Mon.Apr 15, 2024

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Chronic Pain and Mental Health: A Compounding Relationship

Drug Topics

In the United States, 12 million adults suffer from co-occurring chronic pain and anxiety or depression. Erasing stigmas, educating patients, and tailoring interventions can help to improve outcomes.

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STAT+: Can investing in infectious disease pay off? Vir Biotechnology’s tightrope walk shows it’s a struggle

STAT

Nearly a decade ago, venture capitalist Bob Nelsen called industry veteran Vicki Sato to pitch her on launching a large company dedicated to tackling the world’s worst pathogens. “This is a crazy idea,” Sato said. Nelsen, managing director of ARCH Venture, had made a name and fortune off crazy ideas, but generally it was the science that sounded crazy: engineering cells to cure cancer, finding drugs to slow aging.

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Trending Sources

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DEA Shares Tips to Protect Against Pharmacy Break-Ins

Drug Topics

A string of thefts at local pharmacies has spurred the DEA to issue warnings and share tips for independent pharmacists to keep their stores secure.

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STAT+: Thanks to CVS, a biosimilar version of AbbVie’s Humira is grabbing huge market share

STAT

The number of new prescriptions written for biosimilar versions of the Humira rheumatoid arthritis treatment, one of the best-selling medicines in the U.S., surged to 36% from just 5% during the first week of April, thanks to the expanding reach that CVS Health has over the prescription drug market. The big jump was attributed to one particular biosimilar called Hyrimoz, which is manufactured by Sandoz, a unit of Novartis that is a leading supplier of generic and biosimilar medicines.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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COVID-19 Not Associated With Increased Risk of Asthma Development in Children

Drug Topics

A study from the Children’s Hospital of Philadelphia found that a positive PCR test was not associated with an increased risk of a new asthma diagnosis in patients ages 1 to 16.

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Opinion: ADHD is often overlooked in females. They need help, too

STAT

Boys aren’t the only people who develop attention-deficit/hyperactivity disorder (ADHD). It also affects girls and young women and adults of both genders. Yet females with ADHD are chronically underdiagnosed and undertreated. Individuals with this condition die about 10 years earlier than those without it. They are also up to three times more likely to experience a variety of nonfatal negative life events, such as serious car accidents, unintended teen pregnancy, episodes of anxiety and d

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STAT+: Mass General Brigham is ready to move on without Dana-Farber, CEO says

STAT

CHICAGO — The split between Dana-Farber Cancer Institute and Mass General Brigham has been messy. Some people who don’t see breakups coming wonder what went wrong, and maybe channel the sorrow into a love ballad. But Mass General Brigham is taking a different tack — it’s simply getting over it. The $20 billion nonprofit hospital system is now plotting out how its cancer programs will look in a post-Dana-Farber world.

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Elevance Health taps PE firm CD&R for primary care partnership

Fierce Healthcare

Elevance Health is teaming up with private equity firm Clayton, Dubilier & Rice in its latest bid to expand access to advanced primary care. | Elevance Health is teaming up with private equity firm Clayton, Dubilier & Rice in its latest bid to expand access to advanced primary care.

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Psychedelic treatments on cusp of approval, but questions remain

pharmaphorum

Psychedelic treatments for conditions like PTSD using substances like MDMA are on the brink of approval, but there are still unanswered questions surrounding their effectiveness and potential risks. Learn more here.

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OTC Contraception Hits Shelves

Pharmacy Times

Opill is a nonprescription, progestin-only contraceptive pill, with nearly 50 years of use and data supporting the safety and effectiveness of progestin-only pills.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Ultragenyx reports early success with Angelman syndrome drug, backing up 2022 acquisition

STAT

Ultragenyx has found early success with its experimental treatment for the rare disease Angelman syndrome, supporting the company’s decision to acquire its development partner two years ago. Ultragenyx is one of the few companies developing a treatment for Angelman syndrome , a genetic condition that causes delayed development, problems with speech and balance, mental disability, and sometimes seizures.

