Mon.Dec 19, 2022

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With mpox cases mysteriously dwindling, scientists search for answers

PharmaVoice

Was it a public health victory? Or did mpox ‘burn itself out?’ An epidemiologist weighs in.

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What you should know about real-world evidence and drug development

PhRMA

Recently, industry leaders, regulators, academics, data partners, and patient advocates gathered in Washington, D.C., to discuss using real-world data and real-world evidence for regulatory decision-making. The discussion explored emerging analytical methodologies to address the challenge of mitigating sources of bias and confounding variables that come up in nearly all sources of real-word data.

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Digestive Health Treatments Near FDA Submission

Drug Topics

Successful clinical trials for digestive health treatments may soon yield approvals.

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Blood cancer cures aren’t here yet — but incremental combinations bring the field closer

PharmaVoice

A series of small successes showed promise for the future of blood cancer treatments, particularly in the arena of drug combinations.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Copay Caps for Insulin Lower Total Spending for Medicare Beneficiaries

Drug Topics

The Medicare Part D Senior Savings Model — a CMS effort to test $35 copays for insulin — led to lowered total costs for beneficiaries.

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Experts Warn of Spread of Lung Infection-Causing Fungi

Pharmacy Times

Traditionally, endemic fungi are characterized by geographical distribution, however, disease-causing fungi may infect people beyond these havens.

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More Trending

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Monitoring for Treatment Complications in Patients With Hemophilia A

Pharmacy Times

An array of complications may arise associated with treatment of hemophilia A.

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2023 forecast: Amid dwindling COVID relief funds, rural hospitals face a 'fiscal cliff'

Fierce Healthcare

2023 forecast: Amid dwindling COVID relief funds, rural hospitals face a 'fiscal cliff'. agliadkovskaya. Mon, 12/19/2022 - 14:42.

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Artificial Intelligence Shows Promise in Detection of Anxiety Disorders, Depression

Pharmacy Times

Investigators establish that audio and/or facial video features have been most analyzed by machine learning, followed by electroencephalography signals.

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2023 forecast: Providers embrace start of new requirements on health equity

Fierce Healthcare

2023 forecast: Providers embrace start of new requirements on health equity. rking. Mon, 12/19/2022 - 15:28.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Study Results Suggest Exercise, Mindfulness Do Not Boost Cognitive Function in Older Adults

Pharmacy Times

Although physical activity and the practice of being present in the moment are associated with many benefits, analysis shows that neither led to measurable improvements in brain health.

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Atara makes history with world-first nod for allogeneic T-cell therapy Ebvallo

Fierce Pharma

Atara makes history with world-first nod for allogeneic T-cell therapy Ebvallo. fkansteiner. Mon, 12/19/2022 - 14:06.

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Albuminuria is More Prevalent in Type 1 Diabetes

Pharmacy Times

Age was a contributing factor of chronic kidney disease and albuminuria in patients with type 1 and type 2 diabetes.

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Could ketamine-assisted therapy help treat alcoholism?

European Pharmaceutical Review

A new £2.4 million Phase III trial will determine if ketamine-assisted therapy can help those with severe alcohol use disorder to stay off alcohol for longer. Led by the University of Exeter and funded by the Medical Research Council (MRC) and the National Institute for Health and Care Research (NIHR), “[t]his is the largest trial of its kind in the world and builds on our earlier, smaller positive trial,” stated Professor Anne Lingford-Hughes, Professor of Addiction Biology at Imperial College

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Intravenous Immunoglobulin May Improve Severe OCD in Children

Pharmacy Times

Treatment observably eased obsessive-compulsive disorder symptom severity in young patients, however, symptoms still caused students to be absent from school at least 2 days every month.

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COVID-19 vaccines protect against more than just COVID: study

Fierce Healthcare

COVID-19 vaccines protect against more than just COVID: study. fdiamond. Mon, 12/19/2022 - 12:03.

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Immunotherapy Makes Major Strides for First-line Treatment of Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Pharmacy Times

Specific immune checkpoint inhibitors added to frontline chemotherapy have transformed modern clinical practice.

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CDC: Bivalent vaccine cuts risk of COVID hospitalization by half

Fierce Healthcare

CDC: Bivalent vaccine cuts risk of COVID hospitalization by half. fdiamond. Mon, 12/19/2022 - 15:28.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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FDA Approves Cariprazine for Major Depressive Disorder

Pharmacy Times

Cariprazine (Vraylar; AbbVie, Gedeon Richter) is indicated as an adjunctive therapy to antidepressants for treating adult patients with major depressive disorder.

