Mon.Apr 14, 2025

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Why CDC cuts are being called ‘the greatest gift to tobacco industry in the last half-century’

STAT

In the earliest ads, Terrie Hall wears a scarf around her throat to cover the artificial voice box that helps her speak. She talks about smoking on the day of her surgery; how she wishes she’d recorded her voice so her grandchildren would know how she used to sound. Two years later, just days before her death from cancer at age 53, Hall insisted on filming again from her hospital bed in North Carolina.

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A pharmacist’s take on actions from the child asthma and anaphylaxis deaths report

Hospital Pharmacy Europe

The National Child Mortality Database report on child deaths related to asthma and allergies was released in December 2024, providing sobering insights. Pharmacist Ravijyot Saggu offers an expert summary, emphasising key points from the thematic report and discussing necessary future actions. One in 11 children and young people in the UK has asthma and it is the most common long-term medical condition in children in the UK. 1 Additionally, the country has one of the highest rates of prevalence,

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US begins inquiry into pharmaceutical and chip imports in bid to impose tariffs

The Guardian - Pharmaceutical Industry

Notices show Trump administration setting stage for levies on both sectors on national security grounds The Trump administration is kicking off investigations into imports of pharmaceuticals and semiconductors as part of a bid to impose tariffs on both sectors on national security grounds, notices posted to the Federal Register on Monday showed. The filings scheduled to be published on Wednesday set a 21-day deadline from that date for the submission of public comment on the issue and indicate t

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STAT+: Attorneys general want Congress to prohibit PBMs from owning affiliated pharmacies

STAT

Dozens of state attorneys general are urging Congress to pass a law prohibiting pharmacy benefit managers from simultaneously owning pharmacies, arguing such a move would boost competition and create more affordable prescription drug prices for Americans. Their concern is these arrangements create conflicts of interest that allow pharmacy benefits managers to dominate the design of health plans for tens of millions of Americans, and also distort the distribution and pricing for prescription medi

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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‘It looks like I’ve gone 10 rounds with a boxer’: when hay fever becomes debilitating – and potentially deadly

The Guardian - Pharmaceutical Industry

Often dismissed as summertime sniffles, the condition that affects a quarter of UK adults can lead to serious and life-limiting health problems Read more: Pollen peril: how heat, thunder and smog are creating deadly hay fever seasons Sometimes the season starts as early as mid-April; other times its slower to get going. But for Lisa Ventura, June is consistently the cruellest month.

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Innovative approach could improve cancer immunotherapy

European Pharmaceutical Review

New research has proposed a method to increase the effectiveness of tumour-infiltrating lymphocyte (TIL) immunotherapy. Investigators identified that the natural immune protein called CD40L was key in improving TIL cultures in the lab. We discovered that by adding CD40L to the immune cells in the lab, we could dramatically improve the number and quality of cancer-fighting T cells were able to grow, explained Daniel Abate-Daga, PhD, lead author of the study and Scientific Director of the Cell The

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Regulating decentralised manufacturing in the UK – a legal perspective

European Pharmaceutical Review

Governments and the pharmaceutical industry have been considering a novel ways of manufacturing that promises to bring medicinal products, such as their excipients , and medications that are fragile or short-lived, closer to patients. New UK regulations have established the regulatory framework for decentralised manufacturing of medicines in the UK.

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Closure of CDC hepatitis lab imperils U.S. outbreak response, prevention

STAT

An estimated 4 million Americans are infected with hepatitis C, a disease that can go undetected for years. Another 2.4 million people in this country are chronically infected with hepatitis B, which is the leading cause of liver cancer globally. Hepatitis B is preventable, and hepatitis C is curable. But the U.S. capacity to battle these viral scourges has been leveled a devastating blow with the April 1 closure of the country’s premier testing laboratory for viral hepatitis, experts war

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Successful trial results announced for potential rare eye disease treatment

Pharmafile

Eyestem Research, an Indian biotech company, announced successful results from its phase 1 trial of Eyecyte-RPE, a potential therapy for a rare form of dry age-related macular degeneration (AMD), geographic atrophy (GA). GA is an advanced form of AMD, which affects a small number of AMD patients. The phase 1 trial found advancement in visual […] The post Successful trial results announced for potential rare eye disease treatment appeared first on Pharmafile.

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Tech modernization at community health centers in limbo after federal workforce cuts

STAT

The future of a technology modernization program, meant to help the government understand if the billions of tax dollars it spends on community health centers are in fact making Americans healthy, now looks uncertain. The layoffs at the Department of Health and Human Services included dozens of employees at the Health Resources and Services Administration who were working on the technology upgrade, which has been years in the making and was set to launch next month.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Survey suggests Britons with a disability are concerned over AI-integrated healthcare

Pharmafile

A survey conducted by nuom, a British healthcare consultancy, found a majority of UK adults with a disability are concerned that artificial intelligence (AI)-integrated healthcare could prioritise efficiency over inclusivity. Nuom emphasises the need for inclusive technologies that are developed with those with disabilities as AI in healthcare continues to develop.

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Opinion: STAT+: Biotech investors: Stop expecting CRISPR science to make big leaps

STAT

The medical promise of CRISPR gene editing can be seen most easily in current research on oral cancer, which affects more than 50,000 Americans every year. An increasing challenge in the treatment of oral cancer is that tumors become resistant to chemotherapy. By injecting CRISPR gene editing directly in the tumors and targeting the genetic resistance to common chemotherapy agents, we could potentially enable that standard of care for cancer to work once again for patients, overcoming one of the

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Nordic Pharma’s Lacrifill canalicular gel gains CE mark approval and set for European launch

Pharmafile

International pharma company Nordic Pharma has announced that its Lacrifill treatment for dry eye disease has received European Conformity (CE) mark approval. This will allow the company to introduce the product across European markets within a few months and expand its global footprint. Lacrifill is a novel treatment which keeps eyes bathed in their own […] The post Nordic Pharmas Lacrifill canalicular gel gains CE mark approval and set for European launch appeared first on Pharmafile.

