Sat.Aug 01, 2020 - Fri.Aug 07, 2020

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How does HTA for orphan drugs differ across Europe?

pharmaphorum

New research looks at the factors that speed up and slow down HTA appraisals for rare disease medicines across Europe. Rare diseases drugs have always faced challenges when it comes to HTA approvals, even as governments bring in more regulatory policies that make their path through assessment easier. Several factors make it difficult for HTA bodies often to assess orphan drugs, including a lack of robust trial data due to difficulties in finding patients, the absence of randomised controlled tri

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Research partnership delves into opioid alternatives

Outsourcing Pharma

Neurasic Therapeutics is borne from a collaborative effort intended to advance development of opioid-alternative pain relief.

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Otrivine Extra Dual Relief – 8 facts YOU must know

Druggist

Otrivine Extra Dual Relief is a pharmacy only medication and the only over the counter product containing ipratropium bromide for the management of congestion and runny nose caused by colds. This post summarises the essential information about Otrivine Extra Dual Relief nasal spray. 1. Otrivine Extra Dual Relief indicated use Otrivine Extra spray is used for the management of congestion and rhinorrhoea caused by colds. 2.

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6 Key Takeaways from HBA’s “Virtual Best Practices: Clarity, Collaboration and Connecting”

Pharma Marketing Network

Recently, the Healthcare Businesswomen’s Association (HBA) held a webinar entitled, Virtual Best Practices: Clarity, Collaboration and Connecting , which dove into the topic of “Zoom fatigue,” a new, commonly used term defined by the draining feeling you experience after a day of long, unnecessary meetings. We are all facing new challenges in the rapidly changing work environment.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Pfizer signs deal with Gilead to manufacture COVID-19 antiviral remdesivir

pharmaphorum

Pfizer has signed a multi-year agreement with Gilead to manufacture and supply the COVID-19 antiviral remdesivir, which is also being tested in combination with other drugs in an effort to fight the pandemic. Under the terms of the agreement Pfizer will become one of several external partners who manufacture the investigational treatment for the disease.

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Senate bill proposes study of the US pharma supply chain

Outsourcing Pharma

The bipartisan bill calls for an assessment of the countryâs pharma supply chain, including potential vulnerabilities and impact of foreign manufacturing.

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A mini review on nanosuspension drug delivery system : An innovative approach for poorly aqueous soluble drugs

Pharma Tutor

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Fearing Brexit chaos, UK asks pharma to build six-week drug stockpile

pharmaphorum

The UK government has asked pharma companies to build a six-week stockpile of drugs and find alternative shipping routes to the congested Dover-Calais crossing as the country heads for Brexit at the end of the year. In a letter , Steve Oldfield, chief commercial officer at the Department of Health and Social Care, said the government is focused on preventing potential disruption to any categories of medical supplies.

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ACD/Labs: tech can overcome supply chain challenges

Outsourcing Pharma

A leader from the scientific software provider discusses the most challenging obstacles in the pharma supply chain, and solutions that can conquer them.

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Cosentyx wins EU approval for first-line paediatric psoriasis

Pharma Times

Low-dose and high-dose Cosentyx is effective in rapidly improving skin symptoms and quality of life

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Pre-Interview Tips for Pharmacy Professionals | Tip #1

indispensable health

Pre-Interview Tips for Pharmacy Professionals | Tip #1 with Tom Alig | Vice President of Staffing at Indispensable Health Hi, I am Tom Alig, VP of Staffing with Indispensable Health. I’ve been recruiting pharmacists and pharmacy technicians since 2004, and I’ve seen the things good candidates do to separate themselves, and I’ve seen the mistakes that some candidates make.

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Redx shares soar after IPF drug licence deal with AstraZeneca

pharmaphorum

Shares in Redx Pharma were soaring this morning after it licensed its preclinical fibrotic disease drug RXC006 to AstraZeneca. The company’s shares were valued as high as 95p on the London Stock Exchange following the announcement, the highest they had been since 2015. AstraZeneca has bought an exclusive global licence to develop and market RXC006, a porcupine inhibitor for fibrotic diseases including idiopathic pulmonary fibrosis (IPF).

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This week's FDA COVID-19 news

Outsourcing Pharma

The agency continues to provide resources for the life-sciences industry, approve tests, and take action against companies offering false treatments.

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Genmab/Janssen’s Darzalex combo hits the mark in phase 3 study

Pharma Times

Subcutaneous formulation of Darzalex in combination with pomalidomide and dexamethasone meets primary endpoint

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Drugs That Cause Hyperthermia – Can You Name Them?

Med Ed 101

While not incredibly common, medications can cause dysregulation of our body’s thermoregulation process and cause a rise in core temperature in the presence of normal core body temperature which leads to hyperthermia. Before we get to the drugs that cause hyperthermia, let’s review thermoregulation. Our body is able to regulate our core temperature to keep […].

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Mental health platform helps students facing exam results during pandemic

pharmaphorum

The UK digital mental health support platform Kooth has joined with five of the UK’s well known Instagram influencers to launch a campaign to help students deal with the pressures of exam results season. The campaign encourages the hundreds of thousands of students waiting to receive their exam results, to stay mentally strong and know they have access to support, if needed.