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Novartis prunes nearly 300 jobs in Garden State as corporate slimdown rolls on

Fierce Pharma

Novartis prunes nearly 300 jobs in Garden State as corporate slimdown rolls on. fkansteiner. Mon, 12/19/2022 - 10:53.

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Standard of Care in Treatment of Hemophilia A

Pharmacy Times

Atta Chowdhry, RPh, opens a discussion surrounding prophylactic treatment in patients diagnosed with hemophilia A.

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Former VA secretary's latest venture, Override, emerges out of stealth to tackle chronic pain

Fierce Healthcare

Former VA secretary's latest venture, Override, emerges out of stealth to tackle chronic pain. hlandi. Mon, 12/19/2022 - 07:59.

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Pharmacist Appreciation

Pharmacy Times

Tim Whitten, BSPharm, MBA, CEO & President of Taiho Oncology Inc discusses the critical impacts of pharmacists across the health care landscape.

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Epic plans to overhaul its app market, opens new 'connection hub' for developers. Here are key things to know

Fierce Healthcare

Epic plans to overhaul its app market, opens new 'connection hub' for developers. Here are key things to know. hlandi. Mon, 12/19/2022 - 11:56.

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Study Finds Positive Psychology Can Help Mediate Some Symptoms of Colorectal Cancer

Pharmacy Times

Identifying how survivors adjust to their cancer may help health care providers provide tailored self-management skills.

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Sanofi and Innate Pharma extend cancer therapeutics partnership

Pharmaceutical Technology

Sanofi has extended the partnership with Innate Pharma for natural killer (NK) cell therapeutics in oncology. With the latest development, Sanofi will licence a NK cell engager programme that acts on B7H3 from the antibody-based NK cell engager therapeutics (ANKET) platform of Innate. Under the latest licence deal, Sanofi will make an upfront payment of $26.4m (€25m) to Innate.

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Pemetrexed Injection Receives FDA Approval for Fifth Indication in NSCLC Treatment

Pharmacy Times

The additional indication expands its therapeutic role beyond advanced non-small cell lung cancer.

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Congress reaches major health policy deal on Medicare, Medicaid, and pandemic preparedness

STAT

WASHINGTON — Leaders in Congress have reached a sweeping deal to ease Medicare pay cuts to doctors, make major changes to post-pandemic Medicaid policy, and to help prepare for future pandemics. Lawmakers are aiming to pass a health care policy package along with legislation to fund the federal government by Friday. The details of the omnibus spending package were confirmed by two lobbyists and two congressional aides.

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It Is a Common Cold, Not COVID-19

Pharmacy Times

Similar symptoms often make it difficult for patients to tell the contagious respiratory conditions apart.

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Pharma wins changes in bill regarding FDA’s accelerated approval

STAT

A bill that makes it easier for the Food and Drug Administration to withdraw drugs that were approved under an accelerated timeline also dropped provisions the industry had opposed, according to three drug lobbyists. The legislation was spurred by the fracas over the Alzheimer’s drug Aduhelm, which received a so-called accelerated approval. Nearly every member of an FDA advisory panel voted against approving the Biogen drug, though many advocates for patients with debilitating conditions

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CHMP backs Amicus’ therapy for Pompe disease

pharmaphorum

Amicus Therapeutics could be just weeks away from getting EU approval for its new Pompe disease therapy Pombiliti after getting a positive opinion on the drug from the EMA’s human medicines committee. The CHMP said late last week it was recommending Pombiliti (cipaglucosidase alfa or ATB200) as an infused therapy for late-onset Pompe disease in adults given in combination with the enzyme stabiliser miglustat in a regimen known as AT-GAA.

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We finally have new drugs for sickle cell disease. Why are so few patients taking them?

STAT

At first, Lena Harvey didn’t realize anything had changed. She just started doing strange, unexpected things: Cleaning her living room, for example, or playing with her puppy, a black schnauzer named Apollo. It hit her as she walked in from the patio one day. She looked at her husband, Anthony, and asked, “Honey, I haven’t been complaining about pain, have I?

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Watch DSN: Kroger Health’s Lindholz highlights importance of Food as Medicine platform

Drug Store News

Colleen Lindholz, president of Kroger Health, discusses the Food as Medicine platform and its mission to help people enjoy food so they can live healthier lives.

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