Tue.Nov 12, 2024

article thumbnail

The recovery community says it offers refuge from opioid addiction. But it’s still hostile to lifesaving addiction medications 

STAT

The last time Mark Palinski went to a Narcotics Anonymous meeting, he was asked to leave and never come back. He stills remembers the argument: All he had done was advocate for the use of the “gold standard” treatment opioid addiction, a common medication called buprenorphine.  To Palinski, buprenorphine is a godsend.

145
145
article thumbnail

Varying Messaging Strategies Increases Likelihood of Vaccination Against HPV

Pharmacy Times

There were differences in the variables that influenced vaccination decision making for adults aged 18 to 26 years and for parents making the decision to vaccinate their child

Vaccines 137
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

STAT+: DOJ sues to block UnitedHealth takeover of home health giant Amedisys

STAT

The Department of Justice on Tuesday sued to prevent UnitedHealth Group from buying Amedisys, one of the largest home health and hospice chains in the country. The DOJ’s lawsuit, which is joined by the attorneys general from Maryland, Illinois, New Jersey, and New York, is one of the agency’s most aggressive actions to halt UnitedHealth from moving further into the delivery of health care.

Insurance 143
article thumbnail

Digital unicorn Lyra Health lays off 2% of workforce amid restructuring, impacting non-clinicians

Fierce Healthcare

Lyra Health, a provider of mental health benefits for employees, laid off 2% of its total workforce last Monday, Fierce Healthcare has learned. | The layoffs affected 77 people, according to a former employee who was part of the cuts and spoke on the condition of anonymity. At least some of the employees received severance for 12 weeks with health benefits.

130
130
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

STAT+: A scrap of data on Amgen’s obesity drug candidate wipes out $12 billion in market value

STAT

On Tuesday, a tiny shred of data on Amgen’s lead obesity candidate — not yet verified — erased $12 billion in market value. The data, spotted by an analyst at Cantor Fitzgerald, focused on concerns about potential side effects with the drug, called MariTide. Once they were shared widely in an investor note, the company’s shares fell 7%, a reminder that its stock is in a highly precarious position ahead of a critical readout of the therapy.

140
140
article thumbnail

AstraZeneca CEO defends corporate oversight, $80B revenue target amid China probes

Fierce Pharma

Despite China’s investigations into insurance fraud, allegedly illegal importation of unapproved drugs and improper collection of patient data that have implicated senior executives, AstraZeneca CE | Despite China’s investigations that have implicated senior executives, AstraZeneca CEO Pascal Soriot argued that the company did not lose oversight and remains on track to achieve his ambitious $80 billion-by-2030 revenue goal.

Insurance 128

More Trending

article thumbnail

COVID-19 Hospital Burden Associated With Increased Inpatient Adverse Events Among Patients With and Without COVID-19

Pharmacy Times

High COVID-19 hospital caseload strain led to increases in inpatient adverse events among patients both with and without SARS-CoV-2 infection.

Hospitals 132
article thumbnail

Opinion: How ADHD wired me for scientific discovery

STAT

Imagine a mind that’s constantly buzzing, leaping from one thought to the next, struggling to filter out the noise of a world that feels perpetually turned up to 11. That’s the experience of living with attention deficit hyperactivity disorder, a reality I know intimately. It has profoundly shaped my journey as a scientist, from the setbacks of my early years to the discoveries I’ve made in my laboratory.

126
126
article thumbnail

Cardinal Health inks two deals worth $3.9B to expand diabetes, gastroenterology businesses

Fierce Healthcare

Cardinal Health plans to buy two companies that will expand its diabetes and gastroenterology businesses as part of an overall strategy to grow its footprint in specialty medicine. | Cardinal Health plans to buy two companies that will expand its diabetes and gastroenterology businesses as part of an overall strategy to grow its footprint in specialty medicine.

123
123
article thumbnail

STAT+: Fueled by a ‘fall off your chair’ discovery and $101 million, Trace launches to take on ALS

STAT

A surprise finding by two independent research teams and a venture capital mega-round have birthed a biotech looking to treat amyotrophic lateral sclerosis with a new strategy. Trace Neurosciences launched on Tuesday to announce that it is developing a genetic treatment targeting UNC13A, a gene linked to both a higher risk of ALS and faster disease progression.

