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The Important Role that Biopharmaceutics Plays in Accelerating Early-Phase Drug Development

Pharmaceutical Technology

Our chemists and formulation scientists review the properties of new drug candidates and “work their magic” to develop formulations that improve the exposure profile of the compound. How does bioavailability play a role in biopharmaceutics? Now fraction absorbed and bioavailability are often confused and used interchangeably.

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2022 spells change for EU pharmaceutical legislation

European Pharmaceutical Review

The review was impacted by Brexit and the COVID-19 pandemic, which compounded existing issues surrounding high drug pricing and patient access that had been brewing since 2016 and highlighted several shortcomings in the EU’s pharmaceutical system. Brussels; 2020. EUROPEAN PARLIAMENT AND THE COUNCIL OF THE EUROPEAN UNION; 2022.

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Does coffee affect your cholesterol?

The Checkup by Singlecare

Coffee itself doesn’t contain any cholesterol, but its natural oils contain kahweol and cafestol , two chemical compounds that have the potential to raise cholesterol levels. In other words, yes, the chemical compounds in coffee can raise cholesterol, but the effect coffee has on your cholesterol depends on individual factors.

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Roivant joins RNA splicing push with Eisai deal

pharmaphorum

The compound, called H3B-8800, is currently in phase 1 testing in the US and Europe in patients with myelodysplastic syndrome (MDS) who carry mutations in splicing factor 3B subunit 1 (SF3B1) by Eisai’s H3 Biomedicine subsidiary.

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Botanical drugs – what is the best way forward for regulatory and market approval?

European Pharmaceutical Review

11 The THR pathway was created with the purpose of establishing a simplified registration procedure for all traditional herbal medicines that do not fulfil the requirements for the MA (strict) pathway under Directive 2001/83/EC. 10,12 The THR scheme is also limited to products used for oral or external use and/or inhalation. 2012/1916).

FDA 103
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10 home remedies for a cough

The Checkup by Singlecare

Licorice root Licorice is an herb that contains a number of compounds that fight inflammation and bacteria and boost the immune system, such as polysaccharides, flavonoids, and triterpenes. You can either boil ginger in water or make ginger tea and drink it three to four times a day or chew fresh raw ginger to reduce a cough.

Hospitals 104
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Three strategies for managing loss of exclusivity successfully

pharmaphorum

Eli Lilly’s Humalog compound and formulation patents expired in 2013 and 2014, respectively. AstraZeneca’s patent for its top-selling gastroesophageal reflux disease drug was due to expire in 2001. Simultaneous with the switch to NEXIUM, AstraZeneca grew its overall Gastroenterology franchise – by nearly 9% from 2001 to 2002.