Fri.Aug 19, 2022

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FDA Approves First, Only NMDA Receptor Antagonist for Major Depressive Disorder

Pharmacy Times

Auvelity uses the first new oral mechanism of action for major depressive disorder in more than 60 years.

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Leading by Example

The Honest Apothecary

It is my conviction that managers really do make all the difference in the world. Great managers get great results and build great teams. Bad managers don’t. But it is also my conviction that managers generally mirror the leadership culture created by those they report to. There is, if you will, a “trickle down” effect in the style and priorities of your management.

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NCPA CEO: Three-Quarters of Community Pharmacists Say Filling Open Positions Remains Difficult

Pharmacy Times

Douglas Hoey, PharmD, MBA, CEO of National Community Pharmacists Association (NCPA), discusses potential causes and solutions for the current staffing issues facing so many community pharmacies.

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Hashimoto’s and Graves’ Remission after Helicobacter Pylori Eradication

The Thyroid Pharmacist

While I have a lot of stories of people who recovered their health through removing reactive foods, adding in healing foods, and taking the appropriate supplements, I personally did not get my Hashimoto’s into remission by following those steps. Sure, I felt much better, and my thyroid antibodies significantly dropped with the help of nutrition, but eventually my health problems began creeping back in.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Empagliflozin Reduces Myocardial Glucose Metabolic Rate for Type 2 Diabetes Patients Without Coronary Artery Disease

Pharmacy Times

Treatment with empagliflozin also found to improve cardiac geometry, myocardial mechano-energetic efficiency, and cardiac function.

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Pharma contract manufacturing market to grow to $130bn by 2026

European Pharmaceutical Review

Rising demand for therapeutics, especially in developing markets, is expected to expand the global pharmaceutical contract manufacturing market to $130.2 billion by 2026. The market was valued at approximately $100 billion in 2020. According to market research , factors promoting the 4.6 percent compound annual growth rate (CAGR) of the market include the increasing commercialisation of generics and emerging technologies and small biotechs with limited or no production capabilities driving devel

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Pharmacy Profit Summit Speaker Highlights 2022 Day 1

DiversifyRx

Thank you to everyone who joined us for the Pharmacy Profit Summit 2022! We are still amazed at the lineup of extraordinary speakers at the summit. . Our event did sell out. We know that not everyone who wanted to attend could; even some with tickets got the dreaded positive test and couldn’t make it. In this blog, we will cover some of the highlights of the summit speakers and how you can learn more about them!

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mRNA Vaccines for RSV, Flu, COVID-19 Could Change Immunizations Landscape

Pharmacy Times

Francesca Ceddia, MD, senior vice president of respiratory vaccines at Moderna, discussed how mRNA vaccines could change the treatment landscape for respiratory illnesses.

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Frequently Asked Questions About CCRN Certification 

Board Vitals - Pharmacist

CCRN certification is a special certification granted by the American Association of Critical Care Nurses (AACN). CCRN certification is valuable for nurses, as it allows RNs to care for patients in acute care and/or critical care setting. We’ve compiled some of the most frequently asked questions about CCRN certification to help you prepare for the exam and maintain your licensure.

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Digital Transformation, Shift to Home Care Delivery Have Significant Implications for Specialty Pharmacies

Pharmacy Times

Oncology pharmacists must think critically about the digital experience they give patients.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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What I Packed for a Miami Bachelorette

The Luxe Pharmacist

Hello friends, I cannot wait for my girlfriends bachelorette this weekend in Miami! (Currently publishing this from the airport). I’m expecting a lot of heat given that it’s mid August, so I figured I may as well bring the heat as well! I’m sharing everything I packed and more if you need some inspiration for an upcoming bachelorette trip, date night, girls night out or tropical vacay.

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Introducing COVID-19 Vaccines to Parents of Infants and Toddlers

Pharmacy Times

Ed Cohen, PharmD, FAPhA, drives a discussion around the new inclusion of infants as young as 6 months old within the COVID-19 vaccine recommendations and how to educate parents on the topic.

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Understanding the Patient Journey in Complex and Rare Diseases

Pharmaceutical Commerce

Optimizing the use of data and improving the patient experience go hand in hand.

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Vaccine Administration and Care Management - Pediatric-Specific

Pharmacy Times

Strategies for pediatric-specific care are explored, with an emphasis on vaccine advocation and administration geared toward parents and caregivers.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Positive appraisal for Eisai’s Kisplyx in combination with MSD’s Keytruda

Pharma Times

NICE approval is for first-line treatment of intermediate and advanced renal cell carcinoma

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Daily OTC Pearl: Broncochem

Pharmacy Times

Broncochem is an expectorant syrup to help cough symptoms.

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NHS leaders urge government to act or risk public health emergency

Pharma Times

Senior public health figures take unusual step of warning government about energy costs

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Daily Medication Pearl: Kcentra [Prothrombin Complex Concentrate (Human)]

Pharmacy Times

Kcentra is indicated for the urgent reversal of acquired coagulation factor deficiency induced by vitamin K antagonist therapy in adult patients with acute major bleeding.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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WHO recommends use of Valneva’s vaccine for Covid-19

Pharmaceutical Technology

The WHO Strategic Advisory Group of Experts on Immunization (SAGE) has provided interim policy recommendations for the usage of French company Valneva’s Covid-19 vaccine, VLA2001. According to the recommendations, two 0.5ml intramuscular doses of the vaccine are intended to be given as part of the initial dosing regimen. The second dose should be given a minimum of 28 days following the first shot. .