126
126
article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

How DSCSA Serves as the Drug Supply Chain’s Lead Investigator | ASPL 2024

Drug Topics

Pharmacy law experts detailed the Drug Supply Chain Security Act, highlighting the role each entity within the supply chain plays in ensuring the safety and authenticity of US prescription drugs.

98
article thumbnail

STAT+: Despite setback, AbbVie’s big bet on neuroscience has yet to play out

STAT

For AbbVie, the good news this week is that the failure of a high-profile schizophrenia drug in two key trials hardly marks its last opportunity to make strides in neuroscience. The bad news is that the effort might not get any easier. The company has had high hopes for the schizophrenia treatment, called emraclidine, which was the centerpiece of its $9 billion acquisition of Cerevel Therapeutics.

119
119
article thumbnail

Greater Depression Severity Linked with Increased Diabetes Risk

Drug Topics

A recent study found that with greater depression severity, metabolic and clinical characteristics such as HbA1c, fasting blood glucose, and triglyceride levels increased.

98
article thumbnail

STAT+: RNA startup Orna Therapeutics cuts more jobs

STAT

Biotech startup Orna Therapeutics has cut more jobs in its second round of layoffs in the last year, STAT has learned.  Orna was part of a buzzy cohort of companies established in the wake of the Covid pandemic, planning to create a new, more durable type of RNA-based medicines. It launched in 2021 and quickly garnered attention from Gilead subsidiary Kite Pharma, Bristol Myers Squibb, Novartis, and Merck.

117
117
article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

article thumbnail

Overcoming Failure as a Recent Pharmacy Graduate

Pharmacy Times

Failing is not final, and it does not define what kind of pharmacist or resident a student can be.

144
144
article thumbnail

STAT+: AstraZeneca, Daiichi Sankyo change strategy on closely watched cancer drug

STAT

LONDON — AstraZeneca said Tuesday it has had to resubmit a closely watched medicine for U.S. approval in a different form of lung cancer, a step that will delay the drug’s arrival on the market and that will add to questions about how widely it could be used.  The medicine, datopotamab deruxtecan, or Dato-DXd, is a type of next-generation chemotherapy called an antibody-drug conjugate that AstraZeneca and other companies have been pouring investments into.

article thumbnail

Building Resilience: Opportunities for US Pharma to Strengthen Public Health in Africa Amid Changing Aid Policies

Pharmacy Times

Africa’s rapidly growing population, expected to reach 2.5 billion by 2050, means an increasing demand for health care and medications.

123
123
article thumbnail

DOJ sues to block UnitedHealth's $3.3B acquisition of Amedisys

Fierce Healthcare

The Department of Justice filed suit on Tuesday to block UnitedHealth's $3.3 billion acquisition of home health company Amedisys, arguing that the deal would stifle competition in this space. | The Department of Justice filed suit on Tuesday to block UnitedHealth's $3.3 billion acquisition of home health company Amedisys, arguing that the deal would stifle competition in this space.

107
107
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

Q&A: Insights on HIV Care, Pharmacists’ Expanding Role

Drug Topics

Cassandra Esperant, PharmD, AAHIVP, leverages her expertise as a clinical pharmacist to advocate for the well-being of individuals with HIV.

98
article thumbnail

Pharmacists Combat Flu Misinformation and Expand Vaccine Access

Pharmacy Times

Kristi Veis discusses the importance of flu vaccinations and the role of pharmacists in administering them.

Vaccines 132
article thumbnail

FDA rejects Intercept's ask for Ocaliva full nod in rare liver disease, but accelerated approval remains

Fierce Pharma

In the wake of an unfavorable advisory committee meeting in September, Intercept Pharmaceuticals’ bid to win full approval for its liver disease drug Ocaliva has come up short. | Intercept received a complete response letter from the FDA, dashing the company’s hopes of turning Ocaliva’s accelerated green light into a traditional approval for the rare autoimmune disease primary biliary cholangitis.

