Thu.Dec 08, 2022

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In their own words: Financial barriers exacerbate access challenges for insured Americans

PhRMA

A survey of more than 5,000 Americans conducted with Ipsos found that 30% of insured Americans say they face a financial barrier to care, such as unaffordable out-of-pocket costs or a lack of savings to pay for emergency or unforeseen expenses.

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Cost Plus Drugs Making Deals with Payers

Drug Topics

Mark Cuban’s Cost Plus Drugs business has entered into agreements with Capital Blue Cross and Rightway.

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Trending Sources

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Sparking conversations — and careers — at the 2nd annual Pathways to Success Summit

PhRMA

On September 28-29, 2022, PhRMA hosted the second annual Pathways to Success: Virtual Graduate Summit and Career Expo. This event provided a unique opportunity for students and faculty from diverse backgrounds to engage with biopharma recruiters and employees. For the second year in a row, our attendees discovered career opportunities and built connections in the biopharma industry, all while learning valuable knowledge from mentors and thought leaders.

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Opinion: If you think health care is dysfunctional now, just wait until after January 1

STAT

Doctors across the country, especially those in primary care, have been up in arms about Medicare’s proposed cuts in reimbursement that are scheduled to go into effect on January 1. They are concerned — rightfully so — that these cuts will be ruinous to their practices and compromise the care they can provide to their patients. As an emergency physician, I worry about the cuts for a different reason: emergency departments might soon be filled with more and more people who ca

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Study Finds Recommendations for Lowering Heart Disease Risk Vary by Gender

Pharmacy Times

Study finds men are more likely to be prescribed statins and women are more likely to be advised to make lifestyle changes to lessen the risk of cardiovascular disease.

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Kite and Daiichi Sankyo update cell therapy licensing agreement

Pharmaceutical Technology

Kite Pharma and Daiichi Sankyo have updated a partnership agreement signed in 2017 for the former’s CAR T-cell therapy, Yescarta (axicabtagene ciloleucel). Under the prior deal, Daiichi Sankyo acquired exclusive rights for the development, manufacturing and commercialisation of Yescarta in Japan. Subsequently, in the same year, Gilead Sciences acquired Kite.

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2023 Pipeline Report: Testing the Limits

PharmExec

Our annual report spotlighting notable investments in new drug development captures a mix of gradual gains and giant leaps—both equally as promising—in five expanding and diverse therapeutic areas: spinal muscular atrophy, hemophilia A, intranasal and inhaled vaccines, gene-targeted therapy, and RNA therapeutics.

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Study Explores Drivers of Medication Hesitancy in Young Patients With Anxiety Disorders

Pharmacy Times

Cognitive behavioral therapy and pharmacotherapy have been found equally effective treating anxiety disorders, yet some patients are less likely to begin medication treatment.

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Business and Passion

PharmExec

Kimberly Moran, head of rare diseases in the US for UCB, started off working in medicine but quickly learned the importance of the business side of industry—and its role in helping improve the diagnosis and access paths for underserved patient segments.

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FDA Grants Priority Review to Pfizer's RSV Vaccine Candidate for Older Adults

Pharmacy Times

RSVpreF produced vaccine efficacy of 66.7% against respiratory syncytial virus-associated lower respiratory tract illness in older adults.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Opinion: The real crime of Theranos: Loss of trust in real-time diagnostics

STAT

Ramesh Balwani, the chief operating officer of Theranos, was sentenced on Wednesday to nearly 13 years in prison for defrauding investors and patients about the company’s technology. Elizabeth Holmes, his boss, co-conspirator, and former girlfriend, was earlier found guilty of one count of conspiracy to defraud investors, as well as three wire fraud counts tied to specific investors.

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Some COVID-19 Vaccine Adverse Effects May Be Driven by Preexisting Hesitancy

Pharmacy Times

Both vaccine hesitancy and antivax beliefs are largely fueled by inaccurate reports of adverse effects from vaccines, a new study finds.

