Tue.Jun 06, 2023

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The Cross-Roads Of Artificial Intelligence & Infectious Diseases Education: Witty Insights From ChatGPT

IDStewardship

In this article, ChatGPT provides witty insights into the cross-roads of artificial intelligence and infectious diseases. Interview with: ChatGPT by OpenAI Interview by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article Posted 7 June 2023 With the exception of the questions in bold, this entire text was written by ChatGPT. The only thing removed from the questions is the instruction “in a witty way” and a character limit was used in each of the questions.

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Pharmacists Will Play Critical Role in Helping Patients Navigate Digital Therapeutics

Drug Topics

With the rise of prescription digital therapeutics, pharmacists will need to prepare to manage the new paradigms of care.

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How Pharmacists Can Use Artificial Intelligence To Advance Their Practice: Insights From ChatGPT

IDStewardship

In this article, ChatGPT weighs in on how pharmacists can use artificial intelligence. Interview with: ChatGPT by OpenAI Interview by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article Posted 7 June 2023 With the exception of the questions in bold, this entire text was written by ChatGPT. Welcome, fellow curious minds, to a captivating interview that promises to open doors to a world where artificial intelligence (AI) and the pharmaceutical profession unite in a delightful dance.

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Breaking: Merck Files Lawsuit to Halt Medicare Drug Price Negotiations

Drug Topics

According to a spokesperson, the company is prepared to take the lawsuit to the Supreme Court.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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The latest generative AI efforts in healthcare: Carbon Health, Tempus launch tools for docs

Fierce Healthcare

Advancements around large language models and generative AI in healthcare are ramping up quickly and it's challenging to keep up with the evolving news. | Carbon Health debuted hands-free charting — an AI-enabled notes assistant — in its proprietary EHR across each of its clinics and providers while Tempus rolled out an AI-enabled clinical assistant for oncologists.

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Should We Welcome AI, Fear It, Or Both?

Drug Topics

A research article outlines the future of artificial intelligence in health care.

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More Trending

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Opinion: When should hospitals require masks?

STAT

Is the pandemic over ? On the one hand, Covid-19 is clearly still with us. In the U.S., over the past month there was a weekly average of 557 deaths , though the numbers are dropping sharply, from 849 four weeks ago to 208 last week. On the other, for those who are not vulnerable or immune compromised, most facets of life have returned to normal, thanks to high levels of immunity from vaccines, boosters, and past infections.

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Obstructive Sleep Apnea May Have Significant Impact on Cognitive Decline in Middle-Aged Individuals

Pharmacy Times

Recent debates have surrounded whether cognitive deficits, specifically in middle-aged patients, may be driven by cardiovascular and metabolic comorbidities instead of distinct obstructive sleep apnea processes.

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Physician compensation is rising but not keeping pace with inflation, MGMA survey finds

Fierce Healthcare

Despite physician and advanced practice provider productivity continuing its post-pandemic recovery, compensation gains are being outstripped by the most severe inflationary growth in decades, acco | Despite physician and advanced practice provider productivity continuing its post-pandemic recovery, compensation gains are being outstripped by the most severe inflationary growth in decades, according to a new report.

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Dual Bispecific Combination Study Shows 96% Overall Response Rate in Relapsed/Refractory Multiple Myeloma

Pharmacy Times

Findings highlight the potential efficacy of combining 2 novel bispecific therapies, teclistamab-cqyv and talquetamab, which target distinct antigens on myeloma cells.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Pharmacy Technology: How to Implement the Right Tools Now

Drug Topics

If your pharmacy is among the 40% of those who admit to not using technology to the fullest extent, this is for you: Here are 5 things to consider to find the right tools that savvy customers want.

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Expert: KEYNOTE-716 Could be a "Game-Changer" for Patients with Stage 2 Melanoma At High Risk of Recurrence

Pharmacy Times

Until this study, adjuvant immunotherapy was standard of care for stage 3B melanoma but not stage 2, which has relatively similar survival rates and risk of recurrence.

