Tue.Jun 06, 2023

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The Cross-Roads Of Artificial Intelligence & Infectious Diseases Education: Witty Insights From ChatGPT

IDStewardship

In this article, ChatGPT provides witty insights into the cross-roads of artificial intelligence and infectious diseases. Interview with: ChatGPT by OpenAI Interview by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article Posted 7 June 2023 With the exception of the questions in bold, this entire text was written by ChatGPT. The only thing removed from the questions is the instruction “in a witty way” and a character limit was used in each of the questions.

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Pharmacists Will Play Critical Role in Helping Patients Navigate Digital Therapeutics

Drug Topics

With the rise of prescription digital therapeutics, pharmacists will need to prepare to manage the new paradigms of care.

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How Pharmacists Can Use Artificial Intelligence To Advance Their Practice: Insights From ChatGPT

IDStewardship

In this article, ChatGPT weighs in on how pharmacists can use artificial intelligence. Interview with: ChatGPT by OpenAI Interview by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article Posted 7 June 2023 With the exception of the questions in bold, this entire text was written by ChatGPT. Welcome, fellow curious minds, to a captivating interview that promises to open doors to a world where artificial intelligence (AI) and the pharmaceutical profession unite in a delightful dance.

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Breaking: Merck Files Lawsuit to Halt Medicare Drug Price Negotiations

Drug Topics

According to a spokesperson, the company is prepared to take the lawsuit to the Supreme Court.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Opinion: When should hospitals require masks?

STAT

Is the pandemic over ? On the one hand, Covid-19 is clearly still with us. In the U.S., over the past month there was a weekly average of 557 deaths , though the numbers are dropping sharply, from 849 four weeks ago to 208 last week. On the other, for those who are not vulnerable or immune compromised, most facets of life have returned to normal, thanks to high levels of immunity from vaccines, boosters, and past infections.

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Should We Welcome AI, Fear It, Or Both?

Drug Topics

A research article outlines the future of artificial intelligence in health care.

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More Trending

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Obstructive Sleep Apnea May Have Significant Impact on Cognitive Decline in Middle-Aged Individuals

Pharmacy Times

Recent debates have surrounded whether cognitive deficits, specifically in middle-aged patients, may be driven by cardiovascular and metabolic comorbidities instead of distinct obstructive sleep apnea processes.

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Mayo Clinic, Google Cloud partner on generative AI to power enterprise search

Fierce Healthcare

Mayo Clinic is collaborating with Google Cloud to supercharge search tools with generative AI. | Mayo Clinic is collaborating with Google Cloud to supercharge search tools with generative AI. The health system aims to use the buzzy new technology to make it easier for doctors to get access to relevant medical notes, research papers or clinical guidelines.

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Dual Bispecific Combination Study Shows 96% Overall Response Rate in Relapsed/Refractory Multiple Myeloma

Pharmacy Times

Findings highlight the potential efficacy of combining 2 novel bispecific therapies, teclistamab-cqyv and talquetamab, which target distinct antigens on myeloma cells.

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Physician compensation is rising but not keeping pace with inflation, MGMA survey finds

Fierce Healthcare

Despite physician and advanced practice provider productivity continuing its post-pandemic recovery, compensation gains are being outstripped by the most severe inflationary growth in decades, acco | Despite physician and advanced practice provider productivity continuing its post-pandemic recovery, compensation gains are being outstripped by the most severe inflationary growth in decades, according to a new report.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Academia’s postdoc system is teetering, imperiling efforts to diversify life sciences

STAT

For young life scientists hoping to land a prestigious faculty job in academia, postdoctoral research is practically a requirement. But it’s not a path equally open to everyone. Freshly minted life science Ph.D. graduates who have started families or have big loans, or are Black or female, say they plan to pursue postdoc positions at lower rates than their peers, according to a STAT analysis that includes previously unreported data from the National Center for Science and Engineering Stat

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Pharmacy Technology: How to Implement the Right Tools Now

Drug Topics

If your pharmacy is among the 40% of those who admit to not using technology to the fullest extent, this is for you: Here are 5 things to consider to find the right tools that savvy customers want.