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Healthcare dealmaking will heat up in 2023 with plenty of corporate cash, PE 'dry powder'

Fierce Healthcare

Healthcare dealmaking will heat up in 2023 with plenty of corporate cash, PE 'dry powder'. hlandi. Thu, 12/08/2022 - 16:06.

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Public Health Matters - Importance of Student Success, Impacting Pharmacy

Pharmacy Times

Dr. Jaclyn Boyle is assistant dean for Student Success and associate professor of Pharmacy Practice at Northeast Ohio Medical University.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Ex-Theranos exec Sunny Balwani gets 13 years for fraud

pharmaphorum

Ramesh “Sunny” Balwani, the former business partner of Theranos founder Elizabeth Holmes, has been sentenced to nearly 13 years in prison after being convicted of wire fraud. His sentencing comes after ex-Theranos chief executive Holmes was given more than 11 years in prison last month after also being found guilty of defrauding investors in Theranos, which said it had developed technology that could diagnose a host of diseases with just a few drops of blood taken with a finger prick, rather tha

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Survey Identifies Factors in Herpes Zoster Vaccine Hesitancy Among Older Adults

Pharmacy Times

An effective shingles vaccine has been available in China since 2020, but vaccine hesitancy persists in at-risk populations.

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Pediatricians send an SOS to rest of medical community

Fierce Healthcare

Pediatricians send an SOS to rest of medical community. fdiamond. Thu, 12/08/2022 - 07:59.

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FDA Authorizes Bivalent COVID-19 Vaccine Booster for Children 6 Months to 4 Years of Age

Pharmacy Times

Booster shots updated for the Omicron variant BA.4 and BA.5 lineages cleared for children 6 months through 4 years of age.

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Biden administration unveils dashboard to track nonfatal drug overdoses

STAT

The Biden administration is rolling out a new tool meant to help prevent drug deaths: a nationwide database that tracks nonfatal overdoses. The dashboard , known as the Non-Fatal Opioid Overdose Surveillance Tracker, will offer fresh insights about overdose rates, the drug supply, and the effectiveness of local emergency response efforts, the White House said.

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Looking at Prescription Therapies for Atopic Dermatitis Treatment

Drug Topics

A recent article highlighted multiple forms of treatment for atopic dermatitis, detailing their benefits and adverse events.

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STAT+: Mark Cuban teams with a business coalition in bid to lower drug costs for employers

STAT

In his latest bid to expand access to lower-cost medicines, Mark Cuban’s Cost Plus Drug Company will offer discounts directly to a company run by a coalition of 40 large private and public employers, cutting out the usual middlemen in the nation’s opaque pharmaceutical supply chain. The effort involves a partnership with the Purchaser Business Group on Health, whose members will be able to fold the medicines sold by Cuban’s company into existing health benefit plans.

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Implantable Drug Delivery System May Revolutionize HIV Care

Pharmacy Times

Implants could produce and deliver monoclonal anti-HIV antibody therapy for at least 1 year.

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Amid criticism, Stanford turns over review of its president to outside investigator

STAT

Stanford University has hired an outside law firm to lead the investigation of its president over allegations of research misconduct, a decision that comes in the wake of criticisms over potential conflicts of interest in the school’s internal review process.  Mark Filip, a former federal judge and Department of Justice official who now defends white-collar clients, will lead the investigation into Stanford president Marc Tessier-Lavigne, the university said in a statement on Wednesd

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The 50 most-filled prescriptions of 2022

The Checkup by Singlecare

Each year, SingleCare helps users save on thousands of prescription medications ranging from beta blockers, to antidepressants, to anti-seizure medications. Here’s a look at the 50 most-filled prescriptions of 2022. 50 most prescribed drugs of 2022. The following are the most popular drugs based on the most filled scripts through SingleCare from Jan. 1, 2022 through Oct. 31, 2022, excluding opioids and weight-loss drugs.

