID Agents

Pharmacy Friday Pearls

18 years Administration Oral Oral Oral PK/PD MOA: Nirmatrelvir – inhibitor of the SARS-CoV-2 main protease Prevents viral replicationRitonavir is a CYP3A inhibitor included to increase nirmatrelvir plasma levelsRitonavir alone has NO activity against SARS-CoV-2 Time to peak: Nirmatrelvir: 3 hrs & Ritonavir: 3.98 Introduction.

article thumbnail

Pneumonia symptoms: What are the early signs of pneumonia?

The Checkup by Singlecare

Pneumonia is often mild to moderate, requiring only outpatient treatment. Rarely can it be severe enough to require intensive care in a hospital? Risk factors of pneumonia are age older than 65, chronic obstructive pulmonary disorder ( COPD ), HIV infection , weakened immune system and smoking. Treatment depends on the cause.

article thumbnail

Ivermectin: A therapeutic approach to reduce high-risk cases of COVID

Druggist

With an ongoing vaccination program globally, experts hope that a large world population will soon get a vaccine that protects against corona. Additionally, this drug is also known as anti-parasite successful against all viruses like HIV, Dengue, Influenza , and Zika virus. How effective is Ivermectin for Corona?