Mon.Jun 05, 2023

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Acute Cardiac Events Common During Hospitalization for COVID-19

Drug Topics

Patients were more likely to require ICU admission.

Hospitals 469
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BIO’s CEO digs into the hot-button issues facing the industry

PharmaVoice

Rachel King took the reins at BIO during a rocky time. Now, after steadying the ship, she’s brought the trade association’s focus back to the industry’s most pressing priorities.

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Morning RX: June 5, 2023

Drug Topics

Mandy Cohen is set to become the next CDC director, Medicare will cover a new class of Alzheimer’s drugs, and the WHO announces a landmark digital health initiative.

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Why Choose a Career in Community Pharmacy?

Pharmacy Times

It’s imperative to redefine the future of pharmacy to help ensure a robust pipeline of future pharmacists and create a culture that helps ensure pharmacists live their purpose and passion.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Apple rolls out mental health tracking, vision assessment as new health app features

Fierce Healthcare

The roughly half of American smartphone users with iPhones will notice new health and pri | Apple brings its Health app to the iPad while offering new vision and mental health features to its suite of devices.

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FDA Approves First Intravenous Iron Replacement Therapy for Adults With Heart Failure, Iron Deficiency

Pharmacy Times

Treatment with Injectafer significantly improved exercise capacity compared to placebo in a randomized clinical trial in adult patients with heart failure.

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More Trending

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Younger people driving more high-cost claims for employers: survey

Fierce Healthcare

Self-insured employers face myriad challenges in trying to manage growing healthcare costs, and one of those results from recent history, according to a

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Janssen and Legend’s longtime collaboration lands a CAR-T win at ASCO

PharmaVoice

A partnership going on six years between the pharma giant and the Chinese biotech is showing that their CAR-T cell therapy for multiple myeloma is highly effective.

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STAT+: FDA removes neurologist with financial ties to Eisai and Biogen from Alzheimer’s advisory panel

STAT

The Food and Drug Administration has removed a neurologist with financial ties to Biogen and Eisai — which jointly develop and market a pair of controversial Alzheimer’s drugs — from an upcoming advisory panel meeting to review one of those treatments. David Weisman was cleared two months ago by the agency as a temporary voting member of an advisory committee that will meet Friday to consider whether a drug called lecanemab, which is promoted by the companies, should be full

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Home health bidding wars heat up: Optum makes $3B unsolicited offer for Amedisys

Fierce Healthcare

The home health bidding wars are heating up as UnitedHealth Group's Optum unit is making a big play for home health and hospice firm Amedisys. |.Just one month ago, Amedisys agreed to be bought by another healthcare company, Option Care Health, a provider of post-acute care and infusion services.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Study Finds Association Between Vitamin D Levels, Obesity in Infertile Women

Pharmacy Times

Research notes that modifiable lifestyle factors, such as overconsumption of food and vitamin deficiency, can affect pregnancy.

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STAT+: Carbon Health is already using AI to write patient records

STAT

SAN FRANCISCO — Primary care tech startup Carbon Health is using artificial intelligence to listen in on patient appointments and automatically write up near-complete notes within minutes, directly in its own electronic health record software. Carbon — which has raised about $750 million in venture funding, including $100 million earlier this year — has been developing the AI-based health record software over the past few months and began using it on patients last month.

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Long-term Data Show Efficacy of Amivantamab-vmjw Combination for Patients With Mutated Advanced Non-Small Cell Lung Cancer

Pharmacy Times

In data presented at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting, amivantamab-vmjw plus lazertinib demonstrated promise as a first-line treatment for patients with advanced EGFR-mutated non-small cell lung cancer.

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ASCO: Moderna, Merck melanoma vaccine set for phase 3

pharmaphorum

ASCO: Moderna, Merck melanoma vaccine set for phase 3 Phil.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Clinical Overview: Steps to Implementation of Rebyota for Recurrent C difficile Infection

Pharmacy Times

Rebyota is a live biotherapeutic product that is unfamiliar to many pharmacists and other health care providers with different steps in the eventual administration process.

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Cybersecurity in pharma: Securing the future

Pharmaceutical Technology

Earlier this year, Sun Pharmaceutical Industries , one of India’s largest generic drug producers, reported a major cybersecurity breach , impacting its business operations. A ransomware group later claimed responsibility for the incident, which was one of several high-profile cybersecurity breaches in India over the past three years. Pharma companies around the world have also faced similar threats , some of which have impacted national security and public health.

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Transcarent taps Andy Roddick's ViewFi for virtual orthopedic, MSK consults

Fierce Healthcare

Employee healthcare navigation company Transcarent has lined up its latest partnership, this time with digital health company ViewFi. | ViewFi is a virtual care platform built for orthopedic and musculoskeletal injuries and care. The company offers virtual healthcare, at-home exams and one-on-one appointments with orthopedic doctors and surgeons. Transcarent members will have access to some of the same orthopedic specialists that provide care to professional athletes.

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‘We arguably saved their lives’: Newborn DNA-sequencing reveals elevated cancer risks for parents

STAT

Ten years ago, clinicians in a handful of hospitals around the United States began sequencing the genomes of apparently healthy babies, seeking to understand how the technology might turn up hidden genetic disorders that aren’t being caught by routine newborn blood testing. New research from one such trial suggests the impact of having that kind of information extends far beyond the baby whose DNA is being decoded.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Humana opens 250th primary care center as it continues to focus on growth

Fierce Healthcare

Humana's primary care arm opened its 250th clinic in Dallas on Tuesday, marking another milestone in the insurer's growth in the provider space. | Humana's primary care arm opened its 250th clinic in Dallas on Tuesday, marking another milestone in the insurer's growth in the provider space.

