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Takeda farms out cancer drug alisertib to Puma Biotech

pharmaphorum

Enter Puma Biotech, which is paying a modest $7 million upfront for rights to alisertib (formerly MLN8237) and plans to run clinical trials of the compound in breast and lung cancers. Takeda is also in line for just over $287 million in potential milestone payments, plus royalties on net sales if it reaches the market.

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How Myo-inositol Can Improve Hashimoto’s Symptoms

The Thyroid Pharmacist

While the human body (via the liver and kidneys) can produce up to 4 g/day of inositol, it has been found that the overly processed, high glucose (and low fiber) Western diets that many people follow, only provide about 1 g/day of the compound. (7). 2015 Aug;67(4):321-5. Recommended Dosage and Precautions. 2017;18(10):2187.

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Jiashu Xie, PhD

Blog: Ask a Student Pharmacist

Jiashu Xie, PhD eomizowh Wed, 06/21/2023 - 10:11 Expand all + Biography Research Summary Current research in the Pharmacokinetics (PK) lab has focused on profiling the in vitro ADME (absorption, distribution, metabolism, and excretion) and in vivo PK properties of lead compounds from medicinal chemistry efforts. 2015; 25(19): 4320-4324.

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Solutions for Constipation Relief

The Thyroid Pharmacist

Chemotherapy agents: Chemotherapy agents can lead to constipation in a variety of ways such as slowing the movements of the intestinal tract or creating inflammation that disrupts digestive function. According to a 2015 research review, 100 milligrams of ginger extract may increase bowel movements. [63] 2020;12(1):205.

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Novel oral chemotherapeutic holds potential for stomach cancer patients

European Pharmaceutical Review

The availability of oral chemotherapy treatments would provide stomach cancer patients with the option of more efficacious drugs with improved tolerability in a more convenient dosage format” The poor clinical outcomes of stomach cancer make it a key target for drug development. Benefits of daily oral chemotherapy over IV.

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Understanding Biologics and Biosimilars Amid an Evolving Treatment Landscape

Pharmacy Times

Clinical Applications and Economic Impacts Biologics have significantly impacted cancer therapies by targeting cancer cells more specifically and reducing adverse events compared with traditional chemotherapy, Darkow noted. billion worth in savings in 2023 and $36 billion since the first biosimilar entered the market in 2015.

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Beating the Big C

Pharmaceutical Technology

Analysts predict Pfizer’s revenue stream would be slashed by 25% by 2015 if the company did not branch out into other areas. In addition, cancer drugs can reach the market twice as fast as the average medicine and, when they do get there, they can be extremely lucrative. .”