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FDA Clears Prostate Cancer Treatment Lynparza

Drug Topics

The combination of Lynparza and abiraterone reduced the risk of disease progression or death by 76% vs. abiraterone alone in patients with BRCA-mutated metastatic castration-resistant prostate cancer.

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Trastuzumab Deruxtecan Demonstrates Responses Across Advanced Solid Tumors With HER2 Expression

Pharmacy Times

Trial results support 5.4 mg/kg of trastuzumab deruxtecan as the optimal dose in individuals with HER2+ metastatic colorectal cancer.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Appeals court weighs lifting freeze on ACA preventive care ruling

Fierce Healthcare

A federal appeals court held a brief hearing Tuesday afternoon to hear from attorneys on both sides as it decides whether to lift a nationwide freeze on a lower court's ruling that struck down prev | A federal appeals court held a brief hearing Tuesday afternoon to hear from attorneys on both sides as it decides whether to lift a nationwide freeze on a lower court's ruling that struck down preventive care protections in the Affordable Care Act.

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Academia’s postdoc system is teetering, imperiling efforts to diversify life sciences

STAT

For young life scientists hoping to land a prestigious faculty job in academia, postdoctoral research is practically a requirement. But it’s not a path equally open to everyone. Freshly minted life science Ph.D. graduates who have started families or have big loans, or are Black or female, say they plan to pursue postdoc positions at lower rates than their peers, according to a STAT analysis that includes previously unreported data from the National Center for Science and Engineering Stat

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Morning RX: June 6, 2023

Drug Topics

Merck sues the federal government, the FDA will allow cancer drug imports from China, and a drug from GSK shows promise for endometrial cancer treatment.

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Alkeus raises funds to launch Stargardt disease therapy gildeuretinol

Pharmaceutical Technology

Alkeus Pharmaceuticals has raised $150m in Series B financing to support the registration and launch of gildeuretinol (ALK-001) to treat Stargardt disease, a genetic cause of blindness in children and young adults. Led by Bain Capital Life Sciences, the financing round has also seen participation from Sofinnova Investments, TCGX and Wellington Management.

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Merck challenges HHS on Medicare drug price negotiations, alleging violations of the Constitution

Fierce Pharma

The pharma industry has voiced loud complaints about the Biden administration's Inflation Reduction Act, specifically focusing on a clause that will allow Medicare to negotiate the prices of top-se | The pharma industry has voiced loud complaints about the Biden administration's Inflation Reduction Act, specifically focusing on a clause that will allow Medicare to negotiate the prices of top-selling pharmaceuticals.

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FDA Approves New Indication for Letermovir for Prevention of Cytomegalovirus in Adult Kidney Transplant Recipients

Pharmacy Times

The proportion of participants with cytomegalovirus disease was 10% with letermovir and 12% with valganciclovir.

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Eisai hit with ransomware attack, launches investigation into possible data leaks

Fierce Pharma

Eisai is the latest drugmaker to be hit with a ransomware attack. | Eisai was the victim of a ransomware attack late Saturday night and is now working on response efforts, including the creation of a company-wide task force.

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Federal judge blocks Florida ban on gender transition care, suggests law is unconstitutional

Fierce Healthcare

High-profile legislation restricting gender transition care recently enacted in Florida was halted this week by a federal judge concerned of immediate harm to patients and seemingly unconvinced tha | The district court judge's scathing order characterized restrictions on gender transition care as political and a likely violation of the Fourteenth Amendment's Equal Protection Clause.

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Novo Holdings, Gurnet Point team up to buy antibiotics maker Paratek for $462M

Fierce Pharma

Novo Holdings and Gurnet Point have added antibiotics maker Paratek Pharma to their fold in a biopharma M&A deal worth approximately $462 million. | Paratek's key selling point is its antibiotic, Nuzyra, which was expected to garner $500 million in peak sales at the time of its 2018 approval.

