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Oral COVID Agents

Pharmacy Friday Pearls

18 years Administration Oral Oral Oral PK/PD MOA: Nirmatrelvir – inhibitor of the SARS-CoV-2 main protease Prevents viral replicationRitonavir is a CYP3A inhibitor included to increase nirmatrelvir plasma levelsRitonavir alone has NO activity against SARS-CoV-2 Time to peak: Nirmatrelvir: 3 hrs & Ritonavir: 3.98 Introduction.

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Pharma’s post-pandemic launch performance problem: what’s the prognosis?

pharmaphorum

COVID vaccines and treatments have created a substantial market over and above the existing Rx market- IQVIA estimates that the cumulative value of COVID vaccines could be between $185 and 295bn to 2026. The initial pandemic lockdowns prevented many patients from seeing doctors face-to-face.

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Ivermectin: A therapeutic approach to reduce high-risk cases of COVID

Druggist

With that faith, a research article was published in the May-June issue of the “American Journal of Therapeutics,” stating the regular use of Ivermectin may significantly reduce the risk of covid-19 infection. Additionally, this drug is also known as anti-parasite successful against all viruses like HIV, Dengue, Influenza , and Zika virus.

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How Balancing Iron Levels Can Help Your Thyroid

The Thyroid Pharmacist

I have been writing this article for almost 10 years, and keep finding new and more reasons and solutions for iron issues, so I think you will definitely discover something new. Today, we’ll be focusing on iron deficiency anemia (for more detailed information on the other two types of anemias, please see my B12 and MTHFR articles).

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Agile, Data-Driven Life Cycle Management for Continuous Manufacturing

ISPE

This article provides a review on the current state of CM implementation, offers insights into life cycle management and regulatory aspects, and explains how a data- and knowledge-centric approach to risk management can help CM achieve its full potential. This is demonstrated by the rise from $1.05 billion US in 2021 to $1.9

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How Do Adaptogenic Herbs Benefit Hashimoto’s?

The Thyroid Pharmacist

For the purposes of this article, I’d love to do a deep-dive focus on adaptogenic herbs, as one way to increase our body’s resilience and lower the impact of all types of chronic stress. This article features a long list of adaptogens, each of which has fascinating and unique properties. This can also mean fewer nutrients are absorbed.