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Cerebral agrees to $7M settlement with FTC, DOJ over user data sharing, cancellation practices

Fierce Healthcare

Virtual mental health startup Cerebral has agreed to pay the government more than $7 million, abide by a “first-of-its-kind” restriction on the handling of consumers’ sensitive information and rewo | The embattled mental health startup had inappropriately shared 3.2 million people's sensitive information, upheld "sloppy security practices" and slow-walked consumers trying to cancel services, the FTC said.

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STAT+: Cerebral to pay $7 million fine and limit health data use for ads under federal order

STAT

Telehealth company Cerebral will limit the consumer health data it uses for advertising purposes under a new order announced by the Federal Trade Commission Monday. Cerebral, a startup best known for dispensing counseling services and prescriptions for conditions like anxiety and depression, has also agreed to pay $7 million to resolve charges that it disclosed customers’ personal health information to third parties for ads, and that it did not honor its promise to make cancellation easy

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Head physician's 'inappropriate' alterations suspend Memorial Hermann transplant programs

Fierce Healthcare

Houston’s Memorial Hermann-Texas Medical Center is working to resume liver and kidney transplant programs that were paused amid evidence that a head physician had made “inappropriate” alterati | Houston’s Memorial Hermann-Texas Medical Center's liver and kidney transplant programs have been suspended for several days. The organization said it's reached out to affected patients and is working to "quickly" restart the programs, but as of Monday offered no potential timeline.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Regeneron launches $500m venture capital arm

pharmaphorum

Regeneron has formed a corporate venture capital unit with $100 million a year to invest over the next five years in “biopharmaceutical, healthcare, and health technology” start-ups.

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UnitedHealth, CVS, Molina the big losers in Florida Medicaid contract awards

Fierce Healthcare

Insurers Humana, Centene and Elevance Health were selected as the three statewide Medicaid contract awardees in Florida on April 12. | Just three insurers earned statewide contracts for Florida's state-run managed care program, but UnitedHealth, Aetna and Molina were not selected.

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Novartis touts surrogate endpoint win, nabs priority review for Fabhalta in IgAN

Fierce Pharma

A Novartis drug with "pipeline in a pill" potential, according to one analyst group, has delivered on that promise once again. | In a phase 3 trial, treatment with Fabhalta led to a statistically significant 38.3% reduction of proteinuria (protein in the urine) in patients with IgA nephropathy, Novartis said on Monday.

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STAT+: Pharmalittle: We’re reading about a J&J cough syrup, a Pfizer and Moderna patent suit, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was invigorating and refreshing, because that oh-so familiar routine of phone calls, online meetings, and rushing about has predictably returned. But what can you do? The world, such as it is, continues to spin. So time to give it a nudge in a better direction with a cup or three of stimulation.

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Pfizer, BioNTech win pause in patent infringement case from rival Moderna

Fierce Pharma

After nearly two years of legal back and forth, Pfizer and its German partner BioNTech have won a brief reprieve in their patent fight against mRNA rival Moderna. | In a docket entry dated Friday, Massachusetts federal judge Richard G. Stearns granted a stay on Moderna's COVID-19 vaccine patent infringement lawsuit against Pfizer and BioNTech. The move will give the Patent Trial and Appeal Board more time to review challenges against two of the three relevant patents in the litigation.

Vaccines 118
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Traditional gene therapies are uber-niche. Ocugen hopes to change that.

PharmaVoice

The biotech is developing a ‘gene-agnostic’ approach to expand the patient pool for gene therapies.

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9 health benefits of bananas

The Checkup by Singlecare

While bananas might not be the trendiest fruit (unless you count Andy Warhol’s version), they’re rightfully regarded as one of the original superfoods. They contain carbohydrates, soluble fiber, vitamin C—which helps protect against free radicals—vitamin B6, provitamin A, potassium, and magnesium. This powerful combination of essential nutrients makes the bright yellow fruit a great choice for people who are looking to maintain a healthy weight, lower blood pressure, improve skin health, and mor

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Activist hedge fund seeks big shake-up at Novavax

pharmaphorum

Shah Capital has fired a broadside at the management team of Novavax, seeking a change in leadership at the vaccine company and the appointment of two handpicked directors to the board. In an open letter, the hedge fund accuses Novavax’s leadership of squandering its “many significant competitive advantages and sizeable market opportunity” due to “self-inflicted problems” under the current team led by chief executive John Jacobs.

