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FDA drug dosage optimisation guidelines signal clinical trial reform

Pharmaceutical Technology

In January, amidst calls to improve patient safety by optimizing licensed drug formulations, the FDA released a draft guidance that signalled a departure from the most commonly used method of identifying a new therapy’s ideal dosage. The focus on identifying the ideal drug dosage is not new. What is drug dose optimisation?

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Ondansetron for cats: Dosage and safety

The Checkup by Singlecare

The most common reasons ondansetron is needed in cats are chemotherapy, drug treatment, and pancreatitis (inflamed pancreas). Communication between the brain’s nausea center and the gastrointestinal tract is blocked, so the brain can’t activate the vomiting reflex. As in humans, doses may be given both before and after chemotherapy.

Dosage 52
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Cymbalta generic availability, cost, and dosage

The Checkup by Singlecare

Chemotherapy-Induced Peripheral Neuropathy Studies have shown that duloxetine may help prevent or reduce nerve pain in people who have been treated with chemotherapy. Communicate any concerns or questions about the switch to your healthcare provider, as they can offer personalized advice based on your medical history and overall needs.

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Amoxicillin for cough and cold symptoms: What experts say

The Checkup by Singlecare

It is important to communicate all of your symptoms and a timeline of when they started with your healthcare provider, who will determine the best course of treatment. Exceptions include people who have a compromised immune system, are taking steroids, or are in chemotherapy. It can be caused by bacteria or by a virus.

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International regulation: the importance of quality assurance in drug development

European Pharmaceutical Review

Since the first ADC was approved by the EMA in 2012, they have generated a great deal of interest in the oncology field because of their potential to address many of the challenges of traditional chemotherapy options. Teams must also accept the variety of analytical procedures these regulatory agencies prefer.

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6 Surprising Medications That May Cause Hearing Loss

BuzzRx

Losing hearing permanently can have a profound impact on a person’s ability to communicate and, consequently, on their personal, professional, and social life. Chemotherapy Drugs Chemo drugs like cisplatin and carboplatin are used to kill cancer cells. Always read drug labels carefully and do not take more than the recommended dosage.

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SPuMoNI: Enhancing Pharma Data Quality through Smart Technologies

ISPE

End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation.” Mexican Governor: Cancer Children Given Water Instead of Chemotherapy.” You may unsubscribe from these ISPE communications at any time. Lakerveld, B. Benyahia, P. Barton, R. Braatz, et al. doi:10.1002/anie.201305429