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Pharmacy Focus Episode 53: Expanding Diversity, Equity in Clinical Health Trials

Pharmacy Times

Using specific data and technology can help advance targeted recruitment goals for trials.

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Celltrion’s Vegzelma receives EC approval for cancer treatments

Pharmaceutical Technology

The European Commission (EC) has granted approval for Celltrion Healthcare ’s Vegzelma (CT-P16) to treat metastatic breast cancer, advanced and/or metastatic renal cell cancer, non-small cell lung cancer, ovarian cancer, metastatic carcinoma of the colon or rectum and cervical cancer. Vegzelma (CT-P16) is a bevacizumab biosimilar referencing Genentech’s Avastin, which is approved in the EU.

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Prevent Drug Interactions With Paxlovid

Pharmacy Times

Resources for health care professionals include FDA’s patient eligibility screening checklist tool for prescribers.

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UK NICE recommends Vifor’s Tavneos for AAV treatment

Pharmaceutical Technology

The UK National Institute for Health and Care Excellence (NICE) has r ecommended Vifor Fresenius Medical Care Renal Pharma’s Tavneos (avacopan) plus rituximab or cyclophosphamide to treat adults with two ANCA-associated vasculitis (AAV) forms. The treatment is indicated for severe, active granulomatosis polyangiitis (GPA) or microscopic polyangiitis (MPA), which are the two forms of AAV.

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Cancer Patients Self-Report Significant Improvement in Quality of Life With Immune Checkpoint Inhibitors

Pharmacy Times

Researchers suggest that immune checkpoint inhibitors significantly preserve the quality of life in patients with cancer.

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Oncopeptides gets EU nod for myeloma drug Pepaxti ahead of US adcomm

pharmaphorum

The European Commission has approved Oncopeptides’ Pepaxti in combination with dexamethasone for multiple myeloma patients with so-called triple class refractory disease – in other words those who don’t respond to all three of the major classes of treatment for the blood cancer. The approval means that Pepaxti (melphalan flufenamide) can now be used as a rescue therapy for adults with multiple myeloma who have previously failed treatment with at least one proteasome inhibitor, one im

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FDA Accepts sBLA for Genentech’s Polivy Combination for Diffuse Large B-Cell Lymphoma

Pharmacy Times

The treatment regimen is first in more than 20 years to significantly improve outcomes in individuals with the fast-growing cancer, according to the company.

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Troubled Nordic Nanovector “exploring strategic options”

pharmaphorum

Reeling from the recent failure of its lead product in a pivotal trial, Nordic Nanovector has formally started a restructuring process and called in investment bank Carnegie to help explore its options. The Norwegian biotech was hit hard in July when the PARADIGME study of Betalutin ( 177 Lu lilotomab satetraxetan) – an anti-CD37 antibody radionuclide conjugate being tested as a third-line therapy for patients with follicular lymphoma – was abandoned after being plagued with recruitment issues.

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Expert Discusses White House Meeting to Address Increasing Colorectal Cancer Screenings, Health Equity

Pharmacy Times

Andrew Barnell, MBA, CEO and co-founder of Geneoscopy, discusses his meeting at the White House on President Biden’s Cancer Moonshot initiative.

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CSL preps filings for once-monthly antibody for HAE

pharmaphorum

Australia’s CSL has said its one-monthly treatment for hereditary angioedema has shown it is safe and effective in a phase 3 trial, and will be filed for approval in its current financial year which ends on 30 June next year. The VANGUARD trial of garadacimab, a Factor XIIa inhibitor, compared a subcutaneous injection of garadacimab given every four weeks to placebo on its ability to prevent the swelling attacks that are a key feature of HAE.

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Grand River Aseptic Manufacturing Installs Sterile Filling Lines

Pharmaceutical Commerce

CDMO filling capacity now exceeds 50 million units yearly.

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Fuelling the efficiency of drug development through sensor data integration

pharmaphorum

Who remembers that line from the movie Zoolander, “ the files are IN the computer ?!” Twenty years later and we’re now all painfully familiar with our computer’s file structure. But as we continue to digitise clinical trials, has access to new streams of valuable data become easier because “the data is IN the cloud”? Connected sensor technologies and tools, from wearables, smart speakers, and bed mats to ingestible sensing capsules and implantables, are capturing unprecedented flows of data with

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Key Players Highlight Oncology Pharmacists’ Critical Role in Advancing the Field

Pharmacy Times

Professionals address key challenges including structural racism and the hematology-oncology pharmacist great migration.

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Grünenthal takes non-opioid pain drug resiniferatoxin into phase 3

pharmaphorum

Grünenthal has moved its painkiller resiniferatoxin into phase 3 trials in patients with osteoarthritis, hoping to find an option that sidesteps the side effects and addictive potential of opioid drugs. The German pharma acquired rights to the TRPV1 agonist also known as MTX-071 last year when it acquired Swiss biotech Mestex, and has started dosing patients in one of three planned phase 3 trials in osteoarthritis of the knee.