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In This Issue: Total Pharmacy April 2024

Drug Topics

See what's trending in pharmacy with a preview of the Total Pharmacy April issue.

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After ph3 win, Roche eyes earlier use of Columvi in DLBCL

pharmaphorum

Roche’s CD20xCD3 bispecific antibody Columvi has improved survival when used as a second-line therapy for diffuse large B-cell lymphoma (DLBCL) in a phase 3 trial, setting up regulatory filings for earlier use of the drug in the treatment pathway.

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Medicare expects a big spike in spending on Leqembi

STAT

You’re reading the web version of Health Care Inc.,  STAT’s weekly newsletter  following the flow of money in medicine.  Sign up  to get it in your inbox every Monday.  Anne Klibanski on the Dana-Farber split Mass General Brigham didn’t foresee the breakup with Dana-Farber Cancer Institute. But there won’t be any texts begging Dana-Farber to come back.

Hospitals 106
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Enhancing Breast Cancer Treatment: Expanding CDK4/6 Inhibitor Use in the Early-Stage Setting

Pharmacy Times

Danielle Roman, PharmD, BCOP, discusses the efficacy and safety outcomes of CDK4/6 inhibitors in early-stage breast cancer, as well as key considerations for CDK4/6 inhibitors in this indication.

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Advancing medicine requires more secure supply chains

pharmaphorum

The advancement of medicine is dependent on secure pharmaceutical supply chains. Discover why ensuring the security of these chains is crucial for the development and distribution of life-saving medications.

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Study Finds No Differences Between Adalimumab, Biosimilar for Inflammatory Bowel Disease

Pharmacy Times

There was no difference observed between adalimumab (Humira; AbbVie) and adalimumab-aacf (Idacio; Fresenius Kabi) for those who switched to the biosimilar.

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Healthware re-launches as Eversana Intouch full service affiliate

pharmaphorum

Life sciences service provider (and pharmaphorum parent company) Eversana has completed the integration of Healthware Group, the Italy-based global agency and consultancy it acquired in October. The group will now be known as Eversana Intouch Healthware and will operate as Eversana’s sixth full-service affiliate.

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Empowering Oncology Pharmacists: Driving Innovation and Advancement Through Pharmacist-Led Research

Pharmacy Times

The impact pharmacist-led research on oncology pharmacy practice in the field of oncology is undeniable.

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Study warns of chronic kidney disease timebomb

pharmaphorum

Up to one in six people in eight industrialised nations could be suffering from chronic kidney disease (CKD) by 2032, with dire consequences for “patients, [the] planet, and economies,” says a new study.

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A two-decade bet on Seagen pays off

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hi there, Meghana here — a little wistful about the departure of the illustrious Damian Garde but extremely excited about a fantastic newsletter co-author we’ll introduce soon.

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FDA Grants Orphan Drug Designation for the Active Ingredient in MVD Vaccine

Pharmacy Times

Although the vaccine has not yet been tested in humans, it demonstrated 100% efficacy in protecting primates who were injected with human Marburg virus disease.

Vaccines 107
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Boehringer Ingelheim leans on late-stage pipeline, plots 25 new launches over the next decade

Fierce Pharma

Boehringer Ingelheim’s 2023 was largely marked by the highly anticipated launch of its Cyltezo, the first interchangeable biosimilar to AbbVie’s Humira. | The company's late-stage pipeline focuses on oncology, cardiorespiratory diseases, mental health and cardiovascular-renal-metabolic conditions. Boehringer looks to kick off ten new phase 2 and 3 trials in the next 12-18 months, it said in its earnings release.

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