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Health Canada grants expanded authorisation for Novavax’s Covid-19 vaccine

Pharmaceutical Technology

According to data from Phase III trials, the booster dose elicited greater immune responses to levels in line with or over those linked to protection against Covid-19. Additionally, data from these trials showed that local and systemic reactions following the booster dosing lasted for a median duration of nearly two days.

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Low Dose Naltrexone and Hashimoto’s

The Thyroid Pharmacist

However, low doses of this medication (hence, low dose naltrexone or LDN), have been found to modulate the immune system and have shown promise in improving cases of autoimmune disease. These include Crohn’s, MS, and Hashimoto’s, as well as other immune system-related conditions such as cancer and HIV/AIDS. Doses of 1.5-4.5

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Novel injectable bispecific antibody epcoritamab approved in EU and UK for advanced lymphoma

Hospital Pharmacy Europe

It is designed to simultaneously bind to both the cluster of differentiation (CD)3 proteins on immune T cells and the CD20 proteins on cancerous B cells and activate the T cell to destroy the B cell. Four patients (2.4%) experienced a fatal adverse reaction – ICANS in one patient (0.6%) and pneumonia in three patients (1.8%).

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FDA Approvals: September 2022 Recap

Digital Pharmacist

Common adverse reactions include conjunctival/ocular hyperemia, photophobia, blurred vision, dry eye, pain, headache, irritation, and visual impairment. . Common adverse effects include serious or fatal respiratory failure, ischemic events, abdominal pain, nausea, and diarrhea, among others. .

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FDA slaps hold on trials of Gilead’s CD47 drug magrolimab

pharmaphorum

The regulatory move applies only to trials of magrolimab given alongside Bristol-Myers Squibb’s Vidaza (azacitidine), and stems from an “imbalance” in investigator-reported serious adverse events between study arms, said the drugmaker.

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How to counsel your patients with long COVID

The Checkup by Singlecare

Cardiovascular events: Patients with pre-existing heart conditions may be at a higher risk of a heart attack or stroke after having COVID. Immune problems: Autoimmune conditions in which the immune system mistakenly attacks healthy cells can develop and lead to a range of autoimmune diseases.

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Methotrexate interactions to avoid

The Checkup by Singlecare

Prescribing information for both probenecid and methotrexate mentions the risk of developing severe adverse reactions when these medications are taken concomitantly. Finally, methotrexate may suppress the immune system , so avoiding unwashed fruits and vegetables or unpasteurized milk and soft cheeses is best.