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IBM: speed is vital with COVID-era trials

Outsourcing Pharma

A leader from IBM Watson Health talks about how its advanced EDC solution is geared toward helping studies save precious time and conserve costs.

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Pharma’s reputation has climbed during COVID-19 pandemic, study finds

Pharma Times

Roche, AstraZeneca, Novo Nordisk and Sanofi all climbed index rankings

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Free Pharmacogenomics Exam Questions – Can You Pass the Test?

Med Ed 101

As of August 1st, 2020, pharmacogenomics has been added to the BCMTMS exam content outline. We’ve updated our material to include a review of pharmacogenomic principles and common medications that may be affected by genetic variations. In addition, we’ve added pharmacogenomics quiz questions to our quiz bank. I wanted to share a sample of our […].

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FDA approves GSK’s Blenrep for advanced multiple myeloma

pharmaphorum

The FDA has approved GlaxoSmithKline’s multiple myeloma drug Blenrep, a first-in-class potential blockbuster that will be used in advanced disease. Blenrep (belantamab mafodotin) has been approved in patients who have received at least four therapies including an anti-CD38 such as Darzalex, a proteasome inhibitor and an immunomodulatory agent. This is an accelerated approval based on response data and GSK may need survival data from a larger trial to keep the drug on the market in the longer ter

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Minakem: collaboration could elevate pharma supply chain

Outsourcing Pharma

Representatives from the CDMO offer perspective on problems plaguing the global pharma supply chain, and possible ways to improve them.

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Janssen’s depression nasal spray Spravato bags new FDA approval

Pharma Times

Drug approved to treat major depressive disorder with acute suicidal ideation or behaviour

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Tackling multimorbidity through collaboration

pharmaphorum

As populations age, multimorbidity becomes an increasingly pertinent issue for healthcare systems. A new action group from the ABPI seeks to bring the NHS, academia and industry together to find new ways to address the problem. The Association’s Dr Sheuli Porkess and Professor Janet Lord from the University of Birmingham tell us more. Multimorbidity is an increasing issue for healthcare and the NHS.

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Decentralised trials – aided by tech – could boost clinical research

pharmaphorum

Bringing clinical trials to patients – rather than the reverse – could be the key to improving recruitment into studies and making them faster, cheaper and more likely to succeed, according to one clinical research organisation (CRO). There’s already plenty of support from regulators for virtual or ‘decentralised’ trials, including from former FDA Commissioner Scott Gottlieb who said last year that the agency was encouraging adoption of this approach to make trials more “agile and efficient”, as

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Government warned over test and trace as UK schools prep to reopen

pharmaphorum

The current level of test and trace in the UK is inadequate to prevent a sharp increase in coronavirus infections when schools reopen in September and there is further relaxation of social distancing rules, according to scientists. A second wave of COVID-19 could be avoided if enough people are tested and traced, according to the team from University College London and the London School of Hygiene & Tropical Medicine.

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Biogen signs $2.1 billion Parkinson’s disease deal with Denali

pharmaphorum

Biogen has bought a licence to co-develop and co-market potential Parkinson’s disease drugs with US biotech Denali, in a deal worth more than $2.1 billion. Denali has been working on small-molecule compounds capable of crossing the blood-brain barrier and Biogen has bought a licence to co-develop and co-market compounds known as LRRK2 inhibitors in Parkinson’s disease.

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Cerner and LRVHealth invest $6m in digital health firm Xealth

pharmaphorum

Health technology firms Cerner and LRVHealth have invested $6 million in Xealth to scale up its business offering digital health tools to patients and clinicians. The companies said the new relationship aims to give patients control over their own digital data so they can be more engaged in their treatment plans. Cerner and LRVHealth join Xealth’s other investors Atrium Health, Cleveland Clinic, Froedtert and the Medical College of Wisconsin, MemorialCare Innovation Fund, Providence Ventures and

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TraceLink unveils FDA DSCSA pilot program results

Outsourcing Pharma

Initial information from the life-sciences specialistâs pilot program shows potential pathways to solving common pharma supply chain challenges.

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Pharma’s rep soars on back of COVID-19, says FutureBrand

pharmaphorum

The perception of pharma and medical product companies has surged forward since the start of the COVID-19 pandemic, but they still lie mostly outside the top-rated firms in the FutureBrand Index. Roche, AstraZeneca, Novo Nordisk, and Sanofi all shot up the rankings in the first edition of the report since the start of the coronavirus crisis, but the big loser was Gilead Sciences, falling 71 places to 74 in the list since the last edition in 2018.

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Premier Research: ePRO data improves upon paper-based reporting

Outsourcing Pharma

Use of electronic patient-recorded outcome data can lead to more accurate trial data, and a better patient experience, according to the CRO.

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COVID-19 highlights US dependence on foreign pharma: CEO

Outsourcing Pharma

An executive from Pharmaceutical Associates Inc. believes bringing drug manufacturing back to the country will help avoid shortages and other disasters.

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Medidata: COVID-19 forcing trials to adapt

Outsourcing Pharma

A leader at the companyâs Acorn AI Labs talks about ways the pandemic has impacted the industry, and how researchers must adapt to a new world.

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AstraZeneca forges licensing agreement with Redx Pharma

Pharma Times

AZ will pay $17m in early milestone payments for the UK biotech’s fibrotic asset

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