Wed.Aug 10, 2022

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Woman of the Week: COTA’s Miruna Sasu

PharmaVoice

Miruna Sasu is on a mission to use real world data to help wipe out cancer. She believes this audacious goal is within reach, and as president and CEO of COTA, she is inspiring her team to create a “path to care” for oncology patients.

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This week’s reading list: All the reasons the Senate-passed drug pricing bill is bad policy

PhRMA

Last weekend, the Senate passed the Inflation Reduction Act which includes dangerous price-setting provisions. The bill now heads to the House for consideration, where it is not too late for them to stand up for patients and medical innovation by opposing the bill.

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AI Opens Door To Improving Patient Experience

PharmExec

The technology is not just about digital enablement anymore.

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Value assessment should include all aspects of value that matter to patients

PhRMA

We need to move toward a more value-driven health care system that centers around patients’ needs. Sound evidence can help guide us toward that, and we’re committed to developing tools to help patients, physicians and others make informed decisions.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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The Silver Lining Of Innovation in Genetic Medicine

PharmExec

Failed efforts do not overshadow field’s progress, resolve.

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4 ways to nail the launch of your cell therapy

PharmaVoice

A consultant’s view on how pharma companies should approach patient experience challenges when rolling out an autologous cell therapy.

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More Trending

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The Price of Innovation: ‘Paying for a Cure’ Remains Costly Proposition

PharmExec

Curative-type therapies offer great hope in further transforming treatments for cancer and other diseases, but addressing the economics of these products—and ultimately the cost-benefit equation—is daunting. What is being done to smooth the path for pricing and reimbursement?

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Study Results Link Menopause Before 40 to Increase in Atrial Fibrillation, Heart Failure

Pharmacy Times

Analysis supports positive lifestyle habits, such as exercising and quitting smoking, investigators say.

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FDA grants Fast-Track status for Relmada’s major depressive disorder therapy

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted Fast-Track designation to Relmada Therapeutics’ REL-1017 as a single agent to treat major depressive disorder (MDD). A new chemical entity and NMDA receptor (NMDAR) channel blocker, REL-1017 acts on hyperactive channels while preserving physiological glutamatergic neurotransmission. Presently, the therapy is being analysed in late-stage studies.

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Study Results Show 86.6% of Individuals With OUD Do Not Receive Life-Saving Medication

Pharmacy Times

Investigators from NYU’s Grossman School of Medicine sound alarm on treatment gap and suggest ways to remove barriers, as opioid overdoses soar to historic levels.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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A World of Opportunity

PharmExec

Marie-France Tschudin, president, innovative medicines international, and chief commercial officer at Novartis, taps into life lessons to help bring therapies to people in novel ways­.

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How Pharmacists Can Help Seniors Age in Place

Pharmacy Times

Pharmacists can play an important role in helping ensure compliance with prescribed medications, which can help seniors maintain their health and quality of life while aging at home.

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Walgreens played ‘substantial’ role in San Francisco opioid crisis, judge finds

The Guardian - Pharmaceutical Industry

The pharmacy chain failed to properly investigate suspicious opioid orders, according to federal ruling Walgreens “substantially contributed” to San Francisco’s opioid epidemic by failing to perform due diligence on prescriptions that flooded into the city for 15 years, a federal judge has found. The city won what local media has called a “ landmark trial ” against Walgreens, with the judge, Charles Breyer, finding that the pharmacy chain had failed to properly investigate suspicious opioid orde

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Clinical Overview: Certain Antihypertensive Drugs Can Lower Risk for New Onset Type 2 Diabetes

Pharmacy Times

Meta-analysis of randomized controlled trials adds to growing evidence around certain antihypertensive drug classes showing promise for primary or secondary prevention of diabetes.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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ADC shrinks brain metastases in HER2+ breast cancer patients

European Pharmaceutical Review

A study published in Nature Medicine demonstrates that active brain metastases in breast cancer patients are partially or even completely regressed by an antibody-drug conjugate (ADC), trastzumab deruxtecan (T-Dxd). The researchers stated that the results are considered ground-breaking in the treatment of brain metastases – and that ADCs open up “a completely new avenue in oncological research and targeted therapy”.

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Rise in Cardiovascular Diseases Could Have Greatest Impact on Ethnicity, Race Minority Groups by 2060

Pharmacy Times

A new study predicts significant increases in cardiovascular issues in the United States, highlighting racial and ethnic inequality of future patients.

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How does irradiation sterilisation impact herbal medicines?

European Pharmaceutical Review

In order to meet microbiological quality standards, herbal medicine pills are often irradiated at the primary package or final product stage. Radiation is chosen over thermal terminal sterilisation to minimise decomposition of crude drug components, volatilisation of essential oils and changes in colour. However, with limited evidence on the impact ionising radiation has on the constituents of such products, researchers set out to investigate whether irradiation impacts drug quality beyond micro

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Environmental Sustainability: An Imperative for the Life Sciences Sector

Pharmaceutical Commerce

Recognizing the sustainability issue is an important step, but the biopharmaceutical sector encompasses a complex set of networks and supply chains, so it is not straightforward to shift towards net zero across all operations.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Back To School Preparedness For Independent Pharmacy Owners

DiversifyRx

Independent pharmacies can play a significant role in helping local communities prepare for back to school. As most parents know, schools are a petri dish for all things contagious. From preschool to high school, students’ and teachers’ immune systems are tested each return of the school year. As a local independent pharmacy owner, you can help prevent and treat common ailments arising from back to school activities.