FDA 106
article thumbnail

Next gen wearables: Transforming remote patient care

pharmaphorum

Virtual wards (also known as hospital at home) allow patients to get the care they need at home safely and conveniently, rather than being in hospital. The NHS is increasingly introducing virtual wards to support people at the place they call home, including care homes. In today’s podcast, web editor Nicole Raleigh speaks with Dr Samuel Ewing, global head of pharma partnerships at Doccla, about the next generation of digital tools such as wearable medical devices, as well as remote patient monit

article thumbnail

New Model Can Assess Blast Phase Progression Risk in Myeloproliferative Neoplasms

Pharmacy Times

According to the study, 20% of patients with myeloproliferative neoplasms progress to blast phase.

132
132
article thumbnail

Merck drug for rare tumour hits phase 3 target

pharmaphorum

Merck KGaA is shaping up to take on Daiichi Sankyo and Ono Pharma in the market for tenosynovial giant cell tumour (TGCT) therapies after its drug candidate pimicotinib cleared a phase 3 trial.The German group said the CSF-1R inhibitor given as a once-daily, oral dose hit its primary endpoint in the MANEUVER study, achieving an objective response rate (ORR) at week 25 of 54% compared to 3.2% for a matched placebo in patients with TGCT, a rare disease affecting the joints and tendons.

103
103
article thumbnail

STAT+: Pharmalittle: We’re reading about 23andMe retrenching, AstraZeneca reworking cancer drug plans, and more

STAT

Top of the morning to you. And a fine one it is. Lots of sunshine and clear blue skies are once again enveloping the Pharmalot campus, where the official mascots are bounding about the grounds in search of creatures to annoy. As for us, we are as busy as ever hunting and gathering items of interest. We trust you have your own hectic agendas. So join us as we hoist the ever-present cup of stimulation — our choice today is coconut rum — and attack the fast-growing to-do list.

article thumbnail

The Nuances of Marijuana’s Potential Rescheduling | ASPL 2024

Drug Topics

FDA experts gathered to discuss the DEA’s rescheduling of marijuana and how it will impact the pharmaceutical supply chain.

FDA 98
article thumbnail

Bayer's rising prostate cancer star Nubeqa crosses blockbuster barrier as Xarelto continues downward descent

Fierce Pharma

Despite generic headwinds to Xarelto and challenges across different sectors of the conglomerate suggesting “twists and turns” in the road ahead, Bayer is confident that the course it’s laid out th | As Xarelto generics continue to eat away at sales, Bayer's Nubeqa and Kerendia are picking up the slack while Regeneron-partnered Eylea makes for a solid base.

98
article thumbnail

Growing threat of AMR: UN calls for urgent global action

pharmaphorum

The United Nations is calling for urgent global action to address the growing threat of antimicrobial resistance (AMR). Learn more about this pressing issue and what steps can be taken to combat it effectively.

98
article thumbnail

Pfizer explores sale of hospital drugs unit amid activist investor’s call for accountability: Reuters

Fierce Pharma

After a series of acquisitions and an activist investor’s accusation of overspending, Pfizer is exploring an opportunity to slim down by divesting its hospital drugs unit,

article thumbnail

Chasing $80bn sales target, AZ unveils $3.5bn US investment

pharmaphorum

AstraZeneca plans to invest a whopping $3.5 billion to expand its R&D and manufacturing operations in the US by 2026 as part of a drive to raise its revenues to $80 billion by the end of the decade.The programme – part of the pharma group's Ambition 2030 effort – will include the construction of a new R&D centre at Kendall Square in the heart of the biopharma hub in Cambridge, Massachusetts, and a biologics manufacturing facility in Maryland.

96
article thumbnail

Proposed Biosimilar to Ocrelizumab Shows Comparability With Reference Product

Pharmacy Times

Ocrelizumab (Ocrevus; Genentech) is used for the management and treatment of multiple sclerosis.

123
123
article thumbnail

NHS England relaunches anti-smoking pill programme

pharmaphorum

'Game-changer' daily pill to quit smoking returns to NHS after three-year absence after a deal between Teva and NHS England

103
103
article thumbnail

Abbisko’s pimicotinib hits primary endpoint in phase 3 TGCT trial

Outsourcing Pharma

Abbiskoâs small molecule drug pimicotinib has smashed the primary goal of a phase 3 trial for the treatment of tenosynovial giant cell tumor (TGCT), taking the asset a step further to the market in China and elsewhere.

88