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Gilead hit with FDA clinical hold for batch of HIV trials

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has placed a clinical hold on several of Gilead’s trials evaluating two HIV treatment candidates, though the rest of the drugmaker’s diverse pipeline remains unaffected. Gilead is considered the leading big pharma in HIV treatments. Shares in Nasdaq-listed Gilead opened 0.3%

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ADA 2025: Advances in Type 2 Diabetes Management With Tirzepatide

Pharmacy Times

The presentation emphasized early intervention and personalized treatment plans in managing type 2 diabetes, shifting from "treating to failure" to "treating to target." It is not indicated for type 1 diabetes and carries a boxed warning for thyroid C-cell tumors, with unknown risk in humans.

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Impact of Patient Access to Care on Rates of Febrile Neutropenia Post Inpatient Administration of a Colony-Stimulating Factor

Pharmacy Times

Although the use of colony-stimulating factors (CSFs) is well-established in mitigating severe FN, existing literature suggests there is only an approximate 3% difference in FN rates between various CSF agents. Utilizing colony-stimulating factors (CSFs) decreases the incidence of severe FN.

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FDA Approves Meloxicam Injection For Moderate-to-Severe Pain in Adults

Pharmacy Times

The convenience of once-daily dosing and a rapid IV bolus administration may offer workflow efficiencies in hospital or surgical settings, where minimizing polypharmacy and streamlining medication administration are important goals. 2 REFERENCES 1.

FDA 73
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The Checkup by Singlecare - Untitled Article

The Checkup by Singlecare

Paxlovid can be a useful drug that can decrease the risk of hospitalization or death in high-risk individuals with COVID-19. It’s also recommended to discontinue atorvastatin and rosuvastatin during treatment with Paxlovid. In addition, other contraceptives should be continued until one menstrual cycle after stopping Paxlovid.

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Oral COVID Agents

Pharmacy Friday Pearls

18 years Administration Oral Oral Oral PK/PD MOA: Nirmatrelvir – inhibitor of the SARS-CoV-2 main protease Prevents viral replicationRitonavir is a CYP3A inhibitor included to increase nirmatrelvir plasma levelsRitonavir alone has NO activity against SARS-CoV-2 Time to peak: Nirmatrelvir: 3 hrs & Ritonavir: 3.98 Introduction.

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How Balancing Iron Levels Can Help Your Thyroid

The Thyroid Pharmacist

And as we’ve seen, even with supplementation, you need to address your root causes to prevent iron supply and demand challenges. Autoimmune Gastritis Autoimmune gastritis is a chronic inflammatory disease that occurs when your immune system attacks your stomach lining. Too much iron/ferritin can be a problem.