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STAT+: FDA alters warning label for Carvykti CAR-T, although link to secondary cancers is unclear

STAT

The Food and Drug Administration issued a change to the warning label for Legend Biotech and Janssen’s myeloma CAR-T, Carvykti or cilta-cel, adding that some secondary blood cancers have occurred following treatment for multiple myeloma with the cell therapy. 

Labelling 106
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New data reinforce Keytruda’s dominance in first-line lung cancer

pharmaphorum

Furthermore, the duration of response with the PD-1 checkpoint inhibitor was nearly five times longer at 29 months versus just over six months with frontline chemotherapy.

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Enhancing collaboration to optimise medication therapy in older adults with cancer: a position paper from SOFOG-SFPO

Hospital Pharmacy Europe

In this heterogeneous patient group, decisions on therapies and management must follow a multidimensional approach, integrating medical, socio-economic and psychological factors. Drug classes known to cause falls are commonly used in older patients , but cancer treatment can further increase this risk.