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STAT+: Ted Love, BIO’s first Black board chair, aims to rehab biotech’s image in Washington

STAT

WASHINGTON — Ted Love has pretty much done everything there is to do in biotech. He’s worked for tiny startups and mega corporations. He sold his latest company to Pfizer for $5 billion amid an industry downturn. And now, he’s taking on a new challenge by becoming the chair of the board of the largest biotechnology lobby, BIO.

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Medicare Still Won’t Pay for Alzheimer’s Drugs Without Confirmatory Data

PharmExec

Indicates that reimbursement for new slate of Alzheimer’s treatments will occur only with the completion of studies to support full approval.

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Consumers notice rising retail crimes

Drug Store News

According to a survey conducted by the National Retail Federation, consumers believe retail crimes have increased in their community.

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Akero’s NASH drug combined with Ozempic cut liver fat in small study

STAT

GLP-1s, a class of drugs including Ozempic and Wegovy that have become widely popular for treating obesity and diabetes, are also being studied for NASH , a form of fatty liver disease. But a new small study suggests GLP-1s may not dominate the disease area as they have others. Akero Therapeutics tested its experimental medicine efruxifermin in conjunction with a GLP-1, and found that patients taking the combination had reduced liver fat and improved markers of liver scarring compared with those

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Analysis reports nitrosamine prevalence in small molecule drugs

European Pharmaceutical Review

Based on an in silico analysis of over 12,000 small molecule drugs and drug impurities , a recent paper has reported that the presence of nitrosamines in pharmaceuticals is likely more prevalent than originally expected. In total, 40.4 percent of the analysed active pharmaceutical ingredients (APIs) and 29.6 percent of the API impurities were revealed as potential nitrosamine precursors.

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STAT+: How Blue Cross Blue Shield insurers ratcheted up profits in 2022

STAT

A $203 million tax refund for Blue Cross Blue Shield of North Carolina. Nearly $1.5 billion in profit for Health Care Service Corp., the parent of five Blues plans. A quadrupling of profit at BCBS of Alabama. Publicly traded health insurers were not the only ones in the industry that continued to amass large windfalls in 2022. Many nonprofit and private Blue Cross Blue Shield companies ended last year with sizable gains that added to their mountainous cash reserves, according to a STAT analysis

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Study identifies key contamination source during ATMP manufacture

European Pharmaceutical Review

A two-year study monitoring microbial contamination of adipose tissue-derived stem cells (ADSC)-based advanced therapy medicinal products (ATMP) during manufacture , showed over 40 percent of lipoaspirate samples were contaminated with thirteen different microorganisms. over 40 percent of lipoaspirate samples [from ADSC-based ATMPs] were contaminated with thirteen different microorganisms” This is the first study to show this observation, according to the authors of the paper.

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For many who use power wheelchairs, CMS decision just made seat elevation much less expensive

STAT

This article is adapted from STAT’s latest report , Decoding Medicare: 10 key coverage decisions and how they’re made. F or years, patients and medical groups have advocated for Medicare to cover wheelchairs with power-seat elevation, allowing users to, among other things, reach cabinets and countertops more easily and conduct conversations eye to eye.

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ASCO: Vorasidenib shows its glioma potential in INDIGO

pharmaphorum

ASCO: Vorasidenib shows its glioma potential in INDIGO Phil.

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STAT+: Bellerophon Therapeutics trial fails despite innovative digital endpoint

STAT

In an important reminder that plugging digital tools into a clinical trial will not magically solve problems, Bellerophon Therapeutics announced Monday it would abandon a study of its treatment for pulmonary fibrosis after patients in a Phase 3 trial using a digital endpoint showed no improvement. Bellerophon’s study, which the New Jersey-based company boasted was the first pivotal trial to use a Food and Drug Administration-endorsed endpoint using wearable data, was closely watched by la

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Dollar General cutting pack on Popshelf format amid tough Q1 results

Drug Store News

Dollar General reported a tough quarter as its core customers cut back on non-essential spending on discretionary goods.

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Selvita and the University of Oxford join forces to tackle Parkinson’s disease

Pharmaceutical Technology

The Polish drug discovery and service provider Selvita has announced a new collaboration with the University of Oxford to advance the development of Parkinson’s disease therapies. Parkinson’s is caused by a build-up of alpha-synuclein, a small protein, forming aggregates inside vulnerable neurons. Cells are then unable to efficiently clear these aggregates, potentially killing neurons and allowing the disease to progress.

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TensCare intros Kegel Toner

Drug Store News

The Kegel Toner is a pelvic floor exerciser designed so users can regain control of their bladder and speed up postpartum recovery, the company said.

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STAT+: Gilead’s CAR-T therapy prolongs survival in key blood cancer trial

STAT

CHICAGO — Yescarta, the CAR-T therapy made by the Kite unit of Gilead Sciences, prolonged the lives of patients with large B-cell lymphoma by 27% compared to standard treatment in a long-running clinical trial, researchers reported Monday. Proving a meaningful survival benefit for patients with a type of blood cancer represents another milestone for CAR-T therapy, which involves extracting white blood cells from a patient and genetically modifying them to attack cancer.