Tue.Aug 16, 2022

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Right under our noses: Could COVID-19 vaccines be better as nasal spray?

PharmaVoice

Nasal vaccines under development by Codagenix, Xanadu Bio and others have the potential to finally help reduce virus transmission and breakthrough infections.

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ICYMI: New research builds upon growing body of evidence on value of COVID-19 treatments and vaccines

PhRMA

Innovative biopharmaceutical research companies have been dedicated to fighting COVID-19 for over two years. Since the start of the pandemic, America’s biopharmaceutical companies have worked around the clock to research, develop and manufacture treatments and vaccines to fight COVID-19. We’ve made unprecedented progress in a short time thanks to decades of experience having produced over 14 billion vaccines globally to date.

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The CEO in the ophthalmologist’s coat

PharmaVoice

In balancing two roles — Lexitas CEO and practicing physician — George Magrath brings a patient-first perspective to developing and advancing eye treatments.

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Insurer Tools to Save Seniors Money on Prescription Drugs Could Put Them at Higher Risk of Stroke

Pharmacy Times

Insurer and pharmacy benefit manager policies used to cut the cost of drugs could be so time consuming that they could put newly diagnosed atrial fibrillation patients at risk of stroke.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Auransa, Polaris harness AI, quantum computing to discover cancer drugs

Outsourcing Pharma

The AI and QC specialists have joined to use AI and QC in order to discover biological pathways relevant to the treatment of triple-negative breast cancer.

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Study Results Link Neck, Shoulder Pain With Worse Headache, Migraine Symptoms

Pharmacy Times

Investigators aimed to determine how individuals with and without concomitant NSP differ in characteristics and in their perception of treatment responses to analgesics.

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More Trending

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Common Antibiotic Associated with Rare, Severe Adverse Effects for Patients with Advanced Chronic Kidney Disease

Pharmacy Times

A new study warns that fluoroquinolone could increase the risk of altered mental status and hospitalizations for advanced chronic kidney disease patients, though it is rare.

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Gilead to acquire global rights of Trodelvy from Everest

Pharmaceutical Technology

Gilead Sciences has entered an agreement with Everest Medicines to acquire complete rights to develop and market Trodelvy (sacituzumab govitecan) in Greater China, Singapore, South Korea, Philippines, Vietnam, Thailand, Indonesia, Mongolia and Malaysia. According to the deal, Everest is entitled to receive an upfront payment of $280m from Gilead. Furthermore, Gilead will make potential payments of up to $175m to Everest on meeting certain regulatory and commercial milestones.

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FDA Finalizes Rule For Availability of OTC Hearing Aids

Pharmacy Times

The FDA has issued a rule that will grant millions of Americans access to OTC hearing aids in pharmacies or online without a prescription or medical exam required.

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Phase III trial shows tislelizumab improves outcomes for liver cancer patients

European Pharmaceutical Review

The Phase III RATIONALE 301 study evaluated the efficacy and safety of tislelizumab versus sorafenib as a first-line systemic treatment in participants with unresectable hepatocellular carcinoma. . Hepatocellular carcinoma, or HCC, is the sixth most common type of cancer worldwide. HCC accounted for more approximately 85 percent of the 900,000 new liver cancer cases in 2020, according to the Globocan 2020 database. .

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Study: Mass Screening, Peer Support Helps Reduce HIV Transmission, Community Viral Load

Pharmacy Times

High rates of HIV can decrease with community-based support.

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FDA Inspections Back Up To Speed (Except Those Now Deemed Unnecessary)

The FDA Law Blog

By Douglas B. Farquhar — Those of us who work frequently on FDA inspections of drug and medical device manufacturing facilities have noticed an uptick in regular inspections after a dramatic falloff during the first two years of COVID. That impression was corroborated this week at the GMP by the Sea conference when Douglas Throckmorton, Deputy Director for Regulatory Programs at FDA’s Center for Drug Evaluation and Research, stated that domestic FDA inspections of facilities have been performed

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Prevent or Reduce Atopic Dermatitis Flare-Ups

Pharmacy Times

Guidelines provide information on the management and treatment of this common skin condition.

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Monkeypox Vaccine Emergency Use Authorization

Digital Pharmacist

On August 9th, 2022, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the JYNNEOS vaccine. Here is what you need to know about the monkeypox vaccine emergency use authorization. . JYNNEOS Vaccine Authorization Details . This authorization allows healthcare providers to administer the vaccine by intradermal injection for high risk individuals that are 18 years of age or older.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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PCV13 Vaccination May Reduce Incidence of Acute Chest Syndrome for Children with Sickle-Cell Disease

Pharmacy Times

A potential public health benefit of 13-valent pneumococcal conjugate vaccine is the reduction of acute chest syndrome among children with sickle-cell disease.

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Queen’s Award for Enterprise goes to SGS’s Quay Pharma

European Pharmaceutical Review

The Queen’s Award for Enterprise is the UK’s highest accolade for business success and recognises the strength of Quay Pharma’s export sales, which, according to SGS, have comprised at least 55 percent of its business since 2010. The enterprise also noted that in the last three years its overseas sales had more than doubled. The International Trade category recognises those who have had a clear business strategy for entering new markets abroad, have overcome the challenges faced by exporte

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New Psychoeducational Suicide Prevention Module Found Superior to Usual Care in Patients With Substance Use Disorders

Pharmacy Times

The Preventing Addiction Related Suicide module was found to better improve suicide knowledge, increase help-seeking behaviors, and reduce maladaptive attitudes compared with usual care for patients with substance use disorders.

