Sat.Jan 23, 2021 - Fri.Jan 29, 2021

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Gene editing: beyond the hype

pharmaphorum

Genome editing is an exciting but still nascent field, and companies in the area face as many obstacles as they do opportunities. Sangamo CEO Sandy Macrae told us how his company is being cautious about the hype and finding ways to be financially viable in an emerging space. ‘Cutting edge’ is, for once, a truly apt description when it comes to gene editing – both because the field is pushing medicine into areas we might never have dreamed possible, and because these technologies involve literall

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eCOA tech helps trials tackle COVID-19 obstacles: IQVIA

Outsourcing Pharma

Two leaders from the clinical technology solutions company discuss how digital tools like eCOAs have been invaluable in facing pandemic-related challenges.

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PMN WEBINAR: Video, Voice, and Virtual: Applying New Digital Technology to Enhance Customer Experience

Pharma Marketing Network

2020 was a year defined by unexpected challenges – and related opportunity – for pharmaceutical marketers. Some Key Discussion Topics Include: What have we learned about how to create connection within this new paradigm? Which recent innovations are poised to become the best practices that will create measurable impact in 2021? Tune in to listen to the Pharma Marketing Network and leading experts from GSK, Otsuka & Bayer as we navigate these trends and discuss what you need to know to

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Women’s Personal Finance.org – Personal BIG Project Alert

That Frugal Pharmacist

What have I been up to… well… partnering with my bestie for the expanded and awesome-r Women’s Personal Finance.org! TLDR: Go to the link above to track our progress and join the email list! My life, it is so cyclical. It feels like I have nothing going on and then a tidal wave of … Women’s Personal Finance.org – Personal BIG Project Alert Read More ».

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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What we’re expecting in 2021, and beyond…

pharmaphorum

From telehealth to digital trials, customer engagement to healthcare data, Healthware Group outlines the key trends that are expected to shake up digital health this year. Well, it goes without saying, COVID-19 has resulted in a rapid adoption of digital technologies across all industries, most notably in healthcare. There are several important aspects to these shifts for pharma, biotech and medical device companies, so what can we expect to see over the next 12 months and beyond?

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Veeva Systems converts to a public benefit corporation

Outsourcing Pharma

While the change signifies the life-sciences solutions firmâs commitment to help customers and patients, day-to-day functions will remain much the same.

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11 Best Robinhood Alternatives To Start Investing Your Money Better

That Frugal Pharmacist

If you are using the Robinhood app for investing, you might be considering switching or just testing out something different. After all, there are many Robinhood alternatives these days, thanks to new fintech companies looking to make it easier for anyone to invest. Yet, with all the investing platforms and apps out there, which are some … 11 Best Robinhood Alternatives To Start Investing Your Money Better Read More ».

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Bad news for Pfizer as blockbuster Xeljanz flunks safety study

pharmaphorum

JAK inhibitor Xeljanz is one of Pfizer’s top-selling drugs, despite a ‘black box’ warning for blood clots and cancers added to its label in 2019. Now, a study designed to prove its safety has achieved the opposite. The post-marketing safety study showed that Xeljanz (tofacitinib) – used to treat rheumatoid arthritis (RA) – was associated with a higher rate of heart attacks and cancer than a TNF inhibitor in patients aged over 50 with underlying cardiovascular risk factors.

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Paradigm4, 54gene collaborate on African clinical data

Outsourcing Pharma

With fewer than 3% of analyzed genomes currently coming from Africans, the companies are looking to increase access to and understanding of patient data.

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Can you take co-codamol with naproxen and diazepam?

Druggist

Today I will review the use of three different drugs, which occasionally are prescribed at the same time or in combination with one another. This post aims to answer the following question: can you take co-codamol with naproxen and diazepam? As a part of the discussion, I will review a licensed use of each drug and reasoning for combination treatment.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Tapp Network and TechSoup Digital Benchmark Report Highlights Opportunities and Challenges

Mission-Driven Marketing Blog

SAN FRANCISCO – January 27, 2021 – The results of the 2020-2021 Nonprofit Digital Marketing Benchmark Report , conducted by TechSoup and Tapp Network, unveil the disruptive effects of the COVID-19 pandemic. The report details how nonprofits are struggling to refocus their outreach efforts to the new digital normal of website automation, social media, online advertising, and content marketing.