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Amgen to acquire ChemoCentryx for $3.7bn

European Pharmaceutical Review

Amgen has entered into a definitive agreement to acquire ChemoCentryx Inc., a biopharmaceutical company focused on orally administered therapeutics to treat autoimmune diseases, inflammatory disorders and cancer. Under the agreement, ChemoCentryx will be acquired for $52 per share in cash, for a total enterprise value of approximately $3.7 billion. “The acquisition of ChemoCentryx represents a compelling opportunity for Amgen to add to our decades-long leadership in inflammation and nephro

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Cerevance and Merck partner to detect new Alzheimer’s targets

Pharmaceutical Technology

Cerevance has entered a multi-year strategic research partnership with Merck (MSD outside North America) to discover new targets for Alzheimer’s disease. Under the alliance, the companies will use the Nuclear Enriched Transcript Sort sequencing (NETSseq) technology platform of Cerevance to identify the targets. Furthermore, Cerevance will simultaneously out-license a discovery-stage programme to Merck under the partnership.

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A Step in The Right Direction: Optimization of STOPP/START Recommendations for Pharmacists

Pharmacy Times

Health care professionals need to work closely with patients in understanding polypharmacy and the risk/benefit of pharmacotherapy.

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Pharma’s Training Transformation: COVID Forces Compliance Revamp, Re-education

PharmExec

How one company in particular has adjusted its internal and customer-facing strategies in compliance training amid today’s heightened business-risk climate.

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Daily Medication Pearl: Cangrelor (Kengreal)

Pharmacy Times

Cangrelor (Kengreal) is indicated as an adjunct to percutaneous coronary intervention for reducing the risk of periprocedural myocardial infarction, repeat coronary revascularization, and stent thrombosis.

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Proteomics Keys Promise Of Predictive Medicine

PharmExec

Major stakeholders—including policymakers, public-private interests, and academia—are increasingly embracing the potential of proteomics technology in reshaping diagnostics and patient care.

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HOPA President Addresses, Acknowledges the Achievements of PGY2 Pharmacy Residents This Year

Pharmacy Times

Heidi D. Finnes, PharmD, BCOP, FHOPA, president-elect of Hematology/Oncology Pharmacy Association (HOPA), explains how HOPA can help prepare PGY2 pharmacy residents to obtain and maintain their BCOP certification.

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Catalent to purchase Metrics Contract Services from Mayne Pharma

Pharmaceutical Technology

Catale n t has signed an agreement for the acquisition of full-service specialty Contract Development and Manufacturing Organization (CDMO) Metrics Contract Services for $475m from Mayne Pharma. The takeover of Metrics will bolster the expertise of Catalent in the development of integrated oral solid formulation, production and packaging to aid customers in streamlining and expediting their programmes.

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How Specialty Pharmacies Can Increase Visibility on the Shipment of Critical Patient Medication, Ensure On-Time Delivery

Pharmacy Times

Part 3 in a series outlining 5 crucial steps pharmacies can take to enhance patient engagement and lower operational costs.

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Best Content Ideas for Your Christmas Marketing in Social Media this 2022 – Blog #77

The Social Pharmacist

Campaigns dedicated to Christmas marketing in social media are a fantastic opportunity for eCommerce markets to go all-out on their channels. Apart from merely jumping on the bandwagon by pushing out normal festive greetings, you need the best strategy with your creative posts. Furthermore, many businesses also take the opportunity to showcase holiday spirit, increase their customer engagement to new and old customers and spread the holiday spirit around!

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Measure Stewardship with Expert Input and Consensus-Based Process

PQA

PQA follows a systematic, transparent and consensus-based development?process?to ensure that measures are important, scientifically acceptable, feasible and usable. However, the measurement lifecycle does not end when a measure is endorsed. Previous blogs have?walked through?the?measure conceptualization,?measure specification and measure?testing and measure endorsement phases?

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New Lawsuit Challenges FDA’s Authority to Compel Patent Certifications

The FDA Law Blog

By Sara W. Koblitz — For years , FDA has been wrestling with questions about what patents should be listed in the Orange Book, but, as we have reported, FDA has made little to no progress on addressing those questions. One of those pressing questions that remains unanswered involves the listing of REMS patents in the Orange Book. While FDA asked for Comments in 2020 about whether REMS patents, among others, “are in fact the type of patents that must be submitted” for listing in the Orange Book

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Pharmaceutical Executive, August 2022 Issue (PDF)

PharmExec

Click the title above for a link to open the Pharmaceutical Executive August 2022 issue in an interactive PDF format.

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North America is seeing a hiring boom for AI roles in the pharmaceutical industry

Pharmaceutical Technology

North America extended its dominance for artificial intelligence (AI) hiring among pharmaceutical industry companies in the three months ending June. The number of roles in North America made up 53.2% of total AI jobs - up from 47.6% in the same quarter last year. That was followed by Asia-Pacific, which saw a 0.9 year-on-year percentage point change in AI roles.

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