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Appeals court weighs lifting freeze on ACA preventive care ruling

Fierce Healthcare

A federal appeals court held a brief hearing Tuesday afternoon to hear from attorneys on both sides as it decides whether to lift a nationwide freeze on a lower court's ruling that struck down prev | A federal appeals court held a brief hearing Tuesday afternoon to hear from attorneys on both sides as it decides whether to lift a nationwide freeze on a lower court's ruling that struck down preventive care protections in the Affordable Care Act.

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FDA Clears Prostate Cancer Treatment Lynparza

Drug Topics

The combination of Lynparza and abiraterone reduced the risk of disease progression or death by 76% vs. abiraterone alone in patients with BRCA-mutated metastatic castration-resistant prostate cancer.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Expert: KEYNOTE-716 Could be a "Game-Changer" for Patients with Stage 2 Melanoma At High Risk of Recurrence

Pharmacy Times

Until this study, adjuvant immunotherapy was standard of care for stage 3B melanoma but not stage 2, which has relatively similar survival rates and risk of recurrence.

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Opinion: Four communication lessons we learned the hard way during the pandemic

STAT

Now that the Covid-19 public health emergency has ended, it’s awfully tempting to put the pandemic firmly behind us. But now is the time to look at what we have learned so that our public health communication can be more clear, consistent, and effective from now on. One thing that we haven’t talked about enough is the victories.

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Trastuzumab Deruxtecan Demonstrates Responses Across Advanced Solid Tumors With HER2 Expression

Pharmacy Times

Trial results support 5.4 mg/kg of trastuzumab deruxtecan as the optimal dose in individuals with HER2+ metastatic colorectal cancer.

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Morning RX: June 6, 2023

Drug Topics

Merck sues the federal government, the FDA will allow cancer drug imports from China, and a drug from GSK shows promise for endometrial cancer treatment.

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Alkeus raises funds to launch Stargardt disease therapy gildeuretinol

Pharmaceutical Technology

Alkeus Pharmaceuticals has raised $150m in Series B financing to support the registration and launch of gildeuretinol (ALK-001) to treat Stargardt disease, a genetic cause of blindness in children and young adults. Led by Bain Capital Life Sciences, the financing round has also seen participation from Sofinnova Investments, TCGX and Wellington Management.

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STAT+: Biogen board and C-suite are in step as they eye M&A opportunities, new CEO says

STAT

BOSTON — As Biogen’s new CEO Chris Viehbacher pores over Biogen’s books and scouts out M&A deals, he may have one advantage his predecessor didn’t: a good relationship with his board of directors. Investors have expressed hope over the last several years that Biogen would make more acquisition deals, but it’s been a point of contention within the company.

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Eisai hit with ransomware attack, launches investigation into possible data leaks

Fierce Pharma

Eisai is the latest drugmaker to be hit with a ransomware attack. | Eisai was the victim of a ransomware attack late Saturday night and is now working on response efforts, including the creation of a company-wide task force.

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STAT+: Novocure’s electric fields device prolongs survival in lung cancer, but doubts remain

STAT

CHICAGO — A medical device made by Novocure that creates electric fields in the lungs via wearable skin patches extended the survival of patients with lung cancer in a clinical trial, researchers reported Tuesday. The findings could lead to a new approval for the device, called Optune, beyond its current marketing clearance to treat a type of brain cancer.

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FDA Approves New Indication for Letermovir for Prevention of Cytomegalovirus in Adult Kidney Transplant Recipients

Pharmacy Times

The proportion of participants with cytomegalovirus disease was 10% with letermovir and 12% with valganciclovir.

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Watch: Why do we get seasonal allergies?

STAT

There’s nothing better than a beautiful spring day after a long, cold winter. But there’s nothing worse than having that day ruined by the sneezing, sniffling, and itching that come with seasonal allergies. Scientists don’t actually completely understand why we get seasonal allergies. The best estimation is that they’re an immune response to toxins in the natural environment that pollen also happens to trigger.

