IDStewardship

JUNE 6, 2023

In this article, ChatGPT provides witty insights into the cross-roads of artificial intelligence and infectious diseases. Interview with: ChatGPT by OpenAI Interview by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article Posted 7 June 2023 With the exception of the questions in bold, this entire text was written by ChatGPT. The only thing removed from the questions is the instruction “in a witty way” and a character limit was used in each of the questions.

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Immunization 246

Drug Topics

JUNE 6, 2023

With the rise of prescription digital therapeutics, pharmacists will need to prepare to manage the new paradigms of care.

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IDStewardship

JUNE 6, 2023

In this article, ChatGPT weighs in on how pharmacists can use artificial intelligence. Interview with: ChatGPT by OpenAI Interview by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article Posted 7 June 2023 With the exception of the questions in bold, this entire text was written by ChatGPT. Welcome, fellow curious minds, to a captivating interview that promises to open doors to a world where artificial intelligence (AI) and the pharmaceutical profession unite in a delightful dance.

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Drug Topics

JUNE 6, 2023

According to a spokesperson, the company is prepared to take the lawsuit to the Supreme Court.

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Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

STAT

JUNE 6, 2023

Is the pandemic over ? On the one hand, Covid-19 is clearly still with us. In the U.S., over the past month there was a weekly average of 557 deaths , though the numbers are dropping sharply, from 849 four weeks ago to 208 last week. On the other, for those who are not vulnerable or immune compromised, most facets of life have returned to normal, thanks to high levels of immunity from vaccines, boosters, and past infections.

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Hospitals Immunization Vaccines 142

Drug Topics

JUNE 6, 2023

A research article outlines the future of artificial intelligence in health care.

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Pharmacy Times

JUNE 6, 2023

Recent debates have surrounded whether cognitive deficits, specifically in middle-aged patients, may be driven by cardiovascular and metabolic comorbidities instead of distinct obstructive sleep apnea processes.

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Fierce Healthcare

JUNE 6, 2023

Mayo Clinic is collaborating with Google Cloud to supercharge search tools with generative AI. | Mayo Clinic is collaborating with Google Cloud to supercharge search tools with generative AI. The health system aims to use the buzzy new technology to make it easier for doctors to get access to relevant medical notes, research papers or clinical guidelines.

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Mayo Clinic 133

STAT

JUNE 6, 2023

For young life scientists hoping to land a prestigious faculty job in academia, postdoctoral research is practically a requirement. But it’s not a path equally open to everyone. Freshly minted life science Ph.D. graduates who have started families or have big loans, or are Black or female, say they plan to pursue postdoc positions at lower rates than their peers, according to a STAT analysis that includes previously unreported data from the National Center for Science and Engineering Stat

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Fierce Healthcare

JUNE 6, 2023

Despite physician and advanced practice provider productivity continuing its post-pandemic recovery, compensation gains are being outstripped by the most severe inflationary growth in decades, acco | Despite physician and advanced practice provider productivity continuing its post-pandemic recovery, compensation gains are being outstripped by the most severe inflationary growth in decades, according to a new report.

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Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

FDA

Pharmacy Times

JUNE 6, 2023

Findings highlight the potential efficacy of combining 2 novel bispecific therapies, teclistamab-cqyv and talquetamab, which target distinct antigens on myeloma cells.

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Drug Topics

JUNE 6, 2023

If your pharmacy is among the 40% of those who admit to not using technology to the fullest extent, this is for you: Here are 5 things to consider to find the right tools that savvy customers want.

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Pharmacy Times

JUNE 6, 2023

Until this study, adjuvant immunotherapy was standard of care for stage 3B melanoma but not stage 2, which has relatively similar survival rates and risk of recurrence.

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Drug Topics

JUNE 6, 2023

The combination of Lynparza and abiraterone reduced the risk of disease progression or death by 76% vs. abiraterone alone in patients with BRCA-mutated metastatic castration-resistant prostate cancer.

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FDA 98

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Pharmacy Times

JUNE 6, 2023

Trial results support 5.4 mg/kg of trastuzumab deruxtecan as the optimal dose in individuals with HER2+ metastatic colorectal cancer.

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Fierce Healthcare

JUNE 6, 2023

A federal appeals court held a brief hearing Tuesday afternoon to hear from attorneys on both sides as it decides whether to lift a nationwide freeze on a lower court's ruling that struck down prev | A federal appeals court held a brief hearing Tuesday afternoon to hear from attorneys on both sides as it decides whether to lift a nationwide freeze on a lower court's ruling that struck down preventive care protections in the Affordable Care Act.

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STAT

JUNE 6, 2023

Now that the Covid-19 public health emergency has ended, it’s awfully tempting to put the pandemic firmly behind us. But now is the time to look at what we have learned so that our public health communication can be more clear, consistent, and effective from now on. One thing that we haven’t talked about enough is the victories.

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Communication 114

Drug Topics

JUNE 6, 2023

Merck sues the federal government, the FDA will allow cancer drug imports from China, and a drug from GSK shows promise for endometrial cancer treatment.

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FDA 98

Pharmaceutical Technology

JUNE 6, 2023

Alkeus Pharmaceuticals has raised $150m in Series B financing to support the registration and launch of gildeuretinol (ALK-001) to treat Stargardt disease, a genetic cause of blindness in children and young adults. Led by Bain Capital Life Sciences, the financing round has also seen participation from Sofinnova Investments, TCGX and Wellington Management.

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Fierce Pharma

JUNE 6, 2023

Eisai is the latest drugmaker to be hit with a ransomware attack. | Eisai was the victim of a ransomware attack late Saturday night and is now working on response efforts, including the creation of a company-wide task force.