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STAT+: Verve gene-editing therapy lowers cholesterol without serious side effects in early study

STAT

Verve Therapeutics said initial data show that its investigational gene-editing therapy lowered cholesterol without inducing serious side effects, a positive step for the company after it paused development of an earlier treatment due to safety concerns. The early data from an ongoing Phase 1 study show that a single infusion of the therapy, called Verve-102, led to greater decreases in “bad” LDL cholesterol with higher doses, according to an announcement Monday.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Inflammatory Biomarker Linked to Type 2 Diabetes Shows Increased Risk of Liver Cancer

Drug Topics

Furthermore, C-reactive protein has greater prognosis for lung cancer, colorectal cancer, and ovarian cancer.

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STAT+: Pfizer to discontinue its GLP-1 pill for obesity due to liver toxicity

STAT

Capping more than two years of stock-gyrating drama, Pfizer said Monday that it would stop development of danuglipron, its experimental oral GLP-1 medicine to treat obesity, focusing its efforts on another medicine with a different mechanism of action. Pfizer said in a press release that an asymptomatic volunteer in the company’s studies experienced “potential drug-induced liver injury,” which resolved after stopping the medication.

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Independent Pharmacies Must Be Prepared For DEA Inspections | AAP 2025

Drug Topics

At AAP 2025, Ron Friedman discussed best practices for responding to a DEA inspection, how to identify any red flags, and best practices for dispensing.

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STAT+: Pharmalittle: We’re reading about Pfizer halting GLP-1 work, FDA use of contractors, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and refreshing because, once again, that predictable routine of meetings, deadlines, and the like has returned. After all, the world keeps spinning. And to cope, yes, we are relying on cups of stimulation to help us along. Our choice today is pumpkin spice.

FDA
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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharmacists’ Expertise Can Improve Patient Outcomes in Transitions of Care

Drug Topics

With transitions of care inclusive of multiple health care settings, each provider must play a specific role to ensure overall improved patient outcomes.

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STAT+: Canada advances an antitrust probe into Express Scripts over ‘patient steering’ and pharmacy fees

STAT

Canadian officials have obtained a court order that requires Express Scripts to produce documents in connection with an investigation into whether the pharmacy benefits manager violated antitrust laws. The Competition Bureau is examining whether the company forced or induced Canadians to use its own pharmacies. Express Scripts operates four mail-order pharmacies across the country, except in Quebec.

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Community Pharmacies Positioned to Ensure OTC Syringe Access

Drug Topics

In a telephone audit, researchers attempted to quantify the frequency of patient barriers when looking to purchase sterile syringes from community pharmacies for over-the-counter use.

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STAT+: An interview with Christi Grimm, and ‘existential’ upheaval at HHS

STAT

This is the online version of STAT’s email newsletter Health Care Inc., delivered to your inbox every Monday.  Sign up here.  STAT has just won a National Magazine Award for General Excellence. It’s a testament to just how hard everyone here works, and if you’re a subscriber, hopefully it shows you’re truly getting some bang for your buck from a trustworthy, diligent news source.

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Accurate Online Education Crucial in Acne Management

Drug Topics

Researchers explored TikToks role in the dissemination of information regarding isotretinoin and its users.

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Pharma’s capital allocation could shift as tariffs threaten an already fragile profit model

PharmaVoice

Major changes to the dynamics of the pharmaceutical ecosystem are making executive decisions even tougher.

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Study Finds COVID-19 Therapies Cause Few Serious Adverse Effects

Drug Topics

However, patients should still be monitored for potential serious adverse effects, as investigators identified potential new concerns.

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Community Pharmacies Actively Advance Clinical Trial Access

Pharmacy Times

Collecting, analyzing, and interpreting data are pharmacist skills.

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Pfizer discontinues its experimental GLP-1 pill

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Morning. Today, we discuss interesting new gene-editing data from Verve, see the NIH starting to convene advisory councils again, and more.

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Kyowa Kirin constructs drug manufacturing facility in Japan

Pharmaceutical Technology

Kyowa Kirin has concluded the construction of its new drug substance (DS) manufacturing facility, the HB7 building in Japan.

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Autism and the gut-brain connection

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning. For those who were curious, our turkey friend at STAT headquarters last week was indeed a wild turkey, not a turkey vulture. A number of images from different angles, checked with multiple amateur ornithologists, all made our neighbor’s species clear.

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Approval moves Columvi earlier in DLBCL treatment pathway

pharmaphorum

Roche has claimed a first-in-class approval in the EU for Columvi in relapsed/refractory diffuse large B-cell lymphoma (DLBCL).

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Verve’s shares jump by more than 26% on Lilly-partnered gene therapy data

Pharmaceutical Technology

Phase Ib results show VERVE-102 reduced LDL-C levels with no serious safety issues, unlike Verves VERVE-101 programme.

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BMS gets another FDA okay for Opdivo/Yervoy combo

pharmaphorum

Bristol-Myers Squibb has claimed its second FDA approval in just a few days for its Opdivo/Yervoy combination, this time in liver cancer.

FDA
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FDA Approves Vyvgart Hytrulo Prefilled Syringe With Self-Injection for Generalized Myasthenia Gravis, CIDP

Pharmacy Times

The new indication expands administration methods for the combination of efgartigimod alfa and hyaluronidase-qvfc, which are already approved for the treatment of some immune-related conditions.