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Pausing breast cancer treatment for pregnancy appears safe

STAT

Young women diagnosed with breast cancer often must delay pregnancy for years while they take hormone-blocking pills. A reassuring new study finds they can take a two-year break from these drugs to get pregnant without raising their short-term risk of cancer coming back.

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Pharma and RWE: Hitting Its Stride

Pharmaceutical Commerce

Stakeholders are investing heavily in their ability to curate appropriate data sets and devise advanced data-analytics capabilities to harness real-world evidence (RWE) across the entire pharma lifecycle—from drug discovery and development through product launch and commercialization.

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‘All the tech in the world doesn’t solve this’: Rare disease experts push biopharma on equity

STAT

Over the past few years, the biopharmaceutical industry has revved up efforts to diversify clinical trials. But clinical trials for rare diseases are still too often homogeneous. Rare disease experts at the Milken Institute Future of Health Summit on Tuesday had words of warning for biopharma: Don’t let equity efforts peter out. Pharmaceutical companies can’t keep developing trials for rare disease treatments without solving for equity, said Tamar Thompson, head of corporate affair

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The mysterious UK Life Sciences Council

pharmaphorum

Just as the life sciences industry is getting vocal about how it’s faring, given the prospect of having to pay back the government 30% of NHS branded medicines sales in 2023, and as it needs to negotiate a new deal on branded medicines pricing and access that will apply from 2024 onwards – there’s been more talk about the Life Sciences Council (LSC).

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FDA authorizes updated Covid-19 boosters for youngest children

STAT

The Food and Drug Administration announced Thursday it had amended the emergency use authorizations for the updated Moderna and Pfizer-BioNTech Covid-19 boosters, to allow their use in children aged 6 months and older. Previously, the bivalent boosters, which protect against two different strains of the SARS-CoV-2 virus, were only available to children 5 years of age and older.

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Employers estimate health benefits costs will rise 5.4% next year: Mercer

Fierce Healthcare

Employers estimate health benefits costs will rise 5.4% next year: Mercer. pminemyer. Thu, 12/08/2022 - 15:20.

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Walensky says CDC needs more authority from Congress to collect public health data

STAT

WASHINGTON — The Centers of Disease Control and Prevention needs Congress to help it collect more data from state, local, and tribal public health departments, Director Rochelle Walensky said Wednesday evening. “There have been numerous pieces written about how the CDC is not sharing the data on ‘x,’ and I just say, ‘Boy, would I love to share the data on “x.

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US FDA grants EUA for Pfizer-BioNTech’s Omicron-adapted vaccine in children

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted an amendment to the Emergency Use Authorization (EUA) for Pfi z er and BioNTech’s Omicron BA.4/BA.5-adapted bivalent Covid-19 vaccine for usage in children aged six months to four years. The vaccine is indicated for use as a third 3µg dose in the three-dose initial regimen for children of this age group.

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The ‘electric vehicles’ of pharma, Illumina’s boondoggle, & a Theranos sentencing

STAT

Who gets dibs on in-demand medicines? Can you get a refund on an $8 billion buy? And what happens when sweetheart deals go bad? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. STAT’s Elaine Chen joins us to explain how the escalating demand for a potent diabetes drug is putting patients with obesity in a difficult situation.

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Women in Pharma® Makes a Splash at 2022 ISPE Annual Meeting & Expo

ISPE

Women in Pharma® Makes a Splash at 2022 ISPE Annual Meeting & Expo. Trudy Patterson. Thu, 12/08/2022 - 10:41. iSpeak Blog. iSpeak. Women in Pharma® Makes a Splash at 2022 ISPE Annual Meeting & Expo. ISPE. 8 December 2022. ISPE’s Women in Pharma ® group strives to tackle unconscious biases that limit women, and other marginalized groups, within the pharmaceutical community.

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