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STAT

JUNE 6, 2023

BOSTON — As Biogen’s new CEO Chris Viehbacher pores over Biogen’s books and scouts out M&A deals, he may have one advantage his predecessor didn’t: a good relationship with his board of directors. Investors have expressed hope over the last several years that Biogen would make more acquisition deals, but it’s been a point of contention within the company.

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Fierce Pharma

JUNE 6, 2023

Alkermes has bumped | Alkermes has bumped up its revenue forecast for 2023 by $425 million after winning a final award in its arbitration battle with Johnson & Johnson over the licensing of its NanoCrystal technology. The final award came last week from the arbitral tribunal.

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Pharmacy Times

JUNE 6, 2023

The proportion of participants with cytomegalovirus disease was 10% with letermovir and 12% with valganciclovir.

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FDA 122

Fierce Pharma

JUNE 6, 2023

Novo Holdings and Gurnet Point have added antibiotics maker Paratek Pharma to their fold in a biopharma M&A deal worth approximately $462 million. | Paratek's key selling point is its antibiotic, Nuzyra, which was expected to garner $500 million in peak sales at the time of its 2018 approval.

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STAT

JUNE 6, 2023

There’s nothing better than a beautiful spring day after a long, cold winter. But there’s nothing worse than having that day ruined by the sneezing, sniffling, and itching that come with seasonal allergies. Scientists don’t actually completely understand why we get seasonal allergies. The best estimation is that they’re an immune response to toxins in the natural environment that pollen also happens to trigger.

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Immunization 100

Fierce Pharma

JUNE 6, 2023

As GSK and Pfizer look to roll out their adult respiratory syncytial virus (RSV) vaccines later this year, Sanofi and AstraZeneca hope to join them on the market with an antibody designed to protec | As GSK and Pfizer look to roll out their adult RSV vaccines later this year, Sanofi and AstraZeneca hope to join them on the market with an antibody designed to protect infants.

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STAT

JUNE 6, 2023

After finding a “cascade of failures” at a manufacturing plant run by a key chemotherapy supplier, the Food and Drug Administration will not allow the company to resume distribution in the U.S. beyond some   cancer medicines that are in short supply. The agency issued the import alert last week to Intas Pharmaceuticals, which is based in India, after its inspectors found a litany of quality-control problems that were detailed in a 36-page inspection report in December.

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Chemotherapy FDA Documentation 99

Fierce Healthcare

JUNE 6, 2023

High-profile legislation restricting gender transition care recently enacted in Florida was halted this week by a federal judge concerned of immediate harm to patients and seemingly unconvinced tha | The district court judge's scathing order characterized restrictions on gender transition care as political and a likely violation of the Fourteenth Amendment's Equal Protection Clause.

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European Pharmaceutical Review

JUNE 6, 2023

A new global Minimized Risk of Antimicrobial Resistance (AMR) certification has been launched to promote and demonstrate responsible antibiotic manufacturing in the global pharmaceutical supply chain. BSI, a UK standards body, developed the new certification to the Antibiotic Manufacturing Standard published in June 2022. Standard for antibiotic manufacturing to help combat AMR … Following this “ground-breaking standard” stated Courtney Soulsby, BSI Global Director for Healthcare Sustainab

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Pharmaceutical Companies Pharmaceutical Companies 98

ISPE

JUNE 6, 2023

ATMPs from Proof of Concept to Commercial Manufacturing Trudy Patterson Tue, 06/06/2023 - 11:53 iSpeak Blog iSpeak ATMPs from Proof of Concept to Commercial Manufacturing Nikhe Bartelt Richard Denk 6 June 2023 Welcome fellow ISPE Bio Manufacturing members, sponsors, industry professionals, or those interested in the manufacturing of Cell and Gene Therapies!

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Hospitals Vaccines FDA 98

European Pharmaceutical Review

JUNE 6, 2023

Eighty-eight percent of lung cancer patients were alive after five years after being treated with AstraZeneca’s small molecule treatment TAGRISSO ® (osimertinib) in a Phase III trial. This was compared to 78 percent of patients on placebo in the overall trial population. The adjuvant treatment was given to early-stage (IB, II and IIIA) epidermal growth factor receptor-mutated (EGFRm) non-small cell lung cancer ( NSCLC ) patients following a complete tumour resection with curative intent.

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STAT

JUNE 6, 2023

CHICAGO — A medical device made by Novocure that creates electric fields in the lungs via wearable skin patches extended the survival of patients with lung cancer in a clinical trial, researchers reported Tuesday. The findings could lead to a new approval for the device, called Optune, beyond its current marketing clearance to treat a type of brain cancer.

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Chemotherapy Immunization 97

The Checkup by Singlecare

JUNE 6, 2023

Since its FDA approval in 1998, Viagra (sildenafil citrate) has become a well-known prescription medication for treating erectile dysfunction (ED), affecting about 30 million men in the U.S. alone. But to ensure it works, it’s not as simple as popping the little blue pill. For best results, timing may be everything. Read on to learn when to take Viagra, how long it takes Viagra to work, and more need-to-know tips.

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STAT

JUNE 6, 2023

WASHINGTON — More than 230 people have retired from the Food and Drug Administration since Oct. 1, Chief of Staff Julie Tierney said Monday. It’s part of a bigger wave of exits: In total, 634 employees have left the agency, which has a staff of about 18,000 people. There are about 2,000 vacancies at the FDA, which is a normal level at an agency that has for a long time struggled to hire and keep employees who can make bigger salaries in the private sector.

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FDA 97