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Clinical research in 2021: A new era of collaboration and innovation

pharmaphorum

The clinical research community has been disrupted in a number of ways due to COVID-19 and sparked a spirit of collaboration and innovation. Worldwide Clinical Trial’s Aman Khera gives five predictions of how clinical research could change in 2021. The pandemic has propelled the life science industry toward higher expectations for faster, more responsive and more inclusive drug development.

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Survey reveals patients’ thoughts on trial participation

Outsourcing Pharma

Conducted by SubjectWell, the survey of patients with Type 2 diabetes reveals how ethnicity and other factors play a part in trial participation tendencies.

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Inria and InSilicoTrials partner up on a European project leveraging simulation for cardiac devices and drugs

Pharma Mirror

Inria Sophia Antipolis Méditerranée is leading SimCardioTest, a new EU project funded with 8 million Euros that will provide insight into designing new predictive tools in cardiac pathologies. Among the ten partners, the rising startup InSilicoTrials. The search for new drugs and devices is particularly difficult in the case of cardiovascular disease, which remains the leading cause of death worldwide, with 18 million deaths each year according to World Health Organization estimates.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Co-dydramol vs co-codamol – two related opioids

Druggist

Co-codamol is one of the most popular drugs prescribed in the UK and almost the most popular prescription painkiller. Co-dydramol, on the other hand, is much less popular medicine used for the management of pain. I will highlight the main differences between both drugs and (if possible) review the effectiveness of both drugs as painkillers. Co-dydramol vs co-codamol summary of the post: Difference between co-codamol and co-dydramol (active ingredients).

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RedX Pharma CEO focuses on pipeline that found Lilly’s rising star

pharmaphorum

Back in 2017, the UK biotech RedX Pharma had to sell its prized asset after administrators stepped in to stave off a debt crisis, with Loxo Oncology snapping up the BTK inhibitor for $40 million. That drug, now known as LOXO-305 was one of the stars of the American Society of Haematology (ASH) conference in December, finding its way into Eli Lilly’s pipeline after the big pharma’s $8 billion takeover of Loxo.

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FDA approves injectable treatment for HIV patients

Outsourcing Pharma

The agency has given the thumbs up to ViiVâs once-a-month Cabenuva, the first FDA-approved injectable, complete regimen for adults diagnosed with HIV.

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Inria and InSilicoTrials partner up on a European project leveraging simulation for cardiac devices and drugs

Pharma Mirror

Inria Sophia Antipolis Méditerranée is leading SimCardioTest, a new EU project funded with 8 million Euros that will provide insight into designing new predictive tools in cardiac pathologies. Among the ten partners, the rising startup InSilicoTrials. The search for new drugs and devices is particularly difficult in the case of cardiovascular disease, which remains the leading cause of death worldwide, with 18 million deaths each year according to World Health Organization estimates.

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Cheap Caribbean Vacations – The Ultimate Guide

That Frugal Pharmacist

I know, we’re still mid pandemic so cheap Caribbean vacations may not be your top thought right now. It’s really hard to believe this all started about a year ago. I also know that people are starting to get seriously stir crazy. For many, a bucket list vacation is exactly what is in the books … Cheap Caribbean Vacations – The Ultimate Guide Read More ».

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Novartis hails digital strategy as profits hold up during pandemic

pharmaphorum

Novartis has said that its investment in digital technology has helped it to ride out the worst of the pandemic, although sales of some of its newly-launched products have been affected by a fall in prescriptions and hospital visits. The big Swiss pharma still managed to grow sales in Q4 compared with the same period last year, with sales increasing a reported 3% to $12.8 billion and profits growing 2% to just over $3 billion.

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FDA COVID-19 responses and recommendations this week

Outsourcing Pharma

As the COVID-19 vaccines continue the early stages of circulation in the US, the agency keeps an eye on industry actions and offers advice to key players.