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ATMPs from Proof of Concept to Commercial Manufacturing

ISPE

ATMPs from Proof of Concept to Commercial Manufacturing Trudy Patterson Tue, 06/06/2023 - 11:53 iSpeak Blog iSpeak ATMPs from Proof of Concept to Commercial Manufacturing Nikhe Bartelt Richard Denk 6 June 2023 Welcome fellow ISPE Bio Manufacturing members, sponsors, industry professionals, or those interested in the manufacturing of Cell and Gene Therapies!

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‘Tantamount to extortion:’ Merck sues U.S. government over Medicare negotiation program

STAT

WASHINGTON — Merck on Tuesday sued to stop the federal government from implementing a new Medicare drug price negotiation program. Merck called the negotiation process that Democrats designed in a law last August “a sham,” arguing that the federal government “dictates” prices.

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How long does it take Viagra to kick in?

The Checkup by Singlecare

Since its FDA approval in 1998, Viagra (sildenafil citrate) has become a well-known prescription medication for treating erectile dysfunction (ED), affecting about 30 million men in the U.S. alone. But to ensure it works, it’s not as simple as popping the little blue pill. For best results, timing may be everything. Read on to learn when to take Viagra, how long it takes Viagra to work, and more need-to-know tips.

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Opinion: Four communication lessons we learned the hard way during the pandemic

STAT

Now that the Covid-19 public health emergency has ended, it’s awfully tempting to put the pandemic firmly behind us. But now is the time to look at what we have learned so that our public health communication can be more clear, consistent, and effective from now on. One thing that we haven’t talked about enough is the victories.

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FDA sets the stage for adcomm on Sanofi, AZ's RSV prospect later this week

Fierce Pharma

As GSK and Pfizer look to roll out their adult respiratory syncytial virus (RSV) vaccines later this year, Sanofi and AstraZeneca hope to join them on the market with an antibody designed to protec | As GSK and Pfizer look to roll out their adult RSV vaccines later this year, Sanofi and AstraZeneca hope to join them on the market with an antibody designed to protect infants.

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This venture capitalist sees plenty of promise in AI in healthcare. But challenges are ahead, too

Fierce Healthcare

“Garbage in, garbage out.” So goes the adage about computing that argues the results rendered by the “thinking” machines will be flawed if the information fed into the devices proves to be erroneou | Dennis L. McWilliams, a partner at Santé Ventures, says experts are still trying to figure out exactly how AI will fit into the healthcare system and who will pay for it.

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Immunotherapy-Induced Pneumonitis Common in Patients With NSCLC

Drug Topics

Knowledge gaps exist around the timing of pneumonitis onset in patients treated with checkpoint inhibitors.

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Oragenics secures CQDM funding for Covid-19 vaccine antigen development

Pharmaceutical Technology

Oragenics has secured funding from the Canadian bioresearch consortium CQDM to develop a variant-agnostic protein antigen for use in its Covid-19 intranasal vaccine. SynergiQC, the Quebec-based funding programme created by CQDM, has awarded the funding. The project is a partnership with Inspirevax and the National Research Council of Canada (NRC). In March 2023, Oragenics and Inspirevax entered an exclusive global licence deal to develop the former’s lead intranasal Covid-19 vaccine candidate, N

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Alkermes, after arbitration win over J&J, jacks up revenue forecast by $425M

Fierce Pharma

Alkermes has bumped | Alkermes has bumped up its revenue forecast for 2023 by $425 million after winning a final award in its arbitration battle with Johnson & Johnson over the licensing of its NanoCrystal technology. The final award came last week from the arbitral tribunal.

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STChealth establishes electronic vaccine reporting connections for pharmacies in North Carolina

Drug Store News

Pharmacies and healthcare providers can establish electronic connections to the NCIR to improve patient outcomes and streamline reporting of immunizations.

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Patient recruitment - what the problems are and how Greenphire is tackling them

Outsourcing Pharma

Jim Murphy is Greenphire's CEO and leads the company's strategy and he says he is committed to fostering a culture of growth, innovation, excellence and employee satisfaction. Under his leadership, the company has expanded exponentially - in product depth, client adoption and geographic coverage.

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