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Parkinson’s monitoring tech advances in NICE approval process

Outsourcing Pharma

The National Institute for Health and Care Excellence is weighing the viability of PD Neurotechnologyâs PDMonitor system for Parkinsonâs disease patients.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Social Determinants of Health Play Key Role in Patients’ Health Journey

Pharmacy Times

Specialty pharmacies are well positioned to address disparities that affect outcomes.

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New Report Looks to the Supply Chains of the Future

Pharmaceutical Commerce

Three of the authors of a new EY study exploring the evolution of industry supply chain strategies and the long-term implications for healthcare delivery across three major trade regions discuss the report’s key findings and share their predictions as we move into Q3.

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Oncology Overview: Treatment of Chronic Lymphocytic Leukemia with Ibrutinib, Venetoclax

Pharmacy Times

Both ibrutinib (Imbruvica) and venetoclax (Venclexta) carry an approved indication for use in chronic lymphocytic leukemia but do not often lead to complete remission, and therapy routinely continues indefinitely or until disease progression.

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UK advisors back Moderna’s bivalent shot for autumn COVID booster

pharmaphorum

The UK’s Joint Committee on Vaccinations and Immunisations (JCVI) has said that Moderna’s bivalent COVID-19 vaccine should be used for the autumn booster campaign in adults. The new recommendations came hard on the heels of the authorisation of the new shot, which provides protection against the original strain of the virus and the Omicron variant, by the Medicines and Healthcare products Regulatory Agency (MHRA).

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American Oncology Network Comments Against CMS’ 2023 Outpatient Prospective Payment System

Pharmacy Times

The new proposal will have grave effects on the sustainability of community oncology practices.

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More big wins for the AstraZeneca-Daiichi Sankyo collaboration

Pharmaceutical Technology

In 2019, Daiichi Sankyo entered a global development and commercialisation agreement with AstraZeneca for Daiichi Sankyo’s lead antibody-drug conjugate (ADC), Enhertu (trastuzumab deruxtecan), in a deal worth $6.9bn. This was followed by a further deal for the global development and commercialisation of another ADC, datopotamab deruxtecan (DS-1062) in 2020, with a deal value of up to $6bn.

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Daily OTC Pearl: ClearoGout

Pharmacy Times

ClearoGout aids in the prevention of gout attacks.

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Enhancing Oncology Clinical Trials Through The Use Of Digital Technologies

PharmExec

Wed, Aug 17, 2022 2:00 PM EDT Recent advances in both oncology drug development and novel digital technologies provide a ripe opportunity to enhance the clinical trial process. Join Colin Weller and Musaddiq Khan from Medable as they discuss the key considerations around these innovations.

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Daily Medication Pearl: Febuxostat (Uloric)

Pharmacy Times

Febuxostat) Uloric is a xanthine oxidase inhibitor indicated for the chronic management of hyperuricemia in patients with gout.

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Q32 Bio and Horizon partner to develop autoimmune disease treatment

Pharmaceutical Technology

Q32 Bio has signed a partnership and option agreement with Horizon Therapeutics for developing ADX-914 to treat autoimmune ailments. According to the deal, Horizon will provide the funding to develop the therapy until the conclusion of its two Phase II clinical trials. Furthermore, Q32 will oversee the conduct of all programme-linked works. Under the agreement, Horizon will hold an option for the acquisition of the ADX-914 programme, which is exercisable through a period after concluding the Pha

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Op-Ed: Unnecessary Transfusions in Hospitals May Be Fueling the Blood Shortage

Pharmacy Times

With costs for blood and blood products continuing to rise, appropriate blood use by hospitals is more important than ever.

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Digital health’s rapid growth spurt comes home to roost

pharmaphorum

With fears of a recession and inflation running high, the boom period for digital health apps looks to be waning. In this article, Ben Hargreaves looks at how companies have reacted to an unfavourable economic climate and what that could mean for the long-term growth of the industry. The idea 12 months ago that the health and wellness app space could soon be facing a crisis would have seemed highly pessimistic.

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Evonetix commences access programme for synthesised DNA

Pharma Times

Researchers are invited to apply to receive DNA that has been synthesised using Evonetix’s platform

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On heels of new data, Gilead pays $455m for Asian Trodelvy rights

pharmaphorum

On the same day as it reported encouraging new data for its cancer drug Trodelvy, Gilead Sciences has agreed a deal to buy rights to the drug in Asia held by Chinese drugmaker Everest Medicines. The US company said it is paying $280 million upfront to acquire rights to the drug in Greater China, South Korea, Singapore, Indonesia, Philippines, Vietnam, Thailand, Malaysia and Mongolia, with another $175 million tied to the achievement of regulatory and commercial objectives in those territories.

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Lynparza in combination with abiraterone granted priority review in US

Pharma Times

New therapy is aimed at patients with metastatic castration-resistant prostate cancer

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