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Novo Holdings, Gurnet Point team up to buy antibiotics maker Paratek for $462M

Fierce Pharma

Novo Holdings and Gurnet Point have added antibiotics maker Paratek Pharma to their fold in a biopharma M&A deal worth approximately $462 million. | Paratek's key selling point is its antibiotic, Nuzyra, which was expected to garner $500 million in peak sales at the time of its 2018 approval.

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STAT+: FDA will allow troubled chemotherapy maker to resume distribution of cancer drugs in short supply

STAT

After finding a “cascade of failures” at a manufacturing plant run by a key chemotherapy supplier, the Food and Drug Administration will not allow the company to resume distribution in the U.S. beyond some   cancer medicines that are in short supply. The agency issued the import alert last week to Intas Pharmaceuticals, which is based in India, after its inspectors found a litany of quality-control problems that were detailed in a 36-page inspection report in December.

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Federal judge blocks Florida ban on gender transition care, suggests law is unconstitutional

Fierce Healthcare

High-profile legislation restricting gender transition care recently enacted in Florida was halted this week by a federal judge concerned of immediate harm to patients and seemingly unconvinced tha | The district court judge's scathing order characterized restrictions on gender transition care as political and a likely violation of the Fourteenth Amendment's Equal Protection Clause.

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STAT+: More than 200 FDA staffers have retired in less than a year

STAT

WASHINGTON — More than 230 people have retired from the Food and Drug Administration since Oct. 1, Chief of Staff Julie Tierney said Monday. It’s part of a bigger wave of exits: In total, 634 employees have left the agency, which has a staff of about 18,000 people. There are about 2,000 vacancies at the FDA, which is a normal level at an agency that has for a long time struggled to hire and keep employees who can make bigger salaries in the private sector.

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This venture capitalist sees plenty of promise in AI in healthcare. But challenges are ahead, too

Fierce Healthcare

“Garbage in, garbage out.” So goes the adage about computing that argues the results rendered by the “thinking” machines will be flawed if the information fed into the devices proves to be erroneou | Dennis L. McWilliams, a partner at Santé Ventures, says experts are still trying to figure out exactly how AI will fit into the healthcare system and who will pay for it.

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STAT+: Biotech’s trade secrets face growing threat from foreign influences, science leaders warn

STAT

BOSTON — While most panel discussions at the Biotechnology Innovation Organization’s international convention tend to be heavy on jargon and light on urgency, a conversation on Tuesday about the growing threat foreign influences pose to the industry’s trade secrets could not have been more direct. “It’s really easy to wake up one morning and realize that you might actually be an industrial spy for a foreign government,” said Allen Phelps, CEO of IPTalons

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FDA sets the stage for adcomm on Sanofi, AZ's RSV prospect later this week

Fierce Pharma

As GSK and Pfizer look to roll out their adult respiratory syncytial virus (RSV) vaccines later this year, Sanofi and AstraZeneca hope to join them on the market with an antibody designed to protec | As GSK and Pfizer look to roll out their adult RSV vaccines later this year, Sanofi and AstraZeneca hope to join them on the market with an antibody designed to protect infants.

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How a digital biomarker study failed, Apple’s health updates, and Carbon’s AI-driven EHR

STAT

You’re reading the web edition of STAT Health Tech, our guide to how tech is transforming the life sciences.  Sign up to get this newsletter  delivered in your inbox every Tuesday and Thursday.

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Immunotherapy-Induced Pneumonitis Common in Patients With NSCLC

Drug Topics

Knowledge gaps exist around the timing of pneumonitis onset in patients treated with checkpoint inhibitors.

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STAT+: Pharmalittle: Merck sues U.S. to halt Medicare drug-price negotiation; FDA oncology head wants advisory panels to keep voting on new drugs

STAT

Rise and shine, everyone, another busy day is on the way. We can tell by the steady stream of vehicles passing under our window and the outsized number of emails arriving in our inbox. But busy is generally a good thing, yes? So to help things move along as smoothly as possible, we are firing up the trusty coffee kettle and brewing another cup of stimulation.

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