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How Different Crimes Can Affect Your Nursing License in Georgia

Pharma Mirror

Navigating your way to a career in the medical field is not easy. You may have spent late nights studying for exams and long hours working in a medical institute. But, you are finally here about to get your nursing license in the state of Georgia. When applying for a nursing license or getting your old one renewed, you might face some trouble if the background check doesn’t show up clean.

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Digital Health Education for Health Professionals: What are the Next Steps?

The Digital Apothecary

I have served as an academic for the past eight years as an assistant and now associate professor of pharmacy practice, and during this time, my primary concern has been getting health professionals into digital health. It goes without saying it has been an uphill battle, and only in the past 12-24 months have I finally seen significant traction, primarily due to the ongoing Covid-19 Pandemic.

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Novavax’s COVID-19 shot effective against UK strain

pharmaphorum

Novavax’s COVID-19 vaccine could be added to the UK’s growing arsenal of shots against the disease after it showed 89.3% efficacy in a late-stage trial. The shot is the first to show efficacy against the new variant found in the UK which accounted for around half of cases in the phase 3 study. Efficacy against the original COVID-19 strain was calculated at around 95.6%, falling to to around 85.6% against the UK variant strain, based on a post-hoc analysis.

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Radiopharmaceuticals attract increasing interest: SpectronRx

Outsourcing Pharma

While the field is decades old, according to one specialist, more and more industry professionals are noting its diagnostic and treatment potential.

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SSRIs and CYP Enzymes

Med Ed 101

While many who don’t understand pharmacology consider the SSRIs to be interchangeable, significant consequences can result if we don’t pay attention to the risk of drug interactions. When looking at the SSRIs and CYP enzymes, it is critical to remember which ones can interact with other medications. There is also a significant potential that it […].

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PharmaTimes confirms INTCR 2021 virtual finals days

Pharma Times

The 2021 International Clinical Researcher of the Year competition will continue the successes of last year and be conducted virtually.

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Stress not a significant factor in migraine attacks, study finds

pharmaphorum

New findings from a digital study have challenged the belief that stress is a significant factor in triggering migraine attacks. Results came from a study by the digital health firm Curelator and the University of Calgary, who found that only 7.1% of patients had a majority of their attacks associated with increased levels of perceived stress. At the same time 76% of the total number of migraine attacks were associated with either flat or decreasing levels of perceived stress.

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Designated ‘Breakthrough Therapies’ draw support from Calyx

Outsourcing Pharma

The companyâs medical imaging technology and other eClinical solutions reportedly played a part in half of the treatments to receive the FDA designation.

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Constipation Prescribing Cascade

Med Ed 101

At its worst, constipation can be a very serious issue in some patients and at best be a significant nuisance. Here’s a classic example of the constipation prescribing cascade. A 72-year-old female has a history of chronic pain, urinary incontinence, hypertension, and most recently, worsening constipation requiring increasing doses of Senna-S.

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Researchers identify existing drug’s potential for triple negative breast cancer

Pharma Times

Study suggests that palbociclib could be used to treat around a fifth of people with TNBC

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Doctors warn pandemic has pushed lung cancer services back 20 years

pharmaphorum

Governments must act to restore the damage done to lung cancer services during the pandemic in order to reduce further avoidable deaths, according to a report drawn up as part of this week’s World Economic Forum in Davos. The report , Learning Lessons from Across Europe – Prioritising Lung Cancer after COVID-19, highlights how lung cancer progress in diagnosis has been pushed back, with further impact on treatment likely, the longer the pandemic continues.

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COVID-19 tools from Cerba aim to save researchers time

Outsourcing Pharma

The company has released two products designed to help clinical researchers accelerate development of treatments and vaccines for the COVID-19 virus.

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Genetic screening before prescribing could benefit millions, study finds

pharmaphorum

Four million UK patients could benefit annually from genetic testing before being prescribed common medicines, according to new research. Researchers from the University of East Anglia (UEA) in collaboration with Boots UK and Leiden University analysed 2019 NHS dispensing data across the UK. The goal was to see how many patients are started on new prescriptions each year that could be potentially optimised by genetic testing.