Sun.Feb 19, 2023

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The Power of Individuality

Colors Make me Happy

I often catch myself thinking about the power of social conditioning and the myth of normal that society imposes on us all. The myth of normal tells us that we should follow a certain path and hit a certain milestone by a specific age: school, career, family, retirement, etc. I know first-hand the pressure of cultural norms, the myth of norms. Accordingly, I was supposed to have a career breakthrough during my 20s, find the perfect partner by my early 30s, settle down with kids of my own, and ha

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Prescribing Red Flags, Corresponding Responsibility and DEA Investigations: What’s a Pharmacist To Do?

The FDA Law Blog

Hyman, Phelps & McNamara (“HPM”) Director Larry Houck will present “Prescribing Red Flags, Corresponding Responsibility and DEA Investigations: What’s a Pharmacist To Do?” at this year’s American Pharmacists Association’s (“APhA’s”) Annual Meeting in Phoenix, March 24-27. Mr. Houck was a diversion investigator with the Drug Enforcement Administration (“DEA”) in the field and at agency headquarters for 15 years before joining HPM in 2001.

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What is the best decongestant for ears?

The Checkup by Singlecare

Congestion causes | Common decongestants | Best decongestants for ears | Side effects | Other treatment options | When to see a doctor If you’re experiencing ear congestion while sick with the common cold or the flu, you might be looking for the best decongestant for the ears. The best decongestant will depend on the underlying cause and the type of symptoms present.

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Top 10 Drugs Affected By Renal Function

Med Ed 101

The kidney plays many vital roles in the body. One of those roles is to eliminate medications and their metabolites. When the kidney is not functioning well, drugs are eliminated from the body at a slower rate and can accumulate. Those higher drug concentrations can lead to an increased risk for toxicity. In this post, […] The post Top 10 Drugs Affected By Renal Function appeared first on Med Ed 101.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Alcami Grows Contract Manufacturing and Laboratory Business 20% With Waters Partnership

BioPharm

Read a compelling, detailed Case Study about how an innovation partnership with Waters Corporation enhanced Alcami’s capacity, efficiency, and compliance-readiness for their pharmaceutical manufacturing and analytical services to differentiate their offerings and drive business growth.

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Clover and Adimmune Enters into Exclusive Agreement to Commercialize AdimFlu-S (QIS) Influenza Vaccine in Mainland China

PharmaShots

Shots: Through this agreement, clover received commercial rights for the distribution of AdimFlu-S in mainland China. The NMPA approved it in Jan 2022 for individuals aged ≥3yrs.

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Opinion: In Turkey, Ukraine, and beyond, the necessity of trauma care

STAT

Watching news reports of the heroic relief efforts underway in Turkey and Syria following the devastating earthquake there, I can imagine the terrible weight of emotional trauma that so many people are experiencing right now because I’ve experienced it myself. A dozen years ago, as a young doctor with a background in emergency medicine, I felt prepared to handle disaster response situations.

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AT-1412 by Kling Biotherapeutics for Solid Tumor: Likelihood of Approval

Pharmaceutical Technology

AT-1412 is under clinical development by Kling Biotherapeutics and currently in Phase I for Solid Tumor. According to GlobalData, Phase I drugs for Solid Tumor have a 54% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how AT-1412’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks.

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What is an inner ear infection?

The Checkup by Singlecare

What is an inner ear infection? | Symptoms | Causes | Treatment | When to see a doctor Chances are, you or someone you know has experienced an ear infection. But did you know that there are several different types of ear infections? The most common ear infection —especially in children—is known as otitis media or acute otitis media, which means a middle ear infection.

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Annexuzlimab by MedAnnex for Kidney Cancer (Renal Cell Cancer): Likelihood of Approval

Pharmaceutical Technology

Annexuzlimab is under clinical development by MedAnnex and currently in Phase I for Kidney Cancer (Renal Cell Cancer). According to GlobalData, Phase I drugs for Kidney Cancer (Renal Cell Cancer) have a 76% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Annexuzlimab’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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UK analysis reveals significant increase in hospital admissions for COPD and asthma

Hospital Pharmacy Europe

UK hospital admissions for COPD and asthma have significantly increased over the last 21 years despite an increase in prescribed treatments In an analysis of hospital admissions for both chronic obstructive pulmonary disease (COPD) and asthma from 1999 to 2020, it was found that there was a significant increase for both conditions despite a considerable increase in prescribed treatments for these diseases.

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LYT-200 by Puretech Health for Metastatic Pancreatic Cancer: Likelihood of Approval

Pharmaceutical Technology

LYT-200 is under clinical development by Puretech Health and currently in Phase II for Metastatic Pancreatic Cancer. According to GlobalData, Phase II drugs for Metastatic Pancreatic Cancer have a 32% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how LYT-200’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks.

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Pfizer and Valneva Report Partial Discontinuation of Patient Evaluation in P-III Clinical Trial for VLA15 to Treat Lyme Disease

PharmaShots

Shots: Pfizer has discontinued the evaluation of 50% of the patients with Lyme disease enrolled in the P-III clinical trial (VALOR) that analyses the safety, efficacy & immunogenicity of VLA15 The discontinuation was marked following the violations of GCP at certain clinical trial sites run by a third-party trial site operator. The clinical trials remain ongoing as Pfizer continues to enroll new patients at those sites VLA15 is a Lyme disease vaccine candidate that blocks the outer surface p

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STRO-002 by Sutro Biopharma for Refractory Acute Myeloid Leukemia: Likelihood of Approval

Pharmaceutical Technology

STRO-002 is under clinical development by Sutro Biopharma and currently in Phase I for Refractory Acute Myeloid Leukemia. According to GlobalData, Phase I drugs for Refractory Acute Myeloid Leukemia have a 69% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how STRO-002’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Danburstotug by Sorrento Therapeutics for Cervical Cancer: Likelihood of Approval

Pharmaceutical Technology

Danburstotug is under clinical development by Sorrento Therapeutics and currently in Phase III for Cervical Cancer. According to GlobalData, Phase III drugs for Cervical Cancer have a 68% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how Danburstotug’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks.

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Zelenoleucel by Marker Therapeutics for Refractory Acute Myeloid Leukemia: Likelihood of Approval

Pharmaceutical Technology

Zelenoleucel is under clinical development by Marker Therapeutics and currently in Phase II for Refractory Acute Myeloid Leukemia. According to GlobalData, Phase II drugs for Refractory Acute Myeloid Leukemia have a 23% